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Cited by 104Thyroid Disorders and TreatmentsMaternal Mental Health During Pregnancy and PostpartumPregnancy and Medication Impact

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Maternal and perinatal outcome in thyrotoxicosis complicating pregnancy

Kriplani, A., Buckshee, K., Bhargava, V.L., Takkar, D., Ammini, A.C.·1994·European Journal of Obstetrics & Gynecology and Reproductive Biology
DOI 10.1016/0028-2243(94)90276-3
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Abstract

In this report we describe 32 pregnancies complicated by hyperthyroidism cared for over a 7-year period at AIIMS, New Delhi. In 6 cases hyperthyroidism was diagnosed during pregnancy; others were diagnosed before conception and were on antithyroid therapy during pregnancy. For control of thyrotoxicosis thiourea derivatives, carbimazole (CMZ) and propylthiouracil (PTU), were both used. The dosage of antithyroid drugs could be decreased or stopped in the third trimester in only 28% cases, while 50% cases did not require any change in the dosage during gestation and 21% required an increase in dosage with advancing gestation to control thyrotoxicosis. Maternal and fetal complications included preterm labour (25%), PIH (22%), thyroid crisis (9%) and intrauterine growth retardation (13%). Thyroid status of neonates was found abnormal in 9% cases, including 1 case (3%) of neonatal thyrotoxicosis with goitre and 2 (6%) cases of neonatal hypothyroidism. One maternal death occurred due to thyroid storm. No case of stillbirth or perinatal death occurred in the present study. In our experience of 32 cases maternal and fetal complications are reported with increased frequency, requiring close surveillance of thyroid status to maintain euthyroidism and intensive fetal monitoring during pregnancy to achieve good maternal and perinatal outcome.

Overview

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Crossref · 10.1016/0028-2243(94)90276-3

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17 of 17 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 1

  1. Thomas, 1987, Thyroid disease and reproductive dysfunction, Obstet Gynecol, 70, 789

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Metadata

Authors
Kriplani, A., Buckshee, K., Bhargava, V. L., Takkar, D., & Ammini, A. C.
Affiliations
All India Institute of Medical Sciences (IN)
ORCID
Venue
European Journal of Obstetrics & Gynecology and Reproductive Biology
Publisher
Elsevier BV
Published
1994-05
Volume
54
Issue
3
Pages
159-163
ISSN
  • 0028-2243 (ISSN-L)
  • 0301-2115
DOI
10.1016/0028-2243(94)90276-3
OpenAlex
W1969160789
Cited by
104
References
17
Citations by year
2025: 1 · 2024: 3 · 2023: 1 · 2021: 4 · 2020: 5 · 2019: 6 · 2018: 3 · 2017: 2 · 2016: 6 · 2015: 6 · 2014: 4 · 2013: 6 · 2012: 5
FWCI
0.29
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • European Journal of Obstetrics & Gynecology and Reproductive Biology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
Keywords
thyrotoxicosis, hyperthyroidism in pregnancy, antithyroid drugs, carbimazole, propylthiouracil, thiourea derivatives, thyroid storm, preterm labour, preeclampsia, fetal growth restriction, neonatal hypothyroidism, neonatal thyrotoxicosis, maternal mortality, fetal monitoring
MeSH terms
Adult, Female, Humans, Hyperthyroidism, Infant, Newborn, Obstetric Labor, Premature, Lactation, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Antithyroid Agents, Thyroid Function Tests, Thyrotoxicosis, Treatment Outcome

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