Prevalence, trends, and outcomes of chronic hypertension: a nationwide sample of delivery admissions
Open accessAbstract
Objective We sought to define the prevalence, trends, and outcomes of primary and secondary chronic hypertension in a population-based sample of deliveries.Study design An estimated 56,494,634 deliveries were identified from the 1995 through 2008 Nationwide Inpatient Sample. The association of primary and secondary chronic hypertension with adverse fetal and maternal outcomes was evaluated using regression modeling and adjusted population-attributable fractions were calculated.Results During the study period, the prevalence of primary and secondary hypertension increased from 0.90% in 1995 through 1996 to 1.52% in 2007 through 2008 (P for trend < .001) and from 0.07% to 0.24% (P for trend < .001), respectively. The population-attributable fraction for chronic hypertension was considerable for many maternal adverse outcomes, including acute renal failure (21%), pulmonary edema (14%), preeclampsia (11%), and in-hospital mortality (10%).Conclusion Primary and secondary chronic hypertension were both strongly associated with adverse pregnancy outcomes and accounted for a substantial fraction of maternal morbidity. Prioritizing research efforts in this area is needed.
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Cardiomyopathy, thromboembolic disease, and postpartum hemorrhage are especially prevalent in older women.
“For instance, cardiomyopathy, thromboembolic disease, and postpartum hemorrhage are especially prevalent in older women [36, 37].”
From Age-related disparities in national maternal mortality trends: A population-based study (2025) · cites this paper as [37]
The Introduction links advanced maternal age to a likely rise in chronic hypertension, while the Comment discusses other adverse maternal outcomes associated with hypertension. Searches for cardiomyopathy, thromboembolic disease, and postpartum hemorrhage found no passage saying these conditions are especially prevalent in older women. No page numbers were available in our copy. (LLM, conf=0.77)
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- Authors
- Bateman, B. T., Bansil, P., Hernandez-Diaz, S., Mhyre, J. M., Callaghan, W. M., & Kuklina, E. V.
- Affiliations
- Harvard University (US)
- Centers for Disease Control and Prevention (US)
- Michigan Medicine (US)
- Corresponding author
- Bateman, Brian T.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2012-02
- Volume
- 206
- Issue
- 2
- Pages
- 134.e1-134.e8
- ISSN
- 0002-9378 (ISSN-L)
- PMC
- PMC4103984
- OpenAlex
- W2016362094
- Cited by
- 323
- References
- 26
- Citations by year
- 2026: 11 · 2025: 18 · 2024: 37 · 2023: 32 · 2022: 33 · 2021: 34 · 2020: 29 · 2019: 32 · 2018: 26 · 2017: 19 · 2016: 9 · 2015: 19 · 2014: 8 · 2013: 7 · 2012: 7
- FWCI
- 9.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of General Medical Sciences (T32GM007592)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Neurological Complications and Syndromes
- Keywords
- chronic hypertension, essential hypertension, secondary hypertension, pregnancy, prevalence trends, maternal morbidity, adverse pregnancy outcomes, preeclampsia, acute kidney injury, pulmonary edema, in-hospital mortality, population attributable fraction
- MeSH terms
- Adolescent, Adult, Female, Hospitalization, Humans, Pregnancy, United States, Prevalence, Hypertension, Pregnancy-Induced
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