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Flavonoids as superoxide scavengers and antioxidants
Open accessAbstract
The superoxide anions scavenging activity and antioxidation of seven flavonoids--quercetin, rutin, morin, acacetin, hispidulin, hesperidin, and naringin--were studied. The superoxide anions were generated in a phenazin methosulphate-NADH system and were assayed by reduction of nitroblue tetrazolium. The scavenging activity ranked: rutin was the strongest, and quercetin and naringin the second, while morin and hispidulin were very weak. The concentration values yielding 50% inhibition of lipid peroxidation in mouse liver homogenate were in order of 10(-6) M for quercetin, rutin, and morin; and of 10(-5) M for acacetin and hispidulin, while naringin and hesperidin had no antioxidative action. In comparison with the antioxidative and scavenging activities of flavonoids, there are no correlations.
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Cited by
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Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02227-9 · Cited by 9,085
Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance
Bravo, L. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1998.tb01670.x · Cited by 4,030
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Havsteen, B. H. (2002) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(02)00298-x · Cited by 2,672
Flavonoids--Chemistry, metabolism, cardioprotective effects, and dietary sources
Cook, N. (1996) · The Journal of Nutritional Biochemistry · doi:10.1016/0955-2863(95)00168-9 · Cited by 2,364
Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical
Nanjo, F., Goto, K., Seto, R., Suzuki, M., Sakai, M., & Hara, Y. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(96)00237-7 · Cited by 783
Metadata
- Authors
- Yuting, C., Rongliang, Z., Zhongjian, J., & Yong, J.
- Venue
- Free Radical Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 1990
- Volume
- 9
- Issue
- 1
- Pages
- 19-21
- ISSN
- 0891-5849 (ISSN-L)
- OpenAlex
- W1964994058
- Cited by
- 588
- References
- 0
- FWCI
- 8.50
- Type
- journal article
- Language
- en
- Open access
- green
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