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Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

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Tau Phosphorylation Both In Vitro and in Cells

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A Phosphorylation‐Induced Turn Defines the Alzheimer’s Disease AT8 Antibody Epitope on the Tau Protein

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Pathological Assessment of Chronic Traumatic Encephalopathy

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MAIT cell deficiency exacerbates neuroinflammation in P301S human tau transgenic mice

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Early synaptic pathology is associated with small tau aggregates in Alzheimer’s disease

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Spatial transcriptomics in Alzheimer's disease: technologies, challenges and discoveries

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Targeted nanomedicine strategies for Alzheimer’s disease therapy

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G272V and P301L Mutations Induce Isoform Specific Tau Mislocalization to Dendritic Spines and Synaptic Dysfunctions in Cellular Models of 3R and 4R Tau Frontotemporal Dementia

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NEURONAL FUNCTIONS OF PROTEIN PHOSPHATASE 2A

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Evolving alterations of structural organization and functional connectivity in feedforward neural networks after induced P301L tau mutation

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Assessing Co‐Localization of ITM2B With Alzheimer's Disease and Limbic‐Predominant Age‐Related TDP ‐43 Encephalopathy Neuropathologic Changes

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Generation of 17q21.31 duplication iPSC-derived neurons as a model for primary tauopathies

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The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular modelPreprint

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τ Protein and the Neurofibrillary Pathology of Alzheimer’s Disease

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Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds

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Deep Trans-Omic Network Fusion for Molecular Mechanism of Alzheimer’s Disease

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Differentiating pathologic tau in chronic traumatic encephalopathy (CTE) from other tauopathies: A potential antibody panel assessment

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Examining the vulnerability of adult neuron subtypes to tau-mediated toxicity in Drosophila

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A novel pThr217 tau monoclonal antibody reveals neuropathological heterogeneity in tauopathies

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Morphological and Hyperphosphorylation Transitions of Nanoscale Tau Aggregates in Alzheimer's Disease

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Deep Learning-Based Classification of Temporal Stages of AT8-Labeled Tau Pathology After Experimental Traumatic Brain Injury

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Spatially pathogenic forms of tau detected in Alzheimer's disease brain tissue by fluorescence lifetime-based Förster resonance energy transfer

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Flow cytometry-based method to analyze the change in Tau phosphorylation in a hGSK-3β and hTau over-expressing EcR-293 cell line

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Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites

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Immunofluorescence: Dyes and Other Haptens Conjugated with Antibodies

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Correlation between tau phosphorylation sites and tangle morphology in Alzheimer's disease

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Structures of AT8 and PHF1 Phospho-Mimetic Tau: Insights Into the Posttranslational Modification Code of Tau Amyloid FormationPreprint

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Phospho-Tau Signature During Mitosis: AT8, p-T217 and p-S422 as Key Phospho-Epitopes

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Amyloid neuropathy, tauopathy, decreased cholinergic and dopaminergic neurons, long-term memory and motor deficits, and sleep disturbance in motopsin deficient mice

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Impact of Lysine Acetylation Mutations on the Structure of Full-Length Tau Fibrils

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Circadian timing and entrainment properties of the SCN pacemaker in the PS19 mouse model of tau pathology

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Progesterone induction of tau phosphorylation during the differentiation of human embryonic stem cells into neuroectodermal rosettes

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Fourier transform infrared spectroscopy detects distinct TAR DNA-binding protein 43 signatures in frontotemporal lobar degeneration

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Prefoldin 5 is a microtubule-associated protein that suppresses Tau aggregation and neurotoxicity

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Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer’s disease

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A compound enhancing lysosomal function reduces tau pathology, microglial reactivity and rescues working memory in 3xTg AD mice

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GV1001 reduces pathological 4R tau and functional deficits in models relevant to progressive supranuclear palsy

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Altering PTPRD via genetics or pharmacology modulates 3xTg-AD mouse neurofibrillary pathology

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Engineered Alzheimer Organoids Validate the Link Between Intracellular and Soluble p-Tau Biomarkers and Highlight the Contribution of Astrocytic Tau

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Up-regulation of tau, a brain microtubule- associated protein, in lens cortical fractions of aged αA-, αB-, and αA/B-crystallin knockout mice

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Parvalbumin interneurons in the hippocampal formation of individuals with Alzheimer’s disease: a neuropathological study of abnormal phosphorylated tau in neurons

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Perisomatic Granules of Hippocampal CA1 Neurons in Alzheimer’s Disease, Pre-Alzheimer Stage and Pick’s Disease: An Overlooked Pathological Entity

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Neuropathology and Genetics of Prion Protein and British Cerebral Amyloid Angiopathies

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Concomitant AD and DLB pathologies shape subfield microglia responses in the hippocampusPreprint

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Early and selective subcortical Tau pathology within the human Papez circuitPreprint

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Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and restoring cognitive deficits in the rTg4510 mouse model of tauopathyPreprint

Hulse, J. P., Maphis, N. M., Peabody, J., Chackerian, B., & Bhaskar, K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.05.588338 · Cited by 1

Super-Resolution Imaging Uncovers Nanoscale Tau Aggregate Hyperphosphorylation Patterns in Human Alzheimer’s Disease Brain TissuePreprint

Santiago-Ruiz, A. N., Hugelier, S., Bond, C. R., Lee, E. B., & Lakadamyali, M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.24.590893 · Cited by 1

Aberrant medial entorhinal cortex dynamics link tau pathology to spatial memory impairmentPreprint

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Structural and Synaptic Dysregulation Drives Network Vulnerability in APOE4 Human Neuronal NetworksPreprint

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Isogenic human stem cell models reveal mutation-dependent protective mechanisms of APOE3 Christchurch

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Tau Phosphorylation and Dephosphorylation in the Pathogenesis of Alzheimer’s Disease

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Animal Models of Tauopathy

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Development of a Lab-on-a-Chip Microfluidic System for the Detection of C-Reactive Protein in Whole Human Blood and an Antibody Biomarker for the Detection of Alzheimer's Disease

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Identification de déterminants génétiques impliqués dans la composante vasculaire de la MA, par analyses transcriptomiques, génétiques et moléculaires

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Validation of Animal Models of Dementia: Neurochemical Aspects

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Inhibition of Alzheimer’s type toxic aggregates of tau with fungal secondary metabolites

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Development and characterization of cell models of tau aggregation

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Investigating alterations in autophagy in Alzheimer’s disease using human brain tissue and skin-derived fibroblasts

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Single Molecule Imaging Reveals Tau Structure And Function On The Microtubule Surface

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Investigating the neuroprotective role of OGA inhibition by Thiamet-G against Alzheimer\'s disease

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The endolysosomal system in neuronal physiology and pathology

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Neurofibrillary Pathology in the Infundibular Nucleus in Relation to Age and Abnormal Hormone Levels

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Interstitial cells subjacent to the entorhinal region expressing somatostatin-28 immunoreactivity are susceptible to development of Alzheimer's disease-related cytoskeletal changes

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THE ROLE OF MICROTUBULE-ASSOCIATED PROTEIN TAU IN NEURONAL EXCITABILITY AND EPILEPTOGENESIS

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Tau Protein and the Neurofibrillary Pathology of Alzheimer’s Disease

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Characterization of microtubule associated protein tau isoforms and Alzheimer’s disease-like pathology in normal sheep (Ovis aries) - relevance to their potential as a model of Alzheimer’s disease.Preprint

Davies, E. S., Morphew, R. M., Cutress, D. J., Morton, A. J., & McBride, S. D. (2022) · Research Square · doi:10.21203/rs.3.rs-1419996/v1

Deep trans-omic network fusion reveals altered synaptic network in Alzheimer’s DiseasePreprint

Xie, L., Raj, Y., Varathan, P., He, B., Nho, K. T., Risacher, S. L., Salama, P., Saykin, A. J., & Yan, J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.02.490336

A single closed head injury in mice induces chronic, progressive white matter atrophy and increased phospho-tau expressing oligodendrocytesPreprint

Havlicek, D. F., Furhang, R., Nikulina, E., Smith-Salzberg, B., Lawless, S., Sevarin, S. A., Mallaboeva, S., Nayab, F., Seifert, A. C., Crary, J. F., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.19.492705

The β-amyloid oligomer Aβ*56 is associated with Alzheimer’s dementia independently of amyloid pathologyPreprint

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Differential Effects on In Vitro Tau Aggregation Due to 7, 11, and 14 Pseudophosphorylated Sites

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Neurons ensheathed by perineuronal nets are prone to hyperphosphorylation of tau protein in the hibernating Syrian hamster brain

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Early synaptic pathology is associated with small tau aggregates in Alzheimer’s diseasePreprint

Fertan, E., Kedia, S., Meisl, G., Cotton, M. W., Quaegebeur, A., Spillantini, M. G., & Klenerman, D. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.13.676039 · Cited by 1

P-TAU205 IS A BIOMARKER LINKED TO TAU-PET ABNORMALITY: A CROSS-SECTIONAL AND LONGITUDINAL STUDYPreprint

Lantero‐Rodriguez, J., Janelidze, S., Palmqvist, S., Braun-Wohlfahrt, L. S., Vávra, J., Bali, D., Dolado, A. O., Mattsson, N., Stomrud, E., Zetterberg, H., et al. (2025) · medRxiv · doi:10.1101/2025.10.21.25338437

Long-term locus coeruleus stimulation exacerbates tau pathology in PS19 mice

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Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicityPreprint

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Additional file 1 of The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation

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Additional file 2 of The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation

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Additional file 1 of Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau

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Additional file 1 of The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice

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Additional file 1 of Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue

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Tau Aggregation Modulators

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Correlation between in vivo 18 F‐flortaucipir PET and whole‐brain postmortem histological tau signals in Alzheimer's disease

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Tau reduction counteracts transcriptomic and behavioral abnormalities in an Alzheimer amyloid modelPreprint

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Human P301L tau expression in mice alters neuronal excitability independent of neurodegeneration

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