Cited by 455Palliative Care and End-of-Life IssuesPalliative and Oncologic CarePain Management and Opioid Use

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Prevalence of symptoms among patients with advanced cancer: An international collaborative study

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Vainio, Anneli, Auvinen, Anssi·1996·Journal of Pain and Symptom Management

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Abstract

The aims of this study were (a) to estimate the prevalence of pain and eight other common symptoms in a large population of patients with advanced cancer from different palliative care centers, and (b) to assess the differences in prevalence of the symptoms by primary site. In 1990-1991, the prevalence of eight major symptoms and performance status were assessed prospectively among 1840 cancer patients in seven hospices in Europe, the United States, and Australia. The data were collected at each institution using structured data collection sheets from the World Health Organization's (WHO) Cancer and Palliative Care Unit. The prevalence of moderate to severe pain was 51%, ranging from 43% in stomach cancer to 80% in gynecological cancers. Nausea was most prevalent in gynecological (42%) and stomach (36%) cancers, and dyspnea (46%) in lung cancer. There were statistically significant differences in the prevalence of most symptoms depending on the primary site of cancer and the hospice. Population-based follow-up studies are needed to document the incidence and prevalence of symptoms throughout the course of the disease.

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Authors: Vainio, A., & Auvinen, A.
Affiliations: World Health Organization (CH)
Finnish Cancer Registry (FI)
ORCID: Auvinen, Anssi
Venue: Journal of Pain and Symptom Management
Publisher: Elsevier BV
Published: 1996-07
Volume: 12
Issue: 1
Pages: 3-10
ISSN: 0885-3924 (ISSN-L)
DOI: 10.1016/0885-3924(96)00042-5
OpenAlex: W2075464999
Cited by: 455
References: 36
Citations by year: 2026: 3 · 2025: 5 · 2024: 8 · 2023: 8 · 2022: 9 · 2021: 11 · 2020: 10 · 2019: 13 · 2018: 16 · 2017: 10 · 2016: 13 · 2015: 10 · 2014: 10 · 2013: 18 · 2012: 21
FWCI: 12.10
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 8596 d)
Locations: Journal of Pain and Symptom Management (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords: advanced cancer, symptom prevalence, cancer pain, nausea, dyspnea, performance status, primary tumor site, gynecologic cancer, gastric cancer, lung cancer, hospice care, palliative care
MeSH terms: Humans, Neoplasms, Pain, Palliative Care

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