Prevalence of coronary heart disease and carotid arterial thickening in patients with the metabolic syndrome (The ARIC Study)
Abstract
We determined the prevalence of the metabolic syndrome (MS) with the criteria recommended by the National Cholesterol and Education Program, Adult Treatment Panel III report and estimated the magnitude of cross-sectional associations between the MS, coronary heart disease (CHD), and atherosclerosis in 14,502 black and white middle-age patients in the Atherosclerosis Risk in Communities Study. CHD was ascertained by standardized procedures and subclinical atherosclerosis was determined by measuring carotid intimal medial wall thickness using B-mode ultrasonography. The prevalence of MS was 30%, with substantial variation across race and gender subgroups. Among women but not among men, MS was significantly associated with increasing low-density lipoprotein cholesterol. CHD prevalence was 7.4% among those with the MS compared with 3.6% in comparison subjects (p <0.0001). After adjustment for established risk factors, subjects who had MS were 2 times more likely to have prevalent CHD than were those who did not have the syndrome. Among individuals free of CHD and stroke, after adjustment for age, gender, and race/center, the average intimal-medial wall thickness of carotid arteries was greater among those with versus those without MS (747 vs 704 mum, p <0.0001). Thus, MS was significantly associated with the presence of CHD and carotid intimal medial wall thickness. Identification of patients who have MS may provide opportunities to initiate CHD prevention strategies.
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The MS and insulin resistance have been associated with atherosclerosis in cross-sectional studies.
“although the MS and insulin resistance have been associated with atherosclerosis in crosssectional studies, [23][24][25][26]”
From Diabetes, the Metabolic Syndrome, and Angiographic Progression of Coronary Arterial Disease in Postmenopausal Women (2006) · cites this paper as [23]
Cites
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Ford, E. S., Giles, W. H., & Dietz, W. H. (2002) · JAMA · doi:10.1001/jama.287.3.356 · Cited by 6,698 · see citing works
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
Lakka, H.-M. (2002) · JAMA · doi:10.1001/jama.288.21.2709 · Cited by 5,033 · see citing works
Cardiovascular Morbidity and Mortality Associated With the Metabolic Syndrome
Isomaa, B., Almgren, P., Tuomi, T., Forsén, B., Lahti, K., Nissén, M., Taskinen, M.-R., & Groop, L. (2001) · Diabetes Care · doi:10.2337/diacare.24.4.683 · Cited by 4,760 · see citing works
A short questionnaire for the measurement of habitual physical activity in epidemiological studies
Baecke, J. A. H., BUREMA, J., & Frijters, J. E. R. (1982) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/36.5.936 · Cited by 3,950 · see citing works
THE ATHEROSCLEROSIS RISK IN COMMUNIT (ARIC) STUDY: DESIGN AND OBJECTIVES
THE ARIC INVESTIGATORS (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115184 · Cited by 3,491 · see citing works
(1989) · PubMed · Cited by 3,139 · see citing works
Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging.
Pignoli, P., Tremoli, E., Poli, A., Oreste, P., & Paoletti, R. (1986) · Circulation · doi:10.1161/01.cir.74.6.1399 · Cited by 2,404 · see citing works
Park, Y.-W., Zhu, S., Palaniappan, L., Heshka, S., Carnethon, M. R., & Heymsfield, S. B. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.4.427 · Cited by 2,074 · see citing works
Chambless, L. E., Heiss, G., Folsom, A. R., Rosamond, W., Szklo, M., Sharrett, A. R., & Clegg, L. X. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009302 · Cited by 1,990 · see citing works
Self-citationAlexander, C. M., Landsman, P. B., Teutsch, S. M., & Haffner, S. M. (2003) · Diabetes · doi:10.2337/diabetes.52.5.1210 · Cited by 1,475 · see citing works
Laaksonen, D. E. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf145 · Cited by 916 · see citing works
Ninomiya, J. K., L'Italien, G. J., Criqui, M. H., Whyte, J. L., Gamst, A. C., & Chen, R. S. (2003) · Circulation · doi:10.1161/01.cir.0000108926.04022.0c · Cited by 793 · see citing works
Clustering of metabolic factors and coronary heart disease
Wilson, P. W. F., Kannel, W. B., Silbershatz, H., & D'Agostino, R. B. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.10.1104 · Cited by 712 · see citing works
A Comparison of the Prevalence of the Metabolic Syndrome Using Two Proposed Definitions
Ford, E. S., & Giles, W. H. (2003) · Diabetes Care · doi:10.2337/diacare.26.3.575 · Cited by 616 · see citing works
Elevated Risk of Cardiovascular Disease Prior to Clinical Diagnosis of Type 2 Diabetes
Hu, F. B., Stampfer, M. J., Haffner, S. M., Solomon, C. G., Willett, W. C., & Manson, J. E. (2002) · Diabetes Care · doi:10.2337/diacare.25.7.1129 · Cited by 552 · see citing works
Haffner, S. M., Mykkänen, L. M., Festa, A., Burke, J. P., & D, M. P. S. M. (2000) · Circulation · doi:10.1161/01.cir.101.9.975 · Cited by 454 · see citing works
Carotid Atherosclerosis and Coronary Heart Disease in the Metabolic Syndrome
Bonora, E., Kiechl, S. J., Willeit, J., Oberhollenzer, F., Egger, G., Bonadonna, R. C., & Muggeo, M. (2003) · Diabetes Care · doi:10.2337/diacare.26.4.1251 · Cited by 332 · see citing works
Richardson, M. T., Ainsworth, B. E., WU, H.-C., Jacobs, D. R., & Leon, A. S. (1995) · International Journal of Epidemiology · doi:10.1093/ije/24.4.685 · Cited by 227 · see citing works
The metabolic syndrome, diabetes, and subclinicalatherosclerosis assessed by coronary calcium
Wong, N. D., Sciammarella, M. G., Polk, D. M., Gallagher, A. M., Miranda-Peats, L., Whitcomb, B. W., Hachamovitch, R., Friedman, J. D., Hayes, S. W., & Berman, D. S. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00193-1 · Cited by 220 · see citing works
Chambless, L. E., Zhong, M. M., Arnett, D. K., Folsom, A. R., Riley, W. A., & HEISS, G. M. (1996) · Ultrasound in Medicine & Biology · doi:10.1016/0301-5629(96)00039-7 · Cited by 84 · see citing works
Self-citationAlberti (1998) · doi:10.1002/(sici)1096-9136(199807)15:7
Flagged first, then by citations
1 of the 25 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961 · see citing works
Heart Disease and Stroke Statistics—2006 Update
Writing Group Members, Thom, T., Haase, N., Rosamond, W. D., Howard, V. J., Rumsfeld, J. S., Manolio, T. A., Zheng, Z., Flegal, K. M., O’Donnell, C. J., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.171600 · Cited by 3,453 · see citing works
Self-citationBrott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31820d8d78 · Cited by 797 · see citing works
Brott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.11.005 · Cited by 526 · see citing works
Brott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.11.006 · Cited by 448 · see citing works
Diagnosis and management of the metabolic syndrome
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Current Opinion in Cardiology · doi:10.1097/01.hco.0000200416.65370.a0 · Cited by 434 · see citing works
The metabolic syndrome and risk of incident colorectal cancer
Ahmed, R. L., Schmitz, K. H., Anderson, K. E., Rosamond, W. D., & Folsom, A. R. (2006) · Cancer · doi:10.1002/cncr.21950 · Cited by 326 · see citing works
Self-citationInsulin Resistance and Atherosclerosis
Nigro, J., Osman, N., Dart, A. M., & Little, P. J. (2006) · Endocrine Reviews · doi:10.1210/er.2005-0007 · Cited by 317 · see citing works
n−3 Fatty acids and the metabolic syndrome
Carpentier, Y., Portois, L., & Malaisse, W. J. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.6.1499s · Cited by 283 · see citing works
Brott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.22983 · Cited by 255 · see citing works
Horn, D. J., Okie, J. G., Buelow, H. N., Gooseff, M. N., Barrett, J., & Takacs‐Vesbach, C. D. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.03414-13 · Cited by 234 · see citing works
Malik, S., Budoff, M. J., Katz, R., Blumenthal, R. S., Bertoni, A. G., Nasir, K., Szklo, M., Barr, R. G., & Wong, N. D. (2011) · Diabetes Care · doi:10.2337/dc11-0816 · Cited by 203 · see citing works
Subclinical atherosclerosis: what it is, what it means and what we can do about it
Toth, P. P. (2008) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2008.01804.x · Cited by 187 · see citing works
Brott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Stroke · doi:10.1161/str.0b013e3182112cc2 · Cited by 174 · see citing works
Metabolic Syndrome, Diabetes, and Incidence and Progression of Coronary Calcium
Wong, N. D., Nelson, J. C., Granston, T., Bertoni, A. G., Blumenthal, R. S., Carr, J. J., Guerci, A. D., Jacobs, D. R., Kronmal, R. A., Liu, K., et al. (2012) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2011.12.015 · Cited by 162 · see citing works
Brott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Stroke · doi:10.1161/str.0b013e3182112d08 · Cited by 159 · see citing works
Association of the metabolic syndrome with intracranial atherosclerotic stroke
Bang, O. Y., Kim, J. W., Lee, J. H., Lee, M. A., Lee, P. H., Joo, I. S., & Huh, K. H. (2005) · Neurology · doi:10.1212/01.wnl.0000168862.09764.9f · Cited by 146 · see citing works
Rincón, F., Sacco, R. L., Kranwinkel, G., Xu, Q., Paik, M. C., Boden-Albala, B. M., & Elkind, M. S. V. (2009) · Cerebrovascular Diseases · doi:10.1159/000219299 · Cited by 138 · see citing works
Diagnosis and management of the metabolic syndrome in obesity
Liberopoulos, E. N., Mikhailidis, D. P., & Elisaf, M. (2005) · Obesity Reviews · doi:10.1111/j.1467-789x.2005.00221.x · Cited by 129 · see citing works
Metabolic Syndrome and Early-Onset Coronary Artery Disease
Iribarren, C., Go, A. S., Husson, G., Sidney, S. S., Fair, J. M., Quertermous, T., Hlatky, M. A., & Fortmann, S. P. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.03.070 · Cited by 121 · see citing works
Brott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31820d8c98 · Cited by 118 · see citing works
Kadayıfçı, A., Tan, V. S., Ursell, P. C., Merriman, R. B., & Bass, N. M. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.05.024 · Cited by 116 · see citing works
Ingelsson, E., SULLIVAN, L. M., Murabito, J. M., Fox, C. S., Benjamin, E. J., Polak, J. F., Meigs, J. B., Keyes, M. J., O’Donnell, C. J., Wang, T. J., et al. (2007) · Diabetes · doi:10.2337/db07-0078 · Cited by 113 · see citing works
Callahan, A. S., III (2011) · Archives of Neurology · doi:10.1001/archneurol.2011.146 · Cited by 112 · see citing works
Insulin Resistance, Metabolic Syndrome, and Subclinical Atherosclerosis
Bertoni, A. G., Wong, N. D., Shea, S., Ma, S., Liu, K., Srikanthan, P., Jacobs, D. R., Wu, C. O., Saad, M. F., & Szklo, M. (2007) · Diabetes Care · doi:10.2337/dc07-1042 · Cited by 107 · see citing works
Noninvasive assessment of preclinical atherosclerosis
Lane, H. A., Smith, J. C., & Davies, J. S. (2006) · Vascular Health and Risk Management · doi:10.2147/vhrm.2006.2.1.19 · Cited by 104 · see citing works
Painschab, M., Dávila‐Román, V. G., Gilman, R. H., Vasquez-Villar, A., Pollard, S. L., Wise, R. A., Miranda, J. J., Checkley, W., & CRONICAS Cohort Study Group (2013) · Heart · doi:10.1136/heartjnl-2012-303440 · Cited by 100 · see citing works
Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study
Ballantyne, C. M., Hoogeveen, R. C., McNeill, A. M., HEISS, G. M., Schmidt, M. I., Duncan, B. B., & Pankow, J. S. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.31 · Cited by 98 · see citing works
Self-citationChichlowska, K. L., Rose, K. M., Roux, A. V. D., Golden, S. H., McNeill, A., & HEISS, G. M. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318183a491 · Cited by 96 · see citing works
Self-citationAhluwalia, N., Drouet, L. O., Ruidavets, J., Perret, B., Amar, J., Boccalon, H., Hanaire, H. P., & Ferrières, J. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.07.021 · Cited by 93 · see citing works
Brott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Vascular Medicine · doi:10.1177/1358863x11399328 · Cited by 94 · see citing works
Sobieszczyk, M. E., Hoover, D. R., Anastos, K., Mulligan, K. M., Tan, T., Shi, Q., Gao, W., Hyman, C. L., Cohen, M. H., Cole, S. R., et al. (2008) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31817af461 · Cited by 93 · see citing works
Wilson, M., Wolf, P. A., Sidney, S. S., Sorlie, P. D., Steinberger, J., Wasserthiel-Smoller, S., Furie, K. L., Gorelick, P. B., D, B. M. K. M., Marler, J. M., et al. (2009) · Cited by 83 · see citing works
Self-citationChichlowska, K. L., Rose, K. M., Roux, A. V. D., Golden, S. H., McNeill, A., & HEISS, G. M. (2009) · Annals of Epidemiology · doi:10.1016/j.annepidem.2009.07.094 · Cited by 80 · see citing works
Self-citationMok, C., Poon, W., Lai, J., Wong, C., Chiu, S., Wong, C., Lun, S., Ko, G., Lam, C., & Lam, C. (2010) · Scandinavian Journal of Rheumatology · doi:10.3109/03009740903046668 · Cited by 79 · see citing works
Metabolic Syndrome Amplifies the LDL-Cholesterol Associated Increases in Carotid Atherosclerosis
Kawamoto, R., Tomita, H., Oka, Y., Kodama, A., & Kamitani, A. (2005) · Internal Medicine · doi:10.2169/internalmedicine.44.1232 · Cited by 76 · see citing works
Zanetti, M., Bosutti, A., Ferreira, C., Vinci, P., Biolo, G., Fonda, M., Valente, M., Cattin, L., Guarnieri, G., & Barazzoni, R. (2009) · Clinical and Experimental Medicine · doi:10.1007/s10238-009-0039-z · Cited by 71 · see citing works
Distinct Component Profiles and High Risk Among African Americans With Metabolic Syndrome
Taylor, H. A., Liu, J., Wilson, G. A., Golden, S. H., Crook, E. D., Brunson, C. D., Steffes, M., Johnson, W. D., & Sung, J. H. (2008) · Diabetes Care · doi:10.2337/dc07-1810 · Cited by 69 · see citing works
Self-citationBrott, T. G., Halperin, J. L., Abbara, S., Bacharach, J. M., Barr, J. D., Bush, R. L., Cates, C. U., Creager, M. A., Fowler, S. A., Friday, G. H., et al. (2011) · Journal of NeuroInterventional Surgery · doi:10.1136/jnis.2011.004762 · Cited by 67 · see citing works
Thematic review series: Patient-Oriented Research. Imaging atherosclerosis: state of the art
Crouse, J. R. (2006) · Journal of Lipid Research · doi:10.1194/jlr.r600012-jlr200 · Cited by 66 · see citing works
Barbato, J. E., Zuckerbraun, B. S., Overhaus, M., Raman, K. G., & Tzeng, E. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00982.2004 · Cited by 64 · see citing works
Metabolic Syndrome and the Progression of Carotid Intima-Media Thickness in Elderly Women
Hassinen, M., Komulainen, P., Lakka, T. A., Väisänen, S., Haapala, I., Gylling, H., Alén, M., Schmidt‐Trucksäss, A., Nissinen, A. M., & Rauramaa, R. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.4.444 · Cited by 64 · see citing works
The Metabolic Syndrome and Its Traits as Risk Factors for Subclinical Atherosclerosis
Holewijn, S., den Heijer, M., Swinkels, D. W., Stalenhoef, A. F. H., & Graaf, J. D. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0084 · Cited by 62 · see citing works
Şengül, C., Çevik, C., Özveren, O., Oduncu, V., Sünbül, A., Akgün, T., Can, M. M., Semiz, E., & Dindar, İ. (2011) · Echocardiography · doi:10.1111/j.1540-8175.2011.01471.x · Cited by 58 · see citing works
Wong, N. D. (2007) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200707040-00004 · Cited by 55 · see citing works
Navigating Complex Sample Analysis Using National Survey Data
Saylor, J. L., Friedmann, E., & Lee, H. J. (2012) · Nursing Research · doi:10.1097/nnr.0b013e3182533403 · Cited by 53 · see citing works
Qin, G., Tu, J., Chenjing, Z., Tang, X., Luo, L., Wu, J., Liu, L., Lu, W., Tao, L., Shen, S., et al. (2015) · Lipids in Health and Disease · doi:10.1186/s12944-015-0023-4 · Cited by 53 · see citing works
Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics
Nolan, D. A., Reiss, P., & Mallal, S. A. (2005) · Expert Opinion on Drug Safety · doi:10.1517/14740338.4.2.201 · Cited by 51 · see citing works
Metabolic syndrome and carotid intima media thickness in the Health 2000 Survey
Sipilä, K., Moilanen, L., Nieminen, T. V. M., Reunanen, A., Jula, A., Salomaa, V. V., Kaaja, R., Kukkonen-Harjula, K. T., Lehtimäki, T. J., Kesäniemi, Y. A., et al. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.08.029 · Cited by 49 · see citing works
Novo, S., Peritore, A., Guarneri, F. P., Corrado, E., Macaione, F., Evola, S., & Novo, G. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.05.018 · Cited by 48 · see citing works
Blaum, C. S., West, N. A., & Haan, M. N. (2007) · The Journals of Gerontology Series A · doi:10.1093/gerona/62.7.766 · Cited by 47 · see citing works
Himeno, T., Kamiya, H., & Nakamura, J. (2019) · Journal of Diabetes Investigation · doi:10.1111/jdi.13173 · Cited by 49 · see citing works
Zhao, Y., Evans, M. A., Allison, M., Bertoni, A. G., Budoff, M. J., Criqui, M. H., Malik, S., Ouyang, P., Polak, J. F., & Wong, N. D. (2018) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2018.12.005 · Cited by 45 · see citing works
Tentolouris, N., Papazafiropoulou, A. K., Moyssakis, I. E., Liatis, S., Perrea, D. N., Kostaki, M., & Katsilambros, N. L. (2008) · Cardiovascular Diabetology · doi:10.1186/1475-2840-7-1 · Cited by 45 · see citing works
The Metabolic Syndrome and Subclinical Carotid Atherosclerosis: The Northern Manhattan Study
Rundek, T., White, H., Boden-Albala, B. M., Jin, Z., Elkind, M. S. V., & Sacco, R. L. (2007) · Journal of the CardioMetabolic Syndrome · doi:10.1111/j.1559-4564.2007.06358.x · Cited by 44 · see citing works
Touboul, P., Vicaut, É., Labreuche, J., Mónica Acevedo, B., Torres, V., Ramírez-Martínez, J. C., Vinueza, R., Silva, H., Champagne, B. M., Hernández-Hernández, R., et al. (2010) · Cerebrovascular Diseases · doi:10.1159/000320264 · Cited by 43 · see citing works
Novo, S., Peritore, A., Trovato, R., Guarneri, F., di Lisi, D., Muratori, I., & Novo, G. (2013) · Cardiovascular Diabetology · doi:10.1186/1475-2840-12-155 · Cited by 43 · see citing works
Girman, C. J., Dekker, J. M., Rhodes, T., Nijpels, G., Stehouwer, C. D. A., Bouter, L. M., & Heine, R. J. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi229 · Cited by 41 · see citing works
Self-citationRelationship of the metabolic syndrome to carotid ultrasound traits
Pollex, R. L., Alshali, K. Z., House, A. A., Spence, J. D., Fenster, A., Mamakeesick, M., Zinman, B., Harris, S. B., Hanley, A. J., & Hegele, R. A. (2006) · Cardiovascular Ultrasound · doi:10.1186/1476-7120-4-28 · Cited by 41 · see citing works
Mellen, P. B., Cefalu, W. T., & Herrington, D. M. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000191656.71812.7c · Cited by 38 · see citing works
Adjei, N. K., Samkange‐Zeeb, F., Boakye, D., Saleem, M., Christianson, L., Kebede, M. M., Heise, T. L., Brand, T., Esan, O. B., Taylor-Robinson, D. C., et al. (2024) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-024-09879-9 · Cited by 38 · see citing works
Mohan, V., Gokulakrishnan, K., Sreedharan, S., Srivastava, B. K., Ravikumar, R., & Deepa, R. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01898.x · Cited by 37 · see citing works
Hepatic steatosis and vascular disease.
Santoliquido, A., Campli, C. D., Miele, L., Gabrieli, M. L., Forgione, A., Zocco, M. A., Lupascu, A., Giorgio, A. D., Flore, R. A., Pola, P., et al. (2005) · PubMed · Cited by 37 · see citing works
Prognostic Relevance of Metabolic Syndrome in Hypertensive Patients at Low-to-Medium Risk
Pierdomenico, S. D., Lapenna, D., DITOMMASO, R., DiCarlo, S. E., CALDARELLA, M., Neri, M., Mezzetti, A., & CUCCURULLO, F. (2007) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2007.06.011 · Cited by 35 · see citing works
Yun, J. E., Won, S., Sung, J., & Jee, S. H. (2012) · Circulation Journal · doi:10.1253/circj.cj-12-0125 · Cited by 33 · see citing works
Ahanchi, S. S., Varu, V. N., Tsihlis, N. D., Martínez, J., Pearce, C. G., Kapadia, M. R., Jiang, Q., Saavedra, J. E., Keefer, L. K., Hrabie, J. A., et al. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00185.2008 · Cited by 33 · see citing works
Itoh, H., Kaneko, H., Kiriyama, H., Yoshida, Y., Nakanishi, K., Mizuno, Y., Daimon, M., Morita, H., Yatomi, Y., Yamamichi, N., et al. (2019) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.48728 · Cited by 32 · see citing works
Sex differences and cardiovascular risk
Cordero, A., & Alegria, E. (2006) · Heart · doi:10.1136/hrt.2005.069187 · Cited by 33 · see citing works
Bolla, E., Tentolouris, N., Sfikakis, P. P., & Tektonidou, M. G. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1077166 · Cited by 32 · see citing works
Metabolic syndrome, cardiovascular risk and screening for subclinical atherosclerosis
Malik, S., & Wong, N. D. (2009) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.7.3.273 · Cited by 32 · see citing works
Paschoal, R. S., Antoniali, D., Cardili, R. N., & Souza, C. D. S. (2018) · Anais Brasileiros de Dermatologia · doi:10.1590/abd1806-4841.20186397 · Cited by 31 · see citing works
Challenges Associated with Metabolic Syndrome
Spinler, S. A. (2006) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.26.12part2.209s · Cited by 30 · see citing works
Bataille, V., Perret, B., Dallongeville, J., Arveiler, D., Yarnell, J., Ducimetière, P., & Ferrières, J. (2006) · Diabetes & Metabolism · doi:10.1016/s1262-3636(07)70306-3 · Cited by 29 · see citing works
Berberine Attenuates Vascular Remodeling and Inflammation in a Rat Model of Metabolic Syndrome
Li, X., Li, C., Xiao, J., Gao, H., Wang, H., Zhang, X., Zhang, C., & Ji, X. (2015) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b14-00828 · Cited by 28 · see citing works
Metabolic Syndrome and Prediabetes
Babu, A. R., & Fogelfeld, L. A. (2006) · Disease-a-Month · doi:10.1016/j.disamonth.2006.03.001 · Cited by 27 · see citing works
Dodani, S., Dong, L., Guirgis, F. W., & Reddy, S. T. (2014) · Archives of Medical Science · doi:10.5114/aoms.2014.46208 · Cited by 26 · see citing works
Modulation of aortic vascular reactivity by sex hormones in a male rat model of metabolic syndrome
Pérez-Torres, I., Hafidi, M. E., Zamora‐González, J., Infante, Ó., Chavira, R., & Baños, G. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.04.006 · Cited by 26 · see citing works
C-Peptide: A New Mediator of Atherosclerosis in Diabetes
Vasic, D., & Walcher, D. (2012) · Mediators of Inflammation · doi:10.1155/2012/858692 · Cited by 26 · see citing works
Hypogonadism and metabolic syndrome: review and update
Berg, W. T., & Miner, M. M. (2020) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000582 · Cited by 25 · see citing works
Yu, R., Ho, S. C., Ho, S. S. Y., Woo, J., & Ahuja, A. T. (2007) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e31806458c9 · Cited by 25 · see citing works
Osteopontin Promoter Polymorphism Is Associated With Increased Carotid Intima-Media Thickness
Fuentes, L. D. L., Gu, C. C., Mathews, S. J., Reagan, J. L., Ruthmann, N. P., Waggoner, A. D., Lai, C., Towler, D. A., & Dávila‐Román, V. G. (2008) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2008.02.005 · Cited by 24 · see citing works
Leng, X., Chen, X. Y., Chook, P., Xiong, L., Lin, W. H., Liu, J. Y., Tomlinson, B., Thomas, G. N., Lam, T. H., Lam, K. S. L., et al. (2013) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2012.0099 · Cited by 24 · see citing works
Xu, L., Jiang, C. Q., Lam, T. H., Lin, J. M., Yue, X. J., Cheng, K. K., Liu, B., Jin, Y. L., Zhang, W. S., & Thomas, G. N. (2009) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03760.x · Cited by 24 · see citing works
Stevenson, J. E., Wright, B. R., & Boydstun, A. S. (2012) · Metabolism · doi:10.1016/j.metabol.2012.04.010 · Cited by 22 · see citing works
Alanine Aminotransferase Is Associated With Metabolic Syndrome Independently of Insulin Resistance
Yun, J. E., Kim, S. Y., Kang, H., Lee, S. J., Kimm, H., & Jee, S. H. (2011) · Circulation Journal · doi:10.1253/circj.cj-10-0465 · Cited by 22 · see citing works
Metabolic syndrome and masked hypertension among African Americans: The Jackson Heart Study
Colantonio, L. D., Anstey, D. E., Carson, A. P., Ogedegbe, G. G., Abdalla, M., Sims, M., Shimbo, D., & Muntner, P. (2017) · Journal of Clinical Hypertension · doi:10.1111/jch.12974 · Cited by 22 · see citing works
Non-High-Density Lipoprotein Cholesterol in Patients with Metabolic Syndrome
Huang, J., Parish, R. C., Mansi, I. A., Yu, H., Kennen, E. M., Davis, T. C., & Carden, D. L. (2008) · Journal of Investigative Medicine · doi:10.2310/jim.0b013e318182080a · Cited by 21 · see citing works
Proinflammatory Effects of C-Peptide in Different Tissues
Vasic, D., & Walcher, D. (2012) · International Journal of Inflammation · doi:10.1155/2012/932725 · Cited by 20 · see citing works
Plasma Pentraxin 3 is Associated with Cardiovascular Disease in Hemodialysis Patients
Xu, Y. X., Ding, X., Zou, J., Liu, Z., Jiang, S., Xu, S., Shen, B., Chen, Y., Shan, Y.-S., & Cao, X. (2011) · Renal Failure · doi:10.3109/0886022x.2011.618969 · Cited by 20 · see citing works
Association Between Carotid Atherosclerosis and Metabolic Syndrome: Results From the ISMIR Study
Antonini‐Canterin, F., Carrubba, S. L., Gullace, G., Zito, C., Bello, V. D., Salvo, G. D., Benedetto, F. A., Novo, S., Pezzano, A., Perticone, F., et al. (2010) · Angiology · doi:10.1177/0003319709360523 · Cited by 19 · see citing works
Metabolic Syndrome and Cardiovascular Risk in Primary Hypertension
Ratto, E., Leoncini, G., Viazzi, F. C., Vaccaro, V., Parodi, A., Falqui, V., Conti, N. E., Tomolillo, C., Deferrari, G., & Pontremoli, R. (2006) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005121328 · Cited by 19 · see citing works
Umeh, O. C., & Currier, J. S. (2005) · Current HIV/AIDS Reports · doi:10.1007/s11904-005-0006-6 · Cited by 19 · see citing works
Yokota, C., Minematsu, K., Ito, A., Toyoda, Ḱ., Nagasawa, H., & Yamaguchi, T. (2008) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2008.10.002 · Cited by 18 · see citing works
Manzato, E., Romanato, G., Zambon, S., Corti, M. C., Baggio, G., Sartori, L., Musacchio, E., Zanoni, S., Marin, R., & Crepaldi, G. (2008) · Aging Clinical and Experimental Research · doi:10.1007/bf03324747 · Cited by 17 · see citing works
Antonini‐Canterin, F., Leiballi, E., Capanna, M., Burelli, C., Cassin, M., Macor, F., Grandis, U., & Nicolosi, G. L. (2008) · Angiology · doi:10.1177/0003319708327646 · Cited by 17 · see citing works
Kiriş, İ., Tekin, İ., Yeşildağ, A., Vural, H., Oyar, O., Sirin, B., Okutan, H., & İbrişim, E. (2006) · International Heart Journal · doi:10.1536/ihj.47.855 · Cited by 17 · see citing works
Jae, S. Y., Franklin, B. A., Schmidt‐Trucksäss, A., Kim, D. K., Choi, Y., & Park, J. B. (2016) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.07.064 · Cited by 16 · see citing works
Chronic Mild Hyperglycemia in GCK-MODY Patients Does Not Increase Carotid Intima-Media Thickness
Průhová, Š., Dušátková, P., Kraml, P. J., Kulich, M., Prochazkova, Z., Brož, J., Zikmund, J., Cinek, O., Anděl, M., Pedersen, O. B., et al. (2013) · International Journal of Endocrinology · doi:10.1155/2013/718254 · Cited by 16 · see citing works
Physical Activity, Stress, and Obesity
Holmes, M. E. (2017) · Springer eBooks · doi:10.1007/978-3-662-49322-9_13 · Cited by 15 · see citing works
Al-Nimer, M. S. M., & Hussein, I. I. (2009) · International Journal of Diabetes in Developing Countries · doi:10.4103/0973-3930.50710 · Cited by 15 · see citing works
- Authors
- McNeill, A. M., Rosamond, W. D., Girman, C. J., Heiss, G., Golden, S. H., Duncan, B. B., East, H. E., & Ballantyne, C.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Johns Hopkins University (US)
- Universidade Federal do Rio Grande do Sul (BR)
- University of Mississippi Medical Center (US)
- Baylor College of Medicine (US)
- Corresponding author
- Rosamond, Wayne D.
- ORCID
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2004-11
- Volume
- 94
- Issue
- 10
- Pages
- 1249-1254
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W2084016774
- Cited by
- 177
- References
- 25
- Citations by year
- 2024: 2 · 2023: 1 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 4 · 2016: 8 · 2015: 4 · 2014: 6 · 2013: 6 · 2012: 12
- FWCI
- 13.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (n01hc55021-47-0-1, n01hc55020-39-0-0, n01hc55016-37-0-0, n01hc055022-024, n01hc55019-35-0-1, n01hc55018-38-0-1, n01hc55015-48-0-1)
- National Heart, Lung, and Blood Institute (N01-HC55022, N01-HC-55018, N01 HC 55020, N01 HC 55019, N01-HC55016, N01‐HC‐55015, N01-HC55021, T32HL007055, 5T32-HL07055)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- metabolic syndrome, coronary artery disease, carotid intima-media thickness, subclinical atherosclerosis, prevalence, racial differences, sex differences, LDL cholesterol, cardiovascular risk factors, Atherosclerosis Risk in Communities Study
- MeSH terms
- Carotid Artery Diseases, Coronary Disease, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Risk Factors, Ultrasonography, Prevalence, Tunica Intima, Tunica Media, Metabolic Syndrome
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