A review of dyspnea in acute heart failure syndromes
Abstract
In acute heart failure syndrome (AHFS), dyspnea is one of the most common but least understood presenting symptoms for hospitalization. For this reason, dyspnea relief is increasingly becoming a focus in the development of therapies for the treatment of AHFS, and currently stands as an acceptable primary end point for regulatory approval by governmental agencies. This raises the question of how best to measure such a subjective symptom. In this review, we will describe the basis for dyspnea, provide a detailed description of the strengths and weaknesses of the current best tools used to measure it, and describe future directions for future development of dyspnea measurement in AHFS.
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Many dyspnoea questionnaires have been validated for reproducibility with some correlating to prognosis, but in general they lack sensitivity to acute changes in dyspnoea or specificity to CHF, with some too long or under copyright to be practical for routine clinical use.
“While many of these questionnaires have been validated for reproducibility with some correlating to prognosis, in general, they lack sensitivity to acute changes in dyspnoea or specificity to CHF with some too long or under copyright to be practical for routine clinical use. 51”
From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [51]
There is no agreed questionnaire for dyspnoea in CHF.
“There is no agreed questionnaire for dyspnoea in CHF, 51”
From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [51]
Breathlessness can be episodic or continuous, ranging from an uncomfortable awareness of breathing to a feeling of suffocation or breathlessness.
“Breathlessness can be episodic or continuous, ranging from an uncomfortable awareness of breathing to a feeling of suffocation or breathlessness. 1 , 10 , 51”
From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [51]
Cites
Jaeschke, R., Singer, J., & Guyatt, G. H. (1989) · Controlled Clinical Trials · doi:10.1016/0197-2456(89)90005-6 · Cited by 4,982 · see citing works
Dyspnea: Mechanisms, Assessment, and Management: A Consensus Statement
(1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.159.1.ats898 · Cited by 1,052 · see citing works
Publication Committee for the VMAC Investigators. (2002) · ACC Current Journal Review · doi:10.1016/s1062-1458(02)00795-x · Cited by 982 · see citing works
Dyspnea Mechanisms, Assessment and Management: A Consensus Statement
Editorial, A. (2005) · PULMONOLOGIYA · doi:10.18093/0869-0189-2005-0-2-9-36 · Cited by 859 · see citing works
Gheorghiade, M., Zannad, F. M., Sopko, G. S., Klein, L., Piña, I. L., Konstam, M. A., Massie, B. M., Roland, E., Targum, S. L., Collins, S. P., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.590091 · Cited by 788 · see citing works
Acute Hemodynamic and Clinical Effects of Levosimendan in Patients With Severe Heart Failure
Slawsky, M., Colucci, W. S., Gottlieb, S. S., Greenberg, B., Haeusslein, E. A., Hare, J. M., Hutchins, S. W., Leier, C. V., LeJemtel, T. H., Loh, E., et al. (2000) · Circulation · doi:10.1161/01.cir.102.18.2222 · Cited by 476 · see citing works
Manning, H. L., & Schwartzstein, R. M. (1995) · New England Journal of Medicine · doi:10.1056/nejm199512073332307 · Cited by 472 · see citing works
Hajiro, T., Nishimura, K., Tsukino, M., Ikeda, A., Koyama, H., & Izumi, T. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.4.9802091 · Cited by 254 · see citing works
Minimal important difference of the transition dyspnoea index in a multinational clinical trial
Witek, T. J., & Mahler, D. A. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00068503a · Cited by 225 · see citing works
Mebazaa, A., Pang, P. S., Tavares, M., Collins, S. P., Storrow, A. B., Laribi, S., André, S., Courtney, D. M., Hasa, J., Špinar, J., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp458 · Cited by 184 · see citing works
McMurray, J. J. V., & Stewart, S. (2003) · European Heart Journal Supplements · doi:10.1016/s1520-765x(03)80002-0 · Cited by 160 · see citing works
Hernandez, A. F., O’Connor, C. M., Starling, R. C., Reist, C. J., Armstrong, P. W., Dickstein, K., Lorenz, T. J., Gibler, W. B., Hasselblad, V., Michel Komajda, N., et al. (2008) · American Heart Journal · doi:10.1016/j.ahj.2008.07.031 · Cited by 148 · see citing works
Pang, P. S., Cleland, J. G. F., Teerlink, J. R., Collins, S. P., Lindsell, C. J., Sopko, G. S., Peacock, W. F., Fonarow, G. C., Aldeen, A. Z., Kirk, J., et al. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn048 · Cited by 136 · see citing works
Torre‐Amione, G., Young, J. B., Colucci, W. S., Lewis, B. S., Pratt, C. M., Cotter, G., Stangl, K., Elkayam, U., Teerlink, J. R., Frey, A., et al. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00556-4 · Cited by 118 · see citing works
Minimal Clinically Important Difference for the UCSD Shortness of Breath Questionnaire
Kupferberg, D. H., Kaplan, R. M., Slymen, D. J., & Ries, A. L. (2005) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-200511000-00011 · Cited by 110 · see citing works
End Points for Clinical Trials in Acute Heart Failure Syndromes
Allen, L. A., Hernandez, A. F., O’Connor, C. M., & Felker, G. M. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.12.079 · Cited by 103 · see citing works
Clinically Meaningful Changes in Quantitative Measures of Asthma Severity
Karras, D. J., Sammon, M., Terregino, C. A., Lopez, B. L., Griswold, S., & Arnold, G. K. (2000) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2000.tb02231.x · Cited by 85 · see citing works
McMurray, J. J. V., & Stewart, S. (2002) · European Heart Journal Supplements · doi:10.1093/ehjsupp/4.suppl_d.d50 · Cited by 81 · see citing works
Dyspnea as an end point in clinical trials of therapies for acute decompensated heart failure
Teerlink, J. R. (2003) · American Heart Journal · doi:10.1067/mhj.2003.151 · Cited by 68 · see citing works
Ander, D. S., Aisiku, I. P., Ratcliff, J. J., Todd, K. H., & Gotsch, K. (2004) · Congestive Heart Failure · doi:10.1111/j.1527-5299.2004.03475.x · Cited by 66 · see citing works
Clinical Utility of Measures of Breathlessness
Cullen, D. L., & Rodak, B. (2002) · Respiratory Care · doi:10.1177/002013240204700902 · Cited by 54 · see citing works
Allen, L. A., Metra, M., Milo‐Cotter, O., Filippatos, G. S., Reisin, L., Bensimhon, D., Gronda, E., Colombo, P. C., Felker, G. M., Cas, L. D., et al. (2008) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2008.07.188 · Cited by 44 · see citing works
Parshall, M. B., Welsh, J. D., Brockopp, D. Y., Heiser, R. M., Schooler, M. P., & Cassidy, K. B. (2001) · Heart & Lung · doi:10.1067/mhl.2001.112499 · Cited by 34 · see citing works
Determining the cause of dyspnoea: linguistic and biological descriptors
Ambrosino, N., & Serradori, M. (2006) · Chronic Respiratory Disease · doi:10.1191/1479972306cd110ra · Cited by 34 · see citing works
Boni, E., Bezzi, M., Carminati, L., Corda, L., Grassi, V., & Tantucci, C. (2005) · CHEST Journal · doi:10.1378/chest.128.2.1050 · Cited by 23 · see citing works
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O'Connor, C. M., Starling, R. C., Hernandez, A. F., Armstrong, P. W., Dickstein, K., Hasselblad, V., Heizer, G., Michel Komajda, N., Massie, B. M., McMurray, J. J. V., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1100171 · Cited by 1,249 · see citing works
Symptom burden in heart failure: assessment, impact on outcomes, and management
Alpert, C. M., Smith, M. A., Hummel, S. L., & Hummel, E. K. (2017) · Heart Failure Reviews · doi:10.1007/s10741-016-9581-4 · Cited by 304 · see citing works
Acute Treatment With Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure
Teerlink, J. R., Felker, G. M., McMurray, J. J. V., Ponikowski, P. P., Metra, M., Filippatos, G. S., Ezekowitz, J. A., Dickstein, K., Cleland, J. G. F., Kim, J. B., et al. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.01.031 · Cited by 235 · see citing works
Zannad, F., Garcia, A. A., Anker, S. D., Armstrong, P. W., Calvo, G., Cleland, J. G. F., Cohn, J. N., Dickstein, K., Domanski, M. J., Ekman, I., et al. (2013) · European Journal of Heart Failure · doi:10.1093/eurjhf/hft095 · Cited by 231 · see citing works
Kociol, R. D., McNulty, S. E., Hernandez, A. F., Lee, K. L., Redfield, M. M., Tracy, R. P., D, E. B. M., O’Connor, C. M., & Felker, G. M. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.112.969246 · Cited by 185 · see citing works
The patient perspective: Quality of life in advanced heart failure with frequent hospitalisations
Nieminen, M. S., Dickstein, K., Fonseca, C., Serrano, J. M., Parissis, J., Fedele, F., Wikström, G., Agostoni, P., Atar, S., Baholli, L., et al. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.04.235 · Cited by 164 · see citing works
Quality of Life and Left Ventricular Assist Device Support
MacIver, J., & Ross, H. J. (2012) · Circulation · doi:10.1161/circulationaha.111.040279 · Cited by 142 · see citing works
Breathlessness and the brain: the role of expectation
Marlow, L. L., Faull, O. K., Finnegan, S. L., & Pattinson, K. T. S. (2019) · Current Opinion in Supportive & Palliative Care · doi:10.1097/spc.0000000000000441 · Cited by 77 · see citing works
Prioritizing symptom management in the treatment of chronic heart failure
Koshy, A. O., Gallivan, E. R., McGinlay, M., Straw, S., Drozd, M., Toms, A. G., Gierula, J., Cubbon, R. M., Kearney, M. T., & Witte, K. K. (2020) · ESC Heart Failure · doi:10.1002/ehf2.12875 · Cited by 66 · see citing works
Givertz, M. M., Teerlink, J. R., Albert, N. M., Canary, C. A. W., Collins, S. P., Colvin, M. M., Ezekowitz, J. A., Fang, J. C.-T., Hernandez, A. F., Katz, S. D., et al. (2013) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2013.04.002 · Cited by 61 · see citing works
Assessing quality-of-life outcomes in cardiovascular clinical research
Mark, D. (2016) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.10 · Cited by 58 · see citing works
COPD and heart failure: differential diagnosis and comorbidity
Güder, G., & Störk, S. (2019) · Herz · doi:10.1007/s00059-019-4814-7 · Cited by 57 · see citing works
Relation of Dyspnea Severity on Admission for Acute Heart Failure With Outcomes and Costs
Mentz, R. J., Mi, X., Sharma, P. P., Qualls, L. G., DeVore, A. D., Johnson, K. W., Fonarow, G. C., Curtis, L. H., & Hernandez, A. F. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.09.048 · Cited by 53 · see citing works
Failing the Failing Heart: A Review of Palliative Care in Heart Failure
Shah, A. B., Morrissey, R. P., Baraghoush, A., Bharadwaj, P., Phan, A., Hamilton, M. A., KOBASHIGAWA, J. A., & Schwarz, E. R. (2013) · Reviews in Cardiovascular Medicine · doi:10.3909/ricm0635 · Cited by 47 · see citing works
Recognizing Hospitalized Heart Failure as an Entity and Developing New Therapies to Improve Outcomes
Gheorghiade, M., Shah, A. N., Vaduganathan, M., Butler, J., Bonow, R. O., Rosano, G. M. C., Taylor, S., Kupfer, S., Misselwitz, F., Sharma, A. N., et al. (2013) · Heart Failure Clinics · doi:10.1016/j.hfc.2013.05.002 · Cited by 46 · see citing works
Mentz, R. J., Hernandez, A. F., Stebbins, A., Ezekowitz, J. A., Felker, G. M., Heizer, G., Atar, D., Teerlink, J. R., Califf, R. M., Massie, B. M., et al. (2012) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfs188 · Cited by 45 · see citing works
Assessment of Dyspnea in Acute Decompensated Heart Failure
Ezekowitz, J. A., Hernandez, A. F., O’Connor, C. M., Starling, R. C., Proulx, G., Weiss, M. H., Bakal, J. A., Califf, R. M., McMurray, J. J. V., & Armstrong, P. W. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.11.061 · Cited by 43 · see citing works
Greene, S. J., Shah, A. N., Butler, J., Ambrosy, A. P., Anker, S. D., Chioncel, O., Collins, S. P., Dinh, W., Dunnmon, P. M., Fonarow, G. C., et al. (2014) · American Heart Journal · doi:10.1016/j.ahj.2014.05.009 · Cited by 35 · see citing works
Llorens, P., Miró, Ò., Herrero, P., Martín‐Sánchez, F. J., Jacob, J., Valero, A., Alonso, H., Pérez‐Durá, M. J., Noval, A., Gil-Román, J. J., et al. (2013) · Emergency Medicine Journal · doi:10.1136/emermed-2013-202526 · Cited by 36 · see citing works
Hemodynamic Determinants of Dyspnea Improvement in Acute Decompensated Heart Failure
Solomonica, A., Burger, A. J., & Aronson, D. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.112.970335 · Cited by 36 · see citing works
Gerlach, Y., Williams, M., & Coates, A. M. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.49 · Cited by 36 · see citing works
Learning from recent trials and shaping the future of acute heart failure trials
Mentz, R. J., Felker, G. M., Ahmad, T., Peacock, W. F., Pitt, B., Fiuzat, M., Maggioni, A. P., Gheorghiade, M., Ando, Y., Pocock, S., et al. (2013) · American Heart Journal · doi:10.1016/j.ahj.2013.08.001 · Cited by 32 · see citing works
Pang, P. S., Collins, S. P., Zachrison, K. S., Andrei, A., Storrow, A. B., Hollander, J. E., Tavares, M., Špinar, J., Macarie, C., Raev, D. H., et al. (2014) · Academic Emergency Medicine · doi:10.1111/acem.12390 · Cited by 32 · see citing works
Management of Moderate-to-Severe Dyspnea in Hospitalized Patients Receiving Palliative Care
Gomutbutra, P., O’Riordan, D. L., & Pantilat, S. Z. (2012) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2012.05.004 · Cited by 29 · see citing works
Quality of life for patients supported on a left ventricular assist device
MacIver, J., Rao, V., & Ross, H. J. (2011) · Expert Review of Medical Devices · doi:10.1586/erd.11.9 · Cited by 28 · see citing works
Effect of experimental modulation of mood on perception of exertional dyspnea in healthy subjects
Sharma, P. K., Morris, N. R., & Adams, L. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00122.2015 · Cited by 21 · see citing works
Validation of a three-factor measurement model of dyspnea in hospitalized adults with heart failure
Parshall, M. B., Carle, A. C., Ice, U. V., Taylor, R. A., & Powers, J. (2011) · Heart & Lung · doi:10.1016/j.hrtlng.2011.05.003 · Cited by 19 · see citing works
Andersson, H., Ullgren, A., Holmberg, M., Karlsson, T., Herlitz, J. D., & Sundström, B. W. (2017) · International Emergency Nursing · doi:10.1016/j.ienj.2016.12.001 · Cited by 18 · see citing works
Sokolska, J. M., Sokolski, M., Zymliński, R., Biegus, J., Siwołowski, P., Nawrocka‐Millward, S., Jankowska, E. A., Todd, J., Banasiak, W., & Ponikowski, P. P. (2018) · ESC Heart Failure · doi:10.1002/ehf2.12371 · Cited by 18 · see citing works
Renal Sympathetic Denervation for the Treatment of Refractory Hypertension
Leong, K. T. G., Walton, A., & Krum, H. (2014) · Annual Review of Medicine · doi:10.1146/annurev-med-051812-145353 · Cited by 15 · see citing works
Beyond dyspnoea as an endpoint in acute heart failure trials
Gheorghiade, M., & Ruschitzka, F. T. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr044 · Cited by 15 · see citing works
The Coexistence of Chronic Obstructive Pulmonary Disease and Heart Failure
Khalid, K., Padda, J., Komissarov, A., Colaco, L. B., Padda, S., Khan, A. S., Campos, V. Y. M., & Jean-Charles, G. (2021) · Cureus · doi:10.7759/cureus.17387 · Cited by 14 · see citing works
Association of types of dyspnea including ‘bendopnea’ with cardiopulmonary disease in primary care
Martínez, D., Rosa, M. L. G., Jorge, A. J. L., Martins, W. D. A., Mesquita, E. T., Freire, M. D. C., Correia, D. M. D. S., & Kang, H. C. (2017) · Revista Portuguesa de Cardiologia (English Edition) · doi:10.1016/j.repce.2016.08.006 · Cited by 14 · see citing works
Williams, M. (2011) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0b013e328345d4a1 · Cited by 13 · see citing works
Martínez, D., Rosa, M. L. G., Jorge, A. J. L., Martins, W. D. A., Mesquita, E. T., Freire, M. D. C., Correia, D. M. D. S., & Kang, H. C. (2017) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2016.08.007 · Cited by 13 · see citing works
Zhang, X., Zhao, C., Zhang, H., Liu, W., Zhang, J., Chen, Z., You, L., Wu, Y., Zhou, K., Zhang, L., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.728772 · Cited by 12 · see citing works
Adi, O., Via, G., Salleh, S. H., Chuan, T. W., Rahman, J. A., Muhamad, N. A. N., Atan, R., & Yunos, N. M. (2021) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2021.06.031 · Cited by 12 · see citing works
Evaluation of a provocative dyspnea severity score in acute heart failure
AbouEzzeddine, O. F., Lala, A., Khazanie, P., Shah, R. V., Ho, J. E., Chen, H. H., Pang, P. S., McNulty, S. E., Anstrom, K. J., Hernandez, A. F., et al. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.10.009 · Cited by 12 · see citing works
Tolvaptan in Acute Heart Failure
Starling, R. C., & Young, J. B. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.09.005 · Cited by 11 · see citing works
Benefits of tolvaptan on early dyspnea relief in patients with acute heart failure: A meta‐analysis
Shang, W., Zhang, Y., & Han, D. H. (2022) · Clinical Cardiology · doi:10.1002/clc.23889 · Cited by 9 · see citing works
Garus, M., Jura, M., Guzik, M., Zymliński, R., Iwanek, G., Ponikowski, P. P., & Biegus, J. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-075302 · Cited by 7 · see citing works
Pang, P. S., & Zaman, M. (2013) · Current Emergency and Hospital Medicine Reports · doi:10.1007/s40138-013-0011-9 · Cited by 7 · see citing works
Cardiac Myosin Activators for the Treatment of Heart Failure
Starling, R. C. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.01.038 · Cited by 7 · see citing works
Nesiritide in Acute Decompensated Heart Failure
Kramer, D. B. (2011) · New England Journal of Medicine · doi:10.1056/nejmc1109292 · Cited by 7 · see citing works
Cardiorenal Syndrome Clinical Trial End Points
Mentz, R. J., & O’Connor, C. M. (2011) · Heart Failure Clinics · doi:10.1016/j.hfc.2011.06.012 · Cited by 6 · see citing works
The effect of different exercise modalities on dyspnea and leg fatigue in healthy subjects
Sharma, P. K., Morris, N. R., & Adams, L. (2015) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2015.02.001 · Cited by 6 · see citing works
Akpınar, G., & Topaçoğlu, H. (2021) · Journal of Surgery and Medicine · doi:10.28982/josam.900938 · Cited by 4 · see citing works
Heart failure symptoms as predictors of hospital admission, readmission and all-cause mortality
Ali, M., Freeman, S. C., Gray, L. J., Kadam, U. T., & Lawson, C. A. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015206 · Cited by 4 · see citing works
Massie, B. M. (2012) · Goldman's Cecil Medicine · doi:10.1016/b978-1-4377-1604-7.00058-0 · Cited by 4 · see citing works
Leong, K. T. G., & Krum, H. (2013) · Current Cardiology Reports · doi:10.1007/s11886-013-0414-y · Cited by 3 · see citing works
Experimental modulation of mood by acoustic stimulation and its effect on exertional dyspnoea
Sharma, P. K., Hall, L. G., Morris, N. R., Sabapathy, S., & Adams, L. (2019) · Thorax · doi:10.1136/thoraxjnl-2018-212683 · Cited by 3 · see citing works
Acute Decompensated Heart Failure: The Quest to Live Longer and Feel Better
Arnold, J. M. O., & Porepa, L. F. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.01.032 · Cited by 2 · see citing works
Assessment of Dyspnea in Acute Heart Failure Patients with Three Scales in the Emergency Department
GENOĞLU, C. K., Köse, A., Bozkurt, S., Toker, İ., Erdoğan, S., Muşlu, N., & Çelik, A. (2023) · Anatolian Journal of Emergency Medicine · doi:10.54996/anatolianjem.1053506 · Cited by 1 · see citing works
Minamino‐Muta, E., Kato, T., Morimoto, T., Yaku, H., Inuzuka, Y., Tamaki, Y., Ozasa, N., Shiba, M., Yamamoto, E., Yoshikawa, Y., et al. (2026) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcag017 · Cited by 1 · see citing works
What Interventions Are Effective for Managing Dyspnea in Heart Failure?
Goldstein, N. E., & Ascheim, D. D. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-3796-7.00023-9 · Cited by 1 · see citing works
Patterns and predictors of dyspnoea following left ventricular assist device implantation
Faulkner, K. M., Jurgens, C. Y., Denfeld, Q. E., Chien, C., Thompson, J. H., Gelow, J. M., Grady, K. L., & Lee, C. S. (2022) · European Journal of Cardiovascular Nursing · doi:10.1093/eurjcn/zvac007 · Cited by 1 · see citing works
Yorita, A., Tokunaga, Y., Kinoshita, T., Nakakura, A., Oda, H., Imaoka, H., Matsunaga, K., Kakuma, T., Hoshino, T., & Kawayama, T. (2021) · The Kurume Medical Journal · doi:10.2739/kurumemedj.ms6834008 · Cited by 1 · see citing works
What Interventions Are Effective for Managing Dyspnea in Heart Failure?
Avant, L. C., Dionne-Odom, J. N., & Swetz, K. M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-84702-5.00017-8 · Cited by 1 · see citing works
Givertz, M. M., Teerlink, J. R., Albert, N. M., Canary, C. A. W., Collins, S. P., Colvin, M. M., Ezekowitz, J. A., Fang, J. C.-T., Hernandez, A. F., Katz, S. D., et al. (2013)
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Mentz, R. J. (2011)
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Maciver, E. J. (2012) · TSpace (University of Toronto)
Sharma, P. K. (2015) · Griffith Research Online · doi:10.25904/1912/1208
Cotter, G., & Milo, O. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734446227.793556980
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Sivri, F., Koyuncu, İ., Gül, İ., Ardıç, M. L., & İçen, Y. K. (2024) · Harran Üniversitesi Tıp Fakültesi Dergisi · doi:10.35440/hutfd.1578009
- Authors
- West, R. L., Hernandez, A. F., O'Connor, C. M., Starling, R. C., & Califf, R. M.
- Affiliations
- Duke University (US)
- Cleveland Clinic (US)
- Corresponding author
- Hernandez, Adrian F.
- Venue
- American Heart Journal
- Publisher
- Elsevier BV
- Published
- 2010-08
- Volume
- 160
- Issue
- 2
- Pages
- 209-214
- ISSN
- 0002-8703 (ISSN-L)
- OpenAlex
- W2110393231
- Cited by
- 67
- References
- 25
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 5 · 2020: 1 · 2019: 4 · 2018: 1 · 2017: 3 · 2016: 5 · 2015: 5 · 2014: 5 · 2013: 9 · 2012: 12
- FWCI
- 6.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart rate and cardiovascular health
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- dyspnea, acute heart failure, symptom assessment, dyspnea relief, primary endpoint, regulatory approval, subjective symptoms
- MeSH terms
- Dyspnea, Health Status Indicators, Heart Failure, Humans, Pain Measurement, Quality of Life, Severity of Illness Index
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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