Molecular Epidemiology of Polioviruses
Abstract
Poliovirus isolates can be identified according to their genotypes with use of the technique of oligonucleotide fingerprinting. Fingerprint analysis is performed by cleaving the viral RNA genome with ribonuclease T1 and separating the fragments (oligonucleotides) in two dimensions. The larger, structurally unique oligonucleotides distribute into patterns ("fingerprints") highly characteristic of a specific overall RNA sequence. Isolates from the same epidemic have very similar fingerprints. Isolates from distinct epidemics have very different fingerprints, a consequence of the rapid evolution of polioviruses during replication in humans. Similarity in the fingerprints of case isolates provides independent evidence for epidemiologic linkage. Fingerprinting can readily distinguish vaccine-related isolates from wild strains. Contemporary vaccine-related isolates are very probably vaccine-derived because their fingerprints contain characteristic vaccine-strain oligonucleotide spots (types 1 and 3) and because their wild-type parents are unlikely to have survived largely unaltered in the natural environment. Some examples of applications of this technique within different epidemiologic settings are described.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Conclusive evidence for the vaccine origin of the Poland outbreak came from retrospective oligonucleotide fingerprinting and nucleotide sequencing studies of outbreak isolates.
“conclusive evidence for the vaccine origin of the outbreak came from retrospective oligonucleotide fingerprinting (86) and nucleotide sequencing (118) studies of outbreak isolates.”
From VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION (2005) · cites this paper as [86]
Cites
Molecular variation of type 1 vaccine-related and wild polioviruses during replication in humans
Nottay, B. K., Kew, O. M., Hatch, M. H., Heyward, J. T., & Obijeski, J. F. (1981) · Virology · doi:10.1016/0042-6822(81)90448-7 · Cited by 190 · see citing works
Self-citationChronic progressive poliomyelitis secondary to vaccination of an immunodeficient child
Davis, L. E., Bodian, D., Price, D., Butler, I. J., & Vickers, J. H. (1977) · New England Journal of Medicine · doi:10.1056/nejm197708042970503 · Cited by 155 · see citing works
Multiple Genetic Changes Can Occur in the Oral Poliovaccines upon Replication in Humans
Kew, O. M., Nottay, B. K., Hatch, M. H., Nakano, J. H., & Obijeski, J. F. (1981) · Journal of General Virology · doi:10.1099/0022-1317-56-2-337 · Cited by 149 · see citing works
Self-citationOligonucleotide mapping: evaluation of its sensitivity by computer-simulation
Aaronson, R. P., Young, J. F., & Palese, P. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.1.237 · Cited by 71 · see citing works
Minor, P. D., Schild, G. C., Ferguson, M. A. J., MacKay, A., Magrath, D. I., John, A., Yates, P. J., & Spitz, M. (1982) · Journal of General Virology · doi:10.1099/0022-1317-61-2-167 · Cited by 58 · see citing works
Yoneyama, T., Hagiwara, A., Hara, M., & Shimojo, H. (1982) · Infection and Immunity · doi:10.1128/iai.37.1.46-53.1982 · Cited by 45 · see citing works
Nomoto, A., Kitamura, N., Lee, J. J., et al. (1981) · Virology · doi:10.1016/0042-6822(81)90627-9 · Cited by 29 · see citing works
Oligonucleotide fingerprinting of viral genomes.
Clewley, J. P., & Dh, B. (1982) · PubMed · Cited by 12 · see citing works
The epidemic of type 3 poliomyelitis in Poland in 1968.
Kostrzewski, J., Kulesza, A., & Abgarowicz, A. (1970) · Przeglad Epidemiologiczny · Cited by 10 · see citing works
Mass immunization cases: drug manufacturers' liability for failure to warn.
Mann, M. E. (1976) · PubMed · Cited by 4 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION
Kew, O. M., Sutter, R. W., de Gourville, E. M., Dowdle, W. R., & Pallansch, M. A. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.58.030603.123625 · Cited by 703 · see citing works
Self-citationThe Vaccine Adverse Event Reporting System (VAERS)
CHEN, R., RASTOGI, S., MULLEN, J., HAYES, S., COCHI, S., DONLON, J., & WASSILAK, S. (1994) · Vaccine · doi:10.1016/0264-410x(94)90315-8 · Cited by 498 · see citing works
Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence
Yeh, M. T., Bujaki, E., Dolan, P. T., Smith, M., Wahid, R., Konz, J., Weiner, A. J., Bandyopadhyay, A. S., Van Damme, P., De Coster, I., et al. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.04.003 · Cited by 221 · see citing works
Prolonged replication of a type 1 vaccine-derived poliovirus in an immunodeficient patient
Kew, O. M., Sutter, R. W., Nottay, B. K., McDonough, M. J., Prevots, D. R., Quick, L., & Pallansch, M. A. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.10.2893-2899.1998 · Cited by 213 · see citing works
Self-citationNatural genetic recombination between co-circulating heterotypic enteroviruses
Oprisan, G., Combiescu, M., Guillot, S., Caro, V., Combiescu, A., Delpeyroux, F., & Crainic, R. (2002) · Journal of General Virology · doi:10.1099/0022-1317-83-9-2193 · Cited by 105 · see citing works
Lipskaya, G. Y., Chervonskaya, E. A., Belova, G. I., Maslova, S. V., Kutateladze, T. N., Drozdov, S. G., Mulders, M., Pallansch, M. A., Kew, O. M., & Agol, V. I. (1995) · Journal of General Virology · doi:10.1099/0022-1317-76-7-1687 · Cited by 34 · see citing works
Self-citationKorotkova, E., Laassri, M., Zagorodnyaya, T., Petrovskaya, S., Rodionova, E., Cherkasova, E., Gmyl, A., Ivanova, O., Eremeeva, T., Lipskaya, G., et al. (2017) · Viruses · doi:10.3390/v9110353 · Cited by 23 · see citing works
- Authors
- Kew, O. M., & Nottay, B. K.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Corresponding author
- Kew, Olen M.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1984-05-01
- Volume
- 6
- Issue
- Supplement_2
- Pages
- S499-S504
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2148141318
- Cited by
- 51
- References
- 10
- Citations by year
- 2023: 1 · 2021: 1 · 2020: 1 · 2017: 2 · 2016: 1 · 2015: 3 · 2014: 5 · 2013: 1 · 2012: 2
- FWCI
- 1.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Health Sciences › Medicine › Infectious Diseases › Viral gastroenteritis research and epidemiology
- Keywords
- poliovirus, molecular epidemiology, oligonucleotide fingerprinting, ribonuclease T1, viral RNA genome, genotype identification, vaccine-derived poliovirus, wild-type poliovirus, poliovirus evolution
- MeSH terms
- Humans, Oligonucleotides, Poliomyelitis, Poliovirus Vaccine, Inactivated, Virus Replication, Poliovirus
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
