Cited by 267Pelvic floor disorders treatmentsPregnancy-related medical researchSexual function and dysfunction studies

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Graphic integration of causal factors of pelvic floor disorders: an integrated life span model

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DeLancey, John O.L., Kane Low, Lisa, Miller, Janis M., Patel, Divya A., Tumbarello, Julie A.·2008·American Journal of Obstetrics and Gynecology

Abstract

There is growing interest in causal factors for pelvic floor disorders. These conditions include pelvic organ prolapse and urinary and fecal incontinence and are affected by a myriad of factors that increase occurrence of symptomatic disease. Unraveling the complex causal network of genetic factors, birth-induced injury, connective tissue aging, lifestyle and comorbid factors is challenging. We describe a graphical tool to integrate the factors affecting pelvic floor disorders. It plots pelvic floor function in 3 major life phases: (1) development of functional reserve during an individual's growth, (2) variations in the amount of injury and potential recovery that occur during and after vaginal birth, and (3) deterioration that occurs with advancing age. This graphical tool accounts for changes in different phases to be integrated to form a disease model to help assess the overlap of different causal factors.

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Crossref · 10.1016/j.ajog.2008.04.001

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Metadata

Authors
DeLancey, J. O. L., Kane Low, L., Miller, J. M., Patel, D. A., & Tumbarello, J. A.
Affiliations
University of Michigan (US)
Corresponding author
DeLancey, John O.L.
Venue
American Journal of Obstetrics and Gynecology
Publisher
Elsevier BV
Published
2008-12
Volume
199
Issue
6
Pages
610.e1-610.e5
ISSN
0002-9378 (ISSN-L)
OpenAlex
W2142301107
Cited by
267
References
7
Citations by year
2026: 11 · 2025: 18 · 2024: 32 · 2023: 21 · 2022: 33 · 2021: 12 · 2020: 27 · 2019: 14 · 2018: 12 · 2017: 12 · 2016: 12 · 2015: 13 · 2014: 11 · 2013: 10 · 2012: 5
FWCI
4.86
Type
journal article
Language
en
Open access
Locations
  • American Journal of Obstetrics and Gynecology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (P50HD044406)
Topics
  • Health Sciences › Medicine › Urology › Pelvic floor disorders treatments
  • Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy-related medical research
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Keywords
pelvic floor dysfunction, causal factors, pelvic organ prolapse, urinary incontinence, fecal incontinence, probabilistic graphical models, connective tissue aging, genetic factors, disease models
MeSH terms
Adolescent, Adult, Aged, Chronic Disease, Computer Graphics, Computer Simulation, Fecal Incontinence, Female, Humans, Human Development, Life Style, Middle Aged, Models, Biological, Pregnancy, Quality of Life, Risk Factors, Sensitivity and Specificity, Severity of Illness Index, Urinary Incontinence, Uterine Prolapse, Comorbidity, Incidence, Age Distribution, Pelvic Floor, Delivery, Obstetric, Young Adult

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