The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Randomized Multicenter Comparison of Conventional Anticoagulation Versus Antiplatelet Therapy in Unplanned and Elective Coronary Stenting: The Full Anticoagulation Versus Aspirin and Ticlopidine (FANTASTIC) Study
Open accessAbstract
Background —Dual therapy with ticlopidine and aspirin has been shown to be as effective as or more effective than conventional anticoagulation in patients with an optimal result after implantation of intracoronary metallic stents. However, the safety and efficacy of antiplatelet therapy alone in an unselected population has not been evaluated. Methods —Patients were randomized to conventional anticoagulation or to treatment with antiplatelet therapy alone. Indications for stenting were classified as elective (decided before the procedure) or unplanned (to salvage failed angioplasty or to optimize the results of balloon angioplasty). After stenting, patients received aspirin and either ticlopidine or conventional anticoagulation (heparin or oral anticoagulant). The primary end point was the occurrence of bleeding or peripheral vascular complications; secondary end points were cardiac events (death, infarction, or stent occlusion) and duration of hospitalization. Results —In 13 centers, 236 patients were randomized to anticoagulation and 249 to antiplatelet therapy. Stenting was elective in 58% of patients and unplanned in 42%. Stent implantation was successfully achieved in 99% of patients. A primary end point occurred in 33 patients (13.5%) in the antiplatelet group and 48 patients (21%) in the anticoagulation group (odds ratio=0.6 [95% CI 0.36 to 0.98], P =0.03). Major cardiac-related events in electively stented patients were less common (odds ratio=0.23 [95% CI 0.05 to 0.91], P =0.01) in the antiplatelet group (3 of 123, 2.4%) than the anticoagulation group (11 of 111, 9.9%). Hospital stay was significantly shorter in the antiplatelet group (4.3±3.6 versus 6.4±3.7 days, P =0.0001). Conclusions —Antiplatelet therapy after coronary stenting significantly reduced rates of bleeding and subacute stent occlusion compared with conventional anticoagulation.
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Serruys, P. W., de Jaegere, P., Kiemeneij, F., Macaya, C., Rutsch, W., Heyndrickx, G., Emanuelsson, H., Marco, J., Legrand, V., Materne, P., et al. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408253310801 · Cited by 4,556
Self-citationFischman, D. L., Leon, M. B., Baim, D. S., Schatz, R. A., Savage, M. P., Penn, I., Detre, K., Veltri, L., Ricci, D., Nobuyoshi, M., et al. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408253310802 · Cited by 4,271
Ryan, T. J., Faxon, D. P., Gunnar, R. M., Kennedy, J. W., King, S. B., Loop, F. D., Peterson, K. L., Reeves, T. J., Williams, D. O., & Winters, W. L. (1988) · Circulation · doi:10.1161/01.cir.78.2.486 · Cited by 2,123
Schömig, A., Neumann, F.-J., Kastrati, A., Schühlen, H., Blasini, R., Hadamitzky, M., Walter, H., Zitzmann-Roth, E.-M., Richardt, G., Alt, E., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199604253341702 · Cited by 2,028
Intracoronary Stenting Without Anticoagulation Accomplished With Intravascular Ultrasound Guidance
Colombo, A., Hall, P., Nakamura, S., Almagor, Y., Maiello, L., Martini, G., Gaglione, A., Goldberg, S. L., & Tobis, J. M. (1995) · Circulation · doi:10.1161/01.cir.91.6.1676 · Cited by 1,428
Ryan, T. J., Bauman, W. B., Kennedy, J. W., Kereiakes, D. J., King, S. B., McCallister, B. D., Smith, S. C., & Ullyot, D. J. (1993) · Circulation · doi:10.1161/01.cir.88.6.2987 · Cited by 399
Hall, P., Nakamura, S., Maiello, L., Itoh, A., Blengino, S., Martini, G., Ferraro, M., & Colombo, A. (1996) · Circulation · doi:10.1161/01.cir.93.2.215 · Cited by 281
Gregorini, L., Marco, J., Fajadet, J. C., Bernies, M., Cassagneau, B. G., Brunel, P., Bossi, I. M., & Mannucci, P. M. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00428-7 · Cited by 110
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Steinhubl, S. R., Berger, P. B., Mann III, J. T., Fry, E. T. A., DeLago, A., Wilmer, C., Topol, E. J., & for the CREDO Investigators (2002) · JAMA · doi:10.1001/jama.288.19.2411 · Cited by 3,078
Guidelines for Percutaneous Coronary Interventions
Silber, S., Albertsson, P., Avilés, F. F., Camici, P. G., Colombo, A., Hamm, C., Jørgensen, E., Marco, J., Nordrehaug, J.-E., Ruzyllo, W., et al. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi138 · Cited by 1,609
Price, M. J. (2011) · JAMA · doi:10.1001/jama.2011.290 · Cited by 1,308
Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation
Lopes, R. D., Heizer, G., Aronson, R., Vora, A. N., Massaro, T., Mehran, R., Goodman, S. G., Windecker, S., Darius, H., Li, J., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1817083 · Cited by 1,228
Montalescot, G., Wiviott, S. D., Braunwald, E., Murphy, S. A., Gibson, C. M., McCabe, C. H., & Antman, E. M. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60441-4 · Cited by 1,068
Metadata
- Authors
- Bertrand, M. E., Legrand, V., Boland, J., Fleck, E., Bonnier, J., Emmanuelson, H., Vrolix, M., Missault, L., Chierchia, S., Casaccia, M., Niccoli, L., Oto, A., White, C., Webb-Peploe, M., Van Belle, E., & McFadden, E. P.
- Venue
- Circulation
- Published
- 1998-10-20
- Volume
- 98
- Issue
- 16
- Pages
- 1597-1603
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2121047179
- Cited by
- 583
- References
- 8
- FWCI
- 25.23
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Randomized Multicenter Comparison of Conventional Anticoagulation Versus Antiplatelet Therapy in Unplanned and Elective Coronary Stenting: The Full Anticoagulation Versus Aspirin and Ticlopidine (FANTASTIC) Study. https://app.cochat.ai/papers/10.1161/01.cir.98.16.1597
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- Bertrand, M. E., Legrand, V., Boland, J., Fleck, E., Bonnier, J., Emmanuelson, H., Vrolix, M., Missault, L., Chierchia, S., Casaccia, M., Niccoli, L., Oto, A., White, C., Webb-Peploe, M., Van Belle, E., & McFadden, E. P. (1998). Randomized Multicenter Comparison of Conventional Anticoagulation Versus Antiplatelet Therapy in Unplanned and Elective Coronary Stenting: The Full Anticoagulation Versus Aspirin and Ticlopidine (FANTASTIC) Study. Circulation. https://doi.org/10.1161/01.cir.98.16.1597
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
