Effect of sacrospinous hysteropexy with graft vs vaginal hysterectomy with uterosacral ligament suspension on treatment failure in women with uterovaginal prolapse: 5-year results of a randomized clinical trial
Open accessAbstract
Background Vaginal hysterectomy with suture apical suspension is commonly performed for uterovaginal prolapse. Sacrospinous hysteropexy with graft (vaginal mesh hysteropexy) is an alternative, although in 2019 the Food and Drug Administration removed this mesh product from the United States market.Objective Our objective was to compare the efficacy and adverse events of these 2 procedures.Study design At 9 clinical sites in the United States National Institutes of Health and National Institute of Child Health and Human Development Pelvic Floor Disorders Network, 183 postmenopausal women requesting vaginal surgery for symptomatic uterovaginal prolapse were enrolled in a multisite randomized superiority clinical trial, comparing a sacrospinous hysteropexy with graft (hysteropexy) with a vaginal hysterectomy with uterosacral ligament suspension (hysterectomy). Participants consented to remain masked to treatment assignment for the study duration. Study visits were conducted at 6-month intervals through 60 months. The primary treatment failure composite outcome (retreatment of prolapse, prolapse beyond the hymen, or prolapse symptoms) was evaluated with survival modeling. Secondary outcomes included complications or adverse events, individual anatomic measures of the pelvic organ prolapse quantification examination, and presence, severity, and impact and bother of prolapse, urinary, bowel, and pain symptoms as measured by validated questionnaires. The 3-year published results suggested better primary outcomes with sacrospinous hysteropexy with graft, but the differences were not statistically significant (P=.06). This study reports the 5-year outcomes.Results A total of 183 women with a mean age of 66 years were randomized between April 2013 and February 2015; 93 were randomized to hysteropexy and 90 were randomized to hysterectomy. Notably, 175 were included in the trial, and 156 (89%) completed the 5-year follow-up. The primary outcome showed fewer failures for hysteropexy than hysterectomy through 5 years (adjusted hazard ratio, 0.58; 95% confidence interval, 0.36-0.94; P=.03), with failure rates of 37% vs 54%, respectively, resulting in a difference of -18% (95% confidence interval, -33% to -3%) at 5 years. With the exception of the Urogenital Distress Inventory, no group differences were demonstrated in patient-reported pelvic floor symptoms, prolapse symptoms, bowel function symptoms, general quality of life, body image, or pelvic pain. At their last visit through 5 years, 70% of participants (129 of 183) reported they remained masked to their treatment with no difference in masking between groups. Adverse events for hysteropexy vs hysterectomy included mesh exposure (8% vs 0%), granulation tissue after 12 weeks (1% vs 12%), and suture exposure after 12 weeks (3% vs 21%), respectively.Conclusion Among women with symptomatic uterovaginal prolapse undergoing vaginal surgery, sacrospinous hysteropexy with graft resulted in a lower composite failure rate than vaginal hysterectomy through 5 years. There were no meaningful differences in patient-reported outcomes between groups. Our results suggest that this vaginal mesh hysteropexy procedure should be made available to patients.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the SUPeR trial, among women with symptomatic uterovaginal prolapse undergoing vaginal surgery, sacrospinous hysteropexy with graft resulted in a lower composite surgical failure rate than vaginal hysterectomy with uterosacral ligament suspension over 5 years (aHR 0.58; 95% CI 0.36-0.94; P=.03).
“Among women with symptomatic uterovaginal prolapse undergoing vaginal surgery in the vaginal hysterectomy with uterosacral ligament suspension (USLS) vs sacrospinous hysteropexy with graft suspension (Study for Uterine Prolapse Procedures Randomized Trial [SUPeR]) trial, sacrospinous hysteropexy with graft resulted in a lower composite surgical failure rate than vaginal hysterectomy with USLS over”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
WARE, J. E., KOSINSKI, M., & KELLER, S. D. (1996) · Medical Care · doi:10.1097/00005650-199603000-00003 · Cited by 17,392 · see citing works
The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction
Bump, R. C., Mattiasson, A., Bø, K., Brubaker, L. P., DeLancey, J. O. L., Klarskov, P., Shull, B. L., & Smith, A. R. B. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70243-0 · Cited by 4,275 · see citing works
Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery
Wu, J. M., Matthews, C. A., Conover, M. M., Pate, V., & Jonsson Funk, M. (2014) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000000286 · Cited by 1,111 · see citing works
A body image scale for use with cancer patients
Hopwood, P., Fletcher, I., Lee, A., & Al Ghazal, S. (2001) · European Journal of Cancer · doi:10.1016/s0959-8049(00)00353-1 · Cited by 984 · see citing works
Validation of two global impression questionnaires for incontinence
Yalcin, I., & Bump, R. C. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2003.379 · Cited by 888 · see citing works
Barber, M. D., Kuchibhatla, M. N., Pieper, C. F., & Bump, R. C. (2001) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2001.118659 · Cited by 617 · see citing works
Jelovsek, J. E., & Barber, M. D. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2006.01.060 · Cited by 434 · see citing works
Surgery for women with apical vaginal prolapse
Maher, C., Feiner, B., Baeßler, K., Christmann‐Schmid, C., Haya, N., & Brown, J. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012376 · Cited by 424 · see citing works
Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse
Maher, C., Feiner, B., Baeßler, K., Christmann‐Schmid, C., Haya, N., & Marjoribanks, J. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012079 · Cited by 345 · see citing works
Test‐Based Exact Confidence Intervals for the Difference of Two Binomial Proportions
Chan, I. S. F., & Zhang, Z. (1999) · Biometrics · doi:10.1111/j.0006-341x.1999.01202.x · Cited by 292 · see citing works
Jelovsek, J. E., Barber, M. D., Brubaker, L., Norton, P., Gantz, M., Richter, H. E., Weidner, A., Menefee, S., Schaffer, J., Pugh, N., et al. (2018) · JAMA · doi:10.1001/jama.2018.2827 · Cited by 256 · see citing works
Self-citationMeriwether, K. V., Antosh, D. D., Olivera, C. K., Kim-Fine, S., Balk, E. M., Murphy, M., Grimes, C. L., Sleemi, A., Singh, R., Dieter, A. A., et al. (2018) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2018.01.018 · Cited by 254 · see citing works
Randomization in Clinical Trials: Permuted Blocks and Stratification
Broglio, K. (2018) · JAMA · doi:10.1001/jama.2018.6360 · Cited by 243 · see citing works
Wellner, J. A., & Zhan, Y. (1997) · Journal of the American Statistical Association · doi:10.1080/01621459.1997.10474049 · Cited by 211 · see citing works
Rogers, R. G., Rockwood, T. H., Constantine, M. L., Thakar, R., KAMMERER-DOAK, D. N., Pauls, R. N., Parekh, M. H., Ridgeway, B., Jha, S., Pitkin, J., et al. (2013) · International Urogynecology Journal · doi:10.1007/s00192-012-2020-8 · Cited by 204 · see citing works
Detollenaere, R. J., den Boon, J., Stekelenburg, J., IntHout, J., Vierhout, M. E., Kluivers, K. B., & van Eijndhoven, H. W. F. (2015) · BMJ · doi:10.1136/bmj.h3717 · Cited by 194 · see citing works
Assessment of Patient Functional Status after Surgery
MCCARTHY, M. J., JONASSON, O. M., Chang, C., Pickard, A. S., Giobbie‐Hurder, A., Gibbs, J. O., Edelman, P., Fitzgibbons, R., & Neumayer, L. A. (2005) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2005.03.035 · Cited by 153 · see citing works
Nager, C. W., Visco, A. G., Richter, H. E., Rardin, C. R., Rogers, R. G., Harvie, H. S., Zyczynski, H. M., Paraiso, M. F. R., Mazloomdoost, D., Grey, S., et al. (2019) · JAMA · doi:10.1001/jama.2019.12812 · Cited by 103 · see citing works
Self-citationThe PISQ-IR: considerations in scale scoring and development
Rockwood, T. H., Constantine, M. L., Adegoke, O. O., Rogers, R. G., McDermott, E., Davila, G. W., Domoney, C., Jha, S., KAMMERER-DOAK, D. N., Lukacz, E. S., et al. (2013) · International Urogynecology Journal · doi:10.1007/s00192-012-2037-z · Cited by 55 · see citing works
Madsen, A. M., Raker, C., & Sung, V. W. (2017) · Urogynecology · doi:10.1097/spv.0000000000000426 · Cited by 45 · see citing works
On the variance estimator for the Mantel-Haenszel risk difference
Sato, T. S. (1989) · Biometrics · Cited by 35 · see citing works
Nager, C. W., Zyczynski, H., Rogers, R. G., Barber, M. D., Richter, H. E., Visco, A. G., Rardin, C. R., Harvie, H., Wallace, D., & Meikle, S. F. (2016) · Female Pelvic Medicine & Reconstructive Surgery · doi:10.1097/spv.0000000000000270 · Cited by 27 · see citing works
Self-citationSandvik, H., Seim, A., Vanvik, A., & Hunskaar, S. (2000) · Neurourology and Urodynamics · doi:10.1002/(sici)1520-6777(2000)19:2
Flagged first, then by citations
Research works printed but not linked: 1
- [25]Hopwood P, Fletcher I, Lee A, Al Ghazal S. A body image scale for use with cancer patients. European Journal of Cancer 2001; 37: 189– 97. 11166145
Cited by
Sorted by citations
Surgery for women with apical vaginal prolapse
Maher, C., Yeung, E., Haya, N., Christmann-Schmid, C., Mowat, A., Chen, Z., & Baessler, K. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012376.pub2 · Cited by 114 · see citing works
Long-term reoperation risk after apical prolapse repair in female pelvic reconstructive surgery
Shah, N. M., Berger, A. A., Zhuang, Z., Tan-Kim, J., & Menefee, S. A. (2022) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2022.05.046 · Cited by 45 · see citing works
Apical Suspension Repair for Vaginal Vault Prolapse
Menefee, S. A., Richter, H. E., Myers, D. L., Moalli, P., Weidner, A. C., Harvie, H. S., Rahn, D. D., Meriwether, K. V., Paraiso, M. F. R., Whitworth, R., et al. (2024) · JAMA Surgery · doi:10.1001/jamasurg.2024.1206 · Cited by 41 · see citing works
Self-citationTransvaginal Mesh Compared With Native Tissue Repair for Pelvic Organ Prolapse
Kahn, B. S., Varner, R. E., Murphy, M., Sand, P. K., Thomas, S. L., Lipetskaia, L., Chung, D. E., Mahdy, A. E., & Noblett, K. L. (2022) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000004794 · Cited by 29 · see citing works
Self-citationTransvaginal mesh or grafts or native tissue repair for vaginal prolapse
Yeung, E., Baeßler, K., Christmann‐Schmid, C., Haya, N., Chen, Z., Wallace, S. A., Mowat, A., & Maher, C. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012079.pub2 · Cited by 30 · see citing works
A systematic review of the surgical management of apical pelvic organ prolapse
Chan, C. Y. W., Fernandes, R. A., Yao, H. H., O’Connell, H. E., Tse, V. W., & Gani, J. (2022) · International Urogynecology Journal · doi:10.1007/s00192-022-05408-x · Cited by 28 · see citing works
Permanent Compared With Absorbable Suture in Apical Prolapse Surgery
Pollack, B. L., Popiel, P., Toaff, M. C., Drugge, E. D., Bielawski, A., Sacks, A., Bibi, M., Friedman-Ciment, R., LeBron, K., Alishahian, L., et al. (2023) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000005032 · Cited by 22 · see citing works
Darzi, S., Alappadan, J., Paul, K., Mazdumder, P., Rosamilia, A., Truong, Y. B., Gargett, C. E., Werkmeister, J. A., & Mukherjee, S. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213669 · Cited by 21 · see citing works
Measuring Pelvic Organ Prolapse: An Evolution
Barber, M. D. (2024) · International Urogynecology Journal · doi:10.1007/s00192-024-05798-0 · Cited by 23 · see citing works
Culligan, P. J., Saiz, C. M., & Rosenblatt, P. L. (2022) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000004761 · Cited by 16 · see citing works
European Urogynaecological Association Position Statement: Pelvic Organ Prolapse Surgery
Padoa, A., Braga, A., Fligelman, T., Athanasiou, S., Phillips, C., Salvatore, S., & Serati, M. (2023) · Urogynecology · doi:10.1097/spv.0000000000001396 · Cited by 14 · see citing works
Longitudinal Reoperation Risk After Apical Prolapse Procedures in Women Aged 65 Years and Older
Berger, A. A., Bretschneider, C. E., Gregory, W. T., & Sung, V. W. (2024) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000005511 · Cited by 14 · see citing works
Gracia, S. D., Fatton, B., Cosson, M., Campagne-Loiseau, S., Ferry, P., Lucot, J.-P., Debodinance, P., Panel, L., Deffieux, X., Garbin, O., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12020468 · Cited by 13 · see citing works
Birol, P., Yassa, M., Doğan, O., Tekin, A. B., Günkaya, O. S., Yassa, M., Saçıntı, K. G., Alsannan, B., Dağdeviren, H., Tuğ, N., et al. (2024) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2024.09.007 · Cited by 13 · see citing works
Giugale, L. E., Sridhar, A., Ferrante, K. L., Komesu, Y. M., Meyer, I., Smith, A. L., Myers, D., Visco, A. G., Paraiso, M. F. R., Mazloomdoost, D., et al. (2022) · Urogynecology · doi:10.1097/spv.0000000000001160 · Cited by 11 · see citing works
Self-citationQin, Z., Dong, Z., Tang, H., Zhang, S., Wang, H., Bao, M., Wei, W., Shi, R., Chen, J., & Xia, B. (2022) · Frontiers in Surgery · doi:10.3389/fsurg.2022.931691 · Cited by 12 · see citing works
Efficacy and safety of transvaginal mesh repair in a cohort with a minimum of 10-year follow-up
Zhang, Z., Guo, J., Tian, W., Zhang, Y., Zhang, Y., Sun, T., Duan, J., Bao, X., Wang, Y., Ye, Y., et al. (2024) · Science China Life Sciences · doi:10.1007/s11427-023-2508-x · Cited by 9 · see citing works
Paul, K., Darzi, S., O’Connell, C. D., Hennes, D. M. Z. B., Rosamilia, A., Gargett, C. E., Werkmeister, J. A., & Mukherjee, S. (2024) · Advanced Science · doi:10.1002/advs.202405004 · Cited by 9 · see citing works
Body image and sexual function improve following prolapse repair
Andy, U. U., Nowak, K. J., Menefee, S. A., Shinnick, J. K., Mueller, M. G., Woll, A., Rodriguez, M. E. F., Mazloomdoost, D., & Whitworth, R. (2025) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.01.042 · Cited by 8 · see citing works
Self-citationBradley, M. S., Sridhar, A., Ferrante, K. L., Andy, U. U., Visco, A. G., Rodriguez, M. E. F., Myers, D. L., Varner, E. R., Mazloomdoost, D., Gantz, M. G., et al. (2022) · Urogynecology · doi:10.1097/spv.0000000000001309 · Cited by 8 · see citing works
Self-citationRole of Hysteropexy in the Management of Pelvic Organ Prolapse
Gan, Z. S., Roberson, D. S., & Smith, A. L. (2022) · Current Urology Reports · doi:10.1007/s11934-022-01101-0 · Cited by 7 · see citing works
Noor, N., Bastawros, D. A., Florian-Rodriguez, M. E., Hobson, D., Eto, C. U., Lozo, S., Lavelle, E. S., Antosh, D. D., Hacker, M. R., Elkadry, E. A., et al. (2022) · Urogynecology · doi:10.1097/spv.0000000000001226 · Cited by 7 · see citing works
Review of Vaginal Approaches to Apical Prolapse Repair
Lua, L. L., Wallace, S. L., Khan, F. A., Kannikal, J. J., Israeli, J. M., & Syan, R. (2022) · Current Urology Reports · doi:10.1007/s11934-022-01124-7 · Cited by 8 · see citing works
Ex Vivo Uniaxial Tensile Properties of Rat Uterosacral Ligaments
Donaldson, K., & Vita, R. D. (2023) · Annals of Biomedical Engineering · doi:10.1007/s10439-023-03135-y · Cited by 7 · see citing works
Chang, O. H., Yao, M., Ferrando, C. A., Paraiso, M. F. R., & Propst, K. A. (2023) · Sexual Medicine · doi:10.1093/sexmed/qfad006 · Cited by 7 · see citing works
Self-citationRichter, H. E., Sridhar, A., Nager, C. W., Komesu, Y. M., Harvie, H. S., Zyczynski, H. M., Rardin, C., Visco, A., Mazloomdoost, D., & Thomas, S. (2023) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2022.07.048 · Cited by 7 · see citing works
Self-citationPelvic Organ Prolapse: Overview, Diagnosis and Management
El‐Nashar, S. A., Singh, R., & Chen, A. H. (2022) · Journal of Gynecologic Surgery · doi:10.1089/gyn.2022.0049 · Cited by 8 · see citing works
Sacrospinous ligament fixation (SSLF): an old method with new horizons
Leron, E., Erez, O., Shwarzmam, P., & Baeßler, K. (2022) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-022-06508-1 · Cited by 6 · see citing works
Rehabilitation Therapies in Pelvic Floor Dysfunction for Women
Chen, J., & Luo, J. (2025) · Journal of Community Health Nursing · doi:10.1080/07370016.2025.2549814 · Cited by 5 · see citing works
Surgery for women with pelvic organ prolapse with or without stress urinary incontinence
Baeßler, K., Christmann‐Schmid, C., Haya, N., Mowat, A. P., Chen, Z., Wallace, S. A., Yeung, E., & Maher, C. (2026) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013108.pub2 · Cited by 5 · see citing works
Restriction of Surgical Options for Pelvic Floor Disorders.
(2024) · Urogynecology · doi:10.1097/spv.0000000000001507 · Cited by 4 · see citing works
Birol, P., Keleş, E., Kırlangıç, M. M., Yıldız, G., Tekin, A. B., Budak, D., Gök, S., Dereli, M. L., Tuğ, N., Yassa, M., et al. (2025) · Minimally Invasive Therapy & Allied Technologies · doi:10.1080/13645706.2025.2500095 · Cited by 5 · see citing works
Carberry, C. L., Tulikangas, P. K., Ridgeway, B., Collins, S., & Adam, R. A. (2025) · Urogynecology · doi:10.1097/spv.0000000000001641 · Cited by 5 · see citing works
Lozo, S., Chill, H. H., Botros, C., Goldberg, R. P., & Gafni‐Kane, A. (2022) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2022.11.025 · Cited by 6 · see citing works
García‐Mejido, J. A., Martínez, A. M., González‐Díaz, E., Núñez‐Matas, M. J., Fernández‐Palacín, A., Carballo‐Rastrilla, S., Fernández‐Fernández, C., García-Jiménez, R., & Sainz‐Bueno, J. A. (2023) · Journal of Ultrasound in Medicine · doi:10.1002/jum.16303 · Cited by 5 · see citing works
The Role of Uterine Preservation at the Time of Pelvic Organ Prolapse Surgery
Chang, O. H., Carter Ramirez, A., Edwards, A., Chill, H. H., Letko, J., Woodburn, K. L., & Cundiff, G. W. (2025) · Urogynecology · doi:10.1097/spv.0000000000001667 · Cited by 4 · see citing works
Lo, T., Rellora, L. E., Rom, E., Chiung, H., Yang, C., & Lin, Y.-H. (2025) · International Urogynecology Journal · doi:10.1007/s00192-025-06105-1 · Cited by 4 · see citing works
Quality of Life Assessment After Pelvic Prolapse Surgery With and Without Mesh: A Literature Review
Pirtea, M., Balint, O., Secoşan, C. A., Costăchescu, D., Dabîca, A., & Navolan, D. B. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14041325 · Cited by 4 · see citing works
Napoé, G. S., Luchristt, D., Sridhar, A., Ellington, D. R., Ridgeway, B., Mazloomdoost, D., Sung, V. W., Ninivaggio, C. S., Harvie, H. S., Santiago‐Lastra, Y., et al. (2022) · International Urogynecology Journal · doi:10.1007/s00192-022-05411-2 · Cited by 3 · see citing works
Self-citationHu, P., Liu, L., Dai, L., Wang, Y., & Lei, L. (2023) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.15799 · Cited by 3 · see citing works
Fitzgerald, J. J., Sokol, E. R., Rardin, C. R., Cundiff, G. W., Paraiso, M. F. R., Chou, J., & Gutman, R. E. (2022) · Urogynecology · doi:10.1097/spv.0000000000001188 · Cited by 3 · see citing works
Self-citationNager, C. W. (2022) · Urogynecology · doi:10.1097/spv.0000000000001239 · Cited by 2 · see citing works
Self-citationSacrospinous Hysteropexy With Mesh vs Vaginal Hysterectomy for Treatment of Uterovaginal Prolapse
Nager, C. W., Visco, A. G., Richter, H. E., Rardin, C. R., Meriwether, K., Harvie, H. S., Zyczynski, H. M., Paraiso, M. F. R., Mazloomdoost, D., Sridhar, A., et al. (2026) · JAMA Surgery · doi:10.1001/jamasurg.2026.2263 · Cited by 2 · see citing works
Self-citationA Meta-analysis of the Efficacy of Different Surgical Methods in the Treatment of Uterine Prolapse
Chen, H., Wei, X., Kurexi, N., & Yang, S. (2024) · Annali Italiani di Chirurgia · doi:10.62713/aic.3385 · Cited by 2 · see citing works
Vaginale Rekonstruktionstechniken des Beckenbodens
Fink, T. (2025) · Die Urologie · doi:10.1007/s00120-025-02591-9 · Cited by 1 · see citing works
Management of the Uterus During Prolapse Surgery: Hysterectomy vs Uterine Preservation
Yacoel, T., Yarborough, C. C., Amin, K. A., & Syan, R. (2026) · Current Bladder Dysfunction Reports · doi:10.1007/s11884-025-00798-2 · Cited by 1 · see citing works
Sacrospinous Fixation and Vaginal Uterosacral Suspension—Evaluation in Uterine Preservation Surgery
Woodburn, K. L., Yuan, A. S., Torosis, M., Roberts, K., Ferrando, C. A., & Gutman, R. E. (2022) · Urogynecology · doi:10.1097/spv.0000000000001304 · Cited by 2 · see citing works
Levator Ani Avulsion in Ultrasound Increases Recurrence in Sacrospinous Fixation
Maluenda, A., Santis‐Moya, F., Arévalo-Vega, D., Pohlhammer, D. S., Bernardita Blümel, M., Guzman-Rojas, R. A., & Pizarro‐Berdichevsky, J. (2023) · Urogynecology · doi:10.1097/spv.0000000000001425 · Cited by 1 · see citing works
To err is human: lessons from prolapse studies to identify and strategies to reduce data errors
Myers, D. L., Werth, A. J., Whitworth, R., Menefee, S. A., Visco, A. G., Andy, U. U., Rahn, D. D., Meyer, I., Zyczynski, H. M., & Mazloomdoost, D. (2025) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.08.017 · Cited by 2 · see citing works
Self-citationQiu, B. Q., Wang, A., Chen, Y., & Wang, Z. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/2585529 · Cited by 1 · see citing works
RetractedManagement of Vaginal Posterior Compartment Prolapse: Is There Ever a Case for Graft/Mesh?
Chang, O. H., & Sutherland, S. E. (2023) · Springer eBooks · doi:10.1007/978-3-031-19598-3_38 · Cited by 1 · see citing works
Vaginal mesh hysteropexy: a review
DiCarlo-Meacham, A., & Mazloomdoost, D. (2021) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000748
Self-citationSakrospinale Hysteropexie vs. vaginale Hysterektomie bei uterovaginalem Prolaps
Lichert, F. (2021) · Geburtshilfe und Frauenheilkunde · doi:10.1055/a-1631-6213
Comparison of 2 Geographic Prolapse Surgery Registries
Shah, N. M., & Menefee, S. A. (2022) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2022.08.025
Where Are We Now? Urogynecologic Mesh and Present Recommendations
Gee, A. D., Chapman, G. C., & Paraiso, M. F. R. (2022) · Journal of Gynecologic Surgery · doi:10.1089/gyn.2022.0051
Self-citationOptions and outcomes for uterine preservation at the time of prolapse surgery
Woodburn, K. L. (2022) · OBG Management · doi:10.12788/obgm.0229
Hu, P., Lubin, L. I. U., Wei, L., Ying, W. A. N. G., & Li, L. (2023) · Research Square · doi:10.21203/rs.3.rs-2462893/v1
Management of Vaginal Posterior Compartment Prolapse: Is There Ever a Case for Graft/Mesh?
Chang, O. H., & Sutherland, S. E. (2023) · Springer eBooks · doi:10.1007/978-3-030-71112-2_38-1
Iglesia, C. B. (2023) · Urogynecology · doi:10.1097/spv.0000000000001408
The Distortion of the Composite Prism
Matthews, C. A. (2024) · JAMA Surgery · doi:10.1001/jamasurg.2024.1207
At the Scrub Sink: Uterine Preservation Surgery
Meyer, I. (2024) · Urogynecology · doi:10.1097/spv.0000000000001531
The Pelvic Floor Disorders Network: Evolution Over Two Decades of Female Pelvic Floor Research
Richter, H. E., Visco, A. G., Brubaker, L. T., Sung, V. W., Nygaard, I. E., Arya, L. A., Menefee, S. A., Zyczynski, H. M., Schaffer, J. I., Rogers, R. G., et al. (2024) · Urogynecology · doi:10.1097/spv.0000000000001571
Self-citationIncorporating Perineorrhaphy into the LeFort Colpocleisis: A Modified Surgical Approach
Telek, S. B., Martin, B. S., & Harmanli, O. (2025) · International Urogynecology Journal · doi:10.1007/s00192-025-06041-0
Repair of Advanced Pelvic Organ Prolapse Using an Anchorless Vaginal Implant
Fridman-Kogan, Z., Marcus-Braun, N., & Levy, G. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1009890
Kılıççı, Ç., Karakuş, R., İşcan, R. G., Karakuş, S. S., Tosun, Ö., Uzun, M. G., & Aran, T. (2025) · International Urogynecology Journal · doi:10.1007/s00192-025-06305-9
The EnPlace® Device for Advanced Apical Prolapse: Anatomical Outcomes and Long-Term Satisfaction
Rotem, R., Neuman, J., Hirsch, A., Neuman, M., & Weintraub, A. Y. (2026) · Uro · doi:10.3390/uro6040027
Wolff, D. T., D'Amico, M. J., Santis‐Moya, F., Koven, A. B., Antosh, D. D., Rotem, R., Schmeil, I., Pizarro-Berdichevsky, J., Deprest, J. A., Kang, K., et al. (2026) · International Urogynecology Journal · doi:10.1007/s00192-026-06933-9
- Authors
- Nager, C. W., Visco, A. G., Richter, H. E., Rardin, C. R., Komesu, Y., Harvie, H. S., Zyczynski, H. M., Paraiso, M. F. R., Mazloomdoost, D., Sridhar, A., & Thomas, S.
- Affiliations
- UC San Diego Health System (US)
- Duke Medical Center (US)
- University of Alabama at Birmingham (US)
- Brown University (US)
- University of New Mexico (US)
- University of Pennsylvania (US)
- Magee-Womens Research Institute (US)
- Cleveland Clinic (US)
- National Institutes of Health (US)
- RTI International (US)
- Corresponding author
- Nager, Charles W.
- ORCID
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2021-08
- Volume
- 225
- Issue
- 2
- Pages
- 153.e1-153.e31
- ISSN
- 0002-9378 (ISSN-L)
- PMC
- PMC8328912
- OpenAlex
- W3137134282
- Cited by
- 67
- References
- 24
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 12 · 2023: 14 · 2022: 22 · 2021: 2
- FWCI
- 9.40
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (am, 361 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- American Journal of Obstetrics and Gynecology (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Boston Scientific Corp
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Topics
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Keywords
- uterovaginal prolapse, vaginal hysterectomy, uterosacral ligament suspension, treatment failure, postmenopausal women, long-term outcomes, POP-Q, surgical complications, mesh removal, pelvic floor dysfunction, randomized controlled trials
- MeSH terms
- Patient Reported Outcome Measures, Aged, Female, Humans, Hysterectomy, Vaginal, Ligaments, Middle Aged, Sacrum, Gynecologic Surgical Procedures, Surgical Mesh, Suture Techniques, Uterine Prolapse, Treatment Failure, Plastic Surgery Procedures
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
