Cited by 462Food composition and propertiesGastrointestinal motility and disordersNutritional Studies and Diet

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Fecal weight, colon cancer risk, and dietary intake of nonstarch polysaccharides (dietary fiber)

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Cummings, John H., Bingham, Sheila A., Heaton, Kenneth W., Eastwood, Martin A.·1992·Gastroenterology

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Abstract

Low fecal weight and slow bowel transit time are thought to be associated with bowel cancer risk, but few published data defining bowel habits in different communities exist. Therefore, data on stool weight were collected from 20 populations in 12 countries to define this risk more accurately, and the relationship between stool weight and dietary intake of nonstarch polysaccharides (NSP) (dietary fiber) was quantified. In 220 healthy U.K. adults undertaking careful fecal collections, median daily stool weight was 106 g/day (men, 104 g/day; women, 99 g/day; P = 0.02) and whole-gut transit time was 60 hours (men, 55 hours; women, 72 hours; P = 0.05); 17% of women, but only 1% of men, passed < 50 g stool/day. Data from other populations of the world show average stool weight to vary from 72 to 470 g/day and to be inversely related to colon cancer risk (r = -0.78). Meta-analysis of 11 studies in which daily fecal weight was measured accurately in 26 groups of people (n = 206) on controlled diets of known NSP content shows a significant correlation between fiber intake and mean daily stool weight (r = 0.84). Stool weight in many Westernized populations is low (80-120 g/day), and this is associated with increased colon cancer risk. Fecal output is increased by dietary NSP. Diets characterized by high NSP intake (approximately 18 g/day) are associated with stool weights of 150 g/day and should reduce the risk of bowel cancer.

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Cancer Incidence in Five Continents
Doll, R., Muir, C. S., & Waterhouse, J. A. H. (1970) · Springer eBooks · doi:10.1007/978-3-642-85851-2 · Cited by 8,485
Diet, Nutrition, and the Prevention of Chronic Diseases
Zimmermann, M. B. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/60.4.644a · Cited by 2,131
EFFECT OF DIETARY FIBRE ON STOOLS AND TRANSIT-TIMES, AND ITS ROLE IN THE CAUSATION OF DISEASE
Burkitt, D. P., Walker, A. R. P., & Painter, N. S. (1972) · The Lancet · doi:10.1016/s0140-6736(72)92974-1 · Cited by 1,033
Dietary fibre, transit-time, faecal bacteria, steroids, and colon cancer in two Scandinavian populations. Report from the International Agency for Research on Cancer Intestinal Microecology Group.
MacLennan, R., & Jensen, O. M. (1977) · PubMed · Cited by 685
Dietary Fiber, Vegetables, and Colon Cancer: Critical Review and Meta-analyses of the Epidemiologic Evidence
Trock, B. J., Lanza, E., & Greenwald, P. (1990) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/82.8.650 · Cited by 548
Mechanism of action of dietary fibre in the human colon
Stephen, A. M., & Cummings, J. H. (1980) · Nature · doi:10.1038/284283a0 · Cited by 503
Self-citation
Improved Method for Measurement of Dietary Fiber as Non-Starch Polysaccharides in Plant Foods
Englyst, H. N., & Cummings, J. H. (1988) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/71.4.808 · Cited by 415
Self-citation
COLONIC RESPONSE TO DIETARY FIBRE FROM CARROT, CABBAGE, APPLE, BRAN, AND GUAR GUM
Cummings, J. H., Branch, W. J., Jenkins, D. J. A., Southgate, D. A. T., Houston, H., & James, W. P. T. (1978) · The Lancet · doi:10.1016/s0140-6736(78)90357-4 · Cited by 406
Self-citation
Cancer: causes, occurrence and control
(1991) · Choice Reviews Online · doi:10.5860/choice.29-0340 · Cited by 333
Urine nitrogen as an independent validatory measure of dietary intake: a study of nitrogen balance in individuals consuming their normal diet
Bingham, S., & Cummings, J. (1985) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/42.6.1276 · Cited by 289
Self-citation

Show all 52 references

Research works printed but not linked: 5

Pomare, 1981, Dietary fibre intake, stool weight and intestinal transit in four South Pacific populations (abstr), Aust NZ J Med, 11, 221
Tarida, 1984, Faecal bile acids in adenomatous polyps, Gut, 25, 824
1982, Diet and large bowel cancer in Denmark and Finland, Nutr Cancer, 4, 1
1977, Dietary fibre, transit time, faecal bacteria, steroids, and colon cancer in two Scandinavian populations, Lancet, 2, 207
Cummings, 1992, Laxative properties of resistant starches (abstr), Gastroenterology, 102, A548

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Wang, L., Li, X., & Chen, Z. (2008) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2008.12.006 · Cited by 98
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Evidence for the ambiguity of the term constipation: the role of irritable bowel syndrome.
Probert, C. S., Emmett, P. M., Cripps, H. A., & Heaton, K. W. (1994) · Gut · doi:10.1136/gut.35.10.1455 · Cited by 76
Self-citation
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Behavioural, attitudinal and dietary responses to the consumption of wholegrain foods
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Evans, R. C., Fear, S. C., Ashby, D., Hackett, A., Williams, E. M. I., van der Vliet, M., Dunstan, F., & Rhodes, J. M. (2002) · Gastroenterology · doi:10.1053/gast.2002.33659 · Cited by 64
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Bird, A. R., López‐Rubio, A., Shrestha, A. K., & Gidley, M. J. (2009) · Elsevier eBooks · doi:10.1016/b978-0-12-374195-0.00014-8 · Cited by 59
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Soergel, K. H. (1994) · Journal of Molecular Medicine · doi:10.1007/bf00180540 · Cited by 60
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The site-specific delivery of ursodeoxycholic acid to the rat colon by sulfate conjugation
Rodrigues, C. M. P., Kren, B. T., Steer, C. J., & Setchell, K. D. R. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90750-5 · Cited by 59
Different dietary fibre sources and risks of colorectal cancer and adenoma: a dose–response meta-analysis of prospective studies
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Self-citation
Prebiotics and human health: The state-of-the-art and future perspectives
Conway, P. L. (2001) · Näringsforskning · doi:10.3402/fnr.v45i0.1784 · Cited by 58
Defecation Frequency and Stool Form in a Coastal Eastern Indian Population
Panigrahi, M. K., Kar, S. K., Singh, S. P., & Ghoshal, U. C. (2013) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2013.19.3.374 · Cited by 56
Randomised clinical study: inulin short‐chain fatty acid esters for targeted delivery of short‐chain fatty acids to the human colon
Polyviou, T. P., MacDougall, K., Chambers, E. S., Viardot, A., Psichas, A., Jawaid, S., Harris, H. C., Edwards, C. A., Simpson, L., Murphy, K. G., et al. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13749 · Cited by 59
Relationship between lifestyle factors and defecation in a Japanese population
Nakaji, S., Tokunaga, S., Sakamoto, J., Todate, M., Shimoyama, T., Umeda, T., & Sugawara, K. (2002) · European Journal of Nutrition · doi:10.1007/s00394-002-0380-4 · Cited by 55
Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial
Fechner, A., Fenske, K., & Jahreis, G. (2013) · Nutrition Journal · doi:10.1186/1475-2891-12-101 · Cited by 55
Effects of the type and level of dietary fibre supplements on nitrogen retention and excretion patterns
Tetens, I., Livesey, G., & Eggum, B. O. (1996) · British Journal Of Nutrition · doi:10.1079/bjn19960147 · Cited by 55
Dietary Fibre and Gastrointestinal Function
Schneeman, B. O. (2000) · doi:10.1002/9780470999615.ch14 · Cited by 55
A survey of β‐glucan and arabinoxylan content in wheat
Pritchard, J. R., Lawrence, G. J., Larroque, O., Li, Z., Laidlaw, H. K., Morell, M. K., & Rahman, S. (2011) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4316 · Cited by 53
The Human Colonic Microbiota
Macfarlane, G. T., & McBain, A. J. (1999) · Springer eBooks · doi:10.1007/978-94-017-1079-4_1 · Cited by 53
Acquisition, Evolution and Maintenance of the Normal Gut Microbiota
Macfarlane, G. T., & Macfarlane, L. E. (2009) · Digestive Diseases · doi:10.1159/000268127 · Cited by 57
Purification and identification of a novel heteropolysaccharide RBPS2a with anti-complementary activity from defatted rice bran
Wang, L., Zhang, H., Zhang, X., & Chen, Z. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.01.041 · Cited by 53
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Hughes, R., Pollock, J. R. A., & Bingham, S. A. (2002) · Nutrition and Cancer · doi:10.1207/s15327914nc421_10 · Cited by 52
Self-citation
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van Munster, I. P., & Nagengast, F. M. (1993) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529309101581 · Cited by 51
Beyond the Calories—Is the Problem in the Processing?
Laster, J., & Frame, L. A. (2019) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-019-00246-1 · Cited by 53
Calcium Supplementation Modifies the Relative Amounts of Bile Acids in Bile and Affects Key Aspects of Human Colon Physiology
Lupton, J. R., Steinbach, G., Chang, W., O'Brien, B. C., Wiese, S., Stoltzfus, C. L., Glober, G. A., Wargovich, M. J., McPherson, R. S., & Winn, R. J. (1996) · Journal of Nutrition · doi:10.1093/jn/126.5.1421 · Cited by 49
Nutrition and Gastrointestinal Disease
O’Keefe, S. J. (1996) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529609094750 · Cited by 48
Resistant Starch Content and Structural Changes in Maize (Zea mays) Tortillas During Storage
García‐Rosas, M., Bello‐Pérez, L. A., Yee-Madeira, H. T., Ramos, G., Flores-Morales, A., & Mora‐Escobedo, R. (2009) · Starch - Stärke · doi:10.1002/star.200800147 · Cited by 47
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Helsby, N. A., Zhu, S., Pearson, A. E., Tingle, M. D., & Ferguson, L. R. (2000) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(00)00101-9 · Cited by 47
Lower serum oestrogen concentrations associated with faster intestinal transit
Lewis, S., Heaton, K. W., OAKEY, R. E., & McGARRIGLE, H. H. G. (1997) · British Journal of Cancer · doi:10.1038/bjc.1997.397 · Cited by 47
Self-citation
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Wang, L., Huang, H., Wei, Y., Li, X., & Chen, Z. (2009) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2009.06.006 · Cited by 46
Effects of Olestra and Sorbitol Consumption on Objective Measures of Diarrhea: Impact of Stool Viscosity on Common Gastrointestinal Symptoms
McRorie, J. W., Zorich, N. L., Riccardi, K. A., Bishop, L. J., Filloon, T. G., Wason, S., & Giannella, R. A. (2000) · Regulatory Toxicology and Pharmacology · doi:10.1006/rtph.1999.1368 · Cited by 46
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Self-citation
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Ihara, E., Manabe, N., Ohkubo, H., Ogasawara, N., Ogino, H., Kakimoto, K., Kanazawa, M., Kawahara, H., Kusano, C., Kuribayashi, S., et al. (2024) · Digestion · doi:10.1159/000540912 · Cited by 60
Validation with biological markers for food intake of a dietary assessment method used by Swedish women with three different with dietary preferences
Johansson, G. K., Åkesson, A., Berglund, M., Nermell, B., & Vahter, M. (1998) · Public Health Nutrition · doi:10.1079/phn19980031 · Cited by 44
Non–digestible oligosaccharides and defense functions: lessons learned from animal models
Buddington, R. K., Kelly-Quagliana, K., Buddington, K. K., & Kimura, Y. (2002) · British Journal Of Nutrition · doi:10.1079/bjn/2002542 · Cited by 44
Modulation of fecal markers relevant to colon cancer risk: a high-starch Chinese diet did not generate expected beneficial changes relative to a Western-type diet
Muir, J. G., Walker, K. Z., Kaimakamis, M. A., Cameron, M. A., Govers, M. J., Lu, Z. X., Young, G. P., & ’Dea, K. O. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/68.2.372 · Cited by 44
Radioimmunodetection of solid tumors. Future horizons and applications for radioimmunotherapy
McKearn, T. J. (1993) · Cancer · doi:10.1002/1097-0142(19930615)71:12+ · Cited by 19
Polydextrose and soluble corn fiber increase five-day fecal wet weight in healthy men and women.
Timm, D., Thomas, W., Boileau, T., Williamson-Hughes, P. S., & Slavin, J. (2013) · Journal of NutriLife · doi:10.3945/jn.112.170118 · Cited by 41
The effect of prunes on stool output, gut transit time and gastrointestinal microbiota: A randomised controlled trial
Lever, E., Scott, S. M., Louis, P., Emery, P. W., & Whelan, K. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.01.003 · Cited by 45
Non–digestible oligosaccharides and defense functions: lessons learned from animal models
Buddington, R. K., Kelly-Quagliana, K., Buddington, K. K., & Kimura, Y. (2002) · British Journal Of Nutrition · doi:10.1079/bjnbjn/2002542 · Cited by 43
Pharmacological Approaches for the Treatment of Obesity
Fern??ndez-L??pez, J.-A., Remesar, X., Foz, M., & Alemany, M. (2002) · Drugs · doi:10.2165/00003495-200262060-00005 · Cited by 42
Effect of short‐chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco‐2
Fu, H., Shi, Y. Q., & Shan Jin, M. O. (2004) · Chinese Journal of Digestive Diseases · doi:10.1111/j.1443-9573.2004.00167.x · Cited by 42
Lactobacillus gasseri Gasser AM63T degrades oxalate in a multistage continuous culture simulator of the human colonic microbiota
Lewanika, T. R., Reid, S. J., Abratt, V. R., Macfarlane, G. T., & Macfarlane, S. (2007) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2007.00327.x · Cited by 42
Dietary fiber and colorectal neoplasia
Sengupta, S., Tjandra, J. J., & Gibson, P. R. (2001) · Diseases of the Colon & Rectum · doi:10.1007/bf02235491 · Cited by 41
Dietary Fiber and the Relationship to Chronic Diseases
Timm, D. A., & Slavin, J. L. (2008) · American Journal of Lifestyle Medicine · doi:10.1177/1559827608314149 · Cited by 41
Comparison of the nutritional effects of fructo-oligosaccharides of different sugar chain length in rats
Ohta, A., Ohtsuki, M., Baba, S., Hirayama, M., & Adachi, T. (1998) · Nutrition Research · doi:10.1016/s0271-5317(97)00205-4 · Cited by 41
Strong correlation between diet and development of colorectal cancer
Vita, M. D. (2012) · Frontiers in bioscience · doi:10.2741/4095 · Cited by 41
M-RTLV agar, a novel selective medium to distinguish Lactobacillus casei and Lactobacillus paracasei from Lactobacillus rhamnosus
Sakai, T., Oishi, K., Asahara, T., Takada, T., Yuki, N., Matsumoto, K., Nomoto, K., & Kushiro, A. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.03.019 · Cited by 39
Legume Flour or Bran: Sustainable, Fiber-Rich Ingredients for Extruded Snacks?
Proserpio, C., Bresciani, A., Marti, A., & Pagliarini, E. (2020) · Foods · doi:10.3390/foods9111680 · Cited by 44
RETRACTED: Anti-cancer effects of polyphenol-rich sugarcane extract
Prakash, M. D., Stojanovska, L., Feehan, J., Nurgali, K., Donald, E. L., Plebanski, M., Flavel, M., Kitchen, B., & Apostolopoulos, V. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247492 · Cited by 42
Retracted
In vitro maintenance of a human proximal colon microbiota using the continuous fermentation system P-ECSIM
Feria-Gervasio, D., Denis, S., Alric, M., & Brugère, J. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3462-5 · Cited by 41
A theoretical approach to using faecal indicator data to model norovirus concentration in surface water for QMRA: Glomma River, Norway
Petterson, S. R., Stenström, T. A., & Ottoson, J. R. (2015) · Water Research · doi:10.1016/j.watres.2015.12.037 · Cited by 37
Emergent evolutionary forces in spatial models of luminal growth and their application to the human gut microbiota
Ghosh, O. M., & Good, B. H. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2114931119 · Cited by 38
Short Term (14 Days) Consumption of Insoluble Wheat Bran Fibre-Containing Breakfast Cereals Improves Subjective Digestive Feelings, General Wellbeing and Bowel Function in a Dose Dependent Manner
Lawton, C. L., Walton, J., Hoyland, A., Howarth, E., Allan, P., Chesters, D., & Dye, L. (2013) · Nutrients · doi:10.3390/nu5041436 · Cited by 37
Value of a tomato byproduct as a source of dietary fiber in rats
Alvarado, A., Pacheco-Delahaye, E., & Hevia, P. (2001) · Plant Foods for Human Nutrition · doi:10.1023/a:1011855316778 · Cited by 37
Diet and cardiovascular disease in the UK: are the messages getting across?
Kelly, C. N. M., & Stanner, S. A. (2003) · Proceedings of The Nutrition Society · doi:10.1079/pns2003272 · Cited by 38
Microencapsulation of Menhaden Fish Oil Containing Soluble Rice Bran Fiber Using Spray Drying Technology
Wan, Y., Bankston, J. D., Bechtel, P. J., & Sathivel, S. (2011) · Journal of Food Science · doi:10.1111/j.1750-3841.2011.02111.x · Cited by 35
Faecal phytic acid and its relation to other putative markers of risk for colorectal cancer.
Owen, R. W., Weisgerber, U. M., Spiegelhalder, B., & Bartsch, H. (1996) · Gut · doi:10.1136/gut.38.4.591 · Cited by 35
Glacial Transport of Human Waste and Survival of Fecal Bacteria on Mt. McKinley’s Kahiltna Glacier, Denali National Park, Alaska
Goodwin, K., Loso, M. G., & Braun, M. (2012) · Arctic Antarctic and Alpine Research · doi:10.1657/1938-4246-44.4.432 · Cited by 33
Effects of isomalt consumption on gastrointestinal and metabolic parameters in healthy volunteers
Gostner, A., Schäffer, V., Theis, S., Menzel, T., Lührs, H., Melcher, R., Schauber, J., Kudlich, T., Dusel, G., Dorbath, D., et al. (2005) · British Journal Of Nutrition · doi:10.1079/bjn20051510 · Cited by 33

Authors: Cummings, J. H., Bingham, S. A., Heaton, K. W., & Eastwood, M. A.
Affiliations: University of Wisconsin–Madison (US)
ORCID: Cummings, John H.
Venue: Gastroenterology
Publisher: Elsevier BV
Published: 1992-12
Volume: 103
Issue: 6
Pages: 1783-1789
ISSN: 0016-5085 (ISSN-L)
DOI: 10.1016/0016-5085(92)91435-7
OpenAlex: W1962918087
Cited by: 462
References: 52
Citations by year: 2026: 6 · 2025: 4 · 2024: 11 · 2023: 11 · 2022: 14 · 2021: 13 · 2020: 9 · 2019: 18 · 2018: 11 · 2017: 8 · 2016: 15 · 2015: 10 · 2014: 16 · 2013: 14 · 2012: 19
FWCI: 8.19
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Gastroenterology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords: fecal weight, colon cancer risk, non-starch polysaccharides, dietary fiber, bowel transit time, whole gut transit time, bowel habits, stool output, Western diet, cancer prevention
MeSH terms: Adolescent, Adult, Aged, Colonic Neoplasms, Constipation, Dietary Fiber, Feces, Female, Gastrointestinal Transit, Humans, Male, Middle Aged, Risk, Sex Factors

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Fecal weight, colon cancer risk, and dietary intake of nonstarch polysaccharides (dietary fiber)

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