The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Early-onset drug use and risk for drug dependence problems
Open accessAbstract
There is substantial evidence that alcohol, tobacco, and cannabis dependence problems surface more quickly when use of these drugs starts before adulthood, but the evidence based on other internationally regulated drugs (e.g., cocaine) is meager. With focus on an interval of up to 24 months following first drug use, we examine drug-specific and age-specific variation in profiles of early-emerging clinical features associated with drug dependence. Based upon the United States National Surveys on Drug Use and Health (NSDUH) conducted in 2000-2002, the risk of experiencing drug dependence problems was robustly greater for adolescent recent-onset users of cocaine, psychostimulant drugs other than cocaine, analgesics, anxiolytic medicines, inhalants drugs, and cannabis, as compared to adult recent-onset users (odds ratio=1.5-4.3, p<0.05). This was not the case for the NSDUH hallucinogens group (e.g., LSD). The adolescent onset associated excess risk was not constant across all clinical features. Our evidence suggests promoting earlier detection and interventions, as well as greater parent and peer awareness of drug dependence clinical features that may develop early among young people who have just started using drugs.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Adolescence is a particularly vulnerable time for initiating drug use and developing SUDs.”
From Impact of Sleep and Circadian Rhythms on Addiction Vulnerability in Adolescents (2018) · cites this paper as [1]
In the citing paper
“earlier use (11–17 years of age) predicts later dependence (i.e., within 2 years) for almost every drug of abuse (1)”
From Impact of Sleep and Circadian Rhythms on Addiction Vulnerability in Adolescents (2018) · cites this paper as [1]
In the citing paper
“Early onset of drug abuse is strongly related to the development of lifelong addiction (1,2)”
From Impact of Sleep and Circadian Rhythms on Addiction Vulnerability in Adolescents (2018) · cites this paper as [1]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The adolescent brain and age-related behavioral manifestations
Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433
Chambers, R. A., Taylor, J. R., & Potenza, M. N. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.6.1041 · Cited by 1,719
Multivariate Regression Analyses for Categorical Data
Liang, K., Zeger, S. L., & Qaqish, B. F. (1992) · Journal of the Royal Statistical Society Series B (Statistical Methodology) · doi:10.1111/j.2517-6161.1992.tb01862.x · Cited by 766
Escalation of Drug Use in Early-Onset Cannabis Users vs Co-twin Controls
Lynskey, M. T., Heath, A. C., Bucholz, K. K., Slutske, W. S., Madden, P. A. F., Nelson, E. C., Statham, D. J., & Martin, N. G. (2003) · JAMA · doi:10.1001/jama.289.4.427 · Cited by 656
Neurobehavioral disinhibition in childhood predicts early age at onset of substance use disorder
Tarter, R. E., Kirisci, L., Mezzich, A., Cornelius, J. R., Pajer, K., Vanyukov, M., Gardner, W., Blackson, T., & Clark, D. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.6.1078 · Cited by 655
Grant, B. F., & Dawson, D. A. (1998) · Journal of Substance Abuse · doi:10.1016/s0899-3289(99)80131-x · Cited by 582
Early-onset drug use and risk of later drug problems
Anthony, J. C., & Petronis, K. R. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(95)01194-3 · Cited by 531
King, K. M., & Chassin, L. (2007) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2007.68.256 · Cited by 348
Laviola, G., Adriani, W., Terranova, M. L., & Gerra, G. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00032-9 · Cited by 345
What predicts incident use of cannabis and progression to abuse and dependence?
von Sydow, K., Lieb, R., Pfister, H., Höfler, M., & Wittchen, H.-U. (2002) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00102-3 · Cited by 301
Chen, C.-Y., O’Brien, M. S., & Anthony, J. C. (2005) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.11.014 · Cited by 260
Origins and Consequences of Age at First Drink. II. Familial Risk and Heritability
McGue, M. K., Iacono, W. G., Legrand, L. N., & Elkins, I. J. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2001.tb02331.x · Cited by 193
Early Reactions to Cannabis Predict Later Dependence
Fergusson, D. M., Horwood, L. J., Lynskey, M. T., & Madden, P. A. F. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.10.1033 · Cited by 166
Chen, C., & Anthony, J. C. (2002) · Addiction · doi:10.1046/j.1360-0443.2003.00237.x · Cited by 110
Höfler, M., Lieb, R., Perkonigg, A., Schuster, P., Sonntag, H., & Wïttchen, H. (1999) · Addiction · doi:10.1046/j.1360-0443.1999.941116796.x · Cited by 106
Overview of Findings from the 2003 National Survey on Drug Use and Health
Administration, S. A. A. M. H. S. (2004) · PsycEXTRA Dataset · doi:10.1037/e400452005-001 · Cited by 83
Storr, C. L., Zhou, H., Liang, K., & Anthony, J. C. (2004) · Nicotine & Tobacco Research · doi:10.1080/14622200410001696493 · Cited by 55
Longitudinal patterns of tobacco smoking from childhood to middle age
Janson, H. (1999) · Addictive Behaviors · doi:10.1016/s0306-4603(98)00061-6 · Cited by 40
Anthony, J. C., Chen, C., & Storr, C. L. (2005) · Clinical Neuroscience Research · doi:10.1016/j.cnr.2005.08.002 · Cited by 23
Principles of disease prevention from discovery to application
Wynder, E. L. (1994) · Sozial- und Präventivmedizin · doi:10.1007/bf01298837 · Cited by 6
Cited by
Sorted by citations
Adverse health effects of marijuana use.
Volkow, N. D., Baler, R. D., Compton, W. M., & Weiss, S. R. B. (2014) · New England Journal of Medicine · doi:10.1056/nejmra1402309 · Cited by 2,774
Office of National Drug Control Policy
Madras, B. K. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05278.x · Cited by 859
US epidemiology of cannabis use and associated problems
Hasin, D. S. (2018) · Neuropsychopharmacology · doi:10.1038/npp.2017.198 · Cited by 578
The epidemiology of benzodiazepine misuse: A systematic review*
Votaw, V. R., Geyer, R., Rieselbach, M. M., & McHugh, R. K. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.02.033 · Cited by 479
McGorry, P. D., Purcell, R., Goldstone, S., & Amminger, G. P. (2011) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e3283477a09 · Cited by 490
Metadata
- Authors
- Chen, C.-Y., Storr, C. L., & Anthony, J. C.
- Affiliations
- National Health Research Institutes (TW)
- University of Maryland, Baltimore (US)
- Michigan State University (US)
- Corresponding author
- Storr, Carla L.
- Venue
- Addictive Behaviors
- Publisher
- Elsevier BV
- Published
- 2009-03
- Volume
- 34
- Issue
- 3
- Pages
- 319-322
- ISSN
- 0306-4603 (ISSN-L)
- PMC
- PMC2677076
- OpenAlex
- W1965773300
- Cited by
- 466
- References
- 20
- Citations by year
- 2026: 15 · 2025: 28 · 2024: 21 · 2023: 27 · 2022: 36 · 2021: 36 · 2020: 48 · 2019: 23 · 2018: 37 · 2017: 32 · 2016: 31 · 2015: 34 · 2014: 31 · 2013: 23 · 2012: 17
- FWCI
- 6.43
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Addictive Behaviors (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Health Research Institutes
- National Institute on Drug Abuse (R01 DA09897, R01DA016323, K05DA015799, R01DA009897)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Youth, Drugs, and Violence
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- adolescent drug use, drug addiction, cocaine dependence, psychostimulants, cannabis use disorder, inhalant use, analgesic dependence, hallucinogens, age of onset, substance use prevention
- MeSH terms
- Adolescent, Age Factors, Female, Humans, Health Knowledge, Attitudes, Practice, Male, Risk Factors, Substance-Related Disorders, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review