The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
The effect of quercetin on cell cycle progression and growth of human gastric cancer cells
Abstract
Quercetin, a flavonoid, is found in many plants, including edible fruits and vegetables. We examined the effects on cell growth of human malignant cells derived from the gastrointestinal tract and on cell cycle progression. Quercetin markedly inhibited the growth of human gastric cancer cells and the IC 50 value was 32–55 μM. DNA synthesis was suppressed to 14% of the control level by the treatment with 70 μM quercetin for 2 days. Furthermore, quercetin blocked cell progression from the G 1 to the S phase.
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Markwell, M. A. K., Haas, S. M., Bieber, L. L., & Tolbert, N. E. (1978) · Analytical Biochemistry · doi:10.1016/0003-2697(78)90586-9 · Cited by 6,458
Brown, J. P. (1980) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(80)90029-9 · Cited by 576
Mutagenic Activity of Quercetin and Related Compounds
Bjeldanes, L. F., & Chang, G. W. (1977) · Science · doi:10.1126/science.327550 · Cited by 348
Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium aquilinum).
Pamukcu, A. M., Yalçiner, S., Hatcher, J. F., & Bryan, G. T. (1980) · PubMed · Cited by 265
Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test
Brown, J. P., & Dietrich, P. S. (1979) · Mutation Research/Genetic Toxicology · doi:10.1016/0165-1218(79)90083-1 · Cited by 234
Kato, R., Nakadate, T., Yamamoto, S., & Sugimura, T. (1983) · Carcinogenesis · doi:10.1093/carcin/4.10.1301 · Cited by 214
The effect of flavonoids on aerobic glycolysis and growth of tumor cells.
Suolinna, E.-M., Buchsbaum, R., & Racker, E. (1975) · PubMed · Cited by 210
Mutagenicity of flavone derivatives.
SUGIMURA, T., NAGAO, M., MATSUSHIMA, T., YAHAGI, T., SEINO, Y., SHIRAI, A., SAWAMURA, M., NATORI, S., YOSHIHIRA, K., FUKUOKA, M., et al. (1977) · Proceedings of the Japan Academy, Series B · doi:10.2183/pjab.53.194 · Cited by 191
Carcinogenicity examination of quercetin and rutin in ACI rats
Hirono, I., Ueno, I., Hosaka, S., Takanashi, H., Matsushima, T., Sugimura, T., & Natori, S. (1981) · Cancer Letters · doi:10.1016/0304-3835(81)90081-1 · Cited by 173
Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration
Morino, K., Matsukura, N., Kawachi, T., Ohgaki, H., Sügimura, T., & Hirono, I. (1982) · Carcinogenesis · doi:10.1093/carcin/3.1.93 · Cited by 145
Cited by
Middleton, E., Kandaswami, C., & Theoharides, T. C. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01472-8 · Cited by 4,882
Tannins and Human Health: A Review
Chung, K.-T., Wong, T. Y., Wei, C.-I., Huang, Y.-W., & Lin, Y. (1998) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408699891274273 · Cited by 1,996
Antioxidant Compounds and Their Antioxidant Mechanism
Francenia Santos-Sánchez, N., Salas-Coronado, R., Villanueva-Cañongo, C., & Hernández-Carlos, B. (2019) · Antioxidants · doi:10.5772/intechopen.85270 · Cited by 594
Lu, J., Papp, L. V., Fang, J., Rodriguez-Nieto, S., Zhivotovsky, B., & Holmgren, A. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3310 · Cited by 326
Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells
Vafadar, A., Shabaninejad, Z., Movahedpour, A., Fallahi, F., Taghavipour, M., Ghasemi, Y., Akbari, M., Shafiee, A., Hajighadimi, S., Moradizarmehri, S., et al. (2020) · Cell & Bioscience · doi:10.1186/s13578-020-00397-0 · Cited by 296
Metadata
- Authors
- Yoshida, M., Sakai, T., Hosokawa, N., Marui, N., Matsumoto, K., Fujioka, A., Nishino, H., & Aoike, A.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1990-01-15
- Volume
- 260
- Issue
- 1
- Pages
- 10-13
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2014231457
- Cited by
- 317
- References
- 15
- FWCI
- 5.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yoshida, M., Sakai, T., Hosokawa, N., Marui, N., Matsumoto, K., Fujioka, A., Nishino, H., & Aoike, A. (1990). The effect of quercetin on cell cycle progression and growth of human gastric cancer cells. FEBS Letters. https://doi.org/10.1016/0014-5793(90)80053-l
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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