The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Serotonin-containing neurons: their possible role in pain and analgesia
Abstract
Experimental evidence is reviewed showing that brain and spinal cord serotonergic neurons are involved in nociceptive responses, as well as in the analgesic effects of opiate narcotics. This evidence, based on studies employing pharmacological, surgical, electrophysiological, and dietary manipulations of central nervous system serotonergic neurotransmission, suggests that increases in the activity of brain and spinal cord serotonin neurons are associated with analgesia and enhanced antinociceptive drug potency, whereas decreases in the activities of these neurons correlate with hyperalgesia and diminished analgesic drug potency.
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Cites
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Cited by
Chronic pain in elderly people
Gagliese, L., & Melzack, R. (1997) · Pain · doi:10.1016/s0304-3959(96)03266-6 · Cited by 334
Organization of descending serotonergic projections to the spinal cord
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Mianserin and chronic pain: a double-blind placebo-controlled process and outcome study
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Metadata
- Authors
- Messing, R. B., & Lytle, L. D.
- Venue
- Pain
- Published
- 1977-10
- Volume
- 4
- Issue
- Supp C
- Pages
- 1-21
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W1977294562
- Cited by
- 398
- References
- 58
- FWCI
- 21.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Messing, R. B., & Lytle, L. D. (1977). Serotonin-containing neurons: their possible role in pain and analgesia. Pain. https://doi.org/10.1016/0304-3959(77)90083-5
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
