Cited by 218Clinical Nutrition and GastroenterologyGastrointestinal motility and disordersEnhanced Recovery After Surgery

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Jejunal efflux in short bowel syndrome

Nightingale, J.M.D., Lennard-Jones, J.E., Walker, E.R., Farthing, MJG·1990·The Lancet

DOI 10.1016/0140-6736(90)93238-k

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Abstract

24 h oral intake and intestinal output were studied in 15 patients with a short residual length of jejunum and no colon. 8 patients showed a net secretory, and 7 a net absorptive response to food. In secretors, daily intestinal output exceeded oral intake (mean 2.3 kg wet weight, and 233 mmol sodium). Long-term parenteral fluid and electrolyte replacements were needed only in those with a secretory response. Jejunal length inversely correlated with net intestinal output of fluid, sodium, potassium, and with percentage energy absorption. A secretory response was observed if jejunal length was less than 100 cm and was reduced by gastric antisecretory drugs and octreotide.

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Authors: Nightingale, J. M. D., Lennard-Jones, J. E., Walker, E. R., & Farthing, M.
Affiliations: St Mark's Hospital (GB)
ORCID: Nightingale, J.M.D.
Venue: The Lancet
Publisher: Elsevier BV
Published: 1990-09
Volume: 336
Issue: 8718
Pages: 765-768
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/0140-6736(90)93238-k
OpenAlex: W1980944037
Cited by: 218
References: 12
Citations by year: 2026: 3 · 2025: 3 · 2024: 6 · 2023: 13 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 8 · 2016: 9 · 2015: 2 · 2014: 11 · 2013: 2 · 2012: 4
FWCI: 5.16
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
Keywords: short bowel syndrome, intestinal secretion, intestinal absorption, sodium loss, potassium excretion, energy absorption, octreotide
MeSH terms: Administration, Oral, Adult, Female, Food, Humans, Injections, Intravenous, Intestinal Absorption, Jejunostomy, Jejunum, Malabsorption Syndromes, Male, Middle Aged, Omeprazole, Parenteral Nutrition, Potassium, Ranitidine, Short Bowel Syndrome, Sodium, Octreotide

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Jejunal efflux in short bowel syndrome

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