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Jejunal efflux in short bowel syndrome
Abstract
24 h oral intake and intestinal output were studied in 15 patients with a short residual length of jejunum and no colon. 8 patients showed a net secretory, and 7 a net absorptive response to food. In secretors, daily intestinal output exceeded oral intake (mean 2.3 kg wet weight, and 233 mmol sodium). Long-term parenteral fluid and electrolyte replacements were needed only in those with a secretory response. Jejunal length inversely correlated with net intestinal output of fluid, sodium, potassium, and with percentage energy absorption. A secretory response was observed if jejunal length was less than 100 cm and was reduced by gastric antisecretory drugs and octreotide.
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“Management of patients with SBS can be challenging, especially in case of ostomies with associated large fluid losses and electrolyte imbalances [148].”
From Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery. (2022) · cites this paper as [148]
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Metadata
- Authors
- Nightingale, J. M. D., Lennard-Jones, J. E., Walker, E. R., & Farthing, M.
- Affiliations
- St Mark's Hospital (GB)
- ORCID
- Nightingale, J.M.D.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1990-09
- Volume
- 336
- Issue
- 8718
- Pages
- 765-768
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1980944037
- Cited by
- 218
- References
- 12
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 6 · 2023: 13 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 8 · 2016: 9 · 2015: 2 · 2014: 11 · 2013: 2 · 2012: 4
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Keywords
- short bowel syndrome, intestinal secretion, intestinal absorption, sodium loss, potassium excretion, energy absorption, octreotide
- MeSH terms
- Administration, Oral, Adult, Female, Food, Humans, Injections, Intravenous, Intestinal Absorption, Jejunostomy, Jejunum, Malabsorption Syndromes, Male, Middle Aged, Omeprazole, Parenteral Nutrition, Potassium, Ranitidine, Short Bowel Syndrome, Sodium, Octreotide
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