Cited by 467Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on BehaviorDeep Brain Stimulation and Movement Disorders

The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.

Modulatory functions of neurotransmitters in the striatum: ACh/dopamine/NMDA interactions

Di Chiara, Gaetano, Morelli, Micaela, Consolo, Silvana·1994·Trends in Neurosciences

DOI 10.1016/0166-2236(94)90005-1

Open this paper in CoChat — free account

Abstract

The striatum is viewed as a structure performing fast neurotransmitter-mediated operations through somatotopically organized projections to medium-size spiny neurons. This view is contrasted with another view that depicts the striatum as a site of diffuse modulatory influences mediated by cholinergic interneurons and by dopamine and N-methyl-D-aspartate receptors. These two operational and organizational modes both contribute, through their mutual interaction, to the function of basal ganglia. Detailed knowledge of the neural mechanisms by which such interactions take place and are expressed into behaviour, can provide new insight into the physiopathology and new clues for therapy of disorders of basal ganglia.

Integrity signals

Registry

Crossref · 10.1016/0166-2236(94)90005-1

Cites

72 of 72 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527
The functional anatomy of basal ganglia disorders
Albin, R. L., Young, A. B., & Penney, J. B. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90074-x · Cited by 5,353
The Synaptic Organization of the Brain
(2004) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195159561.001.1 · Cited by 3,574
D 1 and D 2 Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons
Gerfen, C. R., Engber, T. M., Mahan, L. C., Susel, Z., Chase, T. N., Monsma, F. J., & Sibley, D. R. (1990) · Science · doi:10.1126/science.2147780 · Cited by 2,967
Brain dopamine receptors.
Seeman, P. M. (1980) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06839-5 · Cited by 1,888
Neurotransmitters and neuromodulators in the basal ganglia
Graybiel, A. M. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90104-i · Cited by 1,576
The neostriatal mosaic: multiple levels of compartmental organization
Gerfen, C. R. (1992) · Trends in Neurosciences · doi:10.1016/0166-2236(92)90355-c · Cited by 1,471
Muscarinic Receptor Subtypes
Hulme, E. C., Birdsall, N. J. M., & Buckley, N. J. (1990) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.30.040190.003221 · Cited by 1,366
The mysterious motor function of the basal ganglia
MARSDEN, C. D. (1982) · Neurology · doi:10.1212/wnl.32.5.514 · Cited by 924
SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems.
Iorio, L. C., Barnett, A., Leitz, F. H., Houser, V. P., & Korduba, C. A. (1983) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)21599-3 · Cited by 896

Show all 72 references

Research works printed but not linked: 17

Kitai, 1993, Adv. Neurol., 60, 40
Herrling, 1992, Arzneimit. Forsch. Drug Res., 42, 202
Morelli, 1992, J. Pharmacol. Exp. Ther., 260, 402
Meredithy, 1990, Neurology, 296, 204
Kimura, 1984, 81, 4998
Maura, 1988, J. Pharmacol. Exp. Ther., 247, 680
Jarvie, 1993, Adv. Neurol., 60, 325
Iorio, 1983, J. Pharmacol. Exp. Ther., 226, 462
Damsma, 1991, J. Pharmacol. Exp. Ther., 259, 1064
Imperato, 1993, J. Pharmacol. Exp. Ther., 366, 557
Meller, 1987, Mol. Pharmacol., 31, 592
Seeman, 1981, Pharmacol. Rev., 32, 229
Le Moine, 1990, 87, 230
Le Moine, 1991, 88, 4205
Di Chiara G.; Morelli M. Basal Ganglia IV, Proc. IVth Meeting Int. Basal Ganglia Society Percheron G.; McKenzie J.S. Plenum Press (in press.)
Di Chiara, 1993, Adv. Neurol., 60, 102
Riederer, 1993, Adv. Neurol., 60, 626

Sorted by citations

Items 101–200 of 467

Cholinergic modulation of nucleus accumbens medium spiny neurons
de Rover, M., Lodder, J. C., Kits, K. S., Schoffelmeer, A. N. M., & Brussaard, A. B. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02289.x · Cited by 96
Targeting striatal cholinergic interneurons in Parkinson's disease: Focus on metabotropic glutamate receptors
Pisani, A. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00137-0 · Cited by 94
The Muscarinic M1/M4 Receptor Agonist Xanomeline Exhibits Antipsychotic-Like Activity in Cebus apella Monkeys
Andersen, M. B., Fink‐Jensen, A., Peacock, L., Gerlach, J., Bymaster, F. P., Lundbæk, J. A., & Werge, T. M. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300151 · Cited by 93
The basal ganglia: anatomy, physiology, and pharmacology
Tisch, S. H., Silberstein, P., Limousin, P. D., & Jahanshahi, M. (2004) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2004.06.004 · Cited by 96
The Basal Ganglia
Haber, S. N., Adler, A., & Bergman, H. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-374236-0.10020-3 · Cited by 94
Alcohol and dopamine.
Chiara, G. D. (1997) · PubMed Central · Cited by 89
Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice
Miki, K., Ishibashi, S., Sun, L., Xu, H., Ohashi, W., Kuroiwa, T., & Mizusawa, H. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21925 · Cited by 89
Social play alters regional brain opioid receptor binding in juvenile rats
Vanderschuren, L. J. M. J., Stein, E. A., Wiegant, V. M., & Van Ree, J. M. (1995) · Brain Research · doi:10.1016/0006-8993(95)00256-p · Cited by 88
Functional organization of forebrain pathways for song production and perception
Margoliash, D. (1997) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(19971105)33:5 · Cited by 206
Food Addiction and Binge Eating: Lessons Learned from Animal Models
Novelle, M. G., & Diéguez, C. (2018) · Nutrients · doi:10.3390/nu10010071 · Cited by 90
Contribution of cholinergic interneurons to striatal pathophysiology in Parkinson's disease
Ztaou, S., & Amalric, M. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.02.019 · Cited by 88
The Melatonergic System in Mood and Anxiety Disorders and the Role of Agomelatine: Implications for Clinical Practice
Berardis, D. D., Marini, S., Fornaro, M., Srinivasan, V., Iasevoli, F., Tomasetti, C., Valchera, A., Perna, G., Quera-Salva, M.-A., Martinotti, G., et al. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140612458 · Cited by 86
Conditional Ablation of Striatal Neuronal Types Containing Dopamine D2 Receptor Disturbs Coordination of Basal Ganglia Function
Sano, H., Yasoshima, Y., Matsushita, N., Kaneko, T., Kohno, K., Pastan, I. H., & Kobayashi, K. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-27-09078.2003 · Cited by 84
Coordination of rapid cholinergic and dopaminergic signaling in striatum during spontaneous movement
Howe, M. W., Ridouh, I., Mascaro, A. L. A., Larios, A., Azcorra, M., & Dombeck, D. A. (2019) · eLife · doi:10.7554/elife.44903 · Cited by 84
Regulation of AMPA Receptors by Phosphorylation
Carvalho, A. L., Duarte, C. B., & Carvalho, A. P. (2000) · Neurochemical Research · doi:10.1023/a:1007644128886 · Cited by 87
Excitatory actions of serotonin on GABAergic neurons of the medial septum and diagonal band of broca
Alreja, M. (1996) · Synapse · doi:10.1002/(sici)1098-2396(199601)22:1 · Cited by 67
Modulation of levodopa-induced motor response complications by NMDA antagonists in Parkinson's disease
Blanchet, P. J., Papa, S. M., Metman, L. V., Mouradian, M. M., & Chase, T. N. (1997) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(96)00038-3 · Cited by 84
Immunolocalization of CB 1 receptor in rat striatal neurons: A confocal microscopy study
Fusco, F. R., Martorana, A., Giampà, C., March, Z. D., Farini, D., D’Angelo, V., Sancesario, G., & Bernardi, G. (2004) · Synapse · doi:10.1002/syn.20047 · Cited by 83
Type 2 Metabotropic Glutamate (mGlu) Receptors Tonically Inhibit Transmitter Release in Rat Caudate Nucleus: In Vivo Studies with (2S,1′S,2′S,3′R)‐2‐(2′‐carboxy‐3′‐phenylcyclopropyl)glycine, a New Potent and Selective Antagonist
Cozzi, A., Attucci, S., Peruginelli, F., Marinozzi, M., Luneia, R., Pellicciari, R., & Moroni, F. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01489.x · Cited by 78
Tremulous jaw movements induced by the acetylcholinesterase inhibitor tacrine: effects of antiparkinsonian drugs
Cousins, M. S., Carriero, D. L., & Salamone, J. D. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(97)00008-3 · Cited by 77
Substantia Nigra D1Receptors and Stimulation of Striatal Cholinergic Interneurons by Dopamine: A Proposed Circuit Mechanism
Abercrombie, E. D., & DeBoer, P. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-21-08498.1997 · Cited by 76
Muscarinic Acetylcholine Receptors Activate Expression of the Egr Gene Family of Transcription Factors
von der Kammer, H., Mayhaus, M., Albrecht, C., Enderich, J., Wegner, M., & Nitsch, R. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.23.14538 · Cited by 76
Dissociable effects of disconnecting amygdala central nucleus from the ventral tegmental area or substantia nigra on learned orienting and incentive motivation
El‐Amamy, H., & Holland, P. C. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05402.x · Cited by 75
Involvement of GABA and cholinergic receptors in the nucleus accumbens on feedback control of somatodendritic dopamine release in the ventral tegmental area
Rahman, S., & McBride, W. J. (2002) · Journal of Neurochemistry · doi:10.1046/j.0022-3042.2001.00739.x · Cited by 75
Reduced Density of Cholinergic Interneurons in the Ventral Striatum in Schizophrenia: An In Situ Hybridization Study
Holt, D. J., Bachus, S. E., Hyde, T. M., Wittie, M., Herman, M. M., Vangel, M. G., Saper, C. B., & Kleinman, J. E. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.007 · Cited by 74
Cholinergic Functioning in Stimulant Addiction
Sofuoglu, M., & Mooney, M. E. (2009) · CNS Drugs · doi:10.2165/11310920-000000000-00000 · Cited by 77
Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology
Yamada, M., Basile, A. S., Fedorova, I. D., Zhang, W., Duttaroy, A., Cui, Y., Lamping, K. G., Faraci, F. M., Deng, C., & Wess, J. (2003) · Life Sciences · doi:10.1016/j.lfs.2003.09.022 · Cited by 77
Adenosine A1 receptor blockade selectively potentiates the motor effects induced by dopamine D1 receptor stimulation in rodents
Popoli, P., Giménez‐Llort, L., Pèzzola, A., Reggio, R., Martı́nez, E., Fuxé, K., & Ferré, S. (1996) · Neuroscience Letters · doi:10.1016/s0304-3940(96)13143-8 · Cited by 74
Melatonin and Depression: A Translational Perspective From Animal Models to Clinical Studies
Tonon, A. C., Pilz, L. K., Markus, R. P., Hidalgo, M. P. L., & Elisabetsky, E. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.638981 · Cited by 79
Muscarinic Acetylcholine Receptor Knockout Mice
Wess, J., Zhang, W., Duttaroy, A., Miyakawa, T., Gomeza, J., Cui, Y., Basile, A. S., Bymaster, F. P., McKinzie, D. L., Felder, C. C., et al. (2004) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-18934-0_3 · Cited by 73
Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice
Schmidt, L. S., Thomsen, M., Weikop, P., Dencker, D., Wess, J., Woldbye, D. P. D., Wörtwein, G., & Fink‐Jensen, A. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2225-4 · Cited by 74
Scopolamine augments C-fos and zif/268 messenger rna expression induced by the full D1 dopamine receptor agonist SKF-82958 in the intact rat striatum
Wang, J. Q., & McGinty, J. F. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00597-8 · Cited by 73
Changes to interneuron-driven striatal microcircuits in a rat model of Parkinson's disease
Salin, P., López, I. P., Kachidian, P., Barroso‐Chinea, P., Rico, A. J., Gómez-Bautista, V., Coulon, P., Goff, L. K., & Lanciego, J. L. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.03.006 · Cited by 72
The Full D1 Dopamine Receptor Agonist SKF-82958 Induces Neuropeptide mRNA in the Normosensitive Striatum of Rats: Regulation of D1/D2 Interactions by Muscarinic Receptors
Wang, J. Q., & McGinty, J. F. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36678-9 · Cited by 72
Expression of D3 receptor messenger RNA and binding sites in monkey striatum and substantia nigra after nigrostriatal degeneration: effect of levodopa treatment
Quik, M., Police, S. M. C., He, L., Monte, D. A. D., & Langston, J. W. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00130-5 · Cited by 72
Novel Strains of Mice Deficient for the Vesicular Acetylcholine Transporter: Insights on Transcriptional Regulation and Control of Locomotor Behavior
Martins-Silva, C., Jaeger, X. D., Guzmán, M. S., Lima, R. D. F., Santos, M., Kushmerick, C., Gomez, M. V., Caron, M. G., Prado, M. A. M., & Prado, V. F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017611 · Cited by 71
Reaction Time Responding in Rats
Blokland, A. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(98)00013-x · Cited by 70
Identification of an ATP‐sensitive potassium channel current in rat striatal cholinergic interneurones
Lee, K., Dixon, A. K., Freeman, T. C., & Richardson, P. J. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.441bk.x · Cited by 70
Inhibition by adenosine A2A receptors of NMDA but not AMPA currents in rat neostriatal neurons
Wirkner, K., Aßmann, H., Köles, L., Gerevich, Z., Franke, H., Nörenberg, W., Boehm, R., & Illés, P. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703234 · Cited by 69
Antiparkinsonian actions of glutamate antagonists — alone and with L-DOPA: A review of evidence and suggestions for possible mechanisms
Starr, M. S. (1995) · Journal of Neural Transmission - Parkinsons Disease and Dementia Section · doi:10.1007/bf02251229 · Cited by 69
Developmental exposure to pesticides zineb and/or endosulfan renders the nigrostriatal dopamine system more susceptible to these environmental chemicals later in life
Jia, Z., & Misra, H. P. (2007) · NeuroToxicology · doi:10.1016/j.neuro.2007.04.003 · Cited by 68
Dopaminergic Lateralisation in the Forebrain: Relations to Behavioural Asymmetries and Anxiety in Male Wistar Rats
Thiel, C. M., & Schwarting, R. K. W. (2001) · Neuropsychobiology · doi:10.1159/000054889 · Cited by 68
Pharmacological animal models of Tourette syndrome
Bronfeld, M., Israelashvili, M., & Bar‐Gad, I. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.09.010 · Cited by 70
The cholinergic system and neostriatal memory functions
Havekes, R., Abel, T. G., & van der Zee, E. A. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.11.047 · Cited by 69
Dopamine D1-Like and D2-Like Receptors in the Dorsal Striatum Control Different Aspects of Attentional Performance in the Five-Choice Serial Reaction Time Task Under a Condition of Increased Activity of Corticostriatal Inputs
Agnoli, L., Mainolfi, P., Invernizzi, R. W., & Carli, M. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.236 · Cited by 70
Dopaminergic Regulation of Striatal Interneurons in Reward and Addiction: Focus on Alcohol
Clarke, R. B. C., & Adermark, L. (2015) · Neural Plasticity · doi:10.1155/2015/814567 · Cited by 68
Role of Cdk5 in Drug Abuse and Plasticity
Benavides, D. R., & Bibb, J. A. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1316.041 · Cited by 64
Role of vesicular dopamine in the in vivo stimulation of striatal dopamine transmission by amphetamine: Evidence from microdialysis and Fos immunohistochemistry
Cadoni, C., Pinna, A., Russi, G., Consolo, S., & Chiara, G. D. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00507-2 · Cited by 64
Self-citation
Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse, and Parkinson’s Disease
Dencker, D., Thomsen, M., Wörtwein, G., Weikop, P., Cui, Y., Jeon, J., Wess, J., & Fink‐Jensen, A. (2011) · ACS Chemical Neuroscience · doi:10.1021/cn200110q · Cited by 63
Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants.
Sakae, N., Yamasaki, N., Kitaichi, K., Fukuda, T., Yamada, M., Yoshikawa, H., Hiranita, T., Tatsumi, Y., Kira, J., Yamamoto, T., et al. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn215 · Cited by 64
Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat—II. Evidence for striataln-methyl-d-aspartate receptor regulation of striatonigral gabaergic transmission and motor function
Morari, M., O'Connor, W. T., Ungerstedt, U., Bianchi, C. L., & Fuxé, K. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00556-0 · Cited by 63
Acetylcholine/dopamine interaction in planaria
Buttarelli, F. R., Pontieri, F. E., Margotta, V., & Palladini, G. (2000) · Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology · doi:10.1016/s0742-8413(99)00111-5 · Cited by 62
M4 muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition
Koshimizu, H., Leiter, L. M., & Miyakawa, T. (2012) · Molecular Brain · doi:10.1186/1756-6606-5-10 · Cited by 61
Striatal dopamine–NMDA receptor interactions in the modulation of glutamate release in the substantia nigra pars reticulata in vivo: opposite role for D1 and D2 receptors
Marti, M., Mela, F., Bianchi, C., Beani, L., & Morari, M. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01169.x · Cited by 62
Piribedil Enhances Frontocortical and Hippocampal Release of Acetylcholine in Freely Moving Rats by Blockade of α2A-Adrenoceptors: A Dialysis Comparison to Talipexole and Quinelorane in the Absence of Acetylcholinesterase Inhibitors
Gobert, A., Cara, B. D., Cistarelli, L., & Millan, M. J. (2003) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.102.046383 · Cited by 60
Role of the parafascicular thalamic nucleus and N-methyl-d-aspartate transmission in the D1-dependent control of in vivo acetylcholine release in rat striatum
Consolo, S., Baronio, P., Guidi, G., & Chiara, G. D. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00421-1 · Cited by 59
Self-citation
The involvement of dopamine in the striatum in passive avoidance training in the chick
Stewart, M. G., Kabai, P., Harrison, E., Steele, R. J., Kossut, M. M., Gierdalski, M., & Csillag, A. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00345-j · Cited by 59
Effect of neostigmine on concentration and extraction fraction of acetylcholine using quantitative microdialysis
Vinson, P. N., & Justice, J. B. (1997) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(96)02213-3 · Cited by 58
Quantitative autoradiography reveals regionally selective changes in dopamine D1 and D2 receptor binding in the genetically dystonic hamster
Nóbrega, J. N., Richter, A., Tozman, N., Jiwa, D., & Löscher, W. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00511-0 · Cited by 58
The effects of D1 or D2 dopamine receptor blockade on zif/268 and preprodynorphin gene expression in rat forebrain following a short-term cocaine binge
Daunais, J. B., & McGinty, J. F. (1996) · Molecular Brain Research · doi:10.1016/0169-328x(95)00226-i · Cited by 59
Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS)
Veeraragavan, S., Graham, D. F., Bui, N., Yuva‐Paylor, L. A., Wess, J., & Paylor, R. E. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.11.018 · Cited by 63
Nicotine Alters Striatal Glutamate Function and Decreases the Apomorphine-Induced Contralateral Rotations in 6-OHDA-Lesioned Rats
Meshul, C. K., Kamel, D., Moore, C., Kay, T. S., & Krentz, L. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.7900 · Cited by 57
Promoter Region of the Rat m4 Muscarinic Acetylcholine Receptor Gene Contains a Cell Type-specific Silencer Element
Mieda, M., Haga, T., & Saffen, D. W. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.9.5177 · Cited by 57
An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine
Dencker, D., Weikop, P., Sørensen, G., Woldbye, D. P. D., Wörtwein, G., Wess, J., & Fink‐Jensen, A. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2751-8 · Cited by 56
Correlating Physiology with Gene Expression in Striatal Cholinergic Neurones
Richardson, P. J., Dixon, A. K., Lee, K. C., Bell, M. I., Cox, P. J., Williams, R. E., Pinnock, R. D., & Freeman, T. C. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.740839.x · Cited by 56
Antipsychotic-Induced Rabbit Syndrome
Schwartz, M., & Hocherman, S. (2004) · CNS Drugs · doi:10.2165/00023210-200418040-00002 · Cited by 55
Micturition-related electrophysiological properties in the substantia nigra pars compacta and the ventral tegmental area in cats
Sakakibara, R., Nakazawa, K., Uchiyama, T., Yoshiyama, M., Yamanishi, T., & Hattori, T. (2002) · Autonomic Neuroscience · doi:10.1016/s1566-0702(02)00180-7 · Cited by 55
Synergistically Interacting Dopamine D1 and NMDA Receptors Mediate Nonvesicular Transporter-Dependent GABA Release from Rat Striatal Medium Spiny Neurons
Schoffelmeer, A. N. M., Vanderschuren, L. J. M. J., Vries, T. J. D., Hogenboom, F., Wardeh, G., & Mulder, A. H. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-09-03496.2000 · Cited by 55
Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments
Cai, Y., Nielsen, B. E., Boxer, E. E., Aoto, J. N., & Ford, C. (2021) · Neuron · doi:10.1016/j.neuron.2021.01.028 · Cited by 55
Functional and molecular characterization of metabotropic glutamate receptors expressed in rat striatal cholinergic interneurones
Bell, M. I., Richardson, P. J., & Lee, K. C. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00815.x · Cited by 54
Potential role of muscarinic receptors in schizophrenia
Bymaster, F. P., Shannon, H. E., Rasmussen, K., DeLapp, N. W., Ward, J. S., Calligaro, D. O., Mitch, C. H., Whitesitt, C. A., Ludvigsen, T. S., Sheardown, M. J., et al. (1999) · Life Sciences · doi:10.1016/s0024-3205(98)00597-9 · Cited by 54
Effects of Activation of NMDA and AMPA Glutamate Receptors on the Extracellular Concentrations of Dopamine, Acetylcholine, and GABA in Striatum of the Awake Rat: A Microdialysis Study
Hernández, L. F., Segovia, G., & Mora, F. (2003) · Neurochemical Research · doi:10.1023/a:1026115607216 · Cited by 54
Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre‐synaptic muscarinic receptor activation from rat striatal synaptosomes
Martire, M., D’Amico, M., Panza, E., Miceli, F., Viggiano, D., Lavergata, F., Iannotti, F. A., Barrese, V., Preziosi, P., Annunziato, L., et al. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04562.x · Cited by 53
Regulation of Neurotransmitter Interactions in the Ventral Striatum
McGinty, J. F. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09265.x · Cited by 53
Cortical stimulation induces Fos expression in striatal neurons via NMDA glutamate and dopamine receptors
Liste, I., Rozas, G., Guerra, M. J., & Labandeira-García, J. L. (1995) · Brain Research · doi:10.1016/0006-8993(95)00958-s · Cited by 53
The muscarinic agonist xanomeline increases monoamine release and immediate early gene expression in the rat prefrontal cortex
Perry, K. W., Nisenbaum, L. K., George, C. A., Shannon, H. E., Felder, C. C., & Bymaster, F. P. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01017-9 · Cited by 52
Intrastriatal injection of a muscarinic receptor agonist and antagonist regulates striatal neuropeptide mRNA expression in normal and amphetamine-treated rats
Wang, J. Q., & McGinty, J. F. (1997) · Brain Research · doi:10.1016/s0006-8993(96)01244-9 · Cited by 51
Oligodendrocyte-specific gene expression in mouse brain: Use of a myelin-forming cell type-specific promoter in an adeno-associated virus
Chen, H., McCarty, D. M., Bruce, A. T., Suzuki, K., & Suzuki, K. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990215)55:4 · Cited by 71
Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor
Fink‐Jensen, A., Schmidt, L. S., Dencker, D., Schülein, C., Wess, J., Wörtwein, G., & Woldbye, D. P. D. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.01.018 · Cited by 50
Distribution of AMPA receptor subunit mRNAs in the human basal ganglia: an in situ hybridization study
Tomiyama, M., Palacios, J. M., Cortés, R., Vilaró, M. T., & Mengod, G. (1997) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00022-3 · Cited by 50
Attenuation of Cocaine's Reinforcing and Discriminative Stimulus Effects via Muscarinic M1 Acetylcholine Receptor Stimulation
Thomsen, M., Conn, P. J., Lindsley, C. W., Wess, J., Boon, J. Y., Fulton, B. S., Fink‐Jensen, A., & Caine, S. B. (2009) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.109.162057 · Cited by 49
Brain reactivity to specific symptom provocation indicates prospective therapeutic outcome in OCD
Hendler, T. (2003) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(03)00091-x · Cited by 49
Kir2 potassium channels in rat striatum are strategically localized to control basal ganglia function
Prüß, H., Wenzel, M. E., Eulitz, D., Thomzig, A., Karschin, A., & Veh, R. W. (2003) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00649-6 · Cited by 49
Glutamate decarboxylase messenger RNA in rat pallidum: Comparison of the effects of haloperidol, clozapine and combined haloperidol-scopolamine treatments
Delfs, J. M., Anegawa, N. J., & Chesselet, M. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00572-m · Cited by 49
Protection against dopaminergic nigrostriatal cell death by excitatory input ablation
Takada, M., Matsumura, M., Kojima, J., Yamaji, Y., Inase, M., Tokuno, H., Nambu, A., & Imai, H. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00062.x · Cited by 49
Effects of l-DOPA-therapy on dopamine D2 receptor mRNA expression in the striatum of MPTP-intoxicated parkinsonian monkeys
Herrero, M. T., Augood, S. J., Asensi, H., Hirsch, É. C., Agid, Y., Obeso, J. A., & Emson, P. C. (1996) · Molecular Brain Research · doi:10.1016/s0169-328x(96)00157-x · Cited by 48
Modulation of prepulse inhibition through both M1 and M4 muscarinic receptors in mice
Thomsen, M., Wess, J., Fulton, B. S., Fink‐Jensen, A., & Caine, S. B. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1740-z · Cited by 48
Anatomy, physiology, and pharmacology of the basal ganglia
Pollack, A. E. (2001) · Neurologic Clinics · doi:10.1016/s0733-8619(05)70032-3 · Cited by 48
Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice
Kim, D. S., & Palmiter, R. D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.252753799 · Cited by 47
Pathophysiology and biochemistry of dyskinesia: clues for the development of non-dopaminergic treatments
Jenner, P. G. (2000) · Journal of Neurology · doi:10.1007/pl00007760 · Cited by 47
Effects of selective adenosine A1 and A2a agonists on amphetamine-induced locomotion and c-Fos in striatum and nucleus accumbens
Turgeon, S. M., Pollack, A. E., Schusheim, L., & Fink, J. S. (1996) · Brain Research · doi:10.1016/0006-8993(95)01223-0 · Cited by 47
Regulation of Ionotropic Glutamate Receptors in the Rat Brain in Response to the Atypical Antipsychotic Seroquel (Quetiapine Fumarate)
Tascedda, F. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00034-2 · Cited by 47
S32504, a Novel Naphtoxazine Agonist at Dopamine D3/D2 Receptors: II. Actions in Rodent, Primate, and Cellular Models of Antiparkinsonian Activity in Comparison to Ropinirole
Millan, M. J., Cara, B. D., Hill, M. P., Jackson, M., Joyce, J. N., Brotchie, J. M., McGuire, S., Crossman, A. R., Smith, L. A., Jenner, P. G., et al. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.062414 · Cited by 47
Unrestricted free-choice ethanol self-administration in rats causes long-term neuroadaptations in the nucleus accumbens and caudate putamen
Nestby, P., Vanderschuren, L. J. M. J., Vries, T. J. D., Mulder, A. H., Wardeh, G., Hogenboom, F., & Schoffelmeer, A. N. M. (1999) · Psychopharmacology · doi:10.1007/s002130050838 · Cited by 46
Social isolation and social interaction alter regional brain opioid receptor binding in rats
Vanderschuren, L. J. M. J., Stein, E. A., Wiegant, V. M., & van Ree, J. M. (1995) · European Neuropsychopharmacology · doi:10.1016/0924-977x(95)00010-m · Cited by 48
Augmentation of locomotor activity by chronic phencyclidine is associated with an increase in striatal NMDA receptor function and an upregulation of the NR1 receptor subunit
Hanania, T., Hillman, G. R., & Johnson, K. M. (1999) · Synapse · doi:10.1002/(sici)1098-2396(19990301)31:3 · Cited by 46
Neurobiological issues in Tourette syndrome
Singer, H. S. (1994) · Brain and Development · doi:10.1016/0387-7604(94)90122-8 · Cited by 46
Different sensitivity of in vivo acetylcholine transmission to D1 receptor stimulation in shell and core of nucleus accumbens
Consolo, S., Caltavuturo, C., Colli, E., Recchia, M., & Chiara, G. D. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00309-1 · Cited by 44
Self-citation
Evidence for striatal dopaminergic overactivity in paroxysmal dystonia indicated by microinjections in a genetic rodent model
Rehders, J. H., Löscher, W., & Richter, A. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00073-7 · Cited by 44
NR2A and NR2B subunit containing NMDA receptors differentially regulate striatal output pathways
Fantin, M., Marti, M., Auberson, Y. P., & Morari, M. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04966.x · Cited by 42

Authors: Di Chiara, G., Morelli, M., & Consolo, S.
Affiliations: University of Cagliari (IT)
Mario Negri Institute for Pharmacological Research (IT)
ORCID: Morelli, Micaela
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 1994-06
Volume: 17
Issue: 6
Pages: 228-233
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/0166-2236(94)90005-1
OpenAlex: W1990162104
Semantic Scholar: 6620d60a424c6c77bf86292e9bd8b24706c6c57f
Cited by: 467
References: 72
Citations by year: 2026: 2 · 2025: 2 · 2024: 5 · 2023: 1 · 2022: 4 · 2021: 6 · 2020: 8 · 2019: 4 · 2018: 8 · 2017: 11 · 2016: 9 · 2015: 6 · 2014: 7 · 2013: 6 · 2012: 13
FWCI: 4.49
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Keywords: striatum, acetylcholine, dopamine, NMDA receptor, cholinergic interneurons, medium spiny neurons, basal ganglia, neurotransmitter interactions, basal ganglia disorders, neuromodulation
MeSH terms: Acetylcholine, Animals, Corpus Striatum, Dopamine, Humans, Synaptic Transmission, Receptors, Dopamine, N-Methylaspartate, Neurotransmitter Agents

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Modulatory functions of neurotransmitters in the striatum: ACh/dopamine/NMDA interactions

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks