The DOI matches its Crossref record; 118 of the 120 references it cites were found in a registry or an index.
Differential Effects of Exercise on Cancer-Related Fatigue During and Following Treatment
Abstract
Context Exercise-induced improvements in cancer-related fatigue may be moderated differentially in patients during and following treatment. These effects have not been reviewed systematically. In accordance with PRISMA guidelines, the population effect size for exercise training on cancer-related fatigue during and following treatment was estimated and the extent to which the effect is differentiated across the time course of treatment and recovery was determined.Evidence acquisition Articles published before August 2011 were retrieved using Google Scholar, MEDLINE, PsycINFO, PubMed, and Web of Science databases. Seventy studies involving 4881 cancer patients during or following treatment were selected. Articles included a cancer-related fatigue outcome measured at baseline and post-intervention and randomized allocation to exercise or non-exercise comparison. From August to October 2011, Hedges' d effect sizes were computed, study quality was evaluated, and random effects models were used to estimate sampling error and population variance.Evidence synthesis Exercise significantly reduced cancer-related fatigue by a mean effect Δ (95% CI) of 0.32 (0.21, 0.43) and 0.38 (0.21, 0.54) during and following cancer treatment, respectively. During treatment, patients with lower baseline fatigue scores and higher exercise adherence realized the largest improvements. Following treatment, improvements were largest for trials with longer durations between treatment completion and exercise initiation, trials with shorter exercise program lengths, and trials using wait-list comparisons.Conclusions Exercise reduces cancer-related fatigue among patients during and following cancer treatment. These effects are moderated differentially over the time course of treatment and recovery. Exercise has a palliative effect in patients during treatment and a recuperative effect post-treatment.
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“Meta-analyses and reviews showed that exercise interventions can effectively reduce CRF21,22,23,24”
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“Moderate intensity aerobic training performed three times per week and for at least 12 weeks or twice weekly combined aerobic plus resistance training lasting 6–12 weeks can significantly reduce depressive symptoms in cancer survivors during and after treatment(18, 19).”
From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [18]
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Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT
Martin Bland, J., & Altman, D. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90837-8 · Cited by 47,965
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Intraclass correlations: Uses in assessing rater reliability.
Shrout, P. E., & Fleiss, J. L. (1979) · Psychological Bulletin · doi:10.1037/0033-2909.86.2.420 · Cited by 24,532
Operating characteristics of a rank correlation test for publication bias
Begg, C. B., & Mazumdar, M. (1994) · Biometrics · doi:10.2307/2533446 · Cited by 16,955
Wasserman, S. S., Hedges, L. V., & Olkin, I. (1988) · Journal of Educational Statistics · doi:10.2307/1164953 · Cited by 10,377
(2000) · Cited by 9,198
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Ali, D. (2022) · Queensland University of Technology · doi:10.5204/thesis.eprints.233465
Fraterman, I., Sacchi, L., Mallo, H. A., Tibollo, V., Glaser, S. L. C., Medlock, S. K., Ronald Cornet, A., Gabetta, M., Gisko, V., Khodakou, V., et al. (2024) · doi:10.2196/preprints.58938
A Fact-Finding Survey of the Concerns of Patients with Cancer: A Network AnalysisPreprint
Yamamoto, K., Tanabe, Y., Nonogaki, K., Okumura, H., Ozaki, H., Kuno, M., Watanabe, S., Takemura, K., Yamanaka, T., Kizawa, R., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4849633/v1
Fraterman, I., Estacio, L., de Ligt, K. M., van der Loo, I., Wilgenhof, S., van de Poll-Franse, L. V., Beets‐Tan, R. G. H., Tissier, R., & Trebeschi, S. (2024) · European Radiology · doi:10.1007/s00330-024-11289-z
Filion, M., Yoon, S. L., Franks, B., Godfrey, D., McClean, C., Bespalec, J., Maslowski, E. L., Wilkie, D. J., & Schwartz, A. L. (2025) · Current Oncology · doi:10.3390/curroncol32020067
Comorbid symptoms in cancer patients and caring for the caregiver
Strander, S. M., Chiu, D., Temel, J. S., Jacobs, J. M., & Forst, D. A. (2025) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2025.2542245 · Cited by 1
Yu, L., Gao, T., Huang, C., Chen, L., Xin, Y., Shi, H., & Wang, T. (2025) · Research Square · doi:10.21203/rs.3.rs-7333022/v1
Psychological benefits of exercise for cancer survivors
Ni, X., Zhu, X., & Li, J. (2025) · Psycho-Oncologie · doi:10.18282/po4630
Henriksson, A., Strandberg, E., Stenling, A., Mazzoni, A.-S., Sjövall, K., Börjeson, S., Raastad, T., Demmelmaier, I., Berntsen, S., & Nordin, K. (2023) · Figshare · doi:10.6084/m9.figshare.22612075
Etude de la multidimensionnalité de la fatigue associée au cancer du sein non-métastasique
Agier, S. (2019) · theses.fr (ABES) · doi:10.70675/3077b0ffz266fz4b6fz806fzc8189bd16910
Health Behaviors and Breast Cancer Survivorship
Meglio, A. D. (2020) · theses.fr (ABES) · doi:10.70675/519b6c32z4ec6z4b98zb8dbzd96ad6e4a24a
Hendawy, M., Abouzid, M., Alnajjar, A. Z., Elnagar, M., Rzk, F. M., Daniel, J. M., Elshazly, H. M., & Saad, M. M. (2026) · Journal of Medical Science · doi:10.20883/medical.e1320
Treating conditions associated with painful stimuli
Spasić, J. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-30050-9.00009-6
Faria-Silva, T., & Reis-Pina, P. (2026) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2026.103300
Javeth, A., D’silva, F., & Singh, P. (2026) · Indian Journal of Palliative Care · doi:10.25259/ijpc_182_2025
Palliative care in oncology: Symptom management and supportive therapies
Sarma, G., Nath, J., & Medhi, P. P. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-38307-6.00007-7
Metadata
- Authors
- Puetz, T. W., & Herring, M. P.
- Affiliations
- Emory University (US)
- University of Alabama at Birmingham (US)
- Corresponding author
- Puetz, Timothy W.
- ORCID
- Herring, Matthew P.
- Venue
- American Journal of Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2012-08
- Volume
- 43
- Issue
- 2
- Pages
- e1-e24
- ISSN
- 0749-3797 (ISSN-L)
- OpenAlex
- W2069263322
- Cited by
- 219
- References
- 120
- Citations by year
- 2026: 10 · 2025: 9 · 2024: 9 · 2023: 10 · 2022: 17 · 2021: 15 · 2020: 22 · 2019: 10 · 2018: 16 · 2017: 23 · 2016: 19 · 2015: 23 · 2014: 18 · 2013: 15 · 2012: 1
- FWCI
- 1.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Keywords
- cancer-related fatigue, exercise training, cancer therapy, exercise adherence, post-treatment recovery
- MeSH terms
- Exercise Therapy, Fatigue, Humans, Neoplasms, Time Factors, Randomized Controlled Trials as Topic, Practice Guidelines as Topic
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