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Cited by 169

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise

Open access
Sandri, Marco, Carraro, Ugo, Podhorska-Okolov, Marzena, Rizzi, Corrado, Arslan, Paola, Monti, Daniela, Franceschi, Claudio·1995·FEBS Letters

Abstract

The current view indicates that after eccentric exercise myofibers are mechanically damaged and therefore an inflammatory and necrotic process occurs. In the present paper we examine the possibility that apoptosis plays a role in normal and dystrophin‐deficient muscles after running. We analysed for apoptosis normal and dystrophin‐deficient mouse muscles after a night of spontaneous wheel‐running followed by two days of rest. Terminal deoxynucleotidyl transferase‐mediated endlabeling of DNA in nuclei in tissue sections and gel electrophoresis of extracted DNA showed the presence of fragmented DNA. Furthermore, ubiquitin, a protein whose appearance is related to apoptosis, increased in muscles of both dystrophic and normal runner mice. The present findings which confirm that DNA damage is absent in muscles of sedentary mice but present in muscles of runner mice offer a new hypothesis on early events of muscle damage.

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Crossref · 10.1016/0014-5793(95)00908-r

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Metadata

Authors
Sandri, M., Carraro, U., Podhorska-Okolov, M., Rizzi, C., Arslan, P., Monti, D., & Franceschi, C.
Venue
FEBS Letters
Publisher
Wiley
Published
1995-10-16
Volume
373
Issue
3
Pages
291-295
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
OpenAlex
W1969683520
Cited by
169
References
2
FWCI
2.72
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise. https://app.cochat.ai/papers/10.1016/0014-5793(95)00908-r
The paper
Sandri, M., Carraro, U., Podhorska-Okolov, M., Rizzi, C., Arslan, P., Monti, D., & Franceschi, C. (1995). Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise. FEBS Letters. https://doi.org/10.1016/0014-5793(95)00908-r

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