The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Echocardiographic assessment of patients with infectious endocarditis: Prediction of risk for complications
Open accessAbstract
To enhance the echocardiographic identification of high risk lesions in patients with infectious endocarditis, the medical records and two-dimensional echocardiograms of 204 patients with this condition were analyzed. The occurrence of specific clinical complications was recorded and vegetations were assessed with respect to predetermined morphologic characteristics. The overall complication rates were roughly equivalent for patients with mitral (53%), aortic (62%), tricuspid (77%) and prosthetic valve (61%) vegetations, as well as for those with nonspecific valvular changes but no discrete vegetations (57%), although the distribution of specific complications varied considerably among these groups. There were significantly fewer complications in patients without discernible valvular abnormalities (27%). In native left-sided valve endocarditis, vegetation size, extent, mobility and consistency were all found to be significant univariate predictors of complications. In multivariate analysis, vegetation size, extent and mobility emerged as optimal predictors and an echocardiographic score based on these factors predicted the occurrence of complications with 70% sensitivity and 92% specificity in mitral valve endocarditis and with 76% sensitivity and 62% specificity in aortic valve endocarditis.
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“Several studies with TTE have demonstrated a trend toward higher embolic rates with left-sided vegetations >1 cm in diameter.55”
From Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association (2015) · cites this paper as [55]
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“Systemic embolization occurs in 22% to 50% of cases of IE. 55,57,[274][275][276][277]”
From Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association (2015) · cites this paper as [55]
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Citations
Cites
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Echocardiography in Bacterial Endocarditis
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Self-citationJaffe, W. M., Morgan, D. E., Pearlman, A. S., & Otto, C. M. (1990) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(10)80005-1 · Cited by 186
Spectrum of echocardiographic findings in bacterial endocarditis.
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Influence of vegetation size on clinical outcome of right-sided infective endocarditis
Robbins, M. J., Frater, R. W. M., Soeiro, R., Frishman, W. H., & Strom, J. A. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90004-5 · Cited by 146
Two-dimensional echocardiographic assessment of vegetative endocarditis.
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Clinical utility of two dimensional echocardiography in infective endocarditis
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Research works printed but not linked: 2
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- Chan, 1989, Transesophageal echocardiology is crucial in the management of endocarditis (abstr), Circulation, 80, II
Cited by
Sorted by citations
Items 301–327 of 327
Erregerbedingte Endokarditiden
Schwinger, R. H. G. (2005) · Springer eBooks · doi:10.1007/3-540-29425-2_15
Múnera, A. G., & Acevedo, C. (2021) · Acta Médica Colombiana · doi:10.36104/amc.2021.1930
FASE, E. K. K. M. F., MHS, E. F. M., & Plotnick, G. D. (2004) · Wiley eBooks · doi:10.1002/9780470988435.furread
Infective Endocarditis and Its Mimics inCriticalCare
Brusch, J. L. (2009) · Infectious disease and therapy · doi:10.3109/9781420092417.013
Starke, J. R. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-4044-6.50037-6
Horstkotte, D. (1995) · Steinkopff eBooks · doi:10.1007/978-3-642-93683-8_12
Echocardiographic Evaluation Of Mitral Valve
Özbek, C., Ufuk Yetk, N., Göktoğan, T., Postac, N., Yeşil, M., & Gürbüz, A. (2007) · The Internet Journal of Thoracic and Cardiovascular Surgery · doi:10.5580/7e0
Lisi, M., Mondillo, S., & Galderisi, M. (2011) · Springer eBooks · doi:10.1007/978-1-84882-521-5_6
van Dantzig, J. M. (2015) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-0752-4_18
Homma, S., & Grahame-Clarke, C. N. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.12.028
Ricketts, J. C., & Jacob, J. T. (2020) · Springer eBooks · doi:10.1007/978-3-030-47868-1_15
Holzheimer, R. G., Horstkotte, D., Kühl, U., Niebel, J., Piper, C., Wiemer, M., Horstkotte, D., Kühl, U., Wienner, M., & Piper, C. (2004) · Springer eBooks · doi:10.1007/978-3-642-18577-9_12
Echokardiographische Diagnostik
Daniel, W. G., Mügge, A., & Nonnast-Daniel, B. (1994) · Steinkopff eBooks · doi:10.1007/978-3-642-87079-8_11
van Dantzig, J. M. (2009) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-313-7565-3_18
Role of Transthoracic and Transesophageal Echocardiography in the Management of Endocarditis
Johnson, C. B., & Chan, K. (2016) · Springer eBooks · doi:10.1007/978-3-319-27784-4_7
(1992) · Journal of Vascular and Interventional Radiology · doi:10.1016/s1051-0443(92)72208-8
Baztarrica, G. P., Tripicchio, G., Berrospi, P. S., Orozco, L. G. C., Chiriboga, N. J., Ortega, R. C., Cubas, E. M., Astudillo, D. G., Zamora, J. R., & Pérez, J. P. (2023) · Anales de la Facultad de Ciencias Médicas (Asunción) · doi:10.18004/anales/2023.056.02.102
Kalp Damar Cerrahisinde Güncel Yaklaşımlar
Tüfekçi, N., Orak, Y., Taş, S., Aladağ, E., Akkaya, İ. O., Doğduş, M., Erol, S., Şahin, Ö., Tunçer, B., Bozdoğan, D., et al. (2022) · Akademisyen Kitabevi eBooks · doi:10.37609/akya.1186
In Memoriam: Arthur E. Weyman, MD, FASE
Picard, M. H., Marshall, J. E., Gillam, L. D., Thomas, J. D., Flachskampf, F. A., & Pearlman, A. S. (2024) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2024.08.002
Self-citationEchocardiographic Evaluation of Complications after Intracardiac Devices Implantation
Toader, D.-M. (2024) · Springer eBooks · doi:10.1007/978-3-031-64079-7_10
Assessing And Managing Embolic Risk in Left-Sided Infective Endocarditis
Román, J. A. S., Sevilla, T., Villalba, G. C., López, J., de Miguel, M., Orive, A. O., Olmos, C., & Vilacosta, I. (2025) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2025.10.025
Lisi, M., Cameli, M., Mondillo, S., & Henein, M. Y. (2025) · Springer eBooks · doi:10.1007/978-3-031-95894-6_6
Yeo, T. C. (2026) · Springer eBooks · doi:10.1007/978-981-96-7667-5_9
Infective Endocarditis Diagnosed by Emergency Physicians Using Cardiac POCUS : A Case Series
Henry, J., Rugless, M., Radeanu, C., Waliuddin, A., Phang, K., Whitehead, A., Khader, S., Henry, D., & Haji, D. L. (2026) · Australasian Journal of Ultrasound in Medicine · doi:10.1002/ajum.70051
Karimy, T. E., Rizkou, H., Elmasrioui, J., & Elhattaoui, M. (2026) · Cureus · doi:10.7759/cureus.116161
Herzinsuffizienz — aus intensivmedizinischer Sicht
Hermann, H., Holubarsch, C., Konstantinides, S., & Hasenfuss, G. P. (2006) · Steinkopff eBooks · doi:10.1007/3-7985-1630-8_23
Metadata
- Authors
- Sanfilippo, A. J., Picard, M. H., Newell, J. B., Rosas, E., Davidoff, R., Thomas, J. D., & Weyman, A. E.
- Affiliations
- Massachusetts General Hospital (US)
- Harvard University (US)
- Corresponding author
- Sanfilippo, Anthony J.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 1991-11
- Volume
- 18
- Issue
- 5
- Pages
- 1191-1199
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2091438055
- Semantic Scholar
- 77cbe2ef81fa55b216750cf99958a15b75b73716
- Cited by
- 328
- References
- 23
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 5 · 2020: 8 · 2019: 6 · 2018: 6 · 2017: 8 · 2016: 9 · 2015: 12 · 2014: 9 · 2013: 13 · 2012: 9
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5t32hl007535-08)
- National Heart, Lung, and Blood Institute (HL-07535)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Infective Endocarditis Diagnosis and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
- Health Sciences › Medicine › Infectious Diseases › Streptococcal Infections and Treatments
- Keywords
- infective endocarditis, echocardiographic assessment, vegetation characteristics, complication prediction, vegetation size, mitral valve endocarditis, aortic valve endocarditis, tricuspid valve endocarditis, prosthetic valve endocarditis, risk stratification
- MeSH terms
- Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents, Aortic Valve, Echocardiography, Endocarditis, Bacterial, Female, Heart Valve Prosthesis, Humans, Male, Middle Aged, Mitral Valve, Predictive Value of Tests, Regression Analysis, Sensitivity and Specificity, Survival Rate
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