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Carbon nanotubes as nanomedicines: From toxicology to pharmacology☆
Abstract
Various biomedical applications of carbon nanotubes have been proposed in the last few years leading to the emergence of a new field in diagnostics and therapeutics. Most of these applications will involve the administration or implantation of carbon nanotubes and their matrices into patients. The toxicological and pharmacological profile of such carbon nanotube systems developed as nanomedicines will have to be determined prior to any clinical studies undertaken. This review brings together all the toxicological and pharmacological in vivo studies that have been carried out using carbon nanotubes, to offer the first summary of the state-of-the-art in the pharmaceutical development of carbon nanotubes on the road to becoming viable and effective nanomedicines.
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Cites
Donaldson, K., Aitken, R., Tran, L., Stone, V., Duffin, R., Forrest, G., & Alexander, A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj130 · Cited by 1,167
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Zhang, Q., Huang, J., Qian, W., Zhang, Y., & Wei, F. (2013) · Small · doi:10.1002/smll.201203252 · Cited by 759
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Cai, W., & Chen, X. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.045922 · Cited by 494
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Metadata
- Authors
- LACERDA, L., BIANCO, A., PRATO, M., & KOSTARELOS, K.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2006-12-01
- Volume
- 58
- Issue
- 14
- Pages
- 1460-1470
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2162459979
- Cited by
- 839
- References
- 1
- FWCI
- 37.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- LACERDA, L., BIANCO, A., PRATO, M., & KOSTARELOS, K. (2006). Carbon nanotubes as nanomedicines: From toxicology to pharmacology☆. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2006.09.015
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.