Substrate specificity of adrenocortical cytochrome P-450scc–I. Effect of structural modification of cholesterol side-chain on pregnenolone production

Isolation from adrenal cortex of a nonheme iron protein and a flavoprotein functional as a reduced triphosphopyridine nucleotide-cytochrome P-450 reductase

Omura, T., Sanders, E., Estabrook, R. W., Cooper, D. Y., & Rosenthal, O. (1966) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(66)90108-1 · Cited by 380 · see citing works

Vitamin D. Basic Research and its Clinical Application

Norman, A. W., Schaefer, K., Herrath, D. V., et al. (1979) · De Gruyter eBooks · doi:10.1515/9783112330029 · Cited by 318 · see citing works

Cytochrome P-450 from Bovine Adrenocortical Mitochondria: an Enzyme for the Side Chain Cleavage of Cholesterol

Shikita, M., & Hall, P. F. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)43546-1 · Cited by 154 · see citing works

Improved purification of bovine adrenal iron-sulfur protein

Suhara, K., Takemori, S., & Katagiri, M. (1972) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(72)90079-7 · Cited by 148 · see citing works

The purification and properties of NADPH‐adrenodoxin reductase from bovine adrenocortical mitochondria

Suhara, K., Ikeda, Y., Takemori, S., & Katagiri, M. (1972) · FEBS Letters · doi:10.1016/0014-5793(72)80673-2 · Cited by 89 · see citing works

Oxidation of cholesterol and cholesterol analogues by mitochondrial preparations of steroid-hormone-producing tissue

Arthur, J. R., Blair, H. A. F., Boyd, G. S., Mason, J. I., & Suckling, K. E. (1976) · Biochemical Journal · doi:10.1042/bj1580047 · Cited by 56 · see citing works

Synthesis of the fungal sex hormone antheridiol

Edwards, J. A., MILLS, J. S., Sundeen, J. E., et al. (1969) · Journal of the American Chemical Society · doi:10.1021/ja01033a055 · Cited by 51 · see citing works

Synthesis of Active Forms of Vitamin D. I. A Facile Synthesis of 25-Hydroxycholesterol

Morisaki, M., Rubio-Lightbourn, J., & IKEKAWA, N. (1973) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.21.457 · Cited by 41 · see citing works

17alpha;-Hydroxy-25-fluorovitamin D3: a potent analog of 1α,25-dihydroxyvitamin D3

Napoli, J. L., Fivizzani, M. A., Schnoes, H. K., et al. (1978) · Biochemistry · doi:10.1021/bi00605a021 · Cited by 39 · see citing works

Stereochemical specificity at carbon‐20 and ‐22 of hydroxylated cholesterols for side‐chain cleavage by adrenocortical cytochrome P‐450scc

Morisaki, M., Satô, S., & Ikekawa, N. (1976) · FEBS Letters · doi:10.1016/0014-5793(76)80999-4 · Cited by 38 · see citing works

Pregnenolone formation from cholesterol in bovine adrenal cortex mitochondria: Proposal of a new mechanism

Kraaipoel, R. J., DEGENHART, H. J., Leferink, J. G., Beek, V. V., Leeuw-Boon, H. D., & VISSER, H. K. A. (1975) · FEBS Letters · doi:10.1016/0014-5793(75)80489-3 · Cited by 30 · see citing works

The conversion of 23,24-dinor-chol-5-en-3β-ol into steroid hormones

Tait, A. D. (1972) · Biochemical Journal · doi:10.1042/bj1280467 · Cited by 27 · see citing works

Studies on steroids. XLV. Synthesis of the four stereoisomers of 20,22-dihydroxycholesterol.

Morisaki, M., Satô, S., & Ikekawa, N. (1977) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.25.2576 · Cited by 27 · see citing works

Steroids. VI. Reaction of 24,28-epoxides of sterol side chain with boron trifluoride etherate

Ohtaka, H., Morisaki, M., & Ikekawa, N. (1973) · The Journal of Organic Chemistry · doi:10.1021/jo00949a015 · Cited by 26 · see citing works

Studies on steroids. LXIII. Synthesis of cholesterol analogs with a modified side chain.

Morisaki, M., SHIBATA, M., Duque, C., et al. (1980) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.28.606 · Cited by 24 · see citing works

Studies on the Plant Sterols and Triterpenes. II. Separation of Stigmasterol, β-Sitosterol and Campesterol, and about So-called "γ-Sitosterol."

Nishioka, I., Ikekawa, N., Yagi, A., et al. (1965) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.13.379 · Cited by 23 · see citing works

Biosynthesis of Pregnenolone from Cholesterol by Mitochondrial Enzymes of Bovine Adrenal Cortex. The Question of the Participation of the 20(22)-Olefins and 20,22-Epoxides of Cholesterol

Teicher, B. A., Koizumi, N., Koreeda, M., et al. (1978) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1978.tb20931.x · Cited by 23 · see citing works

Photolysis of cis,cis-1,3-cyclooctadiene

Nebe, W. J., & Fonken, G. J. (1969) · Journal of the American Chemical Society · doi:10.1021/ja01033a056 · Cited by 21 · see citing works

Synthesis of Active Forms of Vitamin D. V. A Practical Route to 1α, 25-Dihydroxycholesterol

森崎, 益., Julieta, R.-L., 池川, 信., et al. (1973) · Chemical and Pharmaceutical Bulletin · Cited by 18 · see citing works

Enzymatic side chain cleavage of C-20 alkyl and aryl analogs of (20-S)-20-hydroxycholesterol. Implications for the biosynthesis of pregnenolone

Hoyte, R. M., & Hochberg, R. B. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30218-1 · Cited by 16 · see citing works

Exclusion of 20(22)-dehydrocholesterol as an intermediate in the biosynthesis of pregnenolone in bovine adrenocortical mitochondrial acetone-dried powder preparations

Burstein, S., Byon, C. Y., Kimball, H. L., et al. (1976) · Steroids · doi:10.1016/s0039-128x(76)90224-5 · Cited by 16 · see citing works

Synthesis of Active Forms of Vitamin D. IV. Synthesis of 24, 25- and 25, 26-Dihydroxycholesterols

Seki, M., Morisaki, M., Ikekawa, N., et al. (1973) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.21.2783 · Cited by 16 · see citing works

Cholesterol 20,22-epoxides: No conversion to pregnenolone by adrenal cytochrome P-450scc

Morisaki, M., BANNAI, K., Ikekawa, N., & Shikita, M. (1976) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(76)90547-7 · Cited by 16 · see citing works

Studies on steroids. LI. Stereoselective introduction of 22- and 24-hydroxyl function in the steroidal side chain.

Ishiguro, M., Saito, H., Sakamoto, A., et al. (1978) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.26.3715 · Cited by 15 · see citing works

Formation of 4-methyl-3-pentenoic acid from cholesta-5, 24-dien-3β-ol by adrenal enzyme

Shimizu, K., & Gut, M. (1965) · Steroids · doi:10.1016/0039-128x(65)90005-x · Cited by 11 · see citing works

Biosynthesis of Pregnane Derivatives

Burstein, S., & Gut, M. (1971) · Advances in lipid research · doi:10.1016/b978-0-12-024909-1.50013-2 · Cited by 7 · see citing works

Biosynthesis and transformation of 20α 21-dihydroxycholesterol by rat adrenal preparations

Kaufmann, S. H. E., Sinterhauf, K., Diedrichsen, G., et al. (1979) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(79)90517-x · Cited by 6 · see citing works

Specificity of the cholesterol side-chain cleavage enzyme system of adrenal cortex

Burstein, S., Nickolson, R. C., Byon, C. Y., Kimball, H. L., & Gut, M. (1977) · Steroids · doi:10.1016/0039-128x(77)90092-7 · Cited by 2 · see citing works

Identification of a C26-sterol in urine and serum of patient with congenital adrenal hyperplasia.

Ikekawa, N., Fujimoto, Y., Ishiguro, M., et al. (1979) · Proceedings of the Japan Academy Series B · doi:10.2183/pjab.55.252 · Cited by 1 · see citing works

Molecular biology of steroid hormone synthesis

MILLER, W. L. (1988) · Endocrine Reviews · doi:10.1210/edrv-9-3-295 · Cited by 1,397 · see citing works

Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system

Strushkevich, N., MacKenzie, F., Cherkesova, T., Grabovec, I., Usanov, S., & Park, H.-W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019441108 · Cited by 337 · see citing works

Novel activities of CYP11A1 and their potential physiological significance

Slominski, A. T., Li, W., Kim, T.-K., Semak, I., Wang, J., Zjawiony, J. K., & Tuckey, R. C. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.11.010 · Cited by 292 · see citing works

Heterozygous mutation in the cholesterol side chain cleavage enzyme (P450scc) gene in a patient with 46,XY sex reversal and adrenal insufficiency

Tajima, T., Fujieda, K., Kouda, N., Nakae, J., & Miller, W. L. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.8.7748 · Cited by 196 · see citing works

Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1

Mast, N., Annalora, A. J., Lodowski, D. T., Palczewski, K., Stout, C. D., & Pikuleva, I. A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.188433 · Cited by 138 · see citing works

Side‐chain specificities of human and bovine cytochromes <i>P</i>‐450_scc

TUCKEY, R. C., & CAMERON, K. J. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb18235.x · Cited by 38 · see citing works

Heterodox notions on pathways of steroidogenesis

LIEBERMAN, S., & PRASAD, V. V. K. (1990) · Endocrine Reviews · doi:10.1210/edrv-11-4-469 · Cited by 35 · see citing works

The influence of the side chain on sterol side-chain cleavage in rat adrenal glands

Craig, I. F., Mason, J. I., Suckling, K. E., & Boyd, G. S. (1982) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(82)90017-0 · Cited by 7 · see citing works

In vitro studies of the adrenal metabolism of halogenated side-chain analogues of cholesterol

Mason, J. I., Arunachalam, T., & Caspi, E. (1983) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(83)90122-4 · Cited by 3 · see citing works

2β- and 16β-hydroxylase activity of CYP11A1 and direct stimulatory effect of estrogens on pregnenolone formation

Mosa, A., Neunzig, J., Gerber, A., Zapp, J., Hannemann, F., Pilak, P., & Bernhardt, R. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.02.014 · Cited by 25 · see citing works

Ontogenesis of cholesterol side-chain cleavage activity in the ovine adrenal during late gestation

Naaman, E., Cathiard, A. M., & Durand, P. (1992) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(92)90165-f · Cited by 3 · see citing works

Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc

Kim, C. J., Lin, L., Huang, N., Quigley, C. A., AvRuskin, T. W., Achermann, J. C., & Miller, W. L. (2008) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2007-2330 · Cited by 139 · see citing works

Overview of Dehydroepiandrosterone Biosynthesis

Auchus, R. J. (2004) · Seminars in Reproductive Medicine · doi:10.1055/s-2004-861545 · Cited by 87 · see citing works

Does the endometrium synthesize progesterone?

Gentry, A. L., Evans-Hoeker, E. A., Lessey, B. A., Yuan, L., & Young, S. L. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2014.07.1011