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Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat

Fulwiler, Carl E., Saper, Clifford B.·1984·Brain Research Reviews
DOI 10.1016/0165-0173(84)90012-2
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Abstract

In summary, we have demonstrated the subnuclear organization of PB, and correlated this with the origins of its efferent connections. In general, PBm projects primarily to the insular, infralimbic and lateral frontal cortex, and to associated areas in the thalamus, hypothalamus and amygdala. PBl chiefly innervates the autonomic nuclei of the hypothalamus and related portions of the amygdala and the bed nucleus of the stria terminalis. KF is the main source of descending projections from PB to the region of the nucleus of the solitary tract, the ventrolateral medulla and the intermediolateral cell column in the thoracic spinal cord. Further subnuclear organization of the origins of these projections within the major PB subdivisions has been described in detail. While PB afferents tend to terminate in specific subnuclei, one cannot reliably predict from the functional properties of the major inputs to a subnucleus what information will be carried in its efferents. Further anatomical and physiological studies of the input-output relationships of single PB neurons will be necessary to help resolve this enigma. However, recent immunohistochemical observations suggest that the subnuclear organization of PB afferent and efferent connections may reflect, at least in part, their biochemical specificity.

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Metadata

Authors
Fulwiler, C. E., & Saper, C. B.
Venue
Brain Research Reviews
Publisher
Elsevier BV
Published
1984-08
Volume
7
Issue
3
Pages
229-259
ISSN
0165-0173
DOI
10.1016/0165-0173(84)90012-2
Cited by
918
References
2
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. https://app.cochat.ai/papers/10.1016/0165-0173(84)90012-2
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Fulwiler, C. E., & Saper, C. B. (1984). Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brain Research Reviews. https://doi.org/10.1016/0165-0173(84)90012-2