The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development
Open accessAbstract
Reduced protein kinase A (PKA) activity in anterior imaginal disc cells leads to cell-autonomous induction of decapentaplegic (dpp), wingless (wg), and patched (ptc) transcription that is independent of hedgehog (hh) gene activity. The resulting nonautonomous adult wing and leg pattern duplications are largely due to induced dpp and wg expression and resemble phenotypes elicited by ectopic hh expression. Inhibition of PKA in anterior cells close to the posterior compartment can substitute for hh activity to promote growth of imaginal discs, whereas overexpression of PKA can counteract transcriptional induction of ptc by hh in these cells. PKA therefore appears to be an integral component of the mechanism by which hh regulates the expression of key patterning molecules in imaginal discs.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Lee, J. J., von Kessler, D. P., Parks, S., & Beachy, P. A. (1992) · Cell · doi:10.1016/0092-8674(92)90264-d · Cited by 581
Allocation of the thoracic imaginal primordia in the Drosophila embryo
Cohen, B., Simcox, A. A., & Cohen, S. M. (1993) · Development · doi:10.1242/dev.117.2.597 · Cited by 247
Cited by
Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing
Zecca, M., Basler, K., & Struhl, G. (1995) · Development · doi:10.1242/dev.121.8.2265 · Cited by 494
Sonic Hedgehog-induced Activation of the Gli1Promoter Is Mediated by GLI3
Dai, P., Akimaru, H., Tanaka, Y., Maekawa, T., Nakafuku, M., & Ishii, S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.12.8143 · Cited by 466
Price, M. A., & Kalderon, D. (2002) · Cell · doi:10.1016/s0092-8674(02)00664-5 · Cited by 381
Self-citationGli Protein Activity Is Controlled by Multisite Phosphorylation in Vertebrate Hedgehog Signaling
Niewiadomski, P., Kong, J. H., Ahrends, R., Ma, Y., Humke, E. W., Khan, S., Teruel, M. N., Novitch, B. G., & Rohatgi, R. (2014) · Cell Reports · doi:10.1016/j.celrep.2013.12.003 · Cited by 239
Genetic modifiers of tauopathy in Drosophila
Shulman, J. M., & Feany, M. B. (2003) · Genetics · doi:10.1093/genetics/165.3.1233 · Cited by 256
Metadata
- Authors
- Li, W., Ohlmeyer, J. T., Lane, M. E., & Kalderon, D.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1995-02
- Volume
- 80
- Issue
- 4
- Pages
- 553-562
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2041970325
- Cited by
- 316
- References
- 2
- FWCI
- 11.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development. https://app.cochat.ai/papers/10.1016/0092-8674(95)90509-x
- The paper
- Li, W., Ohlmeyer, J. T., Lane, M. E., & Kalderon, D. (1995). Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development. Cell. https://doi.org/10.1016/0092-8674(95)90509-x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
