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Leukocyte—endothelial cell interactions

McEver, Rodger P.·1992·Current Opinion in Cell Biology
DOI 10.1016/0955-0674(92)90109-p
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Abstract

The movement of leukocytes from the blood circulation into organized lymphoid tissues or sites of inflammation requires cooperative interactions between signaling and adhesion molecules. Selectins mediate the initial rolling contacts of leukocytes with the endothelium. Following leukocyte activation, integrins strengthen adhesion and then direct migration beneath the endothelium. Unique combinations of signaling and adhesion molecules may regulate the subsets of leukocytes that are recruited into specific tissues.

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Research works printed but not linked: 67

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Metadata

Authors
McEver, R. P.
Venue
Current Opinion in Cell Biology
Publisher
Elsevier BV
Published
1992-10
Volume
4
Issue
5
Pages
840-849
ISSN
0955-0674
DOI
10.1016/0955-0674(92)90109-p
Cited by
128
References
1
Language
en
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CoChat. (2026). Citation check: Leukocyte—endothelial cell interactions. https://app.cochat.ai/papers/10.1016/0955-0674(92)90109-p
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McEver, R. P. (1992). Leukocyte—endothelial cell interactions. Current Opinion in Cell Biology. https://doi.org/10.1016/0955-0674(92)90109-p