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Cited by 434

The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.

Technical aspects and challenges of colorimetric detection with microfluidic paper-based analytical devices (μPADs) - A review

Open access
Morbioli, Giorgio Gianini, Mazzu-Nascimento, Thiago, Stockton, Amanda M., Carrilho, Emanuel·2017·Analytica Chimica Acta

Abstract

Paper-based devices are a leading alternative among the main analytical tools for point-of-care testing, due to their portability, low-cost, and ease-of-use. Colorimetric readouts are the most common method of detection in these microfluidic devices, enabling qualitative, semi-quantitative and fully quantitative analysis of multiple analytes. There is a multitude of ways to obtain a colorimetric output in such devices, including nanoparticles, dyes, redox and pH indicators, and each has unique drawbacks and benefits. There are also multiple variables that impact the analysis of colorimetric reactions in microfluidic paper-based systems, including color homogeneity, image capture methods, and the data handling itself. Here, we present a critical review of recent developments and challenges of colorimetric detection on microfluidic paper-based analytical devices (μPADs), and present thoughts and insights towards future perspectives in the area to improve the use of colorimetric readouts in conjunction with μPADs.

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Metadata

Authors
Morbioli, G. G., Mazzu-Nascimento, T., Stockton, A. M., & Carrilho, E.
Venue
Analytica Chimica Acta
Publisher
Elsevier BV
Published
2017-06
Volume
970
Pages
1-22
ISSN
0003-2670 (ISSN-L)
OpenAlex
W2601303661
Cited by
434
References
78
FWCI
16.30
Type
journal article
Language
en
Open access
hybrid

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Morbioli, G. G., Mazzu-Nascimento, T., Stockton, A. M., & Carrilho, E. (2017). Technical aspects and challenges of colorimetric detection with microfluidic paper-based analytical devices (μPADs) - A review. Analytica Chimica Acta. https://doi.org/10.1016/j.aca.2017.03.037

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