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Cited by 212Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMemory and Neural MechanismsChild and Adolescent Psychosocial and Emotional Development

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Baseline and fear-potentiated startle in panic disorder patients

Grillon, Christian, Ameli, Rezvan, Goddard, Andrew, Woods, Scott W., Davis, Michael·1994·Biological Psychiatry
DOI 10.1016/0006-3223(94)90040-x
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Abstract

The present study investigated whether patients with panic disorder had an increase in the startle response and whether this effect, if present, was specific to anticipatory anxiety. The eyeblink component of the acoustic startle reflex was measured in a paradigm involving the anticipation of electric shocks (fear-potentiated startle) in 34 patients with panic disorder and 49 healthy controls. Startle was also recorded in the absence of specific threat at the beginning and at the end of the testing. The testing consisted of three phases: adaptation, fear-potentiated startle, and recovery. In the adaptation and recovery phases, startle stimuli were delivered in the absence of threat. In the fear-potentiated startle phase, startle stimuli were delivered in threat conditions, when subjects anticipated shocks, and in safe conditions that predicted the absence of shocks. Startle was larger in the younger patients (age or = 39 years old), compared to the older controls. The results are discussed in terms of the contextual effects of the experimental setting.

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Crossref · 10.1016/0006-3223(94)90040-x

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45 of 45 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 1

  1. Balaban, 1986, Offline latency and amplitude scoring of the human reflex eyeblink with Fortran IV (computer program abstract), Psychophysiology, 23, 612

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Metadata

Authors
Grillon, C., Ameli, R., Goddard, A., Woods, S. W., & Davis, M.
Affiliations
  • Yale University (US)
  • Connecticut Mental Health Center (US)
Corresponding author
Grillon, Christian
ORCID
Venue
Biological Psychiatry
Publisher
Elsevier BV
Published
1994-04
Volume
35
Issue
7
Pages
431-439
ISSN
0006-3223 (ISSN-L)
DOI
10.1016/0006-3223(94)90040-x
OpenAlex
W2030392869
Cited by
212
References
45
Citations by year
2026: 1 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 6 · 2021: 4 · 2020: 5 · 2019: 2 · 2018: 7 · 2017: 6 · 2016: 3 · 2015: 6 · 2014: 5 · 2013: 14 · 2012: 11
FWCI
6.36
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Biological Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r29mh050720-05)
  • National Institute of Mental Health (NIMH 1 R29 MH50720, NIMH MH-47840, 2-PO1-MH25642, P01MH025642)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
panic disorder, fear-potentiated startle, acoustic startle response, anticipatory anxiety, eyeblink response, age differences, contextual effects, threat anticipation
MeSH terms
Adolescent, Adult, Anxiety, Blinking, Electromyography, Fear, Female, Humans, Middle Aged, Psychiatric Status Rating Scales, Reflex, Startle, Panic Disorder

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