Information processing in microtubules

Long-range coherence and energy storage in biological systems.

Fröhlich, H. (1968) · International Journal of Quantum Chemistry · doi:10.1002/qua.560020505 · Cited by 1,069

THE MECHANISM OF ACTION OF COLCHICINE

Borisy, G. G., & Taylor, E. W. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.34.2.525 · Cited by 1,058

Calmodulin—an intracellular calcium receptor

Means, A. R., & Dedman, J. R. (1980) · Nature · doi:10.1038/285073a0 · Cited by 967

Quenching of protein fluorescence by oxygen. Detection of structural fluctuations in proteins on the nanosecond time scale

Lakowicz, J. R., & Weber, G. (1973) · Biochemistry · doi:10.1021/bi00745a021 · Cited by 804

Tissue interactions with nonionizing electromagnetic fields.

ADEY, W. R. (1981) · Physiological Reviews · doi:10.1152/physrev.1981.61.2.435 · Cited by 660

SYNAPSES IN THE CENTRAL NERVOUS SYSTEM

Palay, S. L. (1956) · The Journal of Cell Biology · doi:10.1083/jcb.2.4.193 · Cited by 634

Arrangement of subunits in flagellar microtubules

Amos, L. A., & Klug, A. (1974) · Journal of Cell Science · doi:10.1242/jcs.14.3.523 · Cited by 514

Evidence for four classes of microtubules in individual cells

Behnke, O., & Forer, A. (1967) · Journal of Cell Science · doi:10.1242/jcs.2.2.169 · Cited by 418

Properties of colchicine binding protein from chick embryo brain. Interactions with vinca alkaloids and podophyllotoxin

Wilson, L. (1970) · Biochemistry · doi:10.1021/bi00827a026 · Cited by 387

In vitro reconstitution of calf brain microtubules: effects of solution variables

Lee, J. C., & Timasheff, S. N. (1977) · Biochemistry · doi:10.1021/bi00627a037 · Cited by 335

Long Range Coherence and the Action of Enzymes

Fröhlich, H. (1970) · Nature · doi:10.1038/2281093a0 · Cited by 308

Opioid Receptors Undergo Axonal Flow

Young, W. S., Wamsley, J. K., Zarbin, M. A., & Kuhar, M. J. (1980) · Science · doi:10.1126/science.6158097 · Cited by 268

Definition of three classes of binding sites in isolated microtubule crystals

Bryan, J. (1972) · Biochemistry · doi:10.1021/bi00764a010 · Cited by 246

Introduction to a submolecular biology

Szent‐Györgyi, A. (1960) · Medical Entomology and Zoology · Cited by 231

NEUROTROPHIC CONTROL OF LIMB REGENERATION IN THE NEWT*

Singer, M. (1974) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1974.tb20520.x · Cited by 222

MORPHOLOGICAL CORRELATES OF INCREASED COUPLING RESISTANCE AT AN ELECTROTONIC SYNAPSE

Pappas, G. D., Asada, Y., & Bennett, M. V. L. (1971) · The Journal of Cell Biology · doi:10.1083/jcb.49.1.173 · Cited by 196

Organic semiconductors

Pethig, R. (1968) · Electronics and Power · doi:10.1049/ep.1968.0243 · Cited by 194

The Ground Substance of the Living Cell

Porter, K. R., & Tucker, J. Β. (1981) · Scientific American · doi:10.1038/scientificamerican0381-56 · Cited by 144

Characteristics of the fast transport system in mammalian nerve fibers

Ochs, S., & Ranish, N. A. (1969) · Journal of Neurobiology · doi:10.1002/neu.480010211 · Cited by 127

Removal of the projections from cytoplasmic microtubules in vitro by digestion with trypsin.

Vallee, R. B., & Borisy, G. G. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32839-9 · Cited by 125

Introduction to a submolecular biology

Tinoco, I. (1961) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(61)90091-1 · Cited by 124

Cytoskeletal Elements in Neurons

Bray, D., & GILBERT, D. S. (1981) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.04.030181.002445 · Cited by 107

BRIDGES BETWEEN MICROTUBULES

McIntosh, J. R. (1974) · The Journal of Cell Biology · doi:10.1083/jcb.61.1.166 · Cited by 107

Structure of the tubulin dimer in zinc-induced sheets

Baker, T. S., & Amos, L. (1978) · Journal of Molecular Biology · doi:10.1016/0022-2836(78)90378-9 · Cited by 102

HOW MICROTUBULE PATTERNS ARE GENERATED

Tilney, L. G. (1971) · The Journal of Cell Biology · doi:10.1083/jcb.51.3.837 · Cited by 97

Microtubule theory of sensory transduction

Atema, J. (1973) · Journal of Theoretical Biology · doi:10.1016/0022-5193(73)90233-6 · Cited by 91

EFFECTS OF GENERAL ANÆSTHETICS ON MICROTUBULES

ALLISON, A. C., & Nunn, J. F. (1968) · The Lancet · doi:10.1016/s0140-6736(68)91821-7 · Cited by 88

Ciba Foundation Symposium ‐ Principles of Biomolecular Organization

(1966) · Novartis Foundation symposium · doi:10.1002/9780470719442 · Cited by 74

Improved Holographic Model of Temporal Recall

Габор, Д. (1968) · Nature · doi:10.1038/2171288a0 · Cited by 73

Non-coherent optical processing

Rogers, G. L. (1975) · Optics & Laser Technology · doi:10.1016/0030-3992(75)90053-5 · Cited by 66

Intermolecular Electron Transfer by Quantum Mechanical Tunneling

Miller, J. R. A. (1975) · Science · doi:10.1126/science.189.4198.221 · Cited by 65

Experimental methods in biophysical chemistry

Nicolau, C. (1973) · Cited by 62

Fluorescence techniques for following interactions of microtubule subunits and membranes

BECKER, J. S., Oliver, J. M., & Berlin, R. D. (1975) · Nature · doi:10.1038/254152a0 · Cited by 60

Microtubules and axoplasmic transport

Paulson, J. C., & McClure, W. O. (1974) · Brain Research · doi:10.1016/0006-8993(74)91053-1 · Cited by 56

The Possible Involvement of Brain Microtubules in Memory Fixation

Cronly-Dillon, J. R., Carden, D. E., & Birks, C. (1974) · Journal of Experimental Biology · doi:10.1242/jeb.61.2.443 · Cited by 56

The Role of Optics in Applying Correlation Functions to Pattern Recognition

McLachlan, D. (1962) · Journal of the Optical Society of America · doi:10.1364/josa.52.000454 · Cited by 49

EFFECTS OF LIDOCAINE ON RABBIT BRAIN MICROTUBULAR PROTEIN1

Haschke, R. H., Byers, M. R., & Fink, B. R. (1974) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1974.tb04302.x · Cited by 49

The possibilities of neural holographic processes within the brain

Westlake, P. R. (1970) · Kybernetik · doi:10.1007/bf00571694 · Cited by 48

In vivo incorporation of [14C]tyrosine into the C-terminal position of the α subunit of tubulin

Argaraña, C. E., Arce, C. A., Barra, H. S., & Caputto, R. (1977) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(77)90037-6 · Cited by 48

Models of membranes of cerebral cells as substrates for information storage

ADEY, W. R. (1977) · Biosystems · doi:10.1016/0303-2647(77)90035-1 · Cited by 46

Optical Autocorrelation Measurement of Two-Dimensional Random Patterns

Kovásznay, L. S. G., & Arman, A. (1957) · Review of Scientific Instruments · doi:10.1063/1.1715725 · Cited by 46

Thyroid tubulin, purification and properties

Bhattacharyya, B., & Wolff, J. (1974) · Biochemistry · doi:10.1021/bi00708a020 · Cited by 40

Effect of electrical stimulation on nuclear microfilaments and microtubules of sympathetic neurons submitted to cycloheximide

̈te, R. S., Mei, N., & Vuillet-Luciani, J. (1973) · Brain Research · doi:10.1016/0006-8993(73)90744-0 · Cited by 38

Shape and pattern specification during microtubule bundle assembly

Tucker, J. B. (1977) · Nature · doi:10.1038/266022a0 · Cited by 37

Solitons in a Reaction-Diffusion System

Tuckwell, H. C. (1979) · Science · doi:10.1126/science.205.4405.493 · Cited by 36

Proteins associated with tubulin

Sandoval, I. V., & Cuatrecasas, P. (1976) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(76)90025-5 · Cited by 34

PHASE TRANSITIONS IN BIOLOGICAL SYSTEMS: MANIFESTATIONS OF COOPERATIVE PROCESSES IN VICINAL WATER*

Drost‐Hansen, W. (1973) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1973.tb30773.x · Cited by 33

Neuronal membrane: a physical synthesis

Grodsky, I. T. (1976) · Mathematical Biosciences · doi:10.1016/0025-5564(76)90124-3 · Cited by 32

Tubulin synthesis in developing rat visual cortex

Cronly-Dillon, J. R., & Perry, G. (1976) · Nature · doi:10.1038/261581a0 · Cited by 29

Motility of the microtubular axostyle in Pyrsonympha.

Langford, G. M., & Inoué, S. (1979) · The Journal of Cell Biology · doi:10.1083/jcb.80.3.521 · Cited by 26

Ch'i: A Neural Hologram? Microtubules, Bioholography, and Acupuncture

Hameroff, S. R. (1974) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x74000213 · Cited by 25

Interaction of Chlorpromazine with Brain Microtubule Subunit Protein

CANN, J. R., & Hinman, N. D. (1975) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10633-0 · Cited by 24

Axonal microtubules: Their regulation by the electrical activity of the nerve

Álvarez, J., & Ramírez, B. U. (1979) · Neuroscience Letters · doi:10.1016/0304-3940(79)91522-2 · Cited by 23

Tubulin synthesis during a critical period in visual cortex development

Perry, G., & Cronly-Dillon, J. R. (1978) · Brain Research · doi:10.1016/0006-8993(78)90646-7 · Cited by 23

Coherent Oscillations in Biological Systems II Limit Cycle Collapse and the Onset of Travelling Waves in Fröhlich's Brain Wave Model

Kaiser, F. (1978) · Zeitschrift für Naturforschung A · doi:10.1515/zna-1978-0404 · Cited by 22

Spatial organization of the microtubule-associated proteins of reassembled brain microtubules

Burns, R. G. (1978) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(78)90023-0 · Cited by 17

Hydantoin drugs inhibit polymerization of pure microtubular protein.

MACKINNEY, A. A., VYAS, R., & Walker, D. (1978) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)31125-0 · Cited by 15

Non-coherent Optical Processing

Hall, R. J. (1978) · Optica Acta International Journal of Optics · doi:10.1080/713819696 · Cited by 12

Effects of barbiturates on ultrastructure and polymerization of microtubules in vitro

Edstr�m, A., Ha, H., Larsson, H., & Wallin, M. (1975) · Cell and Tissue Research · doi:10.1007/bf00223260 · Cited by 12

MODELS FOR ENERGY TRANSDUCTION AND TRANSFER IN BIOLOGICAL SYSTEMS

Shohet, J. L., & Reible, S. (1974) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1974.tb14429.x · Cited by 10

Microtubules in non-medullated fibres: Effect of the action potential

Álvarez, J. (1979) · Neuroscience Letters · doi:10.1016/0304-3940(79)91521-0 · Cited by 9

Microtubular proteins in the occipital cortex of rats housed in enriched and in impoverished environments

Jørgensen, O. S., & Meier, E. (1979) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1979.tb11747.x · Cited by 8

Mode locking in quantum optics

Sargent, M. (1973) · Applied Physics A · doi:10.1007/bf00889543 · Cited by 6

SOLID STATE PHYSICAL MECHANISMS OF BIOLOGICAL ENERGY TRANSDUCTION*

Cope, F. W. (1974) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1974.tb14428.x · Cited by 6

A GENERAL PERSPECTIVE OF THE QUANTUM MECHANICAL FOUNDATIONS OF ENERGY TRANSDUCTION

Avery, J., & Pavlidou, C. M. E. (1974) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1974.tb14430.x · Cited by 5

MITOTIC ACCELERATION INDUCED IN GRASSHOPPER NEUROBLASTS BY SMALL DOSES OF MONOCHROMATIC ULTRAVIOLET RADIATION

Carlson, J. G., & Stephens, R. E. (1974) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1974.tb06540.x · Cited by 4

Die Perception endlicher linearer Ereignisfolgen

Bösel, R. (1970) · Kybernetik · doi:10.1007/bf00272660 · Cited by 3

Consciousness in the universe

Hameroff, S., & Penrose, R. (2014) · Physics of Life Reviews · doi:10.1016/j.plrev.2013.08.002 · Cited by 983

Importance of quantum decoherence in brain processes

Tegmark, M. (2000) · Physical Review E · doi:10.1103/physreve.61.4194 · Cited by 776

Orchestrated reduction of quantum coherence in brain microtubules: a model for consciousness

Hameroff, S., & Penrose, R. (1996) · Mathematics and Computers in Simulation · doi:10.1016/0378-4754(96)80476-9 · Cited by 641

Quantum computation in brain microtubules: decoherence and biological feasibility

Hagan, S., Hameroff, S. R., & Tuszyński, J. A. (2002) · Physical Review E · doi:10.1103/physreve.65.061901 · Cited by 389

On Having No Head: Cognition throughout Biological Systems

Baluška, F., & Levin, M. G. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00902 · Cited by 404

Information processing in brain microtubules

Faber, J., Portugal, R., & Rosa, L. P. (2005) · Biosystems · doi:10.1016/j.biosystems.2005.06.011 · Cited by 44

Models of information processing in microtubules

Hameroff, S. R., Watt, R. C., & Schneiker, C. W. (1987)

Dielectric polarization, electrical conduction, information processing and quantum computation in microtubules. Are they plausible?

Tuszyński, J. A., Brown, J. A., & Hawrylak, P. (1998) · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · doi:10.1098/rsta.1998.0255 · Cited by 85

Information processing mechanisms in microtubules at physiological temperature: Model predictions for experimental tests

Craddock, T. J. A., Beauchemin, C. A. A., & Tuszyński, J. A. (2009) · Biosystems · doi:10.1016/j.biosystems.2009.04.001 · Cited by 33

Role of microtubules in neurons: Context to information processing

Bhardwaj, R. (2023) · doi:10.13140/rg.2.2.20367.56485