The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes
Open accessAbstract
T-cell activation in the absence of co-stimulatory signals can lead to induction of anergy. Professional antigen-presenting cells (APCs) of bone marrow origin, such as macrophages and dendritic cells, can provide co-stimulation through molecules such as B7-1 and B7-2. In addition, cells of epithelial origin can function as 'non-professional' APCs when activated. In these circumstances, the functional consequences of the T cell-APC interaction may differ, perhaps due to the nature of the co-stimulatory pathways utilized and/or the cytokines encountered by the T cell. Here, Brian Nickoloff and Laurence Turka suggest that these differences may be important in regulating immune responses to local antigens and also in maintaining self-tolerance.
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Cites
CTLA-4 is a second receptor for the B cell activation antigen B7.
Linsley, P. S., Brady, W., Urnes, M., Grosmaire, L. S., Damle, N. K., & Ledbetter, J. A. (1991) · The Journal of experimental medicine · doi:10.1084/jem.174.3.561 · Cited by 1,685
Schwartz, R. H. (1992) · Cell · doi:10.1016/s0092-8674(05)80055-8 · Cited by 1,293
Cited by
Aloisi, F., Ria, F., Penna, G., & Adorini, L. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.10.4671 · Cited by 276
Organization of the skin immune system and compartmentalized immune responses in infectious diseases
Quaresma, J. A. S. (2019) · Clinical Microbiology Reviews · doi:10.1128/cmr.00034-18 · Cited by 149
Clayton, K., Vallejo, A., Sirvent, S., Davies, J., Porter, G., Reading, I. C., Lim, F., Ardern‐Jones, M. R., & Polak, M. E. (2021) · British Journal of Dermatology · doi:10.1111/bjd.19431 · Cited by 28
Falanga, V., & Faria, K. (2007) · Principles of Tissue Engineering · doi:10.1016/b978-012370615-7/50081-0 · Cited by 13
Metadata
- Authors
- Nickoloff, B. J., & Turka, L. A.
- Venue
- Immunology Today
- Publisher
- Elsevier BV
- Published
- 1994-10
- Volume
- 15
- Issue
- 10
- Pages
- 464-469
- ISSN
- 0167-5699 (ISSN-L)
- OpenAlex
- W2063638849
- Cited by
- 240
- References
- 2
- FWCI
- 8.75
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes. https://app.cochat.ai/papers/10.1016/0167-5699(94)90190-2
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- Nickoloff, B. J., & Turka, L. A. (1994). Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes. Immunology Today. https://doi.org/10.1016/0167-5699(94)90190-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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