The DOI matches its Crossref record; 43 of the 45 references it cites were found in a registry or an index.
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
Open accessAbstract
The mammalian olfactory system can recognize and discriminate a large number of different odorant molecules. The detection of chemically distinct odorants presumably results from the association of odorous ligands with specific receptors on olfactory sensory neurons. To address the problem of olfactory perception at a molecular level, we have cloned and characterized 18 different members of an extremely large multigene family that encodes seven transmembrane domain proteins whose expression is restricted to the olfactory epithelium. The members of this novel gene family are likely to encode a diverse family of odorant receptors.
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“These genes are expressed in VSNs and are similar in apparent transmembrane organization to olfactory receptor genes (Buck and Axel, 1991), but differ in much of their DNA sequence.”
From Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases (2001) · cites this paper as Buck and Axel, 1991
Citations
Cites
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,460
Somatic generation of antibody diversity
Tonegawa, S. (1983) · Nature · doi:10.1038/302575a0 · Cited by 4,005
Somatic generation of antibody diversity.
Matthyssens, G., Hozumi, N., & Tonegawa, S. (1976) · PubMed · Cited by 3,237
Molecular Genetics of Human Color Vision: The Genes Encoding Blue, Green, and Red Pigments
Nathans, J., Thomas, D., & Hogness, D. S. (1986) · Science · doi:10.1126/science.2937147 · Cited by 1,732
Identification of a Family of Muscarinic Acetylcholine Receptor Genes
Bonner, T. I., Buckley, N. J., Young, A. C., & Brann, M. R. (1987) · Science · doi:10.1126/science.3037705 · Cited by 1,423
A cyclic nucleotide-gated conductance in olfactory receptor cilia
Nakamura, T., & Gold, G. H. (1987) · Nature · doi:10.1038/325442a0 · Cited by 1,154
Graziadei, P. P. C., & Graziadei, G. A. M. (1979) · Journal of Neurocytology · doi:10.1007/bf01206454 · Cited by 1,006
G olf : an Olfactory Neuron Specific-G Protein Involved in Odorant Signal Transduction
Jones, D. T., & Reed, R. R. (1989) · Science · doi:10.1126/science.2499043 · Cited by 888
Kobilka, B. K., Kobilka, T. S., Daniel, K. W., Regan, J. W., Caron, M. G., & Lefkowitz, R. J. (1988) · Science · doi:10.1126/science.2836950 · Cited by 763
Research works printed but not linked: 1
- Rushton, 1965, Foveal photopigments in normal and colourblind, J. Physiol., 129, 41
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Gold, J. I., & Shadlen, M. N. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.113038 · Cited by 3,764
Kiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell · doi:10.1016/j.cell.2005.05.026 · Cited by 3,168
RAG-1-deficient mice have no mature B and T lymphocytes
Mombaerts, P., Iacomini, J., Johnson, R. S., Herrup, K., Tonegawa, S., & Papaioannou, V. E. (1992) · Cell · doi:10.1016/0092-8674(92)90030-g · Cited by 2,898
Combinatorial Receptor Codes for Odors
Malnic, B., Hirono, J., Sato, T., & Buck, L. B. (1999) · Cell · doi:10.1016/s0092-8674(00)80581-4 · Cited by 2,302
Self-citationVisualizing an Olfactory Sensory Map
Mombaerts, P., Wang, F., Dulac, C. G., Chao, S. K., Nemes, A., Mendelsohn, M. M., Edmondson, J., & Axel, R. (1996) · Cell · doi:10.1016/s0092-8674(00)81387-2 · Cited by 1,992
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Metadata
- Authors
- Buck, L., & Axel, R.
- Affiliations
- Columbia University (US)
- Howard Hughes Medical Institute (US)
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1991-04
- Volume
- 65
- Issue
- 1
- Pages
- 175-187
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2097186487
- Cited by
- 4,987
- References
- 45
- Citations by year
- 2026: 90 · 2025: 176 · 2024: 185 · 2023: 162 · 2022: 165 · 2021: 150 · 2020: 207 · 2019: 163 · 2018: 149 · 2017: 171 · 2016: 182 · 2015: 212 · 2014: 176 · 2013: 186 · 2012: 159
- FWCI
- 60.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (P01-CA23767, P01CA023767)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
- Life Sciences › Neuroscience › Sensory Systems › Ion Channels and Receptors
- Keywords
- olfactory receptors, gene family, olfactory sensory neurons, olfactory epithelium, seven-transmembrane proteins, odorant recognition, olfaction, gene cloning, ligand-gated receptors
- MeSH terms
- Amino Acid Sequence, Animals, Base Sequence, Cloning, Molecular, DNA, Biological Evolution, Multigene Family, Membrane Proteins, Molecular Sequence Data, Olfactory Pathways, Organ Specificity, Protein Conformation, Rats, Inbred Strains, Sensory Receptor Cells, Smell, Blotting, Southern, Blotting, Northern, Gene Expression, Polymerase Chain Reaction, Rats
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