Cited by 498Pharmacovigilance and Adverse Drug ReactionsData-Driven Disease SurveillanceVaccine Coverage and Hesitancy

The Vaccine Adverse Event Reporting System (VAERS)

CHEN, R, RASTOGI, S, MULLEN, J, HAYES, S, COCHI, S, DONLON, J, WASSILAK, S·1994·Vaccine

Abstract

Immunizations against most vaccine-preventable diseases will be needed indefinitely unless the disease is eradicated. Public acceptance of immunizations may be threatened as vaccine coverage increases and disease decreases, however, due to the increase in both causally and coincidentally related vaccine adverse events. The post-marketing surveillance for such events in the USA in response to the mandatory reporting requirements of the National Childhood Injury Act of 1986. While VAERS has many methodological limitations intrinsic to such systems, it can play an important role in helping to monitor vaccine safety and maintain public confidence in immunizations.

Integrity signals

Registry

Crossref · 10.1016/0264-410x(94)90315-8

Cites

44 of 44 references verified0 citation errors · 0 not checkable

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Authors
CHEN, R., RASTOGI, S., MULLEN, J., HAYES, S., COCHI, S., DONLON, J., & WASSILAK, S.
Affiliations
  • Centers for Disease Control and Prevention (US)
  • Center for Biologics Evaluation and Research (US)
Corresponding author
CHEN, R
ORCID
CHEN, R
Venue
Vaccine
Publisher
Elsevier BV
Published
1994-05
Volume
12
Issue
6
Pages
542-550
ISSN
0264-410X (ISSN-L)
OpenAlex
W2001219627
Cited by
498
References
44
Citations by year
2026: 11 · 2025: 20 · 2024: 15 · 2023: 26 · 2022: 41 · 2021: 45 · 2020: 14 · 2019: 8 · 2018: 14 · 2017: 13 · 2016: 15 · 2015: 21 · 2014: 13 · 2013: 24 · 2012: 11
FWCI
9.95
Type
journal article
Language
en
Open access
closed
Locations
  • Vaccine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
  • Health Sciences › Medicine › Epidemiology › Data-Driven Disease Surveillance
  • Social Sciences › Health › Vaccine Coverage and Hesitancy
Keywords
VAERS, vaccine adverse events, post-marketing surveillance, vaccine safety, mandatory reporting, vaccine-preventable diseases, causality assessment
MeSH terms
Humans, Vaccines, Adverse Drug Reaction Reporting Systems

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