Cited by 843Lipoproteins and Cardiovascular HealthCholesterol and Lipid MetabolismCoronary Interventions and Diagnostics

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Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas' Atherosclerosis Regression Study (STARS)

Watts, G.F, Lewis, B, Lewis, E.S, Coltart, D.J, Smith, L.D.R, Swan, A.V, Brunt, J.N.H, Mann, J.I·1992·The Lancet

DOI 10.1016/0140-6736(92)90863-x

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Abstract

To assess the effect of dietary reduction of plasma cholesterol concentrations on coronary atherosclerosis, we set up a randomised, controlled, end-point-blinded trial based on quantitative image analysis of coronary angiograms in patients with angina or past myocardial infarction. Another intervention group received diet and cholestyramine, to determine the effect of a greater reduction in circulating cholesterol concentrations. 90 men with coronary heart disease (CHD), who had a mean (SD) plasma cholesterol of 7.23 (0.77) mmol/l were randomised to receive usual care (U, controls), dietary intervention (D), or diet plus cholestyramine (DC), with angiography at baseline and at 39 (SD 3.5) months. Mean plasma cholesterol during the trial period was 6.93 (U), 6.17 (D), and 5.56 (DC) mmol/l. The proportion of patients who showed overall progression of coronary narrowing was significantly reduced by both interventions (U 46%, D 15%, DC 12%), whereas the proportion who showed an increase in luminal diameter rose significantly (U 4%, D 38%, DC 33%). The mean absolute width of the coronary segments (MAWS) studied decreased by 0.201 mm in controls, increased by 0.003 mm in group D, and increased by 0.103 mm in group DC (p less than 0.05), with improvement also seen in the minimum width of segments, percentage diameter stenosis, and edge-irregularity index in intervention groups. The change in MAWS was independently and significantly correlated with LDL cholesterol concentration and L…

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Brown, G., Albers, J. J., Fisher, L. D., Schaefer, S. M., Lin, J.-T., Kaplan, C., Zhao, X.-Q., Bisson, B. D., Fitzpatrick, V. F., & Dodge, H. T. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011083231901 · Cited by 2,159
Can lifestyle changes reverse coronary heart disease?
Ornish, D., Brown, S. E., Billings, J. H., Scherwitz, L. W., Armstrong, W. T., Ports, T. A., McLanahan, S. M., Kirkeeide, R. L., Gould, K. L., & Brand, R. J. (1990) · The Lancet · doi:10.1016/0140-6736(90)91656-u · Cited by 2,110
Effect of Partial Ileal Bypass Surgery on Mortality and Morbidity from Coronary Heart Disease in Patients with Hypercholesterolemia: Report of the Program on the Surgical Control of the Hyperlipidemias (POSCH)
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Show all 3 references

Research works printed but not linked: 28

Study Group, 1988, The treatment of hyperlipidaemia in adults. Recommendations of the European Atherosclerosis Society, Eur Heart J, 8, 277
Duffield, 1983, Treatment of hyperlipidaemia retards progression of symptomatic femoral atherosclerosis, Lancet, ii, 639, 10.1016/S0140-6736(83)92527-8 · DOI
Amtzenius, 1985, Diet, lipoproteins, and the progression of coronary atherosclerosis, N Engl J Med, 312, 805, 10.1056/NEJM198503283121301 · DOI
Blankenhom, 1990, The influence of diet on the appearance of new lesions in human coronary arteries, JAMA, 263, 1646, 10.1001/jama.263.12.1646 · DOI
Lewis, 1974, Serum lipoprotein abnormalities in patients with ischaemic heart disease: comparisons with a control population, Br Med J, iii, 489, 10.1136/bmj.3.5929.489 · DOI
Campeau, 1976, Grading of angina pectoris, Circulation, 54, 522, 10.1161/circ.54.3.947585 · DOI
Austen, 1975, AHA committee report. A reporting system on patients evaluated for coronary artery disease, Circulation, 51, 7, 10.1161/01.CIR.51.4.5 · DOI
Colchester, 1983, Measurement of vessel calibre and volume blood flow by dynamic quantitative digital angiography: an initial application showing variation of cerebral artery diameter with PaCO2, J Cerebr Blood Flow Metab, 3, S640
Jnh Brunt, Design, implementation, validation and use of a system for quantitative coronary cineangiography ((Rotterdam, 1989) 32 (abstr)), Third international symposium on coronary arteriography.
Brown, 1982, Arteriographic assessment of coronary atherosclerosis, Arteriosclerosis, 2, 2, 10.1161/01.ATV.2.1.2 · DOI
Crawford, 1977, Computer densitometry for angiographic assessment of arterial cholesterol content and gross pathology in human atherosclerosis, J Lab Clin Med, 89, 378
Blankenhorn, 1991, Effects of colestipolniacin therapy on human femoral atherosclerosis, Circulation, 83, 438, 10.1161/01.CIR.83.2.438 · DOI
Blankenhorn, 1987, Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts, JAMA, 257, 3233, 10.1001/jama.257.23.3233 · DOI
Kane, 1990, Regression of coronary atherosclerosis during treatment of familial hypercholesterolaemia with combined drug regimens, JAMA, 264, 1007, 10.1001/jama.264.23.3007 · DOI
Wissler, 1976, Studies of regression of advanced atherosclerosis in experimental animals and men, Ann NY Acad Sci, 275, 363, 10.1111/j.1749-6632.1976.tb43368.x · DOI
La Ville, 1989, Primary prevention of atherosclerosis by lovastatin in a genetically hyperlipidaemic rabbit strain, Atherosclerosis, 78, 205, 10.1016/0021-9150(89)90224-4 · DOI
Habib, 1984, Atherosclerosis impairs endothelium-dependent arterial relaxation, Circulation, 70, 123
Vita, 1990, Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease, Circulation, 81, 491, 10.1161/01.CIR.81.2.491 · DOI
Harrison, 1987, Restoration of endothelium-dependent arterial relaxation by dietary treatment of atherosclerosis, Circulation, 80, 1808
Vartiainen, 1947, Arteriosclerosis and wartime, Ann Med Intern Fen, 34, 705
Wilens, 1947, The resorption of arterial atheromatous deposits in wasting disease, Am J Pathol, 33, 793
Lewis, 1981, Towards an improved lipid-lowering diet: additive effects of changes in nutrient intake, Lancet, ii, 1310, 10.1016/S0140-6736(81)91339-8 · DOI
Choudhury, 1984, A multifactorial diet in the management of hyperlipidaemia, Atherosclerosis, 50, 93, 10.1016/0021-9150(84)90011-X · DOI
Lipid Research Clinics Program, 1984, The Lipid Research Clinics coronary primary prevention trial results, I. Reduction in incidence of coronary heart disease, JAMA, 251, 351, 10.1001/jama.251.3.351 · DOI · Paper page
Brensike, 1984, Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI type II coronary intervention study, Circulation, 69, 313, 10.1161/01.CIR.69.2.313 · DOI
Ambrose, 1988, Angiographic progression of coronary artery disease and the development of myocardial infarction, J Am Coll Cardiol, 12, 56, 10.1016/0735-1097(88)90356-7 · DOI
Hackett, 1989, Coronary stenoses before and after acute myocardial infarction, Am J Cardiol, 63, 1517, 10.1016/0002-9149(89)90018-0 · DOI
Roussouw, 1990, The value of lowering cholesterol after myocardial infarction, N Engl J Med, 323, 1112, 10.1056/NEJM199010183231606 · DOI

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Watts, G., Gwilym, R. M. A., Mazurkiewicz, J., & Coltart, J. (1995) · Diabetes Care · doi:10.2337/diacare.18.2.234 · Cited by 36
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Chan, S. Y., Mancini, G. B. J., Burns, S., Johnson, F. F., Brozic, A. P., Kingsbury, K., Barr, S., Kuramoto, L., Schulzer, M., Frohlich, J., et al. (2006) · Journal of Cardiopulmonary Rehabilitation (JCR) · doi:10.1097/00008483-200609000-00002 · Cited by 31
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Merz, C. N. B., Rozanski, A., & Forrester, J. S. (1997) · The American Journal of Medicine · doi:10.1016/s0002-9343(97)00046-6 · Cited by 47
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Wolff, S., & Nourooz-Zadeh, J. (1996) · Atherosclerosis · doi:10.1016/0021-9150(95)05640-8 · Cited by 31
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Wang, Y., Fang, Y., Witting, P. K., Charchar, F. J., Sobey, C. G., Drummond, G. R., & Golledge, J. (2023) · Scientific Reports · doi:10.1038/s41598-023-28738-2 · Cited by 30
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Roberts, W. C. (1993) · The American Journal of Cardiology · doi:10.1016/0002-9149(93)90898-m · Cited by 30
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Lim, H., Choi, Y. M., & Choue, R. (2008) · Nutrition Research · doi:10.1016/j.nutres.2008.08.005 · Cited by 28
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Watts, G. F., Mandalia, S., Slavin, B., Brunt, J., Coltart, D., & Lewis, B. (1994) · Clinical Chemistry · doi:10.1093/clinchem/40.12.2240 · Cited by 28
Self-citation
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Endothelial dysfunction and dyslipidemia: possible effects of lipid lowering and lipid modifying therapy.
van Boven, A. J., Jukema, J., & Paoletti, R. (1994) · Pharmacological Research · doi:10.1016/1043-6618(94)80049-9 · Cited by 27
Low blood total cholesterol and mortality: causality, consequence and confounders.
Lewis, B. J., & Tikkanen, M. J. (1994) · American Journal of Cardiology · doi:10.1016/0002-9149(94)90731-5 · Cited by 27
Self-citation
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Han, S. N., Leka, L. S., Lichtenstein, A. H., Ausman, L. M., & Meydani, S. N. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m300181-jlr200 · Cited by 26
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Gould, K. L. (1998) · The American Journal of Medicine · doi:10.1016/s0002-9343(98)00140-5 · Cited by 25
Letters to the Editor
O'Flaherty, D., & Adams, A. (1993) · Journal of the Royal Society of Medicine · doi:10.1177/014107689308600328
Therapeutic lifestyle change and adult treatment panel III: Evidence then and now
Stone, N. J., & Horn, L. V. (2002) · Current Atherosclerosis Reports · doi:10.1007/s11883-002-0047-x · Cited by 26
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Korpilahti, K. (1998) · European Heart Journal · doi:10.1053/euhj.1997.0869 · Cited by 20
Quantitative ultrasonic characterization of lesion composition and remodeling in atherosclerotic rabbit aorta.
Wickline, S. A., Shepard, R., & Daugherty, A. (1993) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.13.10.1543 · Cited by 25
Focus on lifestyle change and the metabolic syndrome
Stone, N. J. (2004) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2004.03.009 · Cited by 28
“This diet was associated with weight reduction and a reduction in low-density lipoprotein cholesterol (LDL-C), which led to improvement on coronary angiography that rivaled the drugtreatment group [13].”
Background
Effecacy of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors for prevention of stroke
Warshafsky, S., Packard, D., Marks, S., Sachdeva, N., Terashita, D., Kaufman, G., Sang, K., Deluca, A., Peterson, S. J., & Frishman, W. (1999) · Journal of general internal medicine · doi:10.1046/j.1525-1497.1999.02109.x · Cited by 24
Effect of HELP-LDL-apheresis on outcomes in patients with advanced coronary atherosclerosis and severe hypercholesterolemia.
Park, J.-W., Merz, M., & Braun, P. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00092-6 · Cited by 24
Do codeine and caffeine enhance the analgesic effect of aspirin?-A systematic overview
Zhang, W., & Po, A. L. W. (1997) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/j.1365-2710.1997.tb00002.x · Cited by 49
A study to determine the response of coronary atherosclerosis to raising low high density lipoprotein cholesterol with a fibric-acid derivative in men after coronary bypass surgery
Syvänne, M., Taskinen, M., Nieminen, M. S., Manninen, V., Kesäniemi, Y. A., Pasternack, A. I., Nawrocki, J. W., Haber, H. E., & Frick, M. H. (1997) · Controlled Clinical Trials · doi:10.1016/s0197-2456(96)00091-8 · Cited by 22
Determinants of compliance in men enrolled in a diet and exercise intervention trial: a randomized, controlled study
Näslund, G. K., Fredrikson, M. G., Hellénius, M.-L., & Fairé, U. D. (1996) · Patient Education and Counseling · doi:10.1016/s0738-3991(96)00917-2 · Cited by 18
Review of cholesterol-lowering therapy: Coronary angiographic and events trials
Waters, D. D., & Pedersen, T. R. (1996) · The American Journal of Medicine · doi:10.1016/s0002-9343(96)00318-x · Cited by 22
Issues In Fat Replacement
Jones, S. (1996) · doi:10.1201/9781420048971.pt1 · Cited by 24
Effect of cholesterol reduction by simvastatin on progression of coronary atherosclerosis: Design, baseline characteristics, and progress of the Multicenter Anti-Atheroma Study (MAAS)
Dumont, J. (1993) · Controlled Clinical Trials · doi:10.1016/0197-2456(93)90004-w · Cited by 26
Replacing Saturated Fat With Unsaturated Fat in Western Diet Reduces Foamy Monocytes and Atherosclerosis in Male Ldlr –/– Mice
Lian, Z., Perrard, X. D., Peng, X., Raya, J. L., Hernandez, A. A., Johnson, C. G., Lagor, W. R., Pownall, H. J., Hoogeveen, R. C., Simon, S. I., et al. (2019) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.119.313078 · Cited by 28
Antiatherosclerotic and antiatherogenic effects of a calcium antagonist plus statin combination: amlodipine and lovastatin.
Orekhov, A. N., Tertov, V., Sobenin, I., Akhmedzhanov, N., & Pivovarova, E. M. (1997) · International Journal of Cardiology · doi:10.1016/s0167-5273(97)00243-x · Cited by 23
LIPID LOWERING
Pearson, T. A., & Swan, H. J. C. (1996) · Cardiology Clinics · doi:10.1016/s0733-8651(05)70265-4 · Cited by 7
The effect of LDL apheresis on progression of coronary artery disease in patients with familial hypercholesterolemia
Waidner, T., Franzen, D., Voelker, W., Ritter, M., Borberg, H., Hombach, V., & Höpp, H. (1994) · Clinical Investigation · doi:10.1007/bf00190741 · Cited by 23
Patient-Directed, Nonprescription Approaches to Cardiovascular Disease
Simon, H. B. (1994) · Archives of Internal Medicine · doi:10.1001/archinte.154.20.2283 · Cited by 15
Treatment of primary hypercholesterolemia: Fluvastatin versus bezafibrate
Greten, H., Beil, F. U., Schneider, J. E., Weisweiler, P., Armstrong, V. W., Keller, C., Klör, H., von Hodenberg, E., Weidinger, G., Eskötter, H., et al. (1994) · The American Journal of Medicine · doi:10.1016/0002-9343(94)90233-x · Cited by 21
Randomized trials of replacing saturated fatty acids with n-6 polyunsaturated fatty acids in coronary heart disease prevention: Not the gold standard?
Virtanen, J. K. (2018) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2018.04.002 · Cited by 25
Beyond Cholesterol Lowering: Pleiotropic Effects of Bile Acid Binding Resins Against Cardiovascular Disease Risk Factors in Patients with Metabolic Syndrome
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“Thomas’ Atherosclerosis Regression Study (STARS) compared, in 90 men with coronary artery disease, the effects of dietary intervention or diet combined with cholestyramine treatment on angiographic progression after 39 months [22].”
BackgroundResult
Failure of internal thoracic artery grafts: conclusions from coronary angiography mid-term follow-up.
Bezon, E., Choplain, J., Maguid, Y. A., Aziz, A., & Barra, J. (2003) · Annals of Thoracic Surgery · doi:10.1016/s0003-4975(03)00550-2 · Cited by 22
Quantitative coronary angiography in regression trials: a review of methodologic considerations, endpoint selection, and limitations
Lansky, A. J., Desai, K., & Leon, M. B. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(01)02326-8 · Cited by 20
A case-management program of medium intensity does not improve cardiovascular risk factor control in coronary artery disease patients: the Heartcare I Trial
Nordmann, A. J., Heilmbauer, I., Walker, T., Martina, B., & Battegay, E. (2001) · The American Journal of Medicine · doi:10.1016/s0002-9343(01)00682-9 · Cited by 20
Modification of coronary artery disease progression by cholesterol-lowering therapy
Archbold, A., & Timmis, A. (1999) · Current Opinion in Lipidology · doi:10.1097/00041433-199912000-00008 · Cited by 20
Trace elements in coronary heart disease
Krachler, M., Lindschinger, M., Eber, B., Watzinger, N., & Wallner, S. (1997) · Biological Trace Element Research · doi:10.1007/bf02784438 · Cited by 38
Angiographic trials of lipid-lowering therapy: end of an era?
Thompson, G. R. (1995) · Heart · doi:10.1136/hrt.74.4.343 · Cited by 22
Lipid risk factors and the regression of atherosclerosis.
Gotto, A. (1995) · American Journal of Cardiology · doi:10.1016/s0002-9149(05)80009-8 · Cited by 22
A randomized pilot trial of low‐dose combination lipid‐lowering therapy following coronary artery bypass grafting
Barbir, M., Hunt, B., Galloway, D., Taylor, A., Ilsley, C., Mitchell, A. G., & Yacoub, M. (1994) · Clinical Cardiology · doi:10.1002/clc.4960170204 · Cited by 22
EFFECTS OF DIETARY MODIFICATION AND TREATMENT OF OBESITY
Stone, N. J., & Kushner, R. F. (2000) · Medical Clinics of North America · doi:10.1016/s0025-7125(05)70209-1 · Cited by 19
Macronutrient replacement options for saturated fat
Flock, M. R., Fleming, J. A., & Kris‐Etherton, P. M. (2013) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000039 · Cited by 22
Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity.
Meissner, M., Wolters, H., de Boer, R. D., Havinga, R., Boverhof, R., Bloks, V., Kuipers, F., & Groen, A. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.02.021 · Cited by 21
Retardation of Coronary Atherosclerosis: The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT) and Other Angiographic Trials
de Faire, U., Ericsson, C., Grip, L., Nilsson, J., Svane, B., & Hamsten, A. (1997) · Cardiovascular Drugs and Therapy · doi:10.1023/a:1007787713191 · Cited by 21
High dose of fluvastatin sodium (XU62-320), a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, lowers plasma cholesterol levels in homozygous Watanabe-heritable hyperlipidemic rabbits.
Kurokawa, J., Hayashi, K., Toyota, Y., Shingu, T., Shiomi, M., & Kajiyama, G. (1995) · Biochimica et Biophysica Acta · doi:10.1016/0005-2760(95)00155-6 · Cited by 21
Overview
Shintani, T. T., & Hughes, C. (1994) · Journal of Cardiovascular Risk · doi:10.1177/174182679400100102 · Cited by 21
The rapid reduction in cardiac events with lipid-lowering therapy: mechanisms and implications.
Pearson, T. A., & Marx, H. J. (1993) · American Journal of Cardiology · doi:10.1016/0002-9149(93)90864-9 · Cited by 21
Screening for lipid disorders under health system reform.
Sox, H. C. (1993) · New England Journal of Medicine · doi:10.1056/nejm199304293281711 · Cited by 21
Clinical perspectives on primary and secondary prevention of coronary atherosclerosis
DEEDWANIA, P. C. (1995) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)30017-7 · Cited by 23
Relevance of Smooth Muscle Replication and Development to Vascular Disease
Schwartz, S., O'Brien, E., Deblois, D., & Giachelli, C. (1995) · Elsevier eBooks · doi:10.1016/b978-012632310-8/50005-x · Cited by 21
Protective effect of rutin and β-cyclodextrin against hepatotoxicity and nephrotoxicity induced by lambda-cyhalothrin in Wistar rats: biochemical, pathological indices and molecular analysis
Ali, W. A., Moselhy, W., Ibrahim, M., Amin, M., Kamel, S., & Eldomany, E. B. (2022) · Biomarkers · doi:10.1080/1354750x.2022.2087003 · Cited by 20
Interaction of genotype and diet on small intestine microbiota of Japanese quail fed a cholesterol enriched diet
Liu, S., Tun, H. M., Leung, F. C.-C., Bennett, D. C., Zhang, H., & Cheng, K. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-20508-9 · Cited by 20
“Raw sequences were filtered to meet the following quality criteria: (1) complete barcode sequences followed by a forward primer sequence, with no mismatch in either barcode or primer sequence; (2) reads lengths between 150 and 900 bases; (3) average quality score >25; and (4) homophlymer run of 8 nt.”
Method
Changing health behaviors to improve health outcomes after angioplasty: a randomized trial of net present value versus future value risk communication
Charlson, M. E., Peterson, J. C., Boutin‐Foster, C., Briggs, W. M., Ogedegbe, G. G., McCulloch, C. E., Hollenberg, J. P., Wong, C., & Allegrante, J. P. (2007) · Health Education Research · doi:10.1093/her/cym068 · Cited by 18
“At least two studies have shown that intensive lipid-lowering therapy can result in regression of disease [6, 7].”
Background
Dietary fat and cardiovascular disease: putting the Women's Health Initiative in perspective.
Howard, B. (2007) · NMCD. Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2006.10.006 · Cited by 20
Women's Angiographic Vitamin and Estrogen trial:
Hsia, J. A., Alderman, E. L., Verter, J. I., Rogers, W. J., Thompson, P. D., Howard, B. V., Cobb, F. R., Ouyang, P., Tardif, J., Higginson, L., et al. (2002) · Controlled Clinical Trials · doi:10.1016/s0197-2456(02)00237-4 · Cited by 24
Improving health behaviors and outcomes after angioplasty: using economic theory to inform intervention
Charlson, M. E. (2002) · Health Education Research · doi:10.1093/her/17.5.606 · Cited by 20
“…generally have been successful in lowering event rates in the treatment D ow nloaded from https://academ ic.oup.com /her/article-abstract/17/5/606/609458 by guest on 02 M arch 2019 groups (Brown et al., 1990; Buchwald et al., 1990; Ornish et al., 1990; Schuler et al., 1992; Watts et al., 1992).”
Background
Effects of a National Cholesterol Education Program Step II Diet on apolipoprotein A-IV metabolism within triacylglycerol-rich lipoproteins and plasma.
Sun, Z.-Y., Welty, F., Dolnikowski, G., Lichtenstein, A., & Schaefer, E. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.3.308 · Cited by 20
Cholesterol lowering and coronary artery disease: mechanisms of risk reduction
Archbold, A., & Timmis, A. (1998) · Heart · doi:10.1136/hrt.80.6.543 · Cited by 19
“Cardiac events have been reduced by lipid lowering interventions other than statins, 43–45 but fewer events and smaller populations make comparisons with the statin trials di Y cult.”
The retardation of progression, stabilization, and regression of coronary and carotid atherosclerosis by low-density lipoprotein apheresis in patients with familial hypercholesterolemia.
Koga, N. (1997) · Therapeutic apheresis · doi:10.1111/j.1744-9987.1997.tb00149.x · Cited by 20
Management of Lipid Disorders in the Elderly
Playford, D. A., & Watts, G. F. (1997) · Drugs & Aging · doi:10.2165/00002512-199710060-00005 · Cited by 16
Self-citation
Review of the major intervention trials of lowering coronary artery disease risk through cholesterol reduction.
Stark, R. M. (1996) · American Journal of Cardiology · doi:10.1016/s0002-9149(96)00657-1 · Cited by 20
Pravastatin experience in elderly and non-elderly patients
Mellies, M. J., DeVault, A. R., Kassler-Taub, K., McGovern, M. E., & Pan, H. (1993) · Atherosclerosis · doi:10.1016/0021-9150(93)90105-4 · Cited by 21
Health problems associated with saturated and trans fatty acids intake
Zock, P. L. (2006) · Elsevier eBooks · doi:10.1533/9781845691073.1.3 · Cited by 23
Dietary Counselling for Dyslipidemia in Primary Care: Results of a Randomized Trial
Reid, R. D., Fodor, G. J., Lydon-Hassen, K., D’Angelo, M. S., McCrea, J., Bowlby, M. C., & DiFrancesco, L. (2002) · Canadian Journal of Dietetic Practice and Research · doi:10.3148/63.4.2002.169 · Cited by 15
Can improved quality of care reduce the costs of managing angina pectoris?
Cleland, J. (1996) · European Heart Journal · doi:10.1093/eurheartj/17.suppl_a.29 · Cited by 19
Factors Influencing Coronary Artery Bypass Graft Patency
Metcalfe, M., Lip, G., & Dargie, H. (1994) · Cardiovascular surgery · doi:10.1177/096721099400200602 · Cited by 19
Coronary angiography: more than meets the eye.
Applegate, R. J., Herrington, D. M., & Little, W. C. (1993) · Circulation · doi:10.1161/01.cir.87.4.1399 · Cited by 19
Dietary intake of patients with angiographically defined coronary artery disease and that of healthy controls in Iran
Nazeminezhad, R., Tajfard, M., Latiff, L. A., Mouhebati, M., Esmaeily, H., Ferns, G. A., Ghayour‐Mobarhan, M., & Rahimi, H. R. (2013) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2013.205 · Cited by 19
Lipid-Lowering Therapy and Progression of Coronary Atherosclerosis
Bruschke, A. V., Reiber, J., Kong, L. I., & Wellens, H. (1996) · Developments in Cardiovascular Medicine · doi:10.1007/978-94-009-0143-8 · Cited by 19
Reversing Heart Disease
SHERMAN, C. (1994) · The Physician and Sportsmedicine · doi:10.1080/00913847.1994.11710449 · Cited by 5

Authors: Watts, G. F., Lewis, B., Lewis, E. S., Coltart, D. J., Smith, L. D. R., Swan, A. V., Brunt, J. N. H., & Mann, J. I.
Affiliations: St Thomas' Hospital (GB)
University of Manchester (GB)
University of Otago (NZ)
ORCID: Watts, G.F
Lewis, B
Venue: The Lancet
Publisher: Elsevier BV
Published: 1992-03
Volume: 339
Issue: 8793
Pages: 563-569
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/0140-6736(92)90863-x
OpenAlex: W2132942256
Cited by: 843
References: 34
Citations by year: 2026: 2 · 2025: 4 · 2024: 9 · 2023: 8 · 2022: 4 · 2021: 5 · 2020: 8 · 2019: 6 · 2018: 9 · 2017: 7 · 2016: 9 · 2015: 10 · 2014: 10 · 2013: 15 · 2012: 11
FWCI: 103.88
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Coronary Interventions and Diagnostics
Keywords: coronary artery disease, lipid-lowering diet, cholestyramine, dietary cholesterol reduction, coronary atherosclerosis regression, coronary angiography, coronary lumen diameter, LDL cholesterol, LDL/HDL ratio, cardiovascular events, hypercholesterolemia
MeSH terms: Angina Pectoris, Cholesterol, Cholestyramine Resin, Combined Modality Therapy, Coronary Artery Disease, Coronary Disease, Humans, Cholesterol, HDL, Cholesterol, LDL, Male, Middle Aged, Remission Induction, Treatment Outcome, Coronary Angiography

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Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas' Atherosclerosis Regression Study (STARS)

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