The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Endothelial Cell Calcium Signaling during Barrier Function and Inflammation
Open accessAbstract
Calcium is an essential second messenger in endothelial cells and plays a pivotal role in regulating a number of physiological processes including cell migration, angiogenesis, barrier function, and inflammation. An increase in intracellular Ca2+ concentration can trigger a number of diverse signaling pathways under both physiologic and pathologic conditions. In this review we will specifically discuss how calcium signaling pathways in endothelial cells play an essential role in affecting barrier function and facilitating inflammation. Inflammatory mediators such as thrombin and histamine increase intracellular calcium levels. This calcium influx causes adherens junctions disassembly and cytoskeletal rearrangements to facilitate endothelial cell retraction and increased permeability. During inflammation endothelial cell calcium entry and the calcium-related signaling events also help facilitate several leukocyte-endothelial cell interactions such as leukocyte rolling, adhesion, and ultimately transendothelial migration.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Clapham, D. E. (2007) · Cell · doi:10.1016/j.cell.2007.11.028 · Cited by 4,175
Cited by
Microglia polarization from M1 to M2 in neurodegenerative diseases
Guo, S., Wang, H., & Yin, Y. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.815347 · Cited by 920
Więckowska-Gacek, A., Mietelska-Porowska, A., Wydrych, M., & Wojda, U. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101397 · Cited by 343
Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials
Miao, J., Ma, H., Yang, Y., Liao, Y., Lin, C., Zheng, J., Yu, M., & Lan, J. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1201982 · Cited by 293
Li, X., Vemireddy, V., Cai, Q., Xiong, H., Kang, P., Li, X., Giannotta, M., Hayenga, H. N., Pan, E., Sirsi, S. R., et al. (2021) · Nano Letters · doi:10.1021/acs.nanolett.1c02996 · Cited by 105
Metadata
- Authors
- Dalal, P. J., Muller, W. A., & Sullivan, D. P.
- Venue
- The American Journal of Pathology
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 190
- Issue
- 3
- Pages
- 535-542
- ISSN
- 0002-9440 (ISSN-L)
- OpenAlex
- W2994635858
- Cited by
- 237
- References
- 1
- FWCI
- 11.45
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Endothelial Cell Calcium Signaling during Barrier Function and Inflammation. https://app.cochat.ai/papers/10.1016/j.ajpath.2019.11.004
- The paper
- Dalal, P. J., Muller, W. A., & Sullivan, D. P. (2020). Endothelial Cell Calcium Signaling during Barrier Function and Inflammation. The American Journal of Pathology. https://doi.org/10.1016/j.ajpath.2019.11.004
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
