The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Characterization of an efficient coronavirus ribosomal frameshifting signal: Requirement for an RNA pseudoknot
Open accessAbstract
The genomic RNA of the coronavirus IBV contains an efficient ribosomal frameshifting signal at the junction of two overlapping open reading frames. We have defined by deletion analysis an 86 nucleotide sequence encompassing the overlap region which is sufficient to allow frameshifting in a heterologous context. The upstream boundary of the signal consists of the sequence UUUAAAC, which is the likely site of ribosomal slippage. We show by creation of complementary nucleotide changes that the RNA downstream of this “slippery” sequence folds into a tertiary structure termed a pseudoknot, the formation of which is essential for efficient frameshifting.
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Cites
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
Birnboim, H. C., & Doly, J. (1979) · Nucleic Acids Research · doi:10.1093/nar/7.6.1513 · Cited by 14,686
Characterization of ribosomal frameshifting in HIV-1 gag-pol expression
Jacks, T., Power, M. D., Masiarz, F. R., Luciw, P. A., Barr, P. J., & Varmus, H. E. (1988) · Nature · doi:10.1038/331280a0 · Cited by 966
Moore, R., Dixon, M., Smith, R., Peters, G., & Dickson, C. (1987) · Journal of Virology · doi:10.1128/jvi.61.2.480-490.1987 · Cited by 256
Cited by
Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
Leppek, K., Das, R., & Barna, M. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.103 · Cited by 949
Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes
Kozak, M. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.21.8301 · Cited by 553
RNA pseudoknots: translational frameshifting and readthrough on viral RNAs
Ten Dam, E. B., Pleij, C. W. A., & Bosch, L. (1990) · Virus Genes · doi:10.1007/bf00678404 · Cited by 214
Brown, C. M., Stockwell, P. A., Trotman, C. N. A., & Tate, W. P. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.21.6339 · Cited by 191
A Comprehensive Review About SARS-CoV-2
Haque, S. M., Ashwaq, O., Sarief, A., & Azad John Mohamed, A. K. (2020) · Future Virology · doi:10.2217/fvl-2020-0124 · Cited by 121
Metadata
- Authors
- Brierley, I., Digard, P., & Inglis, S. C.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1989-05
- Volume
- 57
- Issue
- 4
- Pages
- 537-547
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2092974248
- Cited by
- 675
- References
- 3
- FWCI
- 13.14
- Type
- journal article
- Language
- en
- Open access
- green
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