Cited by 198T-cell and Retrovirus StudiesHIV Research and TreatmentVirus-based gene therapy research

The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.

Sequence and spacing requirements of a retrovirus integration site

Open access

Colicelli, John, Goff, Stephen P.·1988·Journal of Molecular Biology

Open this paper in CoChat — free account

Abstract

Following infection, retroviruses insert a DNA copy of their RNA genome into the host cell genome. This integrative recombination reaction occurs at specific sites on the viral DNA: inverted repeat sequences near the termini of the linear DNA form of the viral genome. We have described elsewhere the generation and analysis of deletion mutations at one of the inverted repeat sequences in Moloney murine leukemia virus. We describe here the effects of insertion mutations made at this locus. Our results show that substantial sequence changes at the site of recombination can be tolerated, and that the spacing between the cleavage sites on the viral DNA can be expanded as well as contracted while still allowing efficient viral integration. After several rounds of virus replication, each of the insertion mutants gave rise to pseudorevertants with new alterations at the integration site.

Integrity signals

Registry

Crossref · 10.1016/0022-2836(88)90378-6

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

[57] Sequencing end-labeled DNA with base-specific chemical cleavages
Maxam, A. M., & Gilbert, W. (1980) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(80)65059-9 · Cited by 13,943
A rapid boiling method for the preparation of bacterial plasmids
Holmes, D. S., & Quigley, M. E. (1981) · Analytical Biochemistry · doi:10.1016/0003-2697(81)90473-5 · Cited by 3,198
Calcium-dependent bacteriophage DNA infection
Mandel, M., & Higa, A. (1970) · Journal of Molecular Biology · doi:10.1016/0022-2836(70)90051-3 · Cited by 2,521
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus
TEMIN, H. M., & MIZUTANI, S. (1970) · Nature · doi:10.1038/2261211a0 · Cited by 2,128
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses
BALTIMORE, D. (1970) · Nature · doi:10.1038/2261209a0 · Cited by 2,068
Transformation of mammalian cells with genes from procaryotes and eucaryotes
Wigler, M. H., Sweet, R. W., Sim, G.-K., Wold, B. J., Pellicer, À., Lacy, E., Maniatis, T., Silverstein, S. J., & Axel, R. (1979) · Cell · doi:10.1016/0092-8674(79)90093-x · Cited by 1,407
Nucleotide sequence of Moloney murine leukaemia virus
Shinnick, T. M., Lerner, R. A., & Sutcliffe, J. G. (1981) · Nature · doi:10.1038/293543a0 · Cited by 1,057
Enhancement of the Infectivity of Simian Virus 40 Deoxyribonucleic Acid With Diethylaminoethyl-Dextran 2
McCutchan, J. H., & Pagano, J. S. (1968) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/41.2.351 · Cited by 775
A detailed model of reverse transcription and tests of crucial aspects
Gilboa, E., Mitra, S. W., Goff, S., & Baltimore, D. (1979) · Cell · doi:10.1016/0092-8674(79)90357-x · Cited by 612
Self-citation
Mobile Genetic Elements
Mueller, R. F. (1984) · Journal of Medical Genetics · doi:10.1136/jmg.21.1.79 · Cited by 583

Show all 51 references

Research works printed but not linked: 13

Dhar, 1980, 77, 3937
Donehower, 1984, 81, 6461
Hughes, 1981, 78, 4299
Kriegler, 1983, Mol. Cell. Biol, 3, 325
Lobel, 1984, 81, 4149
Luciw, 1984, Mol. Cell. Biol, 4, 1260
McCutchan, 1968, J. Nat. Cancer Inst, 41, 351
Panganiban, 1984, 81, 7885
Prasad, 1986, Mol. Cell. Biol, 6, 4329
Senecoff, 1985, 82, 7270
Shoemaker, 1980, 77, 3932
Southern, 1982, J. Mol. Appl. Genet, 1, 327
Swanstrom, 1981, 78, 124

Sorted by citations

Retroviruses
Varmus, H. E. (1988) · Science · doi:10.1126/science.3287617 · Cited by 522
HIV-1 Reverse TranscriptionPreprint
Hu, W.-S., & Hughes, S. H. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006882 · Cited by 597
The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro
Craigie, R., Fujiwara, T., & Bushman, F. (1990) · Cell · doi:10.1016/0092-8674(90)90126-y · Cited by 409
Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA
Bushman, F. D., & Craigie, R. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.4.1339 · Cited by 410
Retroviral integrase domains: DNA binding and the recognition of LTR sequences
Khan, E., Mack, J. P. G., Katz, R. A., Kulkosky, J., & Skalka, A. M. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.4.851 · Cited by 287
Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence
Roth, M. J., Schwartzberg, P. L., & Goff, S. P. (1989) · Cell · doi:10.1016/0092-8674(89)90401-7 · Cited by 263
Self-citation
Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein
Méric, C., & Goff, S. P. (1989) · Journal of Virology · doi:10.1128/jvi.63.4.1558-1568.1989 · Cited by 255
Self-citation
GENETICS OF RETROVIRAL INTEGRATION
Goff, S. P. (1992) · Annual Review of Genetics · doi:10.1146/annurev.ge.26.120192.002523 · Cited by 224
Self-citation
Tn552, a novel transposable element from Staphylococcus aureus
Rowland, S., & Dyke, K. G. H. (1990) · Molecular Microbiology · doi:10.1111/j.1365-2958.1990.tb00669.x · Cited by 224
Retroviral nucleocapsid domains mediate the specific recognition of genomic viral RNAs by chimeric Gag polyproteins during RNA packaging in vivo
Berkowitz, R., Ohagen, A., Höglund, S., & Goff, S. (1995) · Journal of Virology · doi:10.1128/jvi.69.10.6445-6456.1995 · Cited by 215
Self-citation
Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro.
Leavitt, A. D., Shiue, L., & VARMUS, H. E. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53969-7 · Cited by 200
Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses.
Göttlinger, H. G., Dorfman, T., Cohen, É. A., & Haseltine, W. A. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.15.7381 · Cited by 192
Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations
Vincent, K. A., Ellison, V., Chow, S. A., & Brown, P. O. (1993) · Journal of Virology · doi:10.1128/jvi.67.1.425-437.1993 · Cited by 185
In Vivo Analysis of Retroviral Integrase Structure and Function
Engelman, A. (1999) · Advances in Virus Research · doi:10.1016/s0065-3527(08)60309-7 · Cited by 176
Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA recognition sequence for efficient cleavage
Vink, C., van Gent, D. C., Elgersma, Y., & Plasterk, R. H. A. (1991) · Journal of Virology · doi:10.1128/jvi.65.9.4636-4644.1991 · Cited by 181
Coupled Integration of Human Immunodeficiency Virus Type 1 cDNA Ends by Purified Integrase In Vitro: Stimulation by the Viral Nucleocapsid Protein
Carteau, S., Gorelick, R. J., & Bushman, F. D. (1999) · Journal of Virology · doi:10.1128/jvi.73.8.6670-6679.1999 · Cited by 180
Strand transfer inhibitors of HIV-1 integrase: bringing IN a new era of antiretroviral therapy.
Mccoll, D., & Chen, X.-W. (2010) · Antiviral Research · doi:10.1016/j.antiviral.2009.11.004 · Cited by 187
Mutations altering the Moloney murine leukemia virus p12 Gag protein affect virion production and early events of the virus life cycle
Yuan, B., Li, X.-Q., & Goff, S. (1999) · EMBO Journal · doi:10.1093/emboj/18.17.4700 · Cited by 164
Self-citation
Integration of Retroviral DNA
Brown, P. O. (1990) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-75218-6_2 · Cited by 163
Infectivity of Moloney Murine Leukemia Virus Defective in Late Assembly Events Is Restored by Late Assembly Domains of Other Retroviruses
Yuan, B., Campbell, S., Bacharach, E., Rein, A. R., & Goff, S. P. (2000) · Journal of Virology · doi:10.1128/jvi.74.16.7250-7260.2000 · Cited by 156
Self-citation
Genetic analysis of human immunodeficiency virus type 1 integrase and the U3 att site: unusual phenotype of mutants in the zinc finger-like domain
Masuda, T., Planelles, V, Krogstad, P., & Chen, I. S. (1995) · Journal of Virology · doi:10.1128/jvi.69.11.6687-6696.1995 · Cited by 154
Photo-Cross-Linking Studies Suggest a Model for the Architecture of an Active Human Immunodeficiency Virus Type 1 Integrase−DNA Complex
Heuer, T. S., & Brown, P. O. (1998) · Biochemistry · doi:10.1021/bi972949c · Cited by 148
Catalytic domain of human immunodeficiency virus type 1 integrase: identification of a soluble mutant by systematic replacement of hydrophobic residues.
Jenkins, T. M., Hickman, A. B., Dyda, F., Ghirlando, R., Davies, D. R., & Craigie, R. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.13.6057 · Cited by 143
Architectural elements in nucleoprotein complexes: interchangeability of specific and non‐specific DNA binding proteins.
Segall, A. M., Goodman, S. D., & Nash, H. A. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06775.x · Cited by 140
Marked infidelity of human immunodeficiency virus type 1 reverse transcriptase at RNA and DNA template ends.
Patel, P. H., & Preston, B. D. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.2.549 · Cited by 138
Retroviral DNA Integration—Mechanism and Consequences
Lewinski, M. K., & Bushman, F. D. (2005) · Advances in genetics · doi:10.1016/s0065-2660(05)55005-3 · Cited by 140
Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNa termini mediated by the viral integrase protein
Vink, C., Yeheskiely, E., van der MAREL, G. A., BOOM, J. H. V., & Plasterk, R. H. A. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.24.6691 · Cited by 129
The role of Gag in human immunodeficiency virus type 1 virion morphogenesis and early steps of the viral life cycle
Reicin, A. S., Öhagen, Å., Yin, L., Höglund, S., & Goff, S. P. (1996) · Journal of Virology · doi:10.1128/jvi.70.12.8645-8652.1996 · Cited by 125
Self-citation
Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae
Leavitt, A. D., Rose, R. B., & Varmus, H. E. (1992) · Journal of Virology · doi:10.1128/jvi.66.4.2359-2368.1992 · Cited by 126
Expression of the gag-pol fusion protein of Moloney murine leukemia virus without gag protein does not induce virion formation or proteolytic processing
Felsenstein, K. M., & Goff, S. P. (1988) · Journal of Virology · doi:10.1128/jvi.62.6.2179-2182.1988 · Cited by 124
Self-citation
Genetic analysis of the human immunodeficiency virus type 1 integrase protein
Shin, C., Taddeo, B., Haseltine, W. A., & Farnet, C. M. (1994) · Journal of Virology · doi:10.1128/jvi.68.3.1633-1642.1994 · Cited by 114
Methods for Gene Transfer to the Central Nervous System
Kantor, B., Bailey, R. M., Wimberly, K., Kalburgi, S. N., & Gray, S. J. (2014) · Advances in Genetics · doi:10.1016/b978-0-12-800149-3.00003-2 · Cited by 109
Integration of mini-retroviral DNA: a cell-free reaction for biochemical analysis of retroviral integration
Fujiwara, T., & Craigie, R. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.9.3065 · Cited by 109
Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein
Luban, J., & Goff, S. P. (1991) · Journal of Virology · doi:10.1128/jvi.65.6.3203-3212.1991 · Cited by 108
Self-citation
Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions
Sherman, P. A., Dickson, M. L., & Fyfe, J. A. (1992) · Journal of Virology · doi:10.1128/jvi.66.6.3593-3601.1992 · Cited by 107
Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer‐associated reverse transcriptase errors
Kulpa, D. A., Topping, R. S., & Telesnitsky, A. (1997) · The EMBO Journal · doi:10.1093/emboj/16.4.856 · Cited by 104
Molecular breeding of viruses
Soong, N.-W., Nomura, L. E., Pekrun, K., Reed, M., Sheppard, L., Dawes, G. N., & Stemmer, W. P. C. (2000) · Nature Genetics · doi:10.1038/78132 · Cited by 101
RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-template.
Telesnitsky, A., & Goff, S. P. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.4.1276 · Cited by 95
Self-citation
Retroviral Integrase Structure and DNA Recombination Mechanism
Engelman, A., & Cherepanov, P. (2014) · Microbiology Spectrum · doi:10.1128/microbiolspec.mdna3-0024-2014 · Cited by 101
gas7 : A gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation
Ju, Y., Chang, A. C. Y., She, B.-R., Tsaur, M.-L., Hwang, H.-M., Chao, C. C. ‐., Cohen, S. N., & Lin‐Chao, S. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.19.11423 · Cited by 89
Overlapping retrovirus U5 sequence elements are required for efficient integration and initiation of reverse transcription
Cobrinik, D. E., Aiyar, A. A., Ge, Z., Katzman, M., Huang, H., & Leis, J. P. (1991) · Journal of Virology · doi:10.1128/jvi.65.7.3864-3872.1991 · Cited by 89
Plus-strand priming by Moloney murine leukemia virus
Rattray, A. J., & Champoux, J. J. (1989) · Journal of Molecular Biology · doi:10.1016/0022-2836(89)90508-1 · Cited by 84
A transposon with an unusual arrangement of long terminal repeats in the green alga Chlamydomonas reinhardtii.
Day, A., Schirmer-Rahire, M., Kuchka, M. R., Mayfield, S. P., & Rochaix, J. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb03029.x · Cited by 78
Construction and analysis of deletion mutations in the U5 region of Moloney murine leukemia virus: effects on RNA packaging and reverse transcription
Murphy, J. E., & Goff, S. P. (1989) · Journal of Virology · doi:10.1128/jvi.63.1.319-327.1989 · Cited by 82
Self-citation
Replicative retroviral vectors for cancer gene therapy
Solly, S. K., Trajcevski, S., Frisén, C., Holzer, G. W., Nelson, E., Clerc, B., Abordo‐Adesida, E., Castro, M. G., Lowenstein, P. R., & Klatzmann, D. (2002) · Cancer Gene Therapy · doi:10.1038/sj.cgt.7700521 · Cited by 80
Sequence requirements for integration of Moloney murine leukemia virus DNA in vitro
Bushman, F. D., & Craigie, R. (1990) · Journal of Virology · doi:10.1128/jvi.64.11.5645-5648.1990 · Cited by 81
Sequence of the circle junction of human immunodeficiency virus type 1: implications for reverse transcription and integration
Whitcomb, J. M., Kumar, R. V., & Hughes, S. H. (1990) · Journal of Virology · doi:10.1128/jvi.64.10.4903-4906.1990 · Cited by 80
Abortive reverse transcription by mutants of Moloney murine leukemia virus deficient in the reverse transcriptase-associated RNase H function
Tanese, N., Telesnitsky, A., & Goff, S. P. (1991) · Journal of Virology · doi:10.1128/jvi.65.8.4387-4397.1991 · Cited by 78
Self-citation
Incorporation of homologous and heterologous proteins into the envelope of Moloney murine leukemia virus
Suomalainen, M., & Garoff, H. (1994) · Journal of Virology · doi:10.1128/jvi.68.8.4879-4889.1994 · Cited by 77
The N-terminal region of HIV-1 integrase is required for integration activity, but not for DNA-binding
Schauer, M., & Billich, A. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(92)91708-x · Cited by 77
Specificity of Rous sarcoma virus nucleocapsid protein in genomic RNA packaging
Dupraz, P., & Spahr, P. (1992) · Journal of Virology · doi:10.1128/jvi.66.8.4662-4670.1992 · Cited by 77
Evidence for a Stem Cell-Specific Repressor of Moloney Murine Leukemia Virus Expression in Embryonal Carcinoma Cells
Loh, T., Sievert, L. L., & Scott, R. W. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.8.4045 · Cited by 75
Disruption of the terminal base pairs of retroviral DNA during integration.Preprint
Scottoline, B. P., Chow, S. A., Ellison, V., & Brown, P. O. (1997) · Genes & Development · doi:10.1101/gad.11.3.371 · Cited by 75
Clinical Applications Involving CNS Gene Transfer
Kantor, B., McCown, T., Leone, P., & Gray, S. J. (2014) · Advances in Genetics · doi:10.1016/b978-0-12-800149-3.00002-0 · Cited by 74
Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA
Vink, C., Lutzke, R. A. P., & Plasterk, R. H. A. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.20.4103 · Cited by 73
Specificity of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H in removal of the minus-strand primer, tRNA(Lys3).
Smith, J. S., & Roth, M. J. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42147-3 · Cited by 73
A specific terminal structure is required for Ty1 transposition.Preprint
Eichinger, D. J., & Boeke, J. D. (1990) · Genes & Development · doi:10.1101/gad.4.3.324 · Cited by 73
Incomplete removal of the RNA primer for minus-strand DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase
Pullen, K., Ishimoto, L. K., & Champoux, J. J. (1992) · Journal of Virology · doi:10.1128/jvi.66.1.367-373.1992 · Cited by 72
The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates
Wolfe, A. L., Felock, P. J., Hastings, J. C., Blau, C., & Hazuda, D. J. (1996) · Journal of Virology · doi:10.1128/jvi.70.3.1424-1432.1996 · Cited by 67
The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase.
Pullen, K., Rattray, A. J., & Champoux, J. J. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53242-7 · Cited by 66
Identification of a high affinity nucleocapsid protein binding element within the moloney murine leukemia virus Ψ-RNA packaging signal: implications for genome recognition
D’Souza, V. M., Melamed, J., Habib, D., Pullen, K. E., Wallace, K., & Summers, M. F. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.5139 · Cited by 66
Mutational analysis of the envelope gene of Moloney murine leukemia virus
Gray, K. D., & Roth, M. J. (1993) · Journal of Virology · doi:10.1128/jvi.67.6.3489-3496.1993 · Cited by 66
Genetic assay for multimerization of retroviral gag polyproteins
Luban, J., Ålin, K., Bossolt, K. L., Humaran, T. J., & Goff, S. P. (1992) · Journal of Virology · doi:10.1128/jvi.66.8.5157-5160.1992 · Cited by 66
Self-citation
Human Endogenous Retrovirus K Gag Coassembles with HIV-1 Gag and Reduces the Release Efficiency and Infectivity of HIV-1
Monde, K., Contreras-Galindo, R., Kaplan, M. H., Markovitz, D. M., & Ono, A. (2012) · Journal of Virology · doi:10.1128/jvi.00301-12 · Cited by 65
Synthesis, biological evaluation, and molecular modeling studies of new 1,3,4-oxadiazole- and 1,3,4-thiadiazole-substituted 4-oxo-4H-pyrido[1,2-a]pyrimidines as anti-HIV-1 agents
Hajimahdi, Z., Zarghi, A., Zabihollahi, R., & Aghasadeghi, M. R. (2012) · Medicinal Chemistry Research · doi:10.1007/s00044-012-0241-5 · Cited by 64
Genetic analysis of homomeric interactions of human immunodeficiency virus type 1 integrase using the yeast two-hybrid system.
Kalpana, G. V., & Goff, S. P. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.22.10593 · Cited by 63
Self-citation
In vivo selection of protease cleavage sites from retrovirus display libraries
Buchholz, C. J., Peng, K.-W., Morling, F. J., Zhang, J., Cosset, F., & Russell, S. J. (1998) · Nature Biotechnology · doi:10.1038/nbt1098-951 · Cited by 63
Murine Leukemia Viruses: Objects and Organisms
Rein, A. R. (2011) · Advances in Virology · doi:10.1155/2011/403419 · Cited by 69
Two defective forms of reverse transcriptase can complement to restore retroviral infectivity.
Telesnitsky, A., & Goff, S. P. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06128.x · Cited by 61
Self-citation
Altering the Intracellular Environment Increases the Frequency of Tandem Repeat Deletion during Moloney Murine Leukemia Virus Reverse Transcription
Pfeiffer, J. K., Topping, R. S., Shin, N.-H., & Telesnitsky, A. (1999) · Journal of Virology · doi:10.1128/jvi.73.10.8441-8447.1999 · Cited by 62
Reverse Transcriptase of Moloney Murine Leukemia Virus Binds to Eukaryotic Release Factor 1 to Modulate Suppression of Translational Termination
Orlova, M., Yueh, A., Leung, J., & Goff, S. P. (2003) · Cell · doi:10.1016/s0092-8674(03)00805-5 · Cited by 59
Self-citation
Characterization of the forward and reverse integration reactions of the Moloney murine leukemia virus integrase protein purified from Escherichia coli.
Jonsson, C. B., Donzella, G. A., & Roth, M. J. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54098-9 · Cited by 59
Retroviral Display of Antibody Fragments; Interdomain Spacing Strongly Influences Vector Infectivity
Ager, S., Nilson, B., Morling, F. J., Peng, K.-W., Cosset, F., & Russell, S. J. (1996) · Human Gene Therapy · doi:10.1089/hum.1996.7.17-2157 · Cited by 58
Removal of 3'-OH-terminal nucleotides from blunt-ended long terminal repeat termini by the avian retrovirus integration protein
Vora, A. C., Fitzgerald, M. L., & Grandgenett, D. P. (1990) · Journal of Virology · doi:10.1128/jvi.64.11.5656-5659.1990 · Cited by 58
MLV glycosylated-Gag is an infectivity factor that rescues Nef-deficient HIV-1
Pizzato, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001554107 · Cited by 56
Interaction of Moloney murine leukemia virus matrix protein with IQGAP
Leung, J., Yueh, A., Appah, F. S. K., Yuan, B., Santos, K. D. L., & Goff, S. P. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601097 · Cited by 56
Self-citation
Defects in Moloney murine leukemia virus replication caused by a reverse transcriptase mutation modeled on the structure of Escherichia coli RNase H
Telesnitsky, A., Blain, S. W., & Goff, S. P. (1992) · Journal of Virology · doi:10.1128/jvi.66.2.615-622.1992 · Cited by 55
Self-citation
Molecular mechanism of retroviral DNA integration
Kulkosky, J., & Skalka, A. M. (1994) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(94)90062-0 · Cited by 56
Footprints on the viral DNA ends in Moloney murine leukemia virus preintegration complexes reflect a specific association with integrase
Wei, S.-Q., Mizuuchi, K., & Craigie, R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.18.10535 · Cited by 56
Membrane Binding and Subcellular Localization of Retroviral Gag Proteins Are Differentially Regulated by MA Interactions with Phosphatidylinositol-(4,5)-Bisphosphate and RNA
Inlora, J., Collins, D. R., Trubin, M. E., Chung, J. Y. J., & Ono, A. (2014) · mBio · doi:10.1128/mbio.02202-14 · Cited by 61
Interaction of Moloney Murine Leukemia Virus Capsid with Ubc9 and PIASy Mediates SUMO-1 Addition Required Early in Infection
Yueh, A., Leung, J., Bhattacharyya, S., Perrone, L. A., Santos, K. D. L., Pu, S., & Goff, S. P. (2005) · Journal of Virology · doi:10.1128/jvi.80.1.342-352.2006 · Cited by 55
Self-citation
Effects of Varying Sequence Similarity on the Frequency of Repeat Deletion during Reverse Transcription of a Human Immunodeficiency Virus Type 1 Vector
An, W., & Telesnitsky, A. (2002) · Journal of Virology · doi:10.1128/jvi.76.15.7897-7902.2002 · Cited by 54
An RNA Structural Switch Regulates Diploid Genome Packaging by Moloney Murine Leukemia Virus
Miyazaki, Y., Garcia, E. L., King, S. R., Iyalla, K., Loeliger, K. B., Starck, P., Syed, S., Telesnitsky, A., & Summers, M. F. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.11.033 · Cited by 55
The Carboxy-Terminal Fragment of Nucleolin Interacts with the Nucleocapsid Domain of Retroviral Gag Proteins and Inhibits Virion Assembly
Bacharach, E., Gonsky, J., Ålin, K., Orlova, M., & Goff, S. (2000) · Journal of Virology · doi:10.1128/jvi.74.23.11027-11039.2000 · Cited by 50
Self-citation
Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites.
Bushman, F. D., & Craigie, R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.8.3458 · Cited by 51
Plus-strand origin for human immunodeficiency virus type 1: implications for integration
Pullen, K., & Champoux, J. J. (1990) · Journal of Virology · doi:10.1128/jvi.64.12.6274-6277.1990 · Cited by 50
Production of infectious recombinant Moloney murine leukemia virus particles in BHK cells using Semliki Forest virus-derived RNA expression vectors.
Li, K. J., & Garoff, H. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11658 · Cited by 50
Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production
Wang, M. Q., Kim, W., Gao, G., Torrey, T. A., Morse, H. C., Camilli, P. V. D., & Goff, S. P. (2003) · Journal of Biology · doi:10.1186/1475-4924-3-4 · Cited by 49
Self-citation
Role of the His-Cys finger of Moloney murine leukemia virus integrase protein in integration and disintegration
Jonsson, C. B., & Roth, M. J. (1993) · Journal of Virology · doi:10.1128/jvi.67.9.5562-5571.1993 · Cited by 48
Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors via transactivation of proviral LTR
Boyd, K. E., Xiao, Y.-Y., Fan, K., Poholek, A. C., Copeland, N. G., Jenkins, N. A., & Perkins, A. S. (2005) · Blood · doi:10.1182/blood-2003-05-1626 · Cited by 47
Nonrandom Dimerization of Murine Leukemia Virus Genomic RNAs
Flynn, J. A., An, W., King, S. R., & Telesnitsky, A. (2004) · Journal of Virology · doi:10.1128/jvi.78.22.12129-12139.2004 · Cited by 47
Analysis of long terminal repeat circle junctions of human immunodeficiency virus type 1
Smith, J. S., Kim, S. Y., & Roth, M. J. (1990) · Journal of Virology · doi:10.1128/jvi.64.12.6286-6290.1990 · Cited by 47
Retroviral pseudotypes produced by rescue of a moloney murine leukemia virus vector by C-type, but not D-type, retroviruses
Takeuchi, Y., Simpson, G. R., Vile, R. G., Weiss, R. A., & Collins, M. K. (1992) · Virology · doi:10.1016/0042-6822(92)90049-u · Cited by 46
Phosphorylated Serine Residues and an Arginine-Rich Domain of the Moloney Murine Leukemia Virus p12 Protein Are Required for Early Events of Viral Infection
Yueh, A., & Goff, S. (2003) · Journal of Virology · doi:10.1128/jvi.77.3.1820-1829.2003 · Cited by 49
Self-citation
Effects on DNA synthesis and translocation caused by mutations in the RNase H domain of Moloney murine leukemia virus reverse transcriptase
Blain, S. W., & Goff, S. P. (1995) · Journal of Virology · doi:10.1128/jvi.69.7.4440-4452.1995 · Cited by 44
Self-citation
The Gag Cleavage Product, p12, is a Functional Constituent of the Murine Leukemia Virus Pre-Integration Complex
Prizan-Ravid, A., Elis, E., Laham-Karam, N., Selig, S., Ehrlich, M., & Bacharach, E. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001183 · Cited by 43
Replication of Lengthened Moloney Murine Leukemia Virus Genomes Is Impaired at Multiple Stages
Shin, N.-H., Hartigan-O’Connor, D. J., Pfeiffer, J. K., & Telesnitsky, A. (2000) · Journal of Virology · doi:10.1128/jvi.74.6.2694-2702.2000 · Cited by 43
Effects of Limiting Homology at the Site of Intermolecular Recombinogenic Template Switching during Moloney Murine Leukemia Virus Replication
Pfeiffer, J. K., & Telesnitsky, A. (2001) · Journal of Virology · doi:10.1128/jvi.75.23.11263-11274.2001 · Cited by 46
Substrate Recognition by Retroviral Integrases
Katzman, M., & Katz, R. A. (1999) · Advances in virus research · doi:10.1016/s0065-3527(08)60307-3 · Cited by 43
Retroviral integration: in vitro host site selection by avian integrase
Fitzgerald, M. L., & Grandgenett, D. P. (1994) · Journal of Virology · doi:10.1128/jvi.68.7.4314-4321.1994 · Cited by 42

Authors: Colicelli, J., & Goff, S. P.
Affiliations: Columbia University (US)
ORCID: Goff, Stephen P.
Venue: Journal of Molecular Biology
Publisher: Elsevier BV
Published: 1988-01
Volume: 199
Issue: 1
Pages: 47-59
ISSN: 0022-2836 (ISSN-L)
DOI: 10.1016/0022-2836(88)90378-6
OpenAlex: W2041126567
Cited by: 198
References: 51
Citations by year: 2025: 2 · 2022: 2 · 2021: 1 · 2018: 3 · 2017: 2 · 2015: 2 · 2014: 8 · 2013: 2 · 2012: 7
FWCI: 5.37
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor, 6509 d)
Locations: Journal of Molecular Biology (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Funders: National Cancer Institute (CA 30488)
Topics: Life Sciences › Immunology and Microbiology › Immunology › T-cell and Retrovirus Studies
Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Virus-based gene therapy research
Keywords: retroviral integration, Moloney murine leukemia virus, inverted repeats, integration sites, insertion mutation, recombination, pseudorevertants, viral DNA
MeSH terms: Base Sequence, DNA, Circular, DNA, Viral, Genes, Viral, Molecular Sequence Data, Mutation, Phenotype, Recombination, Genetic, Retroviridae, Virus Replication

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Sequence and spacing requirements of a retrovirus integration site

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks