Angiotensin inhibition in renovascular disease: A population-based cohort study
Abstract
Background Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers effectively reduce blood pressure in patients with renovascular disease (RVD); yet, randomized cardiovascular prevention trials of these drugs typically exclude individuals with this condition.Patients and methods We studied the association of renin-angiotensin system inhibition with prognosis in a population-based cohort comprising 3,570 patients with RVD in Ontario, Canada; slightly more than half (n = 1,857, 53%) were prescribed angiotensin inhibitors. The primary outcome was the composite of death, myocardial infarction, or stroke. Secondary outcomes included individual cardiovascular and renal events.Results Patients receiving angiotensin inhibitors had a significantly lower risk for the primary outcome during follow-up (10.0 vs 13.0 events per 100 patient-years at risk, multivariable adjusted hazard ratio [HR] 0.70, 95% CI 0.59-0.82). In addition, hospitalization for congestive heart failure (HR 0.69, 95% CI 0.53-0.90), chronic dialysis initiation (HR 0.62, 95% CI 0.42-0.92), and mortality (HR 0.56, 95% CI 0.47-0.68) was lower in treated patients. Conversely, patients receiving angiotensin inhibitors were significantly more likely to be hospitalized for acute renal failure during follow-up (HR 1.87, 95% CI 1.05-3.33; 1.2 vs 0.6 events per 100 patient-years at risk).Conclusions These data emphasize the high vascular risk of RVD and suggest that angiotensin inhibitors may improve prognosis in this setting at the expense of acute renal toxicity. If the latter are selected in the management of RVD, renal function parameters should be assiduously followed.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Large data registries indicate that ACE inhibitor or ARB treatment in patients with identified renal artery stenosis confers a long-term mortality benefit.
“Large data registries indicate that ACE inhibitor or ARB treatment in patients with identified renal artery stenosis confers a long-term mortality benefit.317”
From Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association (2018) · cites this paper as [317]
Cites
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040296 · Cited by 23,020 · see citing works
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-8-200710160-00010 · Cited by 17,796 · see citing works
Des Jarlais, D. C., Lyles, C., Crepaz, N., & the TREND Group (2004) · American Journal of Public Health · doi:10.2105/ajph.94.3.361 · Cited by 2,817 · see citing works
Jafar, T. H., Stark, P. C., Schmid, C. H., Landa, M., Maschio, G., de Jong, P. E., de Zeeuw, D., Shahinfar, S., Toto, R. D., Levey, A. S., et al. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-139-4-200308190-00006 · Cited by 1,143 · see citing works
Safian, R. D., & Textor, S. C. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102083440607 · Cited by 1,104 · see citing works
Casas, J. P., Chua, W., Loukogeorgakis, S., Vallance, P. J., Smeeth, L. L., Hingorani, A. D., & MacAllister, R. J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67814-2 · Cited by 735 · see citing works
Immortal time bias in observational studies of drug effects
Suissa, S. (2007) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1357 · Cited by 593 · see citing works
Austin, P. C., Daly, P. A., & Tu, J. V. (2002) · American Heart Journal · doi:10.1067/mhj.2002.123839 · Cited by 524 · see citing works
Prevalence of renovascular disease in the elderly: A population-based study
Hansen, K. J., Edwards, M. S., Craven, T. E., Cherr, G. S., Jackson, S., Appel, R. G., Burke, G. L., & Dean, R. H. (2002) · Journal of Vascular Surgery · doi:10.1067/mva.2002.127351 · Cited by 496 · see citing works
(2003) · PubMed · Cited by 490 · see citing works
Strippoli, G. F., Craig, M. E., Deeks, J. J., Schena, F. P., & Craig, J. C. (2004) · BMJ · doi:10.1136/bmj.38237.585000.7c · Cited by 379 · see citing works
Lee, D. S., Donovan, L. R., Austin, P. C., Gong, Y., Liu, P. P., Rouleau, J. L., & Tu, J. V. (2005) · Medical Care · doi:10.1097/00005650-200502000-00012 · Cited by 358 · see citing works
Severity of renal vascular disease predicts mortality in patients undergoing coronary angiography
Conlon, P. J., Little, M. A., Pieper, K., & Mark, D. B. (2001) · Kidney International · doi:10.1046/j.1523-1755.2001.00953.x · Cited by 342 · see citing works
Kalra, P. A., Guo, H., Kausz, A. T., Gilbertson, D. T., Liu, J., Chen, S., Ishani, A., Collins, A. J., & Foley, R. N. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.00406.x · Cited by 334 · see citing works
Cooper, C. J., Murphy, T. P., Matsumoto, A. H., Steffes, M. W., Cohen, D. J., Jaff, M. R., Kuntz, R. E., Jamerson, K., Reid, D., Rosenfield, K., et al. (2006) · American Heart Journal · doi:10.1016/j.ahj.2005.09.011 · Cited by 285 · see citing works
Jong, P., Gong, Y., Liu, P. P., Austin, P. C., Lee, D. S., & Tu, J. V. (2003) · Circulation · doi:10.1161/01.cir.0000080290.39027.48 · Cited by 240 · see citing works
Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies
Papanikolaou, P. N. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.050873 · Cited by 229 · see citing works
Potassium disorders—clinical spectrum and emergency management
Alfonzo, A. V. M., Isles, C., Geddes, C., & Deighan, C. (2006) · Resuscitation · doi:10.1016/j.resuscitation.2005.11.002 · Cited by 216 · see citing works
Mindlen, F., Nordaby, R. A., Ruiz, M. I. S., Nava-Zavala, A. H., Guzmán, L., Martínez, F., Díaz, R., Mackey, C., Marino, M., Romero, G. S., et al. (1996) · Canadian Journal of Cardiology · Cited by 151 · see citing works
Renovascular Disease and the Risk of Adverse Coronary Events in the Elderly
Edwards, M. S. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.2.207 · Cited by 140 · see citing works
van de Ven, P. J. G., Beutler, J. J., Kaatee, R., Beek, F. J. A., Mali, W. P. T. M., & Koomans, H. A. (1998) · Kidney International · doi:10.1111/j.1523-1755.1998.00840.x · Cited by 130 · see citing works
Fatica, R. A., Port, F. K., & Young, E. W. (2001) · American Journal of Kidney Diseases · doi:10.1053/ajkd.2001.24521 · Cited by 126 · see citing works
Epidemiology of Renal Dysfunction and Patient Outcome in Atherosclerotic Renal Artery Occlusion
Cheung, C. M., Wright, J. R., Shurrab, A. E., Mamtora, H., Foley, R. N., O'Donoghue, D. J., Waldek, S., & Kalra, P. A. (2002) · Journal of the American Society of Nephrology · doi:10.1681/asn.v131149 · Cited by 112 · see citing works
Reversible renal failure during treatment with captopril.
Farrow, P. R., & Wilkinson, R. W. (1979) · BMJ · doi:10.1136/bmj.1.6179.1680 · Cited by 111 · see citing works
Atherosclerotic Renovascular Disease in Older US Patients Starting Dialysis, 1996 to 2001
Guo, H., Kalra, P. A., Gilbertson, D. T., Liu, J., Chen, S., Collins, A. J., & Foley, R. N. (2006) · Circulation · doi:10.1161/circulationaha.106.637751 · Cited by 95 · see citing works
Hackam, D. G., Spence, J. D., Garg, A. X., & Textor, S. C. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.097345 · Cited by 83 · see citing works
Self-citationReversible renal failure during treatment with captopril.
Collste, P., Haglund, K., Lundgren, G., Magnússon, G., & Östman, J. (1979) · BMJ · doi:10.1136/bmj.2.6190.612-c · Cited by 78 · see citing works
Mui, K.-W., Sleeswijk, M. E., van den Hout, H., van Baal, J. G., Navis, G. J., & Woittiez, A.-J. J. (2006) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005080827 · Cited by 76 · see citing works
Prevention of events with angiotensin-converting enzyme inhibition (the PEACE study design)
Pfeffer, M. A., Domanski, M., Rosenberg, Y., Verter, J. I., Geller, N. L., Albert, P., Hsia, J. A., & D, E. B. M. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00488-3 · Cited by 75 · see citing works
Franklin, S. S., & Smith, R. D. (1985) · The American Journal of Medicine · doi:10.1016/0002-9343(85)90075-0 · Cited by 73 · see citing works
Pillay, W. R., Kan, Y. M., Crinnion, J. N., & Wolfe, J. H. N. (2002) · British journal of surgery · doi:10.1046/j.1365-2168.2002.02144.x · Cited by 70 · see citing works
Jackson, B., Matthews, P. G., Mcgrath, B. P., & Johnston, C. I. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92149-4 · Cited by 54 · see citing works
Devoy, M. A. B., Tomson, C., Edmunds, M. E., Feehally, J., & Walls, J. (1992) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1992.tb00622.x · Cited by 53 · see citing works
Factors affecting long‐term survival following renal artery stenting
Bates, M. C., Campbell, J. E., Stone, P. A., Jaff, M. R., Broce, M., & Lavigne, P. S. (2007) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.21121 · Cited by 52 · see citing works
The EUROPA Trial: Design, Baseline Demography and Status of the Substudies
Gomma, A. H., & Fox, K. (2001) · Cardiovascular Drugs and Therapy · doi:10.1023/a:1011131130922 · Cited by 50 · see citing works
Prevalence and Outcome of Renal Artery Stenosis in Atherosclerotic Patients with Renal Dysfunction.
Uzu, T., Takeji, M., Yamada, N., Fujii, T., Yamauchi, A., Takishita, S., & Kimura, G. (2002) · Hypertension Research · doi:10.1291/hypres.25.537 · Cited by 50 · see citing works
Enalapril in the treatment of hypertension with renal artery stenosis.
Hodsman, G. P., Brown, J. J., Cumming, A. M., Davies, D. L., East, B. W., Lever, A. F., Morton, J. J., Murray, G. D., Robertson, I., & Robertson, J. I. (1983) · BMJ · doi:10.1136/bmj.287.6403.1413 · Cited by 48 · see citing works
Knipp, B. S., Dimick, J. B., Eliason, J. L., Cowan, J. A., Henke, P. K., Proctor, M., Stanley, J. C., & Upchurch, G. R. (2004) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2004.07.029 · Cited by 44 · see citing works
Onuigbo, M. A. C., & Onuigbo, N. T. C. (2005) · PubMed · Cited by 40 · see citing works
(1996) · PubMed · Cited by 40 · see citing works
Blood pressure, antihypertensive medication, and atherosclerotic renal artery stenosis
Tullis, M. J., Caps, M. T., Zierler, R. E., Bergelin, R. O., Polissar, N. L., Cantwell-Gab, K., Davidson, R. C., & Strandness, D. E. (1999) · American Journal of Kidney Diseases · doi:10.1016/s0272-6386(99)70218-0 · Cited by 38 · see citing works
Enalapril (MK421) in the treatment of hypertension with renal artery stenosis.
Hodsman, G. P., Brown, J. J., Cumming, A. M. M., Davies, D. L., East, B. W., Lever, A. F., Morton, J. J., Murray, G. D., & Robertson, J. I. (1983) · PubMed · Cited by 37 · see citing works
Siebenhofer, A., Plank, J., Horvath, K., Berghold, A., Sutton, A. J., Sommer, R., & Pieber, T. R. (2004) · Diabetic Medicine · doi:10.1111/j.1464-5491.2004.01122.x · Cited by 34 · see citing works
Cox, J. L., Mp, M., Chen, E., & Naylor, C. D. (1997) · PubMed · Cited by 34 · see citing works
Edwards, M. S., Hansen, K. J., Craven, T. E., Bleyer, A. J., Burke, G. L., Levy, P. J., & Dean, R. H. (2004) · Vascular and Endovascular Surgery · doi:10.1177/153857440403800103 · Cited by 32 · see citing works
Atherosclerotic renal artery stenosis, ACE inhibitors, and avoiding cardiovascular death
Main, J. (2005) · Heart · doi:10.1136/hrt.2003.019505 · Cited by 27 · see citing works
Johansen, T. L., & Kjær, A. (2001) · BMC Nephrology · doi:10.1186/1471-2369-2-1 · Cited by 24 · see citing works
Treatment options for renovascular hypertension
Spence, J. D. (2002) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.3.4.411 · Cited by 21 · see citing works
Self-citationEnalapril versus Triple-Drug Therapy in the Treatment of Renovascular Hypertension
Reams, G. P., & Bauer, J. H. (1985) · Drugs · doi:10.2165/00003495-198500301-00009 · Cited by 17 · see citing works
Taking precautions with ACE inhibitors
Kumar, A., Asim, M. I., & Davison, A. M. (1998) · BMJ · doi:10.1136/bmj.316.7149.1921 · Cited by 13 · see citing works
Clinical Evaluation of Delapril in Japan
Ogihara, T., Kaneko, Y., Ikeda, M., Yamada, K., Omae, T., Arakawa, K., Ishii, M., YOSHINAGA, K., Kumahara, Y., & Kokubu, T. (1991) · American Journal of Hypertension · doi:10.1093/ajh/4.1.42s · Cited by 13 · see citing works
High-risk patients treated with enalapril maleate: safety considerations
Rucinska, E. J., Small, R. S., & Irvin, J. D. (1989) · International Journal of Cardiology · doi:10.1016/0167-5273(89)90075-2 · Cited by 10 · see citing works
Schwietzer, G., & Oelkers, W. (1982) · Journal of Molecular Medicine · doi:10.1007/bf01728350 · Cited by 9 · see citing works
Yang, J. G., Hu, D., Li, T., Peng, J., Yu, H. Y., Pang, W., Wang, C., Xiao, J., & Xu, Y. (2004) · Hypertension Research · doi:10.1291/hypres.27.339 · Cited by 8 · see citing works
ACE inhibitors and unilateral renal artery stenosis — what price?
Kothari, S. S. (1996) · International Journal of Cardiology · doi:10.1016/0167-5273(95)02541-3 · Cited by 4 · see citing works
[Progressive reversible kidney insufficiency after blood pressure reduction with captopril].
Kindler, J., Konrads, A., Meurer, K. A., & Sieberth, H. G. (1981) · PubMed · Cited by 3 · see citing works
Flagged first, then by citations
1 of the 57 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Aboyans, V., Ricco, J.-B., Bartelink, M.-L. E. L., Björck, M., Brodmann, M., Cohnert, T., Collet, J.-P., Czerny, M., De Carlo, M., Debus, S., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx095 · Cited by 3,293 · see citing works
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
Umemura, S., Arima, H., Arima, S., Asayama, K., Dohi, Y., Hirooka, Y., Horio, T., Hoshide, S., Ikeda, S., Ishimitsu, T., et al. (2019) · Hypertension Research · doi:10.1038/s41440-019-0284-9 · Cited by 1,880 · see citing works
ESC Guidelines on the diagnosis and treatment of peripheral artery diseases
Endorsed by: the European Stroke Organisation (ESO), Authors/Task Force Members, Tendera, M., Aboyans, V., Bartelink, M.-L., Baumgartner, I., Clément, D., Collet, J.-P., Cremonesi, A., De Carlo, M., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr211 · Cited by 1,506 · see citing works
Carey, R. M., Calhoun, D. A., Bakris, G. L., Brook, R. D., Daugherty, S. L., Dennison-Himmelfarb, C. R., Egan, B. M., Flack, J. M., Gidding, S. S., Judd, E., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000084 · Cited by 1,153 · see citing works
2024 ESC Guidelines for the management of peripheral arterial and aortic diseases
Mazzolai, L., Teixidó‐Turà, G., Lanzi, S., Boc, V., Bossone, E., Brodmann, M., Bura-Rivière, A., Backer, J. F. A. D., Déglise, S., Corte, A. D., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae179 · Cited by 1,219 · see citing works
Halliday, A. W., & Bax, J. J. (2018) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2018.03.004 · Cited by 654 · see citing works
Aboyans, V., Ricco, J., Bartelink, M.-L. E. L., Björck, M., Brodmann, M., Cohnert, T. U., Collet, J., Czerny, M., Carlo, M. D., Debus, S., et al. (2017) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2017.07.018 · Cited by 1,006 · see citing works
Renovascular Hypertension and Ischemic Nephropathy
Textor, S. C., & Lerman, L. O. (2010) · American Journal of Hypertension · doi:10.1038/ajh.2010.174 · Cited by 196 · see citing works
Dworkin, L. D., & Cooper, C. J. (2009) · New England Journal of Medicine · doi:10.1056/nejmcp0809200 · Cited by 168 · see citing works
Treating Arteries Instead of Risk Factors
Spence, J. D., & Hackam, D. G. (2010) · Stroke · doi:10.1161/strokeaha.110.577973 · Cited by 156 · see citing works
Self-citationKoelemay, M. J., Geelkerken, R. H., Kärkkäinen, J., Leone, N., Antoniou, G. A., de Bruin, J. L., Gombert, A., Gottsätter, A., Iborra, E., Ronchey, S., et al. (2025) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2025.06.010 · Cited by 123 · see citing works
Cost-effectiveness of enzyme replacement therapy for Fabry disease
Rombach, S. M., Hollak, C. E. M., Linthorst, G. E., & Dijkgraaf, M. G. W. (2013) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-8-29 · Cited by 93 · see citing works
Current Concepts in the Treatment of Renovascular Hypertension
Herrmann, S. M., & Textor, S. C. (2018) · American Journal of Hypertension · doi:10.1093/ajh/hpx154 · Cited by 84 · see citing works
Raman, G., Adam, G. P., Halladay, C. W., Langberg, V. N., Azodo, I. A., & Balk, E. M. (2016) · Annals of Internal Medicine · doi:10.7326/m16-1053 · Cited by 81 · see citing works
Hicks, C. W., Clark, T. W. I., Cooper, C. J., Bhailis, A. M. D., Carlo, M. D., Green, D., Małyszko, J., Miglinas, M., Textor, S. C., Herzog, C. A., et al. (2021) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2021.06.025 · Cited by 85 · see citing works
Ohya, Y., Arakawa, K., Arata, N., Arima, S., Arima, H., Asayama, K., Dohi, Y., Fukami, A., Furuhashi, M., Goto, K., et al. (2026) · Hypertension Research · doi:10.1038/s41440-025-02462-y · Cited by 81 · see citing works
Paradigm Shifts in Atherosclerotic Renovascular Disease
Textor, S. C., & Lerman, L. O. (2015) · Journal of the American Society of Nephrology · doi:10.1681/asn.2014121274 · Cited by 70 · see citing works
Johansen, K. L., Garimella, P. S., Hicks, C. W., Kalra, P. A., Kelly, D., Martens, S., Matsushita, K., Sarafidis, P. A., Sood, M. M., Herzog, C. A., et al. (2021) · Kidney International · doi:10.1016/j.kint.2021.04.029 · Cited by 64 · see citing works
Renal Arterial Disease and Hypertension
Textor, S. C. (2016) · Medical Clinics of North America · doi:10.1016/j.mcna.2016.08.010 · Cited by 63 · see citing works
Clinical practice guideline for the management of hypertension in China
Chinese Society of Cardiology, C. M. A., Hypertension Committee of Cross-Straits Medicine Exchange Association, & Cardiovascular Disease Prevention and Rehabilitation Committee, C. A. O. R. M. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003431 · Cited by 62 · see citing works
Current Approaches to Renovascular Hypertension
Textor, S. C. (2009) · Medical Clinics of North America · doi:10.1016/j.mcna.2009.02.012 · Cited by 56 · see citing works
Diagnosis and treatment of renal artery stenosis
Plouin, P., & Bax, L. (2010) · Nature Reviews Nephrology · doi:10.1038/nrneph.2009.230 · Cited by 51 · see citing works
Piechocki, M., Przewłocki, T., Pieniążek, P., Trystuła, M., Podolec, J., & Kabłak-Ziembicka, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13051471 · Cited by 50 · see citing works
Statins and renovascular disease in the elderly: a population-based cohort study
Hackam, D. G., Wu, F., Li, P., Austin, P. C., Tobe, S. W., Mamdani, M. M., & Garg, A. X. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehq452 · Cited by 49 · see citing works
Self-citationBlood Oxygen Level–Dependent (BOLD) MRI in Renovascular Hypertension
Gloviczki, M. L., Lerman, L. O., & Textor, S. C. (2011) · Current Hypertension Reports · doi:10.1007/s11906-011-0218-7 · Cited by 47 · see citing works
Sarafidis, P. A., Theodorakopoulou, M. P., Ortíz, A., Fernández‐Fernández, B., Nistor, I., Schmieder, R. E., Arıcı, M., Saratzis, A. N., der Niepen, P. V., Halimi, J., et al. (2023) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfad095 · Cited by 45 · see citing works
Use of Renin-Angiotensin Inhibitors in People with Renal Artery Stenosis
Evans, K. L., Tuttle, K. R., Folt, D. A., Dawson, T., Haller, S. T., Brewster, P. S., He, W., Jamerson, K., Dworkin, L. D., Cutlip, D. E., et al. (2014) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.11611113 · Cited by 43 · see citing works
Hypertension and aortorenal disease in Alagille syndrome
Salem, J., Bruguière, É., Iserin, L., Guiochon‐Mantel, A., & Plouin, P. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283531e1f · Cited by 44 · see citing works
Renal Artery Stenosis: When to Revascularize in 2017
Soto, J. T., & White, C. J. (2017) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2017.01.004 · Cited by 44 · see citing works
Soto, J. T., & White, C. J. (2014) · Cardiology Clinics · doi:10.1016/j.ccl.2014.09.006 · Cited by 43 · see citing works
Atherosclerotic Renal Artery Stenosis and Hypertension: Pragmatism, Pitfalls, and Perspectives
Bavishi, C., de Leeuw, P. W., & Messerli, F. H. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2015.10.010 · Cited by 38 · see citing works
Cardiovascular Morbidity and Mortality and Renal Artery Stenosis
Colyer, W. R., & Cooper, C. J. (2009) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2009.09.004 · Cited by 33 · see citing works
Renal Artery Stenosis: Optimizing Diagnosis and Treatment
Colyer, W. R., Eltahawy, E. A., & Cooper, C. J. (2011) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2011.02.007 · Cited by 33 · see citing works
Pappaccogli, M., Robberechts, T., Lengelé, J., der Niepen, P. V., Sarafidis, P. A., Rabbia, F., & Persu, A. (2023) · Hypertension · doi:10.1161/hypertensionaha.122.17965 · Cited by 30 · see citing works
Renal Artery Stenosis—When To Screen, What To Stent?
Jennings, C. G., Houston, J. G., Severn, A., Bell, S., Mackenzie, I. S., & MacDonald, T. M. (2014) · Current Atherosclerosis Reports · doi:10.1007/s11883-014-0416-2 · Cited by 29 · see citing works
Piechocki, M., Przewłocki, T., Pieniążek, P., Trystuła, M., Podolec, J., & Kabłak-Ziembicka, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13051508 · Cited by 26 · see citing works
Textor, S. C., & McKusick, M. A. (2016) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000202 · Cited by 26 · see citing works
Timing and Selection for Renal Revascularization in an Era of Negative Trials: What to Do?
Textor, S. C., McKusick, M. A., Misra, S., & Glockner, J. F. (2009) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2009.10.001 · Cited by 25 · see citing works
Cost-effectiveness of Enzyme Replacement Therapy for Fabry Disease
Rombach, S. M., Dijkgraaf, M. G. W., Linthorst, G. E., & Hollak, C. E. M. (2012) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2011.11.141 · Cited by 25 · see citing works
Pickering Syndrome: An Overlooked Renovascular Cause of Recurrent Heart Failure
Sanga, V., Bertoli, E., Crimì, F., Barbiero, G., Battistel, M., Seccia, T. M., & Rossi, G. P. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.030474 · Cited by 24 · see citing works
Update on intervention versus medical therapy for atherosclerotic renal artery stenosis
Mousa, A. Y., AbuRahma, A. F., Bozzay, J. D., Broce, M., & Bates, M. C. (2015) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2014.09.072 · Cited by 24 · see citing works
Ritchie, J. P., Green, D., Alderson, H. V., Chrysochou, C., Vassallo, D., Sinha, S., & Kalra, P. A. (2015) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2015.12.002 · Cited by 24 · see citing works
Tendera, M., Aboyans, V., Bartelink, M.-L. E. L., Baumgärtner, I., Clement, D. L., Collet, J., Cremonesi, A., Carlo, M. D., Erbel, R. M., Fowkes, F. G. R., et al. (2012) · Revista Española de Cardiología · doi:10.1016/j.recesp.2011.11.007 · Cited by 22 · see citing works
Emerging Paradigms in Chronic Kidney Ischemia
Eirin, A., Textor, S. C., & Lerman, L. O. (2018) · Hypertension · doi:10.1161/hypertensionaha.118.11082 · Cited by 22 · see citing works
Chazova, I. E., Михайловна, Ч. Н., Blinova, N. V., Владимировна, А. А., Alekseeva, T. A., Ambatiello, L. G., Balanova, Y. А., Bragina, A. E., Danilov, N. M., Drapkina, O. M., et al. (2024) · Systemic Hypertension · doi:10.38109/2075-082x-2024-4-5-109 · Cited by 23 · see citing works
Resistant Hypertension Updated Guidelines
Chernova, I., & Krishnan, N. (2019) · Current Cardiology Reports · doi:10.1007/s11886-019-1209-6 · Cited by 21 · see citing works
Management of Renal Artery Stenosis: 2010
Colyer, W. R., & Cooper, C. J. (2011) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-011-0111-3 · Cited by 18 · see citing works
Kidney Intrinsic Mechanisms as Novel Targets in Renovascular Hypertension
Eirin, A., Chade, A., & Lerman, L. O. (2023) · Hypertension · doi:10.1161/hypertensionaha.123.21362 · Cited by 17 · see citing works
Clinical Problems in Renovascular Disease and the Role of Nuclear Medicine
Prigent, A., & Chaumet‐Riffaud, P. (2014) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2013.10.006 · Cited by 17 · see citing works
Prise en charge actuelle de l’hypertension artérielle
Steichen, O., & Plouin, P. (2013) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2013.06.013 · Cited by 15 · see citing works
Where now in the management of renal artery stenosis? Implications of the ASTRAL and CORAL trials
Ritchie, J. P., Alderson, H. V., & Kalra, P. A. (2014) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000059 · Cited by 15 · see citing works
Optimal Medical Management in Patients with Renovascular Hypertension
Balafa, O. C., Kalaitzidis, R., & Siamopoulos, K. C. (2013) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-013-0011-x · Cited by 15 · see citing works
Seddon, M. D., & Saw, J. (2011) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2010.12.038 · Cited by 15 · see citing works
Österreichischer Blutdruckkonsens 2019
Hypertensiologie, Ö. G. F., Weber, T., Atherosklerosegesellschaft, Ö., Gesellschaft, Ö. D., Angiologie, Ö. G. F. I., Nephrologie, Ö. G. F., Gesellschaft, Ö. K., Neurologie, Ö. G. F., Schlaganfall-Gesellschaft, Ö., Allgemeinmedizin, Ö. G. F., et al. (2019) · Wiener klinische Wochenschrift · doi:10.1007/s00508-019-01565-0 · Cited by 15 · see citing works
Böhlke, M., & Barcellos, F. C. (2015) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2014.11.026 · Cited by 14 · see citing works
Long-term safety and efficacy of renin–angiotensin blockade in atherosclerotic renal artery stenosis
Sofroniadou, S., Kassimatis, T. I., Srirajaskanthan, R., REIDY, J. F., & Goldsmith, D. J. A. (2011) · International Urology and Nephrology · doi:10.1007/s11255-011-0091-y · Cited by 12 · see citing works
Ritchie, J. P., Green, D., Chrysochou, C., Hegarty, J., Handley, K., Ives, N. J., Wheatley, K., Houston, J. G., Wright, J. R., Neyses, L., et al. (2016) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfw107 · Cited by 12 · see citing works
Novel therapeutic strategies for renovascular disease
Eirin, A., Textor, S. C., & Lerman, L. O. (2019) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000513 · Cited by 11 · see citing works
Textor, S. C. (2013) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0b013e328363ffe0 · Cited by 11 · see citing works
Effects of chronic sympatho-inhibition on renal excretory function in renovascular hypertension
Burke, S. L., Evans, R. G., & Head, G. A. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283449529 · Cited by 11 · see citing works
Revascularization in Renal Artery Stenosis
Foy, A., Ruggiero, N. J., & Filippone, E. J. (2012) · Cardiology in Review · doi:10.1097/crd.0b013e31824a72e9 · Cited by 10 · see citing works
Cequier, A. R., Carrascosa, C., Díez‐Tejedor, E., Goicoechea, M., González-García, A., Quiles, J., Ruiz-Salmeron, R. J., Riambau, V., Gómez, Á. M. A., Anguita, M. P., et al. (2012) · Revista Española de Cardiología · doi:10.1016/j.recesp.2011.12.002 · Cited by 10 · see citing works
Khan, Z., Tolia, S. Y., Sanam, K., Gholkar, G., Zughaib, M. T., Naik, S., & Zughaib, M. (2018) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2018.06.008 · Cited by 10 · see citing works
Renal Artery Stenosis: Medical Versus Interventional Therapy
Textor, S. C., & Lerman, L. O. (2013) · Current Cardiology Reports · doi:10.1007/s11886-013-0409-8 · Cited by 9 · see citing works
Chapter 13. Secondary hypertension
(2014) · Hypertension Research · doi:10.1038/hr.2014.16 · Cited by 9 · see citing works
Kurzfassung der S2k-Leitlinie Erkrankungen der Nierenarterie
Oberhuber, A., Hupp, T., Richter, G. M., Nitzsche, E. U., Radermacher, J., Rump, L. C., & Vonend, O. (2019) · Gefässchirurgie · doi:10.1007/s00772-019-0520-2 · Cited by 8 · see citing works
Evaluations of secondary hypertension and laboratory data in the elderly population
Chen, Z., Chan, C., Lin, C.-H., Lee, C.-F., Lo, H.-Y., Huang, Y., Yeh, C., Chen, M. Y., Lai, T., Huang, K., et al. (2024) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2024.07.020 · Cited by 8 · see citing works
Geavlete, O. D., Calin, C., Croitoru, M., Lupescu, I., & Ginghină, C. (2012) · Europe PMC (PubMed Central) · Cited by 7 · see citing works
Atherosclerotic renal artery stenosis and revascularization
Choi, S. S. (2014) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.2014.977258 · Cited by 7 · see citing works
Endovascular Versus Medical Therapy for Atherosclerotic Renovascular Disease
Yu, M. S., Folt, D. A., Drummond, C. A., Haller, S. T., Cooper, E. L., Brewster, P. S., Evans, K. L., & Cooper, C. J. (2014) · Current Atherosclerosis Reports · doi:10.1007/s11883-014-0459-4 · Cited by 7 · see citing works
Arterial stiffness in atherosclerotic renovascular hypertension
Fodor, L., Premužić, V., Ivković, V., Perkov, D., Laganović, M., Vrkić, T. Ž., Dika, Ž., Živko, M., & Jelaković, B. (2014) · Journal of Hypertension · doi:10.1097/hjh.0000000000000324 · Cited by 7 · see citing works
Folt, D. A., Evans, K. L., Brahmandam, S., He, W., Brewster, P. S., Yu, S., Murphy, T. P., Cutlip, D. E., Dworkin, L. D., Jamerson, K., et al. (2015) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2015.03.007 · Cited by 7 · see citing works
Self-citationMazza, A., Ravenni, R., Armigliato, M., Rossetti, C., Schiavon, L., Fiorini, F., Rigatelli, G., Ramazzina, E., & Casiglia, E. (2016) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-015-0128-x · Cited by 7 · see citing works
Management of renovascular hypertension
Textor, S. C. (2020) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000790 · Cited by 7 · see citing works
Dysplasie des artères rénales chez l’adulte
Amar, L., Azarine, A., Carreira, E., Vidal-Trécan, T., & Plouin, P. (2011) · La Presse Médicale · doi:10.1016/j.lpm.2011.02.033 · Cited by 6 · see citing works
Revascularization as a treatment to improve renal function
Kalra, P. A., Alderson, H. V., & Ritchie, J. P. (2014) · International Journal of Nephrology and Renovascular Disease · doi:10.2147/ijnrd.s35633 · Cited by 6 · see citing works
Ibuki, C., Kawamata, H., Seino, Y., & Mizuno, K. (2010) · Internal Medicine · doi:10.2169/internalmedicine.49.4055 · Cited by 5 · see citing works
Atherosclerotic Renovascular Disease: Epidemiology and Clinical Manifestations
Ritchie, J. P., & Kalra, P. A. (2014) · Springer eBooks · doi:10.1007/978-1-4471-2810-6_1 · Cited by 5 · see citing works
Renovascular Hypertension and Ischemic Renal Disease
Textor, S. C., & Greco, B. (2010) · Elsevier eBooks · doi:10.1016/b978-0-323-05876-6.00037-x · Cited by 5 · see citing works
Prise en charge de la sténose athéromateuse d’artère rénale en 2016
Fournier, T., Sens, F., Rouvière, O., Millon, A., & Juillard, L. (2016) · Néphrologie & Thérapeutique · doi:10.1016/j.nephro.2016.07.450 · Cited by 5 · see citing works
Renovascular Hypertension and Ischemic Nephropathy
Textor, S. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-42973-3.00013-5 · Cited by 5 · see citing works
What's new in hypertension 2008?
Mann, J. F. E. (2008) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfn642 · Cited by 5 · see citing works
Diagnosis and treatment of resistant hypertension
Waeber, B., Volpe, M., Ruilope, L. M., & Schmieder, R. E. (2013) · Blood Pressure · doi:10.3109/08037051.2013.854946 · Cited by 4 · see citing works
Devanaboyina, M., Shastri, P., Thompson, N., Tsai, L., Bajrami, S., Devarasetty, P. P., Brewster, P. S., Dworkin, L. D., Cooper, C. J., & Gupta, R. (2022) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2022.10.001 · Cited by 4 · see citing works
Secondary hypertension: evaluation and management
Tandan, N., Lavie, C. J., Stewart, M. H., Milani, R. V., & Ventura, H. O. (2023) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000001059 · Cited by 5 · see citing works
Renovascular Hypertension and Ischemic Nephropathy
Textor, S. C., & Taler, S. J. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-88369-6.00013-x · Cited by 4 · see citing works
Current views on the management of atherosclerotic renovascular disease
Ritchie, J. P., Green, D., & Kalra, P. A. (2012) · Annals of Medicine · doi:10.3109/07853890.2012.687834 · Cited by 4 · see citing works
Atherosclerotic Renovascular Hypertension : Lessons from Recent Clinical Studies
Chung, W., & Kim, S. (2010) · Electrolytes & Blood Pressure · doi:10.5049/ebp.2010.8.2.87 · Cited by 3 · see citing works
When Revascularization May Be Appropriate in Atherosclerotic Renal Artery Stenosis
Zarrella, M. N., Wynne, K., Smith, P., Duraiyarasan, S., & Elbey, M. A. (2024) · Cureus · doi:10.7759/cureus.64854 · Cited by 3 · see citing works
Medical therapy for renal artery stenosis
Colyer, W. R., & Cooper, C. J. (2011) · Clinical Investigation · doi:10.4155/cli.11.99 · Cited by 3 · see citing works
Use of Renin-Angiotensin System Blockade in Patients with Renal Artery Stenosis
Cohen, J. B., & Townsend, R. R. (2014) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.04240414 · Cited by 3 · see citing works
Pathologie des artères rénales
Rafat, C., Amar, L., Steichen, O., & Plouin, P. (2012) · EMC - Angéiologie · doi:10.1016/s1290-0176(12)56547-6 · Cited by 2 · see citing works
Михайловна, Ч. Н. (2022) · Systemic Hypertension · doi:10.38109/2075-082x-2022-1-49-54 · Cited by 2 · see citing works
Cequier, A. R., Carrascosa, C., Díez‐Tejedor, E., Goicoechea, M., González-García, A., Quiles, J., Ruiz-Salmeron, R. J., Riambau, V., Gómez, Á. M. A., Anguita, M. P., et al. (2012) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2011.12.003 · Cited by 2 · see citing works
Jarraya, F., Pruijm, M. T., Wuerzner, G., & Burnier, M. (2013) · Current Hypertension Reports · doi:10.1007/s11906-013-0376-x · Cited by 2 · see citing works
Macrovascular Involvement in Diabetes: Renal Artery Stenosis
van den Born, B. H., & Amraoui, F. (2018) · Springer eBooks · doi:10.1007/978-3-319-93521-8_21 · Cited by 2 · see citing works
Valsartan Effective for Malignant Hypertension after Aortic Dissection with Renal Artery Involvement
Michaud, C. J., & Trethowan, B. A. (2018) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.2100 · Cited by 2 · see citing works
Kher, V., & Nandwani, A. (2016) · Hypertension Journal · doi:10.5005/jp-journals-10043-0037 · Cited by 2 · see citing works
Dilatation des sténoses athéroscléreuses des artères rénales : la fin de l’histoire ?
Plouin, P., Amar, L., & Azizi, M. (2014) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2014.05.006 · Cited by 2 · see citing works
Medical therapy is best for atherosclerotic renal artery stenosis: Arguments for
Annigeri, R. A. (2011) · Indian Journal of Nephrology · doi:10.4103/0971-4065.91177 · Cited by 1 · see citing works
- Authors
- Hackam, D. G., Duong-Hua, M. L., Mamdani, M., Li, P., Tobe, S. W., Spence, J. D., & Garg, A. X.
- Affiliations
- Western University (CA)
- Institute for Clinical Evaluative Sciences (CA)
- University of Toronto (CA)
- Corresponding author
- Hackam, Daniel G.
- Venue
- American Heart Journal
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 156
- Issue
- 3
- Pages
- 549-555
- ISSN
- 0002-8703 (ISSN-L)
- OpenAlex
- W1976834810
- Cited by
- 143
- References
- 57
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 8 · 2023: 7 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 7 · 2018: 12 · 2017: 6 · 2016: 12 · 2015: 8 · 2014: 16 · 2013: 9 · 2012: 13
- FWCI
- 7.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Renin-Angiotensin System Studies
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Renal and Vascular Pathologies
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Keywords
- renovascular disease, ACE inhibitors, angiotensin receptor blockers, renin-angiotensin system blockade, cardiovascular outcomes, acute kidney injury, congestive heart failure, dialysis initiation, mortality, stroke, myocardial infarction, renal function monitoring
- MeSH terms
- Aged, Aged, 80 and over, Angiotensins, Cardiovascular Diseases, Female, Follow-Up Studies, Heart Failure, Renal Dialysis, Hormone Antagonists, Hospitalization, Humans, Kidney, Kidney Diseases, Male, Myocardial Infarction, Renin-Angiotensin System, Vascular Diseases, Cohort Studies, Proportional Hazards Models, Risk Assessment, Stroke, Acute Kidney Injury
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
