Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205
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Items 101–200 of 610
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- Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s diseaseSiddhartha Mondragón‐Rodríguez, Gustavo Basurto‐Islas, Ismael Santa‐María, Raúl Mena, Lester I. Binder, Jesús Ávila, Mark A. Smith, George L. Perry, Francisco García‐Sierra · 2008 · International Journal of Experimental Pathology
- p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositisNogalska, Anna, Terracciano, Chiara, D’Agostino, Carla, King Engel, W., Askanas, Valerie · 2009 · Acta Neuropathologica
- Hyperphosphorylated tau proteins differentiate corticobasal degeneration and Pick's diseaseValérie Buée‐Scherrer, Patrick R. Hof, Luc Buée, Béatrice Leveugle, Patrick Vermersch, Daniel P. Perl, C. Warren Olanow, André Delacourte · 1996 · Acta Neuropathologica
- JNK Plays a Key Role in Tau Hyperphosphorylation in Alzheimer's Disease ModelsPloia, Cristina, Antoniou, Xanthi, Sclip, Alessandra, Grande, Valentina, Cardinetti, Daniele, Colombo, Alessio, Canu, Nadia, Benussi, Luisa, Ghidoni, Roberta, Forloni, Gianluigi et al. · 2011 · Journal of Alzheimer's Disease
- The neuropathological profile of mild cognitive impairment (MCI): a systematic reviewBlossom C. M. Stephan, Sally Hunter, D Harris, David J. Llewellyn, Mario Siervo, Fiona E. Matthews, Carol Brayne · 2011 · Molecular Psychiatry
- Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer’s disease from a ferroptosis perspectivePaul J. Derry, Muralidhar L. Hegde, George R. Jackson, Rakez Kayed, James M. Tour, Ah-Lim Tsai, Thomas A. Kent · 2019 · Progress in Neurobiology
- Transient increases in intracellular calcium result in prolonged site-selective increases in tau phosphorylation through a glycogen synthase kinase 3β-dependent pathwayHartigan, Judith A., Johnson, Gail V.W. · 1999 · Journal of Biological Chemistry
- Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathiesStrang, Kevin H., Croft, Cara L., Sorrentino, Zachary A., Chakrabarty, Paramita, Golde, Todd E., Giasson, Benoit I. · 2018 · Journal of Biological Chemistry
- Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: potential significance for tau protein phosphorylationSheng, Jin G., Jones, Richard A., Zhou, Xue Q., McGinness, John M., Van Eldik, Linda J., Mrak, Robert E., Griffin, W.Sue T. · 2001 · Neurochemistry International
- Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesiaEmmanuel Planel, Alexis Bretteville, Li Liu, László Virág, Angela L. Du, Wai Haung Yu, Dennis W. Dickson, Robert A. Whittington, Karen Duff · 2009 · The FASEB Journal
- Palmitic and stearic fatty acids induce Alzheimer-like hyperphosphorylation of tau in primary rat cortical neuronsSachin P. Patil, Christina Chan · 2005 · Neuroscience Letters
- Comparison of the neurofibrillary pathology in Alzheimer’s disease and familial presenile dementia with tanglesSpillantini, M. G., Crowther, R. A., Goedert, M. · 1996 · Acta Neuropathologica
- Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic MiceChalermpalanupap, Termpanit, Schroeder, Jason P., Rorabaugh, Jacki M., Liles, L. Cameron, Lah, James J., Levey, Allan I., Weinshenker, David · 2018 · The Journal of Neuroscience
- Normal and Pathological Tau Proteins as Factors for Microtubule AssemblyAndré Delacourte, Luc Buée · 1997 · International review of cytology
- Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer’s diseaseRoberts, Malcolm, Sevastou, Ioanna, Imaizumi, Yoichi, Mistry, Kavita, Talma, Sonia, Dey, Madhurima, Gartlon, Jane, Ochiai, Hiroshi, Zhou, Zhi, Akasofu, Shigeru et al. · 2020 · Acta Neuropathologica Communications
- Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic miceLeroy, Karelle, Bretteville, Alexis, Schindowski, Katharina, Gilissen, Emmanuel, Authelet, Michèle, De Decker, Robert, Yilmaz, Zehra, Buée, Luc, Brion, Jean-Pierre · 2007 · The American Journal of Pathology
- E46K Human α-Synuclein Transgenic Mice Develop Lewy-like and Tau Pathology Associated with Age-dependent, Detrimental Motor ImpairmentKristel L. Emmer, Elisa A. Waxman, Jason P. Covy, Benoit I. Giasson · 2011 · Journal of Biological Chemistry
- Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transportKanaan, Nicholas M., Morfini, Gerardo, Pigino, Gustavo, LaPointe, Nichole E., Andreadis, Athena, Song, Yuyu, Leitman, Ellen, Binder, Lester I., Brady, Scott T. · 2012 · Neurobiology of Aging
- Retinal tau pathology in human glaucomasNeeru Gupta, Jessica Fong, Lee Cyn Ang, Yeni H. Yücel · 2008 · Canadian Journal of Ophthalmology
- The evolution of Alzheimer's disease‐related cytoskeletal pathology in the human raphe nucleiU. Rüb, Kelly Del Tredici, Christian Schultz, Dietmar Rudolf Thal, Eva Braak, Heiko Braak · 2000 · Neuropathology and Applied Neurobiology
- Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38δ at Thr50 promotes microtubule assemblyFeijoo, Carmen, Campbell, David G., Jakes, Ross, Goedert, Michel, Cuenda, Ana · 2005 · Journal of Cell Science
- Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylationCaroline Smet‐Nocca, Malgorzata Broncel, Jean‐Michel Wieruszeski, Caroline Tokarski, Xavier Hanoulle, Arnaud Leroy, Isabelle Landrieu, Christian H. Rolando, Guy M. Lippens, Christian P. R. Hackenberger · 2011 · Molecular BioSystems
- Propofol Directly Increases Tau PhosphorylationRobert A. Whittington, László Virág, François Marcouiller, Marie-Amélie Papon, Noura B. El Khoury, Carl Julien, Françoise Morin, Charles W. Emala, Emmanuel Planel · 2011 · PLoS ONE
- Pick's disease associated with the novel Tau gene mutation K369IManuela Neumann, Walter Schulz‐Schaeffer, R. Anthony Crowther, Michael J. Smith, Maria Grazia Spillantini, Michel Goedert, Hans A. Kretzschmar · 2001 · Annals of Neurology
- Cyclooxygenase‐1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's diseaseSangho Choi, Saba Aïd, Luca Caracciolo, Sakura Minami, Takako Niikura, Yasuji Matsuoka, Raymond Scott Turner, Mark P. Mattson, Francesca Bosetti · 2012 · Journal of Neurochemistry
- Aberrant Tau Phosphorylation by Glycogen Synthase Kinase-3β and JNK3 Induces Oligomeric Tau Fibrils in COS-7 CellsShinji Sato, Yoshitaka Tatebayashi, Takumi Akagi, De-Hua Chui, Miyuki Murayama, Tomohiro Miyasaka, Emmanuel Planel, Kentaro Tanemura, Xiaoyan Sun, Tsutomu Hashikawa et al. · 2002 · Journal of Biological Chemistry
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- Cortical microinfarcts and demyelination affect cognition in cases at high risk for dementiaKövari, E., Gold, G., Herrmann, F. R., Canuto, A., Hof, P. R., Bouras, C., Giannakopoulos, P. · 2007 · Neurology
- Alzheimer’s disease: Ablating single master site abolishes tau hyperphosphorylationStefanoska, Kristie, Gajwani, Mehul, Tan, Amanda R. P., Ahel, Holly I., Asih, Prita R., Volkerling, Alexander, Poljak, Anne, Ittner, Arne · 2022 · Science Advances
- NO synthase 2 ( NOS2 ) deletion promotes multiple pathologies in a mouse model of Alzheimer's diseaseColton, C. A., Vitek, M. P., Wink, D. A., Xu, Q., Cantillana, V., Previti, M. L., Van Nostrand, W. E., Weinberg, J. B., Dawson, H. · 2006 · Proceedings of the National Academy of Sciences
- Tau and α-Synuclein Pathology in Amygdala of Parkinsonism-Dementia Complex Patients of GuamMark S. Forman, Marie Luise Schmidt, Sanjay S. Kasturi, Daniel P. Perl, Virginia M.‐Y. Lee, John Q. Trojanowski · 2002 · American Journal Of Pathology
- Involvement of astroglial ceramide in palmitic acid‐induced Alzheimer‐like changes in primary neuronsSachin P. Patil, Joseph Melrose, Christina Chan · 2007 · European Journal of Neuroscience
- Dual modification of Alzheimer’s disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approachThomas, Stefani N., Funk, Kristen E., Wan, Yunhu, Liao, Zhongping, Davies, Peter, Kuret, Jeff, Yang, Austin J. · 2012 · Acta Neuropathologica
- Smoking exacerbates amyloid pathology in a mouse model of Alzheimer’s diseaseInés Moreno‐González, Lisbell D. Estrada, Elisabeth Sánchez‐Mejías, Claudio A. Soto · 2013 · Nature Communications
- Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's diseaseMasahiro Yanagisawa, Emmanuel Planel, Koichi Ishiguro, Shinobu C. Fujita · 1999 · FEBS Letters
- Analysis of Tau Phosphorylation and Truncation in a Mouse Model of Human TauopathyPatrice Delobel, Isabelle Lavenir, Graham Mathew Fraser, Esther Ingram, Max Holzer, Bernardino Francesco Ghetti, Maria Grazia Spillantini, R. Anthony Crowther, Michel Goedert · 2007 · American Journal Of Pathology
- Dishevelled Regulates the Metabolism of Amyloid Precursor Protein via Protein Kinase C/Mitogen-Activated Protein Kinase and c-Jun Terminal KinaseAmritpal K. Mudher, Susan C. Chapman, Jill C. Richardson, Ayodeji A. Asuni, Graham Gibb, Claire C. Pollard, Richard Killick, Tasfia Ahmed Iqbal, Frances Lucy Raymond, Ian M. Varndell et al. · 2001 · Journal of Neuroscience
- Analysis of gial acidic fibrillary protein in the human entorhinal cortex during aging and in Alzheimer's diseaseRaymonde Porchet, A. Probst, Constantin Bouras, Eduarda Dráberová, Pavel Dráber, Beat Michel Riederer · 2003 · PROTEOMICS
- Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic MiceIkeda, Masaki, Kawarai, Toshitaka, Kawarabayashi, Takeshi, Matsubara, Etsuro, Murakami, Tetsuro, Sasaki, Atsushi, Tomidokoro, Yasushi, Ikarashi, Yasushi, Kuribara, Hisashi, Ishiguro, Koichi et al. · 2005 · The American Journal of Pathology
- β-Amyloid deposition and tau phosphorylation in clinically characterized aged catsElizabeth Head, K. Moffat, Pritam Das, Floyd M. Sarsoza, Wayne W. Poon, Gary M Landsberg, Carl W. Cotman, M.P. Murphy · 2004 · Neurobiology of Aging
- Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stagesTharick Ali Pascoal, Andréa Lessa Benedet, Dana Tudorascu, Joseph Therriault, Sulantha Sanjeewa Mathotaarachchi, Mélissa Savard, Firoza Zubeida Lussier, Cécile Tissot, Mira Chamoun, Min Su Kang et al. · 2021 · Brain
- NMR Analysis of a Tau Phosphorylation PatternIsabelle Landrieu, Ludovic Lacosse, Arnaud Leroy, Jean‐Michel Wieruszeski, Xavier Trivelli, Alain Sillen, Nathalie Sibille, Harald Schwalbe, Krishna Saxena, Thomas Langer et al. · 2006 · Journal of the American Chemical Society
- A mutation affecting the sodium/proton exchanger, SLC9A6, causes mental retardation with tau depositionJames Y. Garbern, Manuela Neumann, John Q. Trojanowski, Virginia M.‐Y. Lee, Gerald L. Feldman, Joy W. Norris, Michael J. Friez, Charles E. Schwartz, Roger E. Stevenson, Anders A. F. Sima · 2010 · Brain
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- Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollutionLilian Calderón‐Garcidueñas, Andrea Herrera-Soto, Nur Jury, Barbara A. Maher, Angélica González-Maciel, Rafael Reynoso-Robles, Pablo Ruiz-Rudolph, Brigitte van Zundert, Lorena Varela‐Nallar · 2020 · Environmental Research
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- Regional conformational change involving phosphorylation of tau protein at the Thr231, precedes the structural change detected by Alz-50 antibody in Alzheimer's diseaseJosé Luna‐Muñoz, Francisco García‐Sierra, Viviana Falcón, Ivón Menéndez, Laura Chávez-Macías, Raúl Mena · 2005 · Journal of Alzheimer s Disease
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- A novel tau‐based rhesus monkey model of Alzheimer's pathogenesisDanielle Beckman, Paramita Chakrabarty, Sean P. Ott, Amanda Dao, Eric Zhou, William G.M. Janssen, Kristine Donis‐Cox, Scott Muller, Jeffrey H. Kordower, John H. Morrison · 2021 · Alzheimer s & Dementia
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- Protein Expression of Angiotensin-Converting Enzyme 2 (ACE2) is Upregulated in Brains with Alzheimer’s DiseaseQiyue Ding, Nataliia V. Shults, Sergiy G. Gychka, Brent T. Harris, Yuichiro Suzuki · 2021 · International Journal of Molecular Sciences
- Changes in the detergent‐insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progressionHales, Chadwick M., Dammer, Eric B., Deng, Qiudong, Duong, Duc M., Gearing, Marla, Troncoso, Juan C., Thambisetty, Madhav, Lah, James J., Shulman, Joshua M., Levey, Allan I. et al. · 2016 · PROTEOMICS
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- Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregationWoo Shik Shin, Jing Di, Qin Cao, Binsen Li, Paul M. Seidler, Kevin A. Murray, Gal Bitan, Lin Jiang · 2019 · Alzheimer s Research & Therapy
- Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing TherapiesPomeshchik, Yuriy, Klementieva, Oxana, Gil, Jeovanis, Martinsson, Isak, Hansen, Marita Grønning, de Vries, Tessa, Sancho-Balsells, Anna, Russ, Kaspar, Savchenko, Ekaterina, Collin, Anna et al. · 2020 · Stem Cell Reports
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- Phosphorylation of tau by glycogen synthase kinase 3β affects the ability of tau to promote microtubule self-assemblyMichelle A. Utton, André Vandecandelaere, Uta Wagner, C. Hugh Reynolds, Graham Gibb, Christopher C.J. Miller, Peter M. Bayley, Brian H. Anderton · 1997 · Biochemical Journal
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