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Cited by 630

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Widespread tissue distribution, species distribution and changes in activity of Ca2+‐dependent and Ca2+‐independent nitric oxide synthases

Salter, Mark, Knowles, Richard G., Moncada, Salvador·1991·FEBS Letters

Abstract

The distribution of Ca 2+‐dependent and Ca 2+‐independent nitric oxide synthase (NOS) was studied in rabbits and in control and endotoxin‐treated rats and guinea‐pigs. There was a widespread localization of NOS which differed for the two forms of the enzyme and which showed marked differences between species. Endotoxin induced the activity of the Ca 2+‐independent NOS in many tissues and also increased the activity of Ca 2+‐dependent NOS in the rat ileum and caecum. These results demonstrate the differential distribution of NOSs in control and endotoxin‐treated animals and emphasize the widespread biological role of nitric oxide (NO).

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Metadata

Authors
Salter, M., Knowles, R. G., & Moncada, S.
Venue
FEBS Letters
Publisher
Wiley
Published
1991-10-07
Volume
291
Issue
1
Pages
145-149
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
OpenAlex
W1973535328
Cited by
630
References
1
FWCI
20.59
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Widespread tissue distribution, species distribution and changes in activity of Ca2+‐dependent and Ca2+‐independent nitric oxide synthases. https://app.cochat.ai/papers/10.1016/0014-5793(91)81123-p
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Salter, M., Knowles, R. G., & Moncada, S. (1991). Widespread tissue distribution, species distribution and changes in activity of Ca2+‐dependent and Ca2+‐independent nitric oxide synthases. FEBS Letters. https://doi.org/10.1016/0014-5793(91)81123-p

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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