The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Inhibition of HIV replication by amino‐sugar derivatives
Open accessAbstract
The plant alkaloids castanospermine, dihydroxymethyldihydroxypyrrolidine and deoxynojirimycin have recently been shown to have potential anti‐HIV activity [(1987) Proc. Natl. Acad. Sci. USA 84, 8120–8124; (1987) Nature 330, 74–77; (1987) Lancet i, 1025–1026]. They are thought to act by inhibiting α‐glucosidase I, an enzyme involved in the processing of N‐linked oligosaccharides on glycoproteins. We report here the relative efficacy of a spectrum of amino‐sugar derivatives as inhibition of HIV cytopathicity. Several α‐glucosidase inhibitors and α‐fucosidase inhibitors were found to be active at concentrations which were non‐cytotoxic.
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Cites
β1-6 Branching of Asn-Linked Oligosaccharides Is Directly Associated with Metastasis
Dennis, J. W., Laferté, S., Waghorne, C., Breitman, M. L., & Kerbel, R. S. (1987) · Science · doi:10.1126/science.2953071 · Cited by 940
Gruters, R. A., Neefjes, J. J., Tersmette, M., de Goede, R. E. Y., Tulp, A., Huisman, H. G., Miedema, F., & Ploegh, H. L. (1987) · Nature · doi:10.1038/330074a0 · Cited by 578
Hohenschutz, L. D., Bell, E. A., Jewess, P. J., Leworthy, D. P., Pryce, R. J., Arnold, E., & Clardy, J. (1981) · Phytochemistry · doi:10.1016/0031-9422(81)85181-3 · Cited by 383
Sticher, O. (2008) · Natural Product Reports · doi:10.1039/b700306b · Cited by 377
Walker, B. D., Kowalski, M., Goh, W. C., Kozarsky, K., Krieger, M., Rosen, C., Rohrschneider, L., Haseltine, W. A., & Sodroski, J. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.22.8120 · Cited by 337
Fleet, G. W. J., Nicholas, S. J., Smith, P. W., Evans, S. V., Fellows, L. E., & Nash, R. J. (1985) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)98636-2 · Cited by 223
Self-citationDennis, J. W. (1986) · PubMed · Cited by 204
Glycosidase inhibition by plant alkaloids which are structural analogues of monosaccharides
Evans, S. V., Fellows, L. E., Shing, T. K. M., & Fleet, G. W. J. (1985) · Phytochemistry · doi:10.1016/s0031-9422(00)83099-x · Cited by 185
Self-citationHumphries, M. J., Matsumoto, K., White, S. L., & Olden, K. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.6.1752 · Cited by 184
HETTKAMP, H., LEGLER, G., & BAUSE, E. (1984) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1984.tb08253.x · Cited by 166
Cited by
Glycosylation in health and disease
Reily, C., Stewart, T. J., Renfrow, M. B., & Novak, J. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0129-4 · Cited by 2,075
Asano, N., Nash, R. J., Molyneux, R. J., & Fleet, G. W. J. (2000) · Tetrahedron: Asymmetry · doi:10.1016/s0957-4166(00)00113-0 · Cited by 1,015
Self-citationPolyhydroxylated alkaloids—Natural occurrence and therapeutic applications
Watson, A. A., Fleet, G. W. J., Asano, N., Molyneux, R. J., & Nash, R. J. (2001) · Phytochemistry · doi:10.1016/s0031-9422(00)00451-9 · Cited by 714
Exploitation of glycosylation in enveloped virus pathobiology
Watanabe, Y., Bowden, T. A., Wilson, I. A., & Crispin, M. (2019) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2019.05.012 · Cited by 482
Iminosugars past, present and future: Medicines for tomorrow
Horne, G., Wilson, F. X., Tinsley, J., Williams, D. H., & Storer, R. (2011) · Drug Discovery Today · doi:10.1016/j.drudis.2010.08.017 · Cited by 320
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Metadata
- Authors
- Fleet, G. W. J., Karpas, A., Dwek, R. A., Fellows, L. E., Tyms, A. S., Petursson, S., Namgoong, S. K., Ramsden, N. G., Smith, P. W., Son, J. C., Wilson, F., Witty, D. R., Jacob, G. S., & Rademacher, T. W.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1988-09-12
- Volume
- 237
- Issue
- 1-2
- Pages
- 128-132
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W1987775596
- Cited by
- 349
- References
- 20
- FWCI
- 14.77
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Fleet, G. W. J., Karpas, A., Dwek, R. A., Fellows, L. E., Tyms, A. S., Petursson, S., Namgoong, S. K., Ramsden, N. G., Smith, P. W., Son, J. C., Wilson, F., Witty, D. R., Jacob, G. S., & Rademacher, T. W. (1988). Inhibition of HIV replication by amino‐sugar derivatives. FEBS Letters. https://doi.org/10.1016/0014-5793(88)80185-6
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