Physiologic Responses to Loud Tones in Israeli Patients With Posttraumatic Stress Disorder

Shalev, Arieh Y.

doi:10.1001/archpsyc.1992.01820110034005

Cited by 236Posttraumatic Stress Disorder ResearchTraumatic Brain Injury ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Physiologic Responses to Loud Tones in Israeli Patients With Posttraumatic Stress Disorder

Shalev, Arieh Y.·1992·Archives of General Psychiatry

DOI 10.1001/archpsyc.1992.01820110034005

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Abstract

Orbicularis oculi (eye blink) electromyogram, skin conductance, and heart rate responses to 15 consecutive 95-dB, 500-millisecond, 1000-Hz tones with 0-millisecond rise and fall times were measured in 14 patients with posttraumatic stress disorder, 14 patients with other anxiety disorders, 15 mentally healthy subjects with past traumatic experiences, and 19 mentally healthy subjects with no trauma history. The patients with posttraumatic stress disorder showed significantly larger skin conductance and heart rate responses and a trend toward larger electromyogram responses to the tones than every other group. These effects were not explained by subjective anxiety, resting physiologic arousal, physiologic arousal preceding the tone trials, or initial physiologic responsivity. The group with posttraumatic stress disorder was the only one that failed to show habituation of skin conductance responses.

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Enhanced HPA-negative feedback has been reliably observed in patients with PTSD.
“Enhanced ASR and HPA-negative feedback have been reliably observed in patients with PTSD (Shalev et al, 1992;Yehuda et al, 1993;Orr et al, 1997).”
From Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress (2012) · cites this paper as Shalev et al, 1992
Enhanced ASR has been reliably observed in patients with PTSD.
“Enhanced ASR and HPA-negative feedback have been reliably observed in patients with PTSD (Shalev et al, 1992;Yehuda et al, 1993;Orr et al, 1997).”
From Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress (2012) · cites this paper as Shalev et al, 1992

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Authors: Shalev, A. Y.
Affiliations: Hadassah Medical Center (IL)
Corresponding author: Shalev, Arieh Y.
ORCID: Shalev, Arieh Y.
Venue: Archives of General Psychiatry
Publisher: American Medical Association (AMA)
Published: 1992-11-01
Volume: 49
Issue: 11
Pages: 870
ISSN: 0003-990X (ISSN-L)
DOI: 10.1001/archpsyc.1992.01820110034005
OpenAlex: W2040357544
Cited by: 236
References: 37
Citations by year: 2026: 3 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 8 · 2015: 5 · 2014: 4 · 2013: 9 · 2012: 3
FWCI: 8.35
Type: journal article
Language: en
Open access: closed
Locations: Archives of General Psychiatry (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: post-traumatic stress disorder, skin conductance, heart rate, blinking, anxiety disorders, habituation, autonomic arousal, trauma history
MeSH terms: Acoustic Stimulation, Adult, Anxiety Disorders, Arousal, Blinking, Diagnosis, Differential, Female, Galvanic Skin Response, Habituation, Psychophysiologic, Heart Rate, Humans, Life Change Events, Male, Reflex, Startle, Stress Disorders, Post-Traumatic

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Physiologic Responses to Loud Tones in Israeli Patients With Posttraumatic Stress Disorder

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