The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.
Heparin coatings for improving blood compatibility of medical devices
Open accessAbstract
Blood contact with biomaterials triggers activation of multiple reactive mechanisms that can impair the performance of implantable medical devices and potentially cause serious adverse clinical events. This includes thrombosis and thromboembolic complications due to activation of platelets and the coagulation cascade, activation of the complement system, and inflammation. Numerous surface coatings have been developed to improve blood compatibility of biomaterials. For more than thirty years, the anticoagulant drug heparin has been employed as a covalently immobilized surface coating on a variety of medical devices. This review describes the fundamental principles of non-eluting heparin coatings, mechanisms of action, and clinical applications with focus on those technologies which have been commercialized. Because of its extensive publication history, there is emphasis on the CARMEDA ® BioActive Surface (CBAS ® Heparin Surface), a widely used commercialized technology for the covalent bonding of heparin.
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Intracoronary Stenting Without Anticoagulation Accomplished With Intravascular Ultrasound Guidance
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Temporal Aspects of Heparin-Induced Thrombocytopenia
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Medical device‐induced thrombosis: what causes it and how can we prevent it?
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The separation of active and inactive forms of heparin
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Delayed-Onset Heparin-Induced Thrombocytopenia and Thrombosis
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Heparin Bonding on Colloidal Graphite Surfaces
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Cited by
Osman, A. I., Chen, Z., Elgarahy, A. M., Farghali, M., Mohamed, I. M. A., Priya, A. K., Hawash, H. B., & Yap, P. (2024) · Advanced Energy and Sustainability Research · doi:10.1002/aesr.202400011 · Cited by 365
Metadata
- Authors
- Biran, R., & Pond, D.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 112
- Pages
- 12-23
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2563390568
- Cited by
- 334
- References
- 75
- FWCI
- 0.76
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
