Buprenorphine: Demonstration of physical dependence liability

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

Martin, W. R., Eades, C. G., Thompson, J. A., Huppler, R. E., & Gilbert, P. E. (1976) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)30536-7 · Cited by 2,992 · see citing works

Opiates and endogenous opioid peptides

Kelly, J. S., & Dingledine, R. J. (1977) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(77)90262-6 · Cited by 1,290 · see citing works

Human Pharmacology and Abuse Potential of the Analgesic Buprenorphine: A Potential Agent for Treating Narcotic Addiction

Jasinski, D. R. (1978) · Archives of General Psychiatry · doi:10.1001/archpsyc.1978.01770280111012 · Cited by 782 · see citing works

AGONIST AND ANTAGONIST PROPERTIES OF BUPRENORPHINE, A NEW ANTINOCICEPTIVE AGENT

Cowan, A., Lewis, J. W., & Macfarlane, I. R. (1977) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1977.tb07532.x · Cited by 529 · see citing works

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

Bl�sig, J., Herz, A., Reinhold, K., & Zieglg�nsberger, S. (1973) · Psychopharmacology · doi:10.1007/bf00428791 · Cited by 521 · see citing works

Buprenorphine suppresses heroin use by heroin addicts

Mello, N. K., & Mendelson, J. H. (1980) · Science · doi:10.1126/science.7352279 · Cited by 298 · see citing works

Formulation of a Morphine Implantation Pellet Suitable for Tolerance-Physical Dependence Studies in Mice

Gibson, R. D., & Tingstad, J. E. (1970) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600590338 · Cited by 222 · see citing works

Selective development of tolerance without dependence in multiple opiate receptors of mouse vas deferens

Schulz, R., Wüster, M., Krenss, H., & Herz, A. (1980) · Nature · doi:10.1038/285242a0 · Cited by 128 · see citing works

Animal and molecular pharmacology of mixed agonist‐antagonist analgesic drugs.

Rance, M. J. (1979) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1979.tb04701.x · Cited by 58 · see citing works

Schmerz. Grundlagen—Pharmakologie—Therapie.

(1972) · Annals of Internal Medicine · doi:10.7326/0003-4819-77-3-497_1 · Cited by 39 · see citing works

Mixed agonist‐antagonist opiates and physical dependence.

Jacob, J., Michaud, G., & Tremblay, E. C. (1979) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1979.tb04703.x · Cited by 36 · see citing works

Evaluation in nonhuman primates: evaluation of the physical dependence capacities of oripavine-thebaine partial agonists in patas monkeys.

Cowan, A. (1973) · PubMed · Cited by 35 · see citing works

Reinitiation of sensitivity to naloxone by a single narcotic injection in postaddicted mice.

Brase, D. A., Iwamoto, E. T., Loh, H. H., & Way, E. L. (1976) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)30511-2 · Cited by 30 · see citing works

In vivo opiate binding unchanged in tolerant/dependent mice

Dum, J., Meyer, G., Höllt, V., & Herz, A. (1979) · European Journal of Pharmacology · doi:10.1016/0014-2999(79)90316-9 · Cited by 27 · see citing works

Buprenorphine: A Unique Drug with Complex Pharmacology

Lutfy, K., & Cowan, A. (2004) · Current Neuropharmacology · doi:10.2174/1570159043359477 · Cited by 342 · see citing works

Buprenorphine: Considerations for Pain Management

Johnson, R. E., Fudala, P. J., & Payne, R. (2005) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2004.07.005 · Cited by 290 · see citing works

Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human

Morgan, M. M., & Christie, M. J. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01335.x · Cited by 273 · see citing works

A brain-centric model of suicidal behavior

Mann, J. J., & Rizk, M. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20081224 · Cited by 214 · see citing works

Buprenorphine-Induced Antinociception Is Mediated by μ-Opioid Receptors and Compromised by Concomitant Activation of Opioid Receptor-Like Receptors

Lutfy, K., Eitan, S., Bryant, C. D., Yang, Y. C., Saliminejad, N., Walwyn, W., Kieffer, B. L., Takeshima, H., Carroll, F. I., Maidment, N. T., et al. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-32-10331.2003 · Cited by 211 · see citing works

In vivo RECEPTOR BINDING OF THE OPIATE PARTIAL AGONIST, BUPRENORPHINE, CORRELATED WITH ITS AGONISTIC AND ANTAGONISTIC ACTIONS

Dum, J., & Herz, A. (1981) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1981.tb10473.x · Cited by 176 · see citing works

Buprenorphine detoxification from opiod dependence: A pilot study

Kosten, T. R., & Kleber, H. D. (1988) · Life Sciences · doi:10.1016/0024-3205(88)90454-7 · Cited by 112 · see citing works

Buprenorphine in the treatment of opioid dependence

Davids, E. (2003) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(03)00146-9 · Cited by 91 · see citing works

Treatment of Heroin Addicts Using Buprenorphine

Kosten, T. R., Morgan, C., & Kleber, H. D. (1991) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952999108992815 · Cited by 87 · see citing works

Differential tolerance to antinociceptive effects of µ opioids during repeated treatment with etonitazene, morphine, or buprenorphine in rats

Walker, E. A., & Young, A. M. (2001) · Psychopharmacology · doi:10.1007/s002130000620 · Cited by 78 · see citing works

Buprenorphine: An Analgesic with an Expanding Role in the Treatment of Opioid Addiction

Robinson, S. E. (2002) · CNS Drug Reviews · doi:10.1111/j.1527-3458.2002.tb00235.x · Cited by 78 · see citing works

Buprenorphine sublingual tablets: effects on IV heroin self-administration by humans

Comer, S. D., Collins, E. D., & Fischman, M. W. (2001) · Psychopharmacology · doi:10.1007/s002130000623 · Cited by 77 · see citing works

P300 assessment of opiate and cocaine users: Effects of detoxification and buprenorphine treatment

Kouri, E. M., Lukas, S. E., & Mendelson, J. H. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00468-8 · Cited by 73 · see citing works

Behavioral pharmacology of buprenorphine, with a focus on preclinical models of reward and addiction

Tzschentke, T. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1003-8 · Cited by 71 · see citing works

Buprenorphine: The Basic Pharmacology Revisited

Cowan, A. (2007) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e31806c9202 · Cited by 67 · see citing works

Delta opioid antagonist effects of buprenorphine in rhesus monkeys

Negus, S. S., Bidlack, J. M., Mello, N. K., Furness, M. S., Rice, K. C., & Brandt, M. R. (2002) · Behavioural Pharmacology · doi:10.1097/00008877-200211000-00005 · Cited by 64 · see citing works

Substitution and primary dependence studies in animals

Woods, J. H., & Gmerek, D. E. (1985) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(85)90059-6 · Cited by 60 · see citing works

Kappa antagonist properties of buprenorphine in non-tolerant and morphine-tolerant rats

Negus, S. S., Picker, M. J., & Dykstra, L. (1989) · Psychopharmacology · doi:10.1007/bf00442021 · Cited by 58 · see citing works

Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal

Wilson, L., Chakraborty, S., Eans, S. O., Cirino, T. J., Stacy, H. M., Simons, C. A., Uprety, R., Majumdar, S., & McLaughlin, J. P. (2021) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-01034-7 · Cited by 55 · see citing works

Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a κ Partial Agonist and μ Partial Agonist

Wang, Y., Chai, J., Xu, X., Ye, R.-F., Zan, G., Liu, G. Y.-K., Long, J.-D., Ma, Y., Huang, X., Xiao, Z., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-32568-y · Cited by 54 · see citing works

Experimental study of the morphine de-addiction properties of Delphinium denudatum Wall.

Rahman, S. Z., Khan, R. A., & Kumar, A. (2002) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-2-6 · Cited by 42 · see citing works

A Double Blind, within Subject Comparison of Spontaneous Opioid Withdrawal from Buprenorphine versus Morphine

Tompkins, D. A., Smith, M. T., Mintzer, M. Z., Campbell, C. M., & Strain, E. C. (2013) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.113.209478 · Cited by 40 · see citing works

Interactions between mu and kappa opioid agonists in the rat drug discrimination procedure

Negus, S. S., Picker, M. J., & Dykstra, L. A. (1990) · Psychopharmacology · doi:10.1007/bf02247126 · Cited by 39 · see citing works

Buprenorphine is an Antagonist at the ϰ Opioid Receptor

Richards, M. L., & Sadée, W. (1985) · Pharmaceutical Research · doi:10.1023/a:1016340106299 · Cited by 37 · see citing works

The antinociceptive efficacy of buprenorphine administered through the drinking water of rats

Jessen, L. R., Christensen, S. L., & Bjerrum, O. J. (2007) · Laboratory Animals · doi:10.1258/002367707780378131 · Cited by 36 · see citing works

Beta endorphin levels during heroin, methadone, buprenorphine, and naloxone challenges: Preliminary findings

Kosten, T. R., Morgan, C., & Kreek, M.-J. (1992) · Biological Psychiatry · doi:10.1016/0006-3223(92)90220-t · Cited by 35 · see citing works

Disposition in the rat of buprenorphine administered parenterally and as a subcutaneous implant

Pontani, R. B., Vadlamani, N. L., & Misra, A. L. (1985) · Xenobiotica · doi:10.3109/00498258509045363 · Cited by 32 · see citing works

Mood and affect during detoxification of opiate addicts: a comparison of buprenorphine versus methadone

Seifert, J., Metzner, C., Paetzold, W., Borsutzky, M., Ohlmeier, M. D., Passie, T., Hauser, U., Becker, H., Wiese, B., Emrich, H. M., et al. (2005) · Addiction Biology · doi:10.1080/13556210500123191 · Cited by 31 · see citing works

Expression of BDNF and TrkB Phosphorylation in the Rat Frontal Cortex During Morphine Withdrawal are NO Dependent

Peregud, D., Yakovlev, A. A., Stepanichev, M. Y., Onufriev, M. V., Panchenko, L. F., & Gulyaeva, N. V. (2015) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-015-0267-6 · Cited by 30 · see citing works

Buprenorphine-Containing Treatments

Robinson, S. E. (2006) · CNS Drugs · doi:10.2165/00023210-200620090-00001 · Cited by 28 · see citing works

Comparison of abuse, suspected suicidal intent, and fatalities related to the 7-day buprenorphine transdermal patch versus other opioid analgesics in the National Poison Data System

COPLAN, P. M., Sessler, N. E., Harikrishnan, V., Singh, R., & Perkel, C. (2016) · Postgraduate Medicine · doi:10.1080/00325481.2017.1269596 · Cited by 25 · see citing works

The clinical use of buprenorphine in opiate addiction: evidence and practice

Law, F. D., Myles, J. S., Daglish, M. R. C., & Nutt, D. (2004) · Acta Neuropsychiatrica · doi:10.1111/j.0924-2708.2004.00095.x · Cited by 22 · see citing works

Naloxone‐induced withdrawal in patients with buprenorphine dependence

NIGAM, A. K., SRIVASTAVA, R. P., Saxena, S., Chavan, B. S., & Sundaram, K. R. (1994) · Addiction · doi:10.1111/j.1360-0443.1994.tb00898.x · Cited by 23 · see citing works

Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model

Berke, M. S., Fensholdt, L. K. D., Hestehave, S., Kalliokoski, O., & Abelson, K. (2022) · PLoS ONE · doi:10.1371/journal.pone.0260356 · Cited by 18 · see citing works

Behavioral characterization of opioid mixed agonist-antagonists

Woods, J. H. (1987) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(87)90004-4 · Cited by 18 · see citing works

The effects of the acute administration of buprenorphine hydrochloride on the release of anterior pituitary hormones in the rat: Evidence for the involvement of multiple opiate receptors

Pechnick, R. N., George, R., & Poland, R. E. (1985) · Life Sciences · doi:10.1016/0024-3205(85)90002-5 · Cited by 18 · see citing works

Effects of morphine, naloxone, buprenorphine, butorphanol, haloperidol and imipramine on morphine withdrawal signs in cynomolgus monkeys

Fukase, H., Fukuzaki, K., Koja, T., Nagata, R., & Lukas, S. E. (1994) · Psychopharmacology · doi:10.1007/bf02247468 · Cited by 15 · see citing works

A long-acting buprenorphine delivery system

Pontani, R. B. (1983) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(83)90472-0 · Cited by 15 · see citing works

Reversibility of opioid receptor occupancy of buprenorphine in vivo

Englberger, W., Kögel, B. Y., Friderichs, E., Straβburger, W., & Germann, T. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.01.022 · Cited by 15 · see citing works

Neurobiological Adaptations to Psychostimulants and Opiates as a Basis of Treatment Development

Sevarino, K. A., Oliveto, A. H., & Kosten, T. R. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06676.x · Cited by 15 · see citing works

Onset of tolerance to discriminative stimulus effects of morphine

Young, A. M., Steigerwald, E. S., Makhay, M. M., & Kapitsopoulos, G. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90213-l · Cited by 15 · see citing works

Donepezil reverses buprenorphine-induced central respiratory depression in anesthetized rabbits

Sakuraba, S., Tsujita, M., Arisaka, H., Takeda, J., Yoshida, K.-I., & Kuwana, S. (2009) · Biological Research · doi:10.4067/s0716-97602009000400008 · Cited by 10 · see citing works

Buprenorphine prescription, misuse and service provision: a global perspective

Ho, R., Chen, K. Y., Broekman, B. F. P., & Mak, A. (2009) · Advances in Psychiatric Treatment · doi:10.1192/apt.bp.108.005975 · Cited by 8 · see citing works

Physiological dependence to mitragynine indicated by a rapid cross-dependence procedure with heroin-dependent mice

Yue, K., Katz, J. L., & Shu, X. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06080-1 · Cited by 7 · see citing works

Effects of buprenorphine on motility in chronically morphine treated rats

Bartoletti, M., Gaiardi, M., Gubellini, C., Bacchi, A., & Babbini, M. (1993) · Neuropharmacology · doi:10.1016/0028-3908(93)90141-o · Cited by 7 · see citing works

Buprenorphin (Temgesic®)—Pharmakologie und klinische Anwendung

Jurna, I. (1987) · Der Schmerz · doi:10.1007/bf02529121 · Cited by 7 · see citing works

MicroRNA may regulate the content of the brain-derived neurotrophic factor in the frontal cortex of rats after spontaneous morphine withdrawal

Peregud, D., Panchenko, L. F., & Gulyaeva, N. V. (2016) · Neurochemical Journal · doi:10.1134/s1819712416040085 · Cited by 6 · see citing works

Pharmacological properties of newly synthesized derivatives of (−)-6β-acetylthionormorphine and their interactions with opioid receptors

Takayanagi, I., Koike, K., & Suzuki, T. (1990) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(90)91004-b · Cited by 6 · see citing works

Pharmacology of Mixed NOP/Mu Ligands

Toll, L., Khroyan, T. V., Polgar, W. E., Husbands, S. M., & Zaveri, N. T. (2013) · ACS symposium series · doi:10.1021/bk-2013-1131.ch017 · Cited by 5 · see citing works

Stimulation of avoidance behavior by buprenorphine in rats

Shannon, H. E. (1983) · Psychopharmacology · doi:10.1007/bf00427487 · Cited by 5 · see citing works

Drug Abuse: Treatment and Management

Schifano, F. (2009) · doi:10.1002/9780470975084.ch3 · Cited by 4 · see citing works

Expression of the mRNA of neurotrophins in brain regions of rats after spontaneous morphine withdrawal

Peregud, D., Yakovlev, A. A., Panchenko, L. F., & Gulyaeva, N. V. (2011) · Neurochemical Journal · doi:10.1134/s181971241102005x · Cited by 1 · see citing works

A single compound alternative to a buprenorphine/naltrexone combination

Ridzwan, I. E. (2012) · The University of Bath Online Publications Store (The University of Bath) · Cited by 1 · see citing works

Buprenorphine for Opioid and Cocaine Dependence

Rosen, M. I., & Kosten, T. R. (1992) · Humana Press eBooks · doi:10.1007/978-1-4612-0359-9_7 · Cited by 1 · see citing works

Nitric oxide synthase activity and the level of nitrates/nitrites in brain regions during spontaneous morphine withdrawal in rats

Peregud, D., Onufriev, M. V., Yakovlev, A. A., Stepanichev, M. Y., Лазарева, Н. А., Pavlova, T. V., Панченко, Л. Ф., & Gulyaeva, N. V. (2007) · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry · doi:10.1134/s1990750807020047

Involvement of kappa opioid receptors in the neuroadaptation of rats to buprenorphine

Cowan, A. (1994) · Regulatory Peptides · doi:10.1016/0167-0115(94)90393-x

The antagonist analgesic concept

Lewis, J. W. (1982) · Springer eBooks · doi:10.1007/978-94-011-7457-2_4

Recent Advances in Detoxification and Maintenance Therapy

Best, S. E., Oliveto, A. H., & Kosten, T. R. (1996)

Opioids

Farrell, M., Larance, B., & Breen, C. L. (2020) · doi:10.1093/med/9780198713005.003.0051

The antagonist analgesic concept

Lewis, J. W. (1982) · Springer eBooks · doi:10.1007/978-94-011-7864-8_4

Physical dependence induced by opiate partial agonists in the rat

McCarthy, P. S., & Howlett, G. J. (1984) · Neuropeptides · doi:10.1016/0143-4179(84)90014-3 · Cited by 15 · see citing works

Buprenorphine's physical dependence potential: antagonist-precipitated withdrawal in humans.

Eissenberg, T., Greenwald, M. K., Johnson, R. E., Liebson, I. A., Bigelow, G. E., & Stitzer, M. L. (1996) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12294-5 · Cited by 79 · see citing works

Buprenorphine, morphine and naloxone effects during ascending morphine maintenance in humans.

Schuh, K. J., WALSH, S. L., Bigelow, G. E., Preston, K. L., & Stitzer, M. L. (1996) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20670-x · Cited by 41 · see citing works

The physical dependence liability of butorphanol: A comparative study with morphine

Horan, P. J., & Ho, I. K. (1991) · European Journal of Pharmacology · doi:10.1016/0014-2999(91)90895-w · Cited by 54 · see citing works

Rapid induction of dependence to morphine in rats

Leung, C. M. K., Dai, S., & Ogle, C. W. (1986) · Neuropharmacology · doi:10.1016/0028-3908(86)90256-x · Cited by 25 · see citing works