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On the role of organized multienzyme systems in cellular metabolism: A general synthesis

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Welch, G.Rickey·1978·Progress in Biophysics and Molecular Biology

DOI 10.1016/0079-6107(78)90019-6

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Dynamics of Enzyme Reactions and Metabolic Networks in Living Cells. A Physico-Chemical Approach
Ricard, J., Mulliert, G., Kellershohn, N., & Giudici‐Orticoni, M. (1994) · Progress in molecular and subcellular biology · doi:10.1007/978-3-642-78581-8_1 · Cited by 6
On the Field Structure of Metabolic Space-Time
Welch, G. R., & Smith, H. A. (1990) · Springer eBooks · doi:10.1007/978-94-009-1890-0_4 · Cited by 6
Self-citation
Reversible binding of glycolytic enzymes and size change in the actin-containing filaments of the frog skeletal muscle
Fulgenzi, G., Graciotti, L., Corsi, A., & Granata, A. L. (2001) · Journal of Muscle Research and Cell Motility · doi:10.1023/a:1014553718306 · Cited by 6
“It appears that cytoskeleton associations of enzymes contribute to metabolic regulation and compartmentation (Welch, 1977; Masters, 1984; Wang et al., 1997).”
Background
Diffusion theory in biology: its validity and relevance
Wheatley, D. N. (1993) · Journal of Biological Education · doi:10.1080/00219266.1993.9655331 · Cited by 6
A kinetic study on the diffusion-coupled reaction of a basic horseradish peroxidase adsorbed on the carboxymethylcellulose membrane.
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Metabolic dynamics in cells viewed as multilayered, distributed, mass‐energy‐information networks
Aon, M. A., & Cortassa, S. C. (2005) · Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics · doi:10.1002/047001153x.g308206 · Cited by 6
Study of chorismate mutase-prephenate dehydrogenase in crude cell extracts of Escherichia coli
Llewellyn, D. J., & Smith, G. D. (1979) · Biochemistry · doi:10.1021/bi00588a035 · Cited by 6
Modulation of enzyme catalysis in organized biological systems: a physico-chemical approach
Ricard, J. (1989) · Catalysis Today · doi:10.1016/0920-5861(89)80019-7 · Cited by 6
Cytosociological Aspects of Enzyme Action
Welch, G. R. (1986) · Springer eBooks · doi:10.1007/978-1-4684-5311-9_31 · Cited by 6
Self-citation
Data Analysis from Michaelis-Menten Kinetics: Ins and Outs
Keleti, T. (1981) · Springer eBooks · doi:10.1007/978-1-4613-3255-8_21 · Cited by 5
Concerning the mechanism for transfer of d-glucuronate from myo-inositol oxygenase to d-glucuronate reductase
Naber, N. I., & Hamilton, G. A. (1987) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/0167-4838(87)90078-1 · Cited by 5
Do centrioles contain ribosomes?
Kallenbach, R. J. (1983) · Bioscience Reports · doi:10.1007/bf01120209 · Cited by 5
Biophysics: whence it came, where it's going
Welch, G. R. (1988) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(88)90025-4 · Cited by 5
Self-citation
Of men, molecules, and (Ir)reducibility
Welch, G. R. (1989) · BioEssays · doi:10.1002/bies.950110608 · Cited by 5
Self-citation
The bacteriostatic mechanisms of sulfonamidotrimethoprim combinations
Toth-Martinez, B. L. (1977) · Biochemical Pharmacology · doi:10.1016/0006-2952(77)90315-x · Cited by 4
Interaction of Tetrahydropteroylpolyglutamates with Two Folate-Dependent Multifunctional Enzymes
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Maxwell’s Demons in Channelled Metabolism: Paradoxes and their Resolution
Westerhoff, H. V., & Kamp, F. (1986) · Springer eBooks · doi:10.1007/978-1-4684-5311-9_29 · Cited by 4
Die zeitliche Organisation des eukaryonten Energiestoffwechsels als Grundlage für die Signalverarbeitung im Photo‐und Thermoperiodismus
Wagner, E., & Fukshansky, L. (1985) · Berichte der Deutschen Botanischen Gesellschaft · doi:10.1111/j.1438-8677.1985.tb02901.x · Cited by 4
The cytosol, cytoplasm and cytomatrix
Masters, C. J. (1984) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(84)90071-9 · Cited by 4

Authors: Welch, G. R.
Affiliations: The University of Texas Health Science Center at Houston (US)
Corresponding author: Welch, G.Rickey
Venue: Progress in Biophysics and Molecular Biology
Publisher: Elsevier BV
Published: 1978
Volume: 32
Issue: 2
Pages: 103-191
ISSN: 0079-6107 (ISSN-L)
DOI: 10.1016/0079-6107(78)90019-6
OpenAlex: W2133890603
Cited by: 260
References: 277
Citations by year: 2025: 2 · 2024: 2 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 1 · 2017: 12 · 2016: 4 · 2015: 2 · 2014: 3 · 2012: 3
FWCI: 4.72
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 15716 d)
Locations: Progress in Biophysics and Molecular Biology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Molecular Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cancer and biochemical research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
Keywords: multienzyme systems, enzyme organization, cellular metabolism, enzyme kinetics, metabolic networks
MeSH terms: Catalysis, Cells, Diffusion, Escherichia coli, Euglena gracilis, Biological Evolution, Fatty Acids, Kinetics, Mathematics, Mitochondria, Models, Biological, Multienzyme Complexes, Neurospora crassa, Prephenate Dehydratase, Protein Conformation, Pyruvate Dehydrogenase Complex, Saccharomyces cerevisiae, Tetrahydrofolates, Tryptophan Synthase, Fatty Acid Synthases

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On the role of organized multienzyme systems in cellular metabolism: A general synthesis

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