The DOI matches its Crossref record; 100 of the 100 references it cites were found in a registry or an index.
Placenta Accreta Spectrum
Open accessAbstract
Placenta accreta spectrum, formerly known as morbidly adherent placenta, refers to the range of pathologic adherence of the placenta, including placenta increta, placenta percreta, and placenta accreta. The most favored hypothesis regarding the etiology of placenta accreta spectrum is that a defect of the endometrial-myometrial interface leads to a failure of normal decidualization in the area of a uterine scar, which allows abnormally deep placental anchoring villi and trophoblast infiltration. Maternal morbidity and mortality can occur because of severe and sometimes life-threatening hemorrhage, which often requires blood transfusion. Although ultrasound evaluation is important, the absence of ultrasound findings does not preclude a diagnosis of placenta accreta spectrum; thus, clinical risk factors remain equally important as predictors of placenta accreta spectrum by ultrasound findings. There are several risk factors for placenta accreta spectrum. The most common is a previous cesarean delivery, with the incidence of placenta accreta spectrum increasing with the number of prior cesarean deliveries. Antenatal diagnosis of placenta accreta spectrum is highly desirable because outcomes are optimized when delivery occurs at a level III or IV maternal care facility before the onset of labor or bleeding and with avoidance of placental disruption. The most generally accepted approach to placenta accreta spectrum is cesarean hysterectomy with the placenta left in situ after delivery of the fetus (attempts at placental removal are associated with significant risk of hemorrhage). Optimal management involves a standardized approach with a comprehensive multidisciplinary care team accustomed to management of placenta accreta spectrum. In addition, established infrastructure and strong nursing leadership accustomed to managing high-level postpartum hemorrhage should be in place, and access to a blood bank capable of employing massive transfusion protocols should help guide decisions about delivery location.
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“ML, with its ability to read complex imaging data [17] and to reduce the dependence on operator skill, has great potential as a method of improving consistency and enabling earlier diagnosis of PAS [6].”
From Machine Learning in Maternity: Early Diagnosis of Placenta Accreta Spectrum (2026) · cites this paper as [6]
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Maternal Morbidity Associated With Multiple Repeat Cesarean Deliveries
Silver, R. M., Landon, M. B., Rouse, D. J., Leveno, K. J., Spong, C. Y., Thom, E. A., Moawad, A. H., Caritis, S. N., Harper, M., Wapner, R. J., et al. (2006) · Obstetrics & Gynecology · doi:10.1097/01.aog.0000219750.79480.84 · Cited by 1,909
Self-citationShakur‐Still, H., Roberts, I., Fawole, B., Chaudhri, R., El-Sheikh, M., Akintan, A., Qureshi, Z. P., Kidanto, H. L., Vwalika, B., Abdosh, A. A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30638-4 · Cited by 1,472
Practice Bulletin No. 183: postpartum hemorrhage
(2017) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000002351 · Cited by 1,406
Abnormal placentation: Twenty-year analysis
Wu, S., Kocherginsky, M., & Hibbard, J. U. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.12.074 · Cited by 1,331
Clinical risk factors for placenta previa–placenta accreta
Miller, D. A. W., Chollet, J. A., & Goodwin, T. M. (1997) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(97)70463-0 · Cited by 1,112
Jauniaux, E., Collins, S., & Burton, G. J. (2018) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.05.067 · Cited by 775
The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage
CHARBIT, B., MANDELBROT, L., SAMAIN, E., BARON, G., HADDAOUI, B., KEITA, H., SIBONY, O., MAHIEU‐CAPUTO, D., HURTAUD‐ROUX, M. F., HUISSE, M. G., et al. (2007) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2007.02297.x · Cited by 762
Practice Guidelines for Obstetric Anesthesia
(2015) · Anesthesiology · doi:10.1097/aln.0000000000000935 · Cited by 705
Optimal management strategies for placenta accreta
Eller, A., Porter, T., Soisson, P., & Silver, R. (2009) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2008.02037.x · Cited by 578
Self-citationImpact of multiple cesarean deliveries on maternal morbidity: a systematic review
Marshall, N. E., Fu, R., & Guise, J.-M. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2011.06.035 · Cited by 565
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Cesarean section one hundred years 1920–2020: the Good, the Bad and the Ugly
Antoine, C., & Young, B. K. (2020) · Journal of Perinatal Medicine · doi:10.1515/jpm-2020-0305 · Cited by 296
Hecht, J. L., Baergen, R., Ernst, L. M., Katzman, P. J., Jacques, S. M., Jauniaux, E., Khong, T. Y., Metlay, L. A., Poder, L., Qureshi, F., et al. (2020) · Modern Pathology · doi:10.1038/s41379-020-0569-1 · Cited by 263
Matsuzaki, S., Mandelbaum, R. S., Sangara, R. N., McCarthy, L. E., Vestal, N. L., Klar, M., Matsushima, K., Amaya, R., Ouzounian, J. G., & Matsuo, K. (2021) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2021.04.233 · Cited by 221
Suárez, S., Conde‐Agudelo, A., Borovac‐Pinheiro, A., Suarez-Rebling, D., Eckardt, M. J., Theron, G. B., & Burke, T. F. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2019.11.1287 · Cited by 221
Kingdom, J. C., Hobson, S. R., Murji, A., Allen, L. M., Windrim, R. C., Lockhart, E. L., Collins, S., majd, H. S., Alazzam, M., Naaisa, F., et al. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.01.044 · Cited by 133
Metadata
- Authors
- Cahill, A. G., Beigi, R., Heine, R. P., Silver, R. M., & Wax, J. R.
- Affiliations
- Society for Maternal-Fetal Medicine (US)
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2018-12
- Volume
- 219
- Issue
- 6
- Pages
- B2-B16
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2901857044
- Cited by
- 481
- References
- 99
- Citations by year
- 2026: 34 · 2025: 76 · 2024: 82 · 2023: 85 · 2022: 62 · 2021: 70 · 2020: 42 · 2019: 25
- FWCI
- 38.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
- Health Sciences › Medicine › Hematology › Blood transfusion and management
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Keywords
- placenta accreta spectrum, placenta increta, placenta percreta, placenta accreta, decidualization, uterine scar, cesarean section, postpartum hemorrhage, prenatal diagnosis, cesarean hysterectomy, placental retention, risk factors, multidisciplinary care, massive transfusion
- MeSH terms
- Cesarean Section, Female, Gynecology, Humans, Hysterectomy, Obstetrics, Placenta Accreta, Pregnancy, Prenatal Diagnosis, Societies, Medical, United States
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