The DOI matches its Crossref record; 65 of the 67 references it cites were found in a registry or an index.
Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene
Open accessAbstract
Autism is a genetically complex neurodevelopmental syndrome in which language deficits are a core feature. We describe results from two complimentary approaches used to identify risk variants on chromosome 7 that likely contribute to the etiology of autism. A two-stage association study tested 2758 SNPs across a 10 Mb 7q35 language-related autism QTL in AGRE (Autism Genetic Resource Exchange) trios and found significant association with Contactin Associated Protein-Like 2 (CNTNAP2), a strong a priori candidate. Male-only containing families were identified as primarily responsible for this association signal, consistent with the strong male affection bias in ASD and other language-based disorders. Gene-expression analyses in developing human brain further identified CNTNAP2 as enriched in circuits important for language development. Together, these results provide convergent evidence for involvement of CNTNAP2, a Neurexin family member, in autism, and demonstrate a connection between genetic risk for autism and specific brain structures.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“while the fourth is a homologue of the autism susceptibility gene CNTNAP2 17 .”
From Transcriptomic Analysis of Autistic Brain Reveals Convergent Molecular Pathology (2011) · cites this paper as [17]
Experimental — accuracy not yet measuredIn the citing paper
“Two common polymorphisms in a relatively circumscribed area of CNTNAP2 have been shown to modulate language function in ASD and other conditions [59–61].”
From Genetics of autism spectrum disorders (2011) · cites this paper as [59]
In the citing paper
“Common variants in CNTNAP2 have also been associated with ASD (49–51) and specific-language impairment (52).”
From Individual common variants exert weak effects on the risk for autism spectrum disorders (2012) · cites this paper as [49]
In the citing paper
“To incorporate construct validity for the various genetic mutations identified in small numbers of people with autism (12–21), these mutations have been generated in mice (22, 23).”
From Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism (2012) · cites this paper as [14]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Haploview: analysis and visualization of LD and haplotype maps
Barrett, J. C., Fry, B., Maller, J., & Daly, M. J. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth457 · Cited by 14,551
Smyth, G. K. (2004) · Statistical Applications in Genetics and Molecular Biology · doi:10.2202/1544-6115.1027 · Cited by 11,829
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
Irizarry, R. A. (2003) · Biostatistics · doi:10.1093/biostatistics/4.2.249 · Cited by 10,603
Lord, C., Rutter, M., & Le Couteur, A. (1994) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172145 · Cited by 9,065
A haplotype map of the human genome
The International HapMap Consortium (2005) · Nature · doi:10.1038/nature04226 · Cited by 5,858
Strong association of de novo copy number mutations with autism
Sebat, J., Lakshmi, B., Malhotra, D., Troge, J., Lese-Martin, C., Walsh, T., Yamrom, B., Yoon, S., Krasnitz, A., Kendall, J., et al. (2007) · Science · doi:10.1126/science.1138659 · Cited by 2,795
Self-citationLarge-scale copy number polymorphism in the human genome
Sebat, J., Lakshmi, B., Troge, J., Alexander, J., Young, J., Lundin, P., Månér, S., Massa, H., Walker, M., Chi, M., et al. (2004) · Science · doi:10.1126/science.1098918 · Cited by 2,557
Self-citationLinkage disequilibrium in finite populations
Hill, W. G., & Robertson, A. (1968) · Theoretical and Applied Genetics · doi:10.1007/bf01245622 · Cited by 2,035
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism
Study, P. A. R. I. S., Jamain, S., Quach, H., Betancur, C., Råstam, M., Colineaux, C., Gillberg, I. C., Soderstrom, H., Giros, B., Leboyer, M., et al. (2003) · Nature Genetics · doi:10.1038/ng1136 · Cited by 1,851
Genetic data analysis II: methods for discrete population genetic data
(1996) · Choice Reviews Online · doi:10.5860/choice.34-2150 · Cited by 1,626
Flagged first, then by citations
2 of the 67 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 601–700 of 814
Syndromes and epistemology II: Is autism a polygenic disorder?
Fisch, G. S. (2008) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32438 · Cited by 6
Autism: The Ups and Downs of Neuroligin
Geschwind, D. H. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.022 · Cited by 6
Self-citationDevelopmental Disturbances in Animal Models of Autism Spectrum Disorder
László, K., Bačová, Z., Zelena, D., & Bakoš, J. (2025) · Developmental Neurobiology · doi:10.1002/dneu.22977 · Cited by 5
Graph Node Classification to Predict Autism Risk in Genes
Bandara, D., & Riccardi, K. (2024) · Genes · doi:10.3390/genes15040447 · Cited by 6
Ishido, M., Higashi, K., Mori, H., Ueno, M., & Kurokawa, K. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.115293 · Cited by 5
Genetic Pathways Implicated in Speech and Language
Vernes, S. C., & Fisher, S. E. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8400-4_2 · Cited by 5
Kerosene free Delhi: Safer for children
Sachdeva, S., Gupta, P., Yüksek, S. K., Tezer, H., Ansary, A., Kabra, N. S., Balasubramanian, S., Ramesh, V., Kumar, S. H. C., Ramesh, H. H., et al. (2014) · Indian Pediatrics · doi:10.1007/s13312-014-0512-y · Cited by 5
Autism and epistemology IV: Does autism need a theory of mind?
Fisch, G. S. (2013) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36135 · Cited by 5
Lei, D., Li, S., Banerjee, S., Zhang, H., Li, C., Hou, S., Chen, D., Yan, H., Li, H., peng, H. H., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.12552 · Cited by 4
The Genetic and Epigenetic Basis Involved in the Pathophysiology of ASD: Therapeutic Implications
Carrascosa-Romero, M. C., & de Cabo, C. (2017) · InTech eBooks · doi:10.5772/66854 · Cited by 5
Preliminary evidence for timing abnormalities in the CNTNAP2 knockout rat
Poulin, C. J., & Fox, A. E. (2021) · Behavioural Processes · doi:10.1016/j.beproc.2021.104449 · Cited by 5
Shiota, Y., Hirosawa, T., Yoshimura, Y., Tanaka, S., Hasegawa, C., Iwasaki, S., Sano, M., An, K., Yokoyama, S., & Kikuchi, M. (2022) · Neuropsychopharmacology Reports · doi:10.1002/npr2.12267 · Cited by 5
Vulnerability to Substance Abuse
Uhl, G. R., Drgon, T., Johnson, C., & Liu, Q. (2010) · Springer eBooks · doi:10.1007/978-1-4419-0338-9_10 · Cited by 5
The Genetics of Autism Spectrum Disorders
John, J. M., & Hakonarso, H. (2011) · InTech eBooks · doi:10.5772/10601 · Cited by 5
LoTurco, J. J., & Booker, A. B. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397266-8.00038-7 · Cited by 6
Yoo, H. J., Kim, B., Kim, J.-W., Shin, M., Park, T.-W., Son, J.-W., Chung, U., Park, M., & Kim, S. A. (2016) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000150 · Cited by 5
Genetics and Epigenetics of Autism Spectrum Disorders
Bourgeron, T. (2012) · Research and perspectives in neurosciences · doi:10.1007/978-3-642-27913-3_10 · Cited by 5
Probe into Color Preference in Inpatients with Depressive Disorders
Ran, M., Tan, X., Jiang, G., Chen, X., Yang, H., & Yuan, G. (2017) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20170010 · Cited by 4
AL-Ayadhi, L. Y., Halepoto, D. M., Alhowikan, A. M., Elamin, N. E., & Halepota, A. T. (2024) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s490582 · Cited by 4
Cristina, A., Lúiza, A., & Pereira-Nascimento, P. (2013) · InTech eBooks · doi:10.5772/53106 · Cited by 5
Genetic Overlaps in Mental Retardation, Autism and Schizophrenia
Kooy, R. F., der Aa, N. V., Vandeweyer, G., Reyniers, E., & Rooms, L. (2010) · Monographs in human genetics · doi:10.1159/000287602 · Cited by 4
Genetische Analysen zur Identifizierung molekularer Mechanismen bei Autismus-Spektrum-Störungen
Chiocchetti, A. G., & Klauck, S. M. (2011) · Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie · doi:10.1024/1422-4917/a000096 · Cited by 4
Advances and Challenges in the Genetics of Autism
Campbell, D. B. (2010) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.8.3.foc339 · Cited by 4
The Genetics of Language Acquisition
Mountford, H. S., & Newbury, D. F. (2019) · Routledge eBooks · doi:10.4324/9781315110622-3 · Cited by 4
Jankovic, J. J., Hallett, M., Okun, M. S., Comella, C., Fahn, S., & Goldman, J. G. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-31071-0.00016-0 · Cited by 4
(A)typical language development: genetic and environmental infl uences
Finnegan, E. M. (2015) · Routledge eBooks · doi:10.4324/9780203569245-8 · Cited by 4
Naudhani, S., Ahmad, A., Bazai, F. K., Pervez, M. T., Zafar, A., Shah, S. A., Raheem, N., Baloch, A. H., Mushtaq, M., & Daud, S. (2023) · Molecular Syndromology · doi:10.1159/000529427 · Cited by 5
Arutiunian, V., Santhosh, M., Neuhaus, E., Sullivan, C. A. W., Bernier, R., Bookheimer, S. Y., Dapretto, M., Geschwind, D. H., Jack, A., McPartland, J. C., et al. (2024) · Autism Research · doi:10.1002/aur.3193 · Cited by 4
Self-citationExperimental Approaches for Identifying Schizophrenia Risk Genes
Mantripragada, K. K., Carroll, L. S., & Williams, N. M. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_58 · Cited by 4
Autism and autism spectrum disorders
Geschwind, D. H., & Alarcón, M. (2012) · Cambridge University Press eBooks · doi:10.1017/cbo9781139025997.017 · Cited by 4
Self-citationZhao, Y.-J., Liu, X., Sun, H., Wang, Y., YANG, W., & Ma, H. (2012) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4483 · Cited by 4
Dediu, D. (2013) · The frontiers collection · doi:10.1007/978-3-642-36086-2_7 · Cited by 6
Paleogenomics, hominin interbreeding and language evolution.
Benítez‐Burraco, A., & Barceló-Coblijn, L. (2013) · PubMed · doi:10.4436/jass.91012 · Cited by 4
Biological/Biochemical Features and Molecular Genetics of Specific Language Impairment ( SLI )
Çaylak, E. (2011) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0023688 · Cited by 4
Correction: Defining the Contribution of CNTNAP2 to Autism Susceptibility
Sampath, S., Bhat, S., Gupta, S., O’Connor, A., West, A. B., Arking, D. E., & Chakravarti, A. (2013) · PLoS ONE · doi:10.1371/annotation/b4552fc7-285e-42e8-b126-d498eaf9f73a · Cited by 4
Determining the Linguistic Profile of Children With Rare Genetic Disorders
Espinosa-Mojica, A. A., & Varo, C. V. (2023) · Journal of Speech Language and Hearing Research · doi:10.1044/2023_jslhr-23-00101 · Cited by 3
Zhang, Q.-M., Chen, Y., Xing, Y.-Y., Yang, M., Li, N., Jiang, X., Gao, H., Lu, S., & Yao, J. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03139-1 · Cited by 4
Genes, brain, and behavior: development gone awry in autism?
Lewis, M. J., & Dictenberg, J. B. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05723.x · Cited by 3
Yalcintepe, S. A., Görker, İ., Demır, S., Atlı, E. İ., Atlı, E., Tozkır, H., Süt, N., Ozen, Y., Eker, D., Mail, C., et al. (2021) · Nöro Psikiyatri Arşivi · doi:10.29399/npa.27407 · Cited by 3
Taugher, R. J., Berns, A., Jones, M., Townsend, A., Eagen, A. K., Ferri, S. L., Langbehn, D. R., & Janouschek, H. (2025) · Autism Research · doi:10.1002/aur.70034 · Cited by 3
Spielman, B. P., Bagnall-Moreau, C., Chen, F., Balvuena, C., Cruz, C., Carrión, J., Vo, A., Arazi, A., & Brimberg, L. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03298-1 · Cited by 4
Genes and the long and winding road to cortical construction and cognition
Ross, M. E., & Geschwind, D. H. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.03.004 · Cited by 3
Self-citationKaufman, L., Noor, A., Ayub, M., & John, B. (2011) · InTech eBooks · doi:10.5772/18481 · Cited by 2
Delving into the Genetic Causes of Language Impairment in a Case of Partial Deletion of NRXN1
Benítez‐Burraco, A., Jiménez-Romero, M. S., & Fernández-Urquiza, M. (2022) · Molecular Syndromology · doi:10.1159/000524710 · Cited by 4
Sozańska, N., Krupnik, V., Greb‐Markiewicz, B., Ożyhar, A., & Tarczewska, A. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02265-1 · Cited by 2
Autisme als meerduidig en dynamisch fenomeen
Hens, K., & Goidsenhoven, L. V. (2018) · Algemeen Nederlands Tijdschrift voor Wijsbegeerte · doi:10.5117/antw2018.4.003.hens · Cited by 3
Association of GDNF and CNTNAP2 gene variants with gambling
Das, A., Pagliaroli, L., Vereczkei, A., Kótyuk, E., Langstieh, B., Demetrovics, Z., & Barta, C. (2019) · Journal of Behavioral Addictions · doi:10.1556/2006.8.2019.40 · Cited by 3
Basics of Developmental Disorders of Speech and Language
Zehnhoff‐Dinnesen, A. A., Denk‐Linnert, D., Hegazi, M. A. E.-F., Keilmann, A., Kiese-Himmel, C., Neumann, K., Regele, S., Schönweiler, R., & Seemanová, E. (2019) · European manual of medicine · doi:10.1007/978-3-662-46780-0_9 · Cited by 5
Sokol, D. K., & Lahiri, D. K. (2011) · Springer eBooks · doi:10.1007/978-1-4419-8065-6_6 · Cited by 4
Nickl‐Jockschat, T., & Michel, T. M. (2011) · Der Nervenarzt · Cited by 3
The Genetics of Autism Spectrum Disorder- A Review
Kundu, G. K., & Islam, R. (2021) · Journal of Bangladesh College of Physicians and Surgeons · doi:10.3329/jbcps.v39i3.54166 · Cited by 3
Rice, M. L., & Tager-Flusberg, H. B. (2016) · Innovations in cognitive neuroscience · doi:10.1007/978-1-4614-3846-5_12 · Cited by 3
Evolution and Development of Language
Miller, D. J., & Konopka, G. (2013) · Wiley eBooks · doi:10.1002/9781118707449.ch9 · Cited by 3
Genetic Investigation of Autism-Related Social Communication Deficits
Campbell, D. B. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.14121503 · Cited by 3
Tourette Syndrome: Gene Expression as a Tool to Discover Drug Targets
Liao, I. H., & Sharp, F. R. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.05.007 · Cited by 4
Aleo, S., Milani, D., Pansa, A., Marchisio, P., Guerneri, S., & Silipigni, R. (2020) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.61881 · Cited by 3
Repeated Stress Escalates Aggression and Activity in Fronto‐Limbic Regions in Cntnap2−/− Mice
Hertweck, C. H., Carter, C., McDaniel, S., Llorach, P., Tilton, H. E., Kodali, A., Christoffel, D. J., & Walsh, J. J. (2026) · Genes, Brain and Behavior · doi:10.1111/gbb.70048 · Cited by 2
Synaptic protein mutations in autism
Sauer, A. K., Walsh, J. A., Curran, D., Zohourian, N., Stanton, J. E., Zabetakis, I., Brown, J. A. L., & Grabrucker, A. M. (2026) · Neurobiology of Disease · doi:10.1016/j.nbd.2026.107365 · Cited by 4
Veatch, O. J., Malow, B. A., Pendergast, J. S., Allen, M. J., Leu, R. M., Johnson, C. H., & Elsea, S. H. (2015) · Cited by 2
Developmental Neurobiology of Autism Spectrum Disorders
Rubenstein, J. L. R. (2011) · Oxford University Press eBooks · doi:10.1093/med/9780195371826.003.0035 · Cited by 2
Animal Models of Tic Disorders
Bortolato, M., & Cadeddu, R. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780197543214.003.0017 · Cited by 2
Oh, M., Yoon, N., Kim, S. A., & Yoo, H. J. (2024) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.24.1188 · Cited by 3
Functional Genomic Dissection of Speech and Language Disorders
Vernes, S. C., & Fisher, S. E. (2010) · Advances in neurobiology · doi:10.1007/978-1-4419-7197-5_10 · Cited by 2
Phenotypes and epidemiology of rare neurodevelopmental disorders
van Balkom, I. D. C. (2012) · Cited by 2
Osherovich, L. Z. (2011) · Science-Business eXchange · doi:10.1038/scibx.2011.1137 · Cited by 2
Le langage : une empreinte cognitive
Bourguignon, N. J. (2008) · Cognition représentation langages · doi:10.4000/corela.317 · Cited by 2
Copy number variation in the autism genome
Feuk, L. (2008) · Expert Opinion on Medical Diagnostics · doi:10.1517/17530059.2.4.417 · Cited by 3
[Research advances in candidate genes for autism spectrum disorder].
Yang, Z., & Sun, G. (2016) · PubMed Central · doi:10.7499/j.issn.1008-8830.2016.03.018 · Cited by 2
Genetic Disorders of Cerebral Cortical Development
Mochida, G. H., Poduri, A., & Walsh, C. A. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00121-x · Cited by 2
Fahn, S., Jankovic, J. J., & Hallett, M. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-2369-4.00017-2 · Cited by 2
Singer, H. S., Mink, J. W., Gilbert, D. L., & Jankovic, J. J. (2010) · Elsevier eBooks · doi:10.1016/b978-0-7506-9852-8.00007-2 · Cited by 2
Palatable solution overconsumption in the Cntnap2−/− murine model of autism: a link with oxytocin
Harvey, S., Liyanagamage, D. S. N. K., Pal, T., Klockars, A., Levine, A. S., & Olszewski, P. K. (2024) · Neuroreport · doi:10.1097/wnr.0000000000002089 · Cited by 2
The Molecular Convergence of Birdsong and Speech
Deshpande, M., & Lints, T. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8400-4_6 · Cited by 2
Cell Adhesion Molecules in Synaptopathies
Bourgeron, T. (2009) · Springer eBooks · doi:10.1007/978-0-387-92708-4_6 · Cited by 2
Appreciating autism: stories of my son
Britton, V. C. (2013) · Summit (Simon Fraser University) · Cited by 2
Role of microRNAs in Autism Spectrum Disorder
Sarachana, T., & Hu, V. W. (2013) · Wiley eBooks · doi:10.1002/9781118695999.ch14 · Cited by 2
Autism spectrum disorders : genetic and neurodevelopmental aspects in children with early diagnosis
Eriksson, M. A. (2013) · Figshare · Cited by 2
InDels e CNVs pequenas em pacientes com Transtorno do Espectro Autista
Silva, I. M. W. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.41.2017.tde-29052017-145246 · Cited by 2
Devanna, P., Dediu, D., & Vernes, S. C. (2018) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780198786825.013.37 · Cited by 3
Warrier, V., & Baron‐Cohen, S. (2017) · Wiley eBooks · doi:10.1002/9780470015902.a0021455.pub2 · Cited by 5
Williams, D. M. (2017) · Wiley eBooks · doi:10.1002/9781118554470.ch13 · Cited by 2
Lee, T., & Kim, E. (2024) · Ewha Medical Journal · doi:10.12771/emj.2024.e18 · Cited by 2
Investigating Sequence Variations in CNTNAP2 and SETBP1 Genes in Language Disorders
Turan, B., Göktaş, E., Uzun, N., Selen, A. T. H., Zamanı, A. G., & Yıldırım, M. S. (2024) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.24.1204 · Cited by 1
Facing phonological complexity as an autistic adult: An exploratory study
Manenti, M., Prévost, P., Houy‐Durand, E., Bonnet‐Brilhault, F., & Ferré, S. (2025) · Autism & Developmental Language Impairments · doi:10.1177/23969415251322751 · Cited by 1
Shenoy, P. U., Udupa, H., Ananthakrishnan, A. I., Sunil, P., Sardarni, U. K., Kumar, N., Acharya, A., Byrareddy, S. N., Upadhyai, P., & Das, R. (2026) · Frontiers in Genetics · doi:10.3389/fgene.2025.1696764 · Cited by 1
Analyzing the genetic profile of autistic children and adolescents with minimal verbal abilities
Guerrera, S., Venezia, I., Logrieco, M. G., Casula, L., Capolino, R., Digilio, M. C., Dentici, M. L., Macchiaiolo, M., Casciani, F., Cortellessa, F., et al. (2026) · Frontiers in Genetics · doi:10.3389/fgene.2026.1647481 · Cited by 1
Bazbaz, W., Kartawy, M., Халиулин, И. Г., & Amal, H. (2026) · Molecular Autism · doi:10.1186/s13229-026-00716-1 · Cited by 1
CNTNAP2: isoform- and context-specific functions in neurological disorders and cancer
Ye, Y., Zhu, L., & Wang, D. (2026) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2026.1803486 · Cited by 1
Iglesias-Hernández, P., Palencia, M. M., Ramos, L. S., Tarazona, J. V., Cañas, A., la Vieja, A. D., & Torres-Ruíz, M. (2026) · Environment International · doi:10.1016/j.envint.2026.110434 · Cited by 1
Potential Autoepitope within the Extracellular Region of Contactin-Associated Protein-like 2 in Mice
Obregon, D. F., Zhu, Y., Bailey, A. R., Portis, S. M., Hou, H., Zeng, J., Stock, S. L., Murphy, T. K., Bengtson, M. A., & Tan, J. (2014) · Journal of Advances in Medicine and Medical Research · doi:10.9734/bjmmr/2014/6135 · Cited by 1
Autism genetics: Methodological issues and experimental design
Sacco, R., Lintas, C., & Persico, A. M. (2015) · Science China Life Sciences · doi:10.1007/s11427-012-4315-x · Cited by 1
Autism spectrum disorders in siblings of children with a developmental language disorder
Mouridsen, S. E., & Hauschild, K.-M. (2011) · Logopedics Phoniatrics Vocology · doi:10.3109/14015439.2011.566575 · Cited by 1
Benítez‐Burraco, A. (2012) · Trabajos de Prehistoria · doi:10.3989/tp.2012.12089 · Cited by 2
Chapter 4. Do autism spectrum disorders and specific language impairment have a shared aetiology?
Taylor, L. J., Maybery, M. T., & Whitehouse, A. (2014) · Trends in language acquisition research · doi:10.1075/tilar.11.05tay · Cited by 1
Peñagarikano, O. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800109-7.00012-1 · Cited by 1
White, S. A. (2013) · Studies in language companion series · doi:10.1075/slcs.144.09whi · Cited by 1
Translational Neuroimaging for Drug Discovery and Development in Autism Spectrum Disorders
Badura, L. L., Saxe, M., Risterucci, C., Brammer, M. J., McTighe, S. M., Ring, R. H., & Smith, D. G. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-386945-6.00009-3 · Cited by 1
Autoimmune antibody-associated encephalopathy and dementia syndromes
Fredericks, C. A., & Geschwind, M. D. (2016) · Cambridge University Press eBooks · doi:10.1017/9781139924771.023 · Cited by 1
Enikeeva, R. F., Kazantseva, A. V., Davydova, Y. D., & Хуснутдинова, Э. К. (2020) · RESEARCH RESULTS IN BIOMEDICINE · doi:10.18413/2658-6533-2020-6-1-0-3 · Cited by 1
Identification of Autistic Risk Genes Using Developmental Brain Gene Expression Data
Huang, Z.-A., Huang, Y., You, Z., Zhang, S., Yu, C.-Q., & Huang, W. (2020) · Lecture notes in computer science · doi:10.1007/978-3-030-60802-6_29 · Cited by 1
Metadata
- Authors
- Alarcón, M., Abrahams, B. S., Stone, J. L., Duvall, J. A., Perederiy, J. V., Bomar, J. M., Sebat, J., Wigler, M., Martin, C. L., Ledbetter, D. H., Nelson, S. F., Cantor, R. M., & Geschwind, D. H.
- Affiliations
- University of California, Los Angeles (US)
- Cold Spring Harbor Laboratory (US)
- Emory University (US)
- Corresponding author
- Geschwind, Daniel H.
- ORCID
- Venue
- The American Journal of Human Genetics
- Publisher
- Elsevier BV
- Published
- 2008-01
- Volume
- 82
- Issue
- 1
- Pages
- 150-159
- ISSN
- 0002-9297 (ISSN-L)
- PMC
- PMC2253955
- OpenAlex
- W2126538155
- Cited by
- 818
- References
- 67
- Citations by year
- 2026: 15 · 2025: 12 · 2024: 19 · 2023: 19 · 2022: 26 · 2021: 35 · 2020: 29 · 2019: 28 · 2018: 28 · 2017: 52 · 2016: 43 · 2015: 53 · 2014: 48 · 2013: 69 · 2012: 82
- FWCI
- 44.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- The American Journal of Human Genetics (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory) (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH64547, R01MH064547, R01MH076431)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- CNTNAP2, autism susceptibility, language development, neurexin, genetic linkage, genetic association, trios, brain gene expression, neurodevelopmental disorders
- MeSH terms
- Autistic Disorder, Brain, Child, Chromosomes, Human, Pair 7, Female, Humans, Language Development, Male, Membrane Proteins, Nerve Tissue Proteins, Gene Expression, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
