The Vaccine Adverse Event Reporting System (VAERS)
Abstract
Immunizations against most vaccine-preventable diseases will be needed indefinitely unless the disease is eradicated. Public acceptance of immunizations may be threatened as vaccine coverage increases and disease decreases, however, due to the increase in both causally and coincidentally related vaccine adverse events. The post-marketing surveillance for such events in the USA in response to the mandatory reporting requirements of the National Childhood Injury Act of 1986. While VAERS has many methodological limitations intrinsic to such systems, it can play an important role in helping to monitor vaccine safety and maintain public confidence in immunizations.
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Healthcare providers, vaccine manufacturers, and the public can submit reports to VAERS.
“Healthcare providers, vaccine manufacturers, and the public can submit reports to the system.6”
From A comprehensive analysis of the efficacy and safety of COVID-19 vaccines (2021) · cites this paper as [6]
VAERS is comanaged by the CDC and the FDA and has been used to detect possible safety problems in U.S.-licensed vaccines since 1990.
“The VAERS is comanaged by the CDC and the FDA and has been used to detect possible safety problems in U.S.-licensed vaccines since 1990.”
From A comprehensive analysis of the efficacy and safety of COVID-19 vaccines (2021) · cites this paper as [6]
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- Authors
- CHEN, R., RASTOGI, S., MULLEN, J., HAYES, S., COCHI, S., DONLON, J., & WASSILAK, S.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Center for Biologics Evaluation and Research (US)
- Corresponding author
- CHEN, R
- ORCID
- CHEN, R
- Venue
- Vaccine
- Publisher
- Elsevier BV
- Published
- 1994-05
- Volume
- 12
- Issue
- 6
- Pages
- 542-550
- ISSN
- 0264-410X (ISSN-L)
- OpenAlex
- W2001219627
- Cited by
- 498
- References
- 44
- Citations by year
- 2026: 11 · 2025: 20 · 2024: 15 · 2023: 26 · 2022: 41 · 2021: 45 · 2020: 14 · 2019: 8 · 2018: 14 · 2017: 13 · 2016: 15 · 2015: 21 · 2014: 13 · 2013: 24 · 2012: 11
- FWCI
- 9.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Vaccine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Health Sciences › Medicine › Epidemiology › Data-Driven Disease Surveillance
- Social Sciences › Health › Vaccine Coverage and Hesitancy
- Keywords
- VAERS, vaccine adverse events, post-marketing surveillance, vaccine safety, mandatory reporting, vaccine-preventable diseases, causality assessment
- MeSH terms
- Humans, Vaccines, Adverse Drug Reaction Reporting Systems
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