The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Retinal ganglion cells express a cGMP-gated cation conductance activatable by nitric oxide donors
Open accessAbstract
We have identified a putative cGMP-gated cation conductance in rat retinal ganglion cells. Both in situ hybridization and polymerase chain reaction amplification detected transcripts in ganglion cells that were highly homologous to the cGMP-gated cation channel expressed in rod photoreceptors. Whole-cell patch-clamp recordings detected a current stimulated by cGMP due to activation of nonselective cation channels. This current had a reversal potential near 0 mV, showed some outward rectification, and could be blocked by Cd2+. The current could also be activated by a phosphodiesterase inhibitor and the nitric oxide donors sodium nitroprusside and S-nitrosocysteine. We propose that nitric oxide released from an identified subpopulation of amacrine cells may activate this channel to modulate ganglion cell activity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nitric oxide: physiology, pathophysiology, and pharmacology.
Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06663-3 · Cited by 15,525
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Cited by
Nitric Oxide Signaling in the Central Nervous System
Garthwaite, J., & Boulton, C. L. (1995) · Annual Review of Physiology · doi:10.1146/annurev.ph.57.030195.003343 · Cited by 1,638
Meyer, J. S., Howden, S. E., Wallace, K. A., Verhoeven, A. D., Wright, L. S., Capowski, E. E., Pinilla, I., Martin, J. M., Tian, S., Stewart, R., et al. (2011) · Stem Cells · doi:10.1002/stem.674 · Cited by 469
Coburn, C. M., & Bargmann, C. I. (1996) · Neuron · doi:10.1016/s0896-6273(00)80201-9 · Cited by 438
Prinsen, C. F. M., Szerencsei, R. T., & Schnetkamp, P. P. M. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-04-01424.2000 · Cited by 87
“Nonsensory cGMP-gated channels have been identified in retinal ganglion cells by whole-cell patch-clamp studies (Ahmad et al., 1994; Thompson, 1997; Kawai and Sterling, 1999).”
BackgroundNitric oxide synthase activity in tissues of the bovine eye
Geyer, O., Podos, S. M., & Mittag, T. (1997) · Graefes Archive for Clinical and Experimental Ophthalmology · doi:10.1007/bf02332864 · Cited by 41
Metadata
- Authors
- Ahmad, I., Leinders-Zufall, T., Kocsis, J. D., Shepherd, G. M., Zufall, F., & Barnstable, C. J.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 1994-01
- Volume
- 12
- Issue
- 1
- Pages
- 155-165
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2074293349
- Cited by
- 235
- References
- 2
- FWCI
- 9.56
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Retinal ganglion cells express a cGMP-gated cation conductance activatable by nitric oxide donors. https://app.cochat.ai/papers/10.1016/0896-6273(94)90160-0
- The paper
- Ahmad, I., Leinders-Zufall, T., Kocsis, J. D., Shepherd, G. M., Zufall, F., & Barnstable, C. J. (1994). Retinal ganglion cells express a cGMP-gated cation conductance activatable by nitric oxide donors. Neuron. https://doi.org/10.1016/0896-6273(94)90160-0
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
