Barbiturate-induced glycogen accumulation in brain. An electron microscopic study.
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Glycogen granules are exclusive to astrocytes within the central nervous system and serve as an energy reserve.
“Glycogen granules are exclusive to astrocytes within the central nervous system and serve as an energy reserve, particularly important in regulating neuronal metabolismo (Phelps, 1972; Vezzoli et al., 2020)”
From Aging promotes an increase in mitochondrial fragmentation in astrocytes (2024) · cites this paper as Phelps, 1972
Glycogen granules are a feature unique to astrocytes in the brain and can be used to identify astrocytes in electron microscopy.
“The mitochondria analyzed were exclusively from cells containing glycogen granules in the cytoplasm, a feature unique to astrocytes in the brain. In electron microscopy images, glycogen appears as electron-dense, spherical granules within astrocytic processes (Phelps, 1972; Vezzoli et al., 2020).”
From Aging promotes an increase in mitochondrial fragmentation in astrocytes (2024) · cites this paper as Phelps, 1972
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Aging promotes an increase in mitochondrial fragmentation in astrocytes
Araujo, A. P. B., Vargas, G., Hayashide, L. D. S., Matias, I., Andrade, C. B. V., de Carvalho, J. J., Gomes, F. C. A., & Diniz, L. P. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1496163 · Cited by 43 · see citing works
- Authors
- Phelps, C. H.
- Affiliations
- UConn Health (US)
- Corresponding author
- Phelps, Creighton H.
- Venue
- Brain Research
- Publisher
- Elsevier BV
- Published
- 1972-04
- Volume
- 39
- Issue
- 1
- Pages
- 225-234
- ISSN
- 0006-8993 (ISSN-L)
- OpenAlex
- W2013387855
- Cited by
- 154
- References
- 0
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 2 · 2023: 1 · 2021: 1 · 2020: 3 · 2019: 12 · 2018: 4 · 2017: 6 · 2016: 2 · 2015: 5 · 2014: 4 · 2013: 6 · 2012: 5
- FWCI
- 1.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Developmental Neuroscience › Anesthesia and Neurotoxicity Research
- Health Sciences › Medicine › Rheumatology › Glycogen Storage Diseases and Myoclonus
- Keywords
- barbiturates, sodium phenobarbital, brain glycogen, astrocytes, glycogen accumulation, hippocampus, frontal cortex, cerebellar cortex, hypothalamus, midbrain reticular formation, synaptic density, neuronal activity, prolonged anesthesia
- MeSH terms
- Animals, Brain, Cerebellar Cortex, Cerebral Cortex, Glycogen, Histocytochemistry, Hypothalamus, Microscopy, Electron, Phenobarbital, Reticular Formation, Mice
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