The DOI matches its Crossref record; 32 of the 36 references it cites were found in a registry or an index.
Population-Based Incidence of Uveal Melanoma in Various Races and Ethnic Groups
Abstract
Purpose To investigate racial/ethnic differences in the development of uveal malignant melanoma in a large population-based study.Design Observational cross-sectional study.Methods With the 1992 to 2000 data that was provided by the National Cancer Institute's Surveillance, Epidemiology, and End Results Program, we calculated age-adjusted incidence rates of uveal melanoma in various racial/ethnic groups (black, Asian and Pacific Islander, Hispanic, and non-Hispanic white). In addition, we calculated the standard incidence ratio (risk ratio) and 95% confidence interval to describe the differences within these racial/ethnic groups.Results From 1992 to 2000, there were a total of 1352 uveal melanomas that were diagnosed in 11 Surveillance, Epidemiology, and End Results registries with known racial/ethnic groups. The annual age-adjusted incidence (per million population) of uveal melanoma was 0.31 (black), 0.38 (Asian), 1.67 (Hispanic), and 6.02 (non-Hispanic white). The difference in the incidence of uveal melanoma between each racial/ethnic group was highly statistically significant, with the exception of the black versus the Asian population in which there was no statistically significant difference.Conclusion The relative risk of uveal melanoma was 1.2 for Asian and Pacific Islander patients, 5.4 for Hispanic patients, and 19.2 for non-Hispanic white patients as compared with the black patients. If the non-Hispanic white population and the Hispanic population were combined, then the overall white:black ratio was 18:1.
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“Incidentally, melanoma is not only associated with UV light exposure but also with European ancestry, occurring at very low rates in Africans, African Americans, and even light-skinned Asians (32)(33)(34).”
From Evidence for recent, population-specific evolution of the human mutation rate (2015) · cites this paper as [33]
In the citing paper
“Melanoma incidence in admixed Hispanics is strongly correlated with European ancestry (33)(34)(35).”
From Evidence for recent, population-specific evolution of the human mutation rate (2015) · cites this paper as [33]
Citations
Cites
Rodríguez‐Sains, R. S., Bart, R. S., Kopf, A. W., & Hölzle, E. (1979) · Cited by 1,287
Ophthalmic Pathology: An Atlas and Textbook
(1953) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1953.tb96223.x · Cited by 555
Epidemiologic aspects of uveal melanoma
Egan, K. M., Seddon, J. M., Glynn, R. J., Gragoudas, E. S., & Albert, D. M. (1988) · Survey of Ophthalmology · doi:10.1016/0039-6257(88)90173-7 · Cited by 528
Incidence of uveal melanoma in the United States: 1973–1997
Singh, A. D., & Topham, A. (2003) · Ophthalmology · doi:10.1016/s0161-6420(03)00078-2 · Cited by 517
Racial/ethnic patterns of cancer in the United States, 1988-1992.
Miller, B.-A., Kolonel, L. N., Bernstein, L., Young, J. L., Swanson, G., West, D. W., Key, C., Liff, J. M., Glover, C. S., & Alexander, G. A. (1996) · Cited by 500
Melanomas of the Eye and Other Noncutan eous Sites: Epidemiologic Aspects
Scotto, J., Fraumeni, J. F., & Lee, J. (1976) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/56.3.489 · Cited by 382
Cress, R. D., & Holly, E. A. (1997) · Cancer Causes & Control · doi:10.1023/a:1018432632528 · Cited by 296
Conjunctival melanoma: is it increasing in the United States?
Yu, G., Hu, D.-N., McCormick, S. A., & Finger, P. T. (2003) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(02)02288-2 · Cited by 227
Self-citationPROGNOSIS OF MALIGNANT MELANOMAS OF THE CHOROID AND CILIARY BODY
Paul, E. V., PARNELL, B. L., & Fraker, M. (1962) · International Ophthalmology Clinics · doi:10.1097/00004397-196206000-00007 · Cited by 220
Incidence of uveal melanoma in Sweden from 1960 to 1998.
Bergman, L., Seregard, S., Nilsson, B. R., Ringborg, U. K., Lundell, G. E. F., & Ragnarsson-Olding, B. K. (2002) · PubMed · Cited by 157
Uveal melanoma in relation to ultraviolet light exposure and host factors.
Holly, E. A., Aston, D. A., Char, D. H., Kristiansen, J. J., & Ahn, D. K. (1990) · PubMed · Cited by 152
Risk Factors for Ocular Melanoma: Western Canada Melanoma Study 2 3
Gallagher, R. P., Elwood, M., Rootman, J., Spinelli, J. J., Hill, G. B., Threlfall, W. J., & Birdsell, J. (1985) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/74.4.775 · Cited by 138
Racial differences in melanoma incidence
Crombie, I. K. (1979) · British Journal of Cancer · doi:10.1038/bjc.1979.165 · Cited by 124
Comparison of Methods for Classifying Hispanic Ethnicity in a Population-based Cancer Registry
STEWART, S. L., Swallen, K. C., Glaser, S. L., Horn‐Ross, P. L., & West, D. W. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009752 · Cited by 123
The Epidemiology of Ophthalmic Malignancies in New York State
Mahoney, M. C., Burnett, W. S., Majerovics, A., & Tanenbaum, H. L. (1990) · Ophthalmology · doi:10.1016/s0161-6420(90)32445-4 · Cited by 115
Ultraviolet light exposure as a risk factor for ocular melanoma in Queensland, Australia
Pane, A., & Hirst, L. W. (2000) · Ophthalmic Epidemiology · doi:10.1076/0928-6586(200009)731-vft159 · Cited by 85
Malignant Melanoma of the Choroid and Ciliary Body in Black Patients
Margo, C. E., & McLean, I. W. (1984) · Archives of Ophthalmology · doi:10.1001/archopht.1984.01040030061035 · Cited by 83
Trends in the incidence of ocular melanoma in the United States, 1974–1998
Inskip, P. D., Devesa, S. S., & Fraumeni, J. F. (2003) · Cancer Causes & Control · doi:10.1023/a:1023684502638 · Cited by 77
Incidence of surgically treated uveal melanoma by race and ethnicity
Margo, C. E. (1998) · Ophthalmology · doi:10.1016/s0161-6420(98)96012-2 · Cited by 77
Trends in incidence of ocular malignant melanoma in Denmark 1943–1982
Østerlind, A. (1987) · International Journal of Cancer · doi:10.1002/ijc.2910400206 · Cited by 76
KUO, P. K., Puliafito, C. A., WANG, K. M., LIU, H. S., & WU, B. F. (1982) · International Ophthalmology Clinics · doi:10.1097/00004397-198202230-00007 · Cited by 63
Albert, D. M., Puliafito, C. A., Fulton, A. B., Robinson, N., Zakov, Z. N., Dryja, T. P., Smith, A. B., Egan, E., & Leffingwell, S. S. (1980) · American Journal of Ophthalmology · doi:10.1016/0002-9394(80)90001-x · Cited by 52
Uveal melanomas in black patients: a case series and comparative review.
Phillpotts, B. A., Sanders, R. J., Shields, J. A., Griffiths, J. D., Augsburger, J., & Shields, C. L. (1995) · PubMed Central · Cited by 46
Ocular malignant melanoma in South African blacks.
Miller, B., Abrahams, C., COLE, G., & Proctor, N. S. F. (1981) · British Journal of Ophthalmology · doi:10.1136/bjo.65.10.720 · Cited by 45
Ocular Melanoma Task Force Report
Graham, B. J., & Duane, T. D. (1980) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(14)75147-5 · Cited by 41
Use of Spanish surnames to identify Latinos: comparison to self-identification.
Pérez‐Stable, E. J., Hiatt, R., Sabogal, F., & Otero‐Sabogal, R. (1995) · PubMed · Cited by 36
Epidemiology of melanoma of the eye in the Oxford Region, 1952-78
Swerdlow, A. J. (1983) · British Journal of Cancer · doi:10.1038/bjc.1983.42 · Cited by 33
Conjunctival Melanoma in the Black Population
Singh, A. D., Campos, O. E., Rhatigan, R. M., Schulman, J. A., & Misra, R. (1998) · Survey of Ophthalmology · doi:10.1016/s0039-6257(98)00020-4 · Cited by 30
Incidence of choroidal malignant melanoma in Finland in the years 1973–1980
Teikari, J. M., & Raivio, I. (1985) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.1985.tb01577.x · Cited by 30
OCULAR PATHOLOGY, A TEXT AND ATLAS, 3rd ed
Williams, T. D. (1989) · Optometry and Vision Science · doi:10.1002/j.1538-9235.1989.tb02427.x · Cited by 29
Malignant melanoma of the uvea in Iceland 1955–1979
Gíslason, I., Magnússon, B., & Tulinius, H. (1985) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.1985.tb01550.x · Cited by 24
Epidemiologic aspects of intraocular malignant melanoma
Gallagher, R. P., Elwood, M., & Rootman, J. (1988) · Cancer treatment and research · doi:10.1007/978-1-4613-1751-7_5 · Cited by 10
Research works printed but not linked: 4
- Phillpotts, 1995, Uveal melanomas in black patients, J Natl Med Assoc, 87, 709
- Gallagher, 1985, Risk factors for ocular melanoma, J Natl Cancer Inst, 74, 775
- Perez-Stable, 1995, Use of Spanish surnames to identify Latinos, J Natl Cancer Inst Monogr, 18, 11
- Cress, 1997, Incidence of cutaneous melanoma among non-Hispanic whites, Hispanics, Asians, and blacks, Cancer Causes Control, 8, 246
Cited by
Sorted by citations
Uveal melanoma: relatively rare but deadly cancer
Kaliki, S., & Shields, C. L. (2016) · Eye · doi:10.1038/eye.2016.275 · Cited by 675
The Molecular Pathology of Melanoma: An Integrated Taxonomy of Melanocytic Neoplasia
Bastian, B. C. (2014) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-012513-104658 · Cited by 540
Incidence of Uveal Melanoma in Europe
Virgili, G., Gatta, G., Ciccolallo, L., Capocaccia, R., Biggeri, A., Crocetti, E., Lutz, J.-M., & Paci, E. (2007) · Ophthalmology · doi:10.1016/j.ophtha.2007.01.032 · Cited by 484
Uveal melanoma: epidemiology, etiology, and treatment of primary disease
Krantz, B. A., Dave, N., Komatsubara, K. M., Marr, B. P., & Carvajal, R. D. (2017) · Clinical ophthalmology · doi:10.2147/opth.s89591 · Cited by 422
Simon, J. D., Peles, D., Wakamatsu, K., & Ito, S. (2009) · Pigment Cell & Melanoma Research · doi:10.1111/j.1755-148x.2009.00610.x · Cited by 391
“Specifically, epidemiological studies on the relationship between iridal color and incidence of uveal melanoma suggest that the light-colored eye (blue, hazel, etc.) and Caucasian is at a higher risk than the dark-colored eye and African-Asians (Hu et al., 2005; Vajdic et al., 2001).”
Background
Metadata
- Authors
- Hu, D.-N., Yu, G.-P., McCormick, S. A., Schneider, S., & Finger, P. T.
- Affiliations
- New York Eye and Ear Infirmary (US)
- New York Medical College (US)
- Corresponding author
- Hu, Dan-Ning
- Venue
- American Journal of Ophthalmology
- Publisher
- Elsevier BV
- Published
- 2005-10
- Volume
- 140
- Issue
- 4
- Pages
- 612.e1-612.e8
- ISSN
- 0002-9394 (ISSN-L)
- OpenAlex
- W2061857205
- Cited by
- 238
- References
- 36
- Citations by year
- 2026: 9 · 2025: 19 · 2024: 17 · 2023: 17 · 2022: 16 · 2021: 15 · 2020: 13 · 2019: 13 · 2018: 8 · 2017: 14 · 2016: 9 · 2015: 10 · 2014: 10 · 2013: 17 · 2012: 11
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Ophthalmology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Ophthalmology › Ocular Oncology and Treatments
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Keywords
- uveal melanoma, racial and ethnic differences, cancer incidence, age-adjusted incidence, Hispanic population, Asian and Pacific Islander populations, Black population, non-Hispanic whites, SEER database, relative risk
- MeSH terms
- Cross-Sectional Studies, Ethnicity, Female, Humans, Male, Melanoma, Risk Factors, United States, Uveal Neoplasms, Incidence, SEER Program, Racial Groups
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