The DOI matches its Crossref record; 199 of the 199 references it cites were found in a registry or an index.
Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy
Abstract
Among various nanoparticles, superparamagnetic iron oxide nanoparticles (SPIONs) have been increasingly studied for their excellent superparamagnetism, magnetic heating properties, and enhanced magnetic resonance imaging (MRI). The conjugation of SPIONs with drugs to obtain delivery nanosystems has several advantages including magnetic targeted functionalization, in vivo imaging, magnetic thermotherapy, and combined delivery of anticancer agents. To further increase the targeting efficiency of drugs through a delivery nanosystem based on SPIONs, additional targeting moieties including transferrin, antibodies, aptamers, hyaluronic acid, folate, and targeting peptides are coated onto the surface of SPIONs. Therefore, this review summarizes the latest progresses in the conjugation of targeting molecules and drug delivery nanosystems based on SPIONs, especially focusing on their performances to develop efficient targeted drug delivery systems for tumor therapy.
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Cited by
Magnetic Nanoparticles as MRI Contrast Agents
Avasthi, A., Caro, C., Pozo-Torres, E., Leal, M. P., & García-Martín, M. L. (2020) · Topics in Current Chemistry · doi:10.1007/s41061-020-00302-w · Cited by 253
Gupta, R., Chauhan, A., Kaur, T., Kuanr, B. K., & Sharma, D. (2022) · Nanoscale · doi:10.1039/d2nr02210a · Cited by 35
Metadata
- Authors
- Zhi, D., Yang, T., Yang, J., Fu, S., & Zhang, S.
- Venue
- Acta Biomaterialia
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 102
- Pages
- 13-34
- ISSN
- 1742-7061 (ISSN-L)
- OpenAlex
- W2990574737
- Cited by
- 283
- References
- 199
- FWCI
- 6.32
- Type
- journal article
- Language
- en
- Open access
- closed
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